Ppard Rat Gene (peroxisome proliferator-activated receptor delta)

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Keyword

Gene:
Ppard ( Rattus norvegicus )
peroxisome proliferator-activated receptor delta
Description: transcription factor of the nuclear hormone receptor superfamily; may mediate the intestinal expression of target genes implicated in lipid metabolism
Synonyms: Pparb; peroxisome proliferator activated receptor delta; Peroxisome proliferator activator receptor delta; Peroxisome proliferator activator receptor, delta;
ArrayIDs: 1387684_at; U40064_g_at; rc_AI058392_at; 5754806; 6601058; 6076036; 5869833; U40064_at; 5812649; 1374914_at; 5629496; 6189766; rc_AI230294_at; 6365382; 6207993; 5782667; GE21973; 6104917; A_43_P11733; 5627212; 6115467; 6149076; 6200589;  (details...)
Gene Type: protein-coding

Additional Data

primer pair: 634959

Homologs
Homo sapiens: PPARD     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Ppard     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Ppard genome assembly 3.1 20 6479323 - 6543249
Rat Celera Assembly 20 7855175 - 7919043
RH 3.4 20 75.52
RGSC genome assembly v3.4 20 6479092 - 6543024
Cytogenetic 20 p12
Mus musculus Ppard Mouse genome assembly build 36.1 17 28369699 - 28438414
Cytogenetic 17 17 A3.3
Homo sapiens PPARD human genome assembly 6 35418363 - 35501149
Human genome assembly build 36.2 6 35418313 - 35503933
Cytogenetic 6 p21.2-p21.1

View comparative maps:      NCBI MapViewer

Genome
View:

Browsers:

Annotation
Molecular Function

Gene Ontology

NF-kappaB binding,  zinc ion binding,  transcription factor activity ... (details...)
Biological Process

Gene Ontology

vitamin A metabolic process,  adipose tissue development,  regulation of transcription, DNA-dependent ... (details...)
Cellular Component

Gene Ontology

nucleus (details...)
Disease

Ontology

Diabetes Mellitus, Experimental,  Insulin Resistance,  Obesity ... (details...)
Expression

Note Reference

expressed in all tissues except adipose tissue; enriched in the digestive tract, kidney, heart, diaphragm, and esophagus 633659

External Links
Databases
DATABASE ID SOURCE
SMART: ZnF_C4 IPI
SMART: HOLI IPI
PROSITE: NUCLEAR_REC_DBD_2 IPI
PROSITE: NUCLEAR_REC_DBD_1 IPI
UNIPARC: UPI00000E7DAF IPI
KEGG Report: rno:25682 ENTREZGENE
HomoloGene Group ID: 4544 ENTREZGENE
Germonline: 3370
Pfam: Hormone_recep IPI
Pfam: zf-C4 IPI
KEGG Pathway: 04310 ENTREZGENE
KEGG Pathway: 03320 ENTREZGENE
InterPro: 1Cnucl_rcpt_B. IPI
InterPro: 1Cnucl_rcpt. IPI
InterPro: Str_hrmn_rcpt. IPI
InterPro: Nucl_hrmn_rcpt_lig-bd_core. IPI
InterPro: Nucl_hormone_rcpt_ligand-bd. IPI
InterPro: Znf_NHR/GATA. IPI
InterPro: Znf_hrmn_rcpt. IPI
IPI: IPI00325169 IPI
Ensembl Protein: ENSRNOP00000045974 IPI
Gene3D-CATH: Nucl_hrmn_rcpt_lig_bd IPI
Gene3D-CATH: Znf_NHR/GATA IPI
Entrez Gene: Ppard ENTREZGENE
UniProt: Q99ND3_RAT IPI
UniProt: Q9QWI0_RAT IPI
UniProt: Q62879_RAT IPI
Ensembl Genes: ENSRNOG00000000503 IPI
RatMap: 44419 ENTREZGENE
Superfamily-SCOP: Str_ncl_receptor IPI
PRINTS: STROIDFINGER. IPI
PRINTS: PROXISOMEPAR. IPI
PRINTS: STRDHORMONER. IPI
PRINTS: PROXISOMPABR. IPI
Sequences
Nucleotide: CK356918 Get FASTA Search GEO Profiles
Nucleotide: AJ306400 Get FASTA Search GEO Profiles
Nucleotide: CH473988 Get FASTA Search GEO Profiles
Nucleotide: NM_013141 Get FASTA Search GEO Profiles
Nucleotide: CB326159 Get FASTA Search GEO Profiles
Nucleotide: AW143792 Get FASTA Search GEO Profiles
Nucleotide: CO560438 Get FASTA Search GEO Profiles
Nucleotide: FM033221 Get FASTA Search GEO Profiles
Nucleotide: U40064 Get FASTA Search GEO Profiles
Nucleotide: U75918 Get FASTA Search GEO Profiles
(View all 10 Nucleotide Accessions)
Protein: Q9QWI0 Get FASTA
Protein: Q99ND3 Get FASTA
Protein: Q62879 Get FASTA
Protein: AAC65985 Get FASTA
Protein: AAC52419 Get FASTA
Protein: CAC29088 Get FASTA
Protein: EDL96915 Get FASTA
Protein: EDL96914 Get FASTA
Protein: EDL96913 Get FASTA
Protein: NP_037273 Get FASTA
(View all 10 Protein Accessions)
Clusters
UniGene: 96181

References
Curated References
16 references in RGD related to Ppard

Other References
30 other references at PubMed related to Ppard

Database Information
RGD ID 3370
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

15-FEB-08: Ppard peroxisome proliferator-activated receptor delta Ppard peroxisome proliferator activated receptor delta APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

09-APR-03: Ppard peroxisome proliferator activated receptor delta Peroxisome proliferator activator receptor, delta APPROVED Name updated 629478

10-JUN-02: Ppard Peroxisome proliferator activator receptor, delta APPROVED Symbol and Name status set to approved 70586