Plcb4 Rat Gene (phospholipase C, beta 4)

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Keyword

Gene:
Plcb4 ( Rattus norvegicus )
phospholipase C, beta 4
Description: phospholipase C isozyme; may play a role in phototransduction
Synonyms: Phospholipase C beta4; RATBETA4AA; Phospholipase C (BETA4); Beta4aa;
ArrayIDs: 6120802; 5888155; 5879754; A_44_P340163; 6289313; 6424782; 6337758; 6115909; L15556_at; 6744878; 6086039; 6213803; 1386962_at; 6573280; A_42_P537534; 6606888; 5985401; 6031727; 6297471; 5775003; 5935980; 6418647; 5964806; 6448124; 1370489_a_at; 6702831; 5942257; 6030624; 6293009; 5927267; 6304671; 6009958; 6034868; GE1261902; 5779949; 6265578; 6546873; 6385960; 6032377; 6141533; 6588333; 6367307; 6575867; 6559245; 6548075; AF027571_s_at; 6112655; 5852465; 6406100; 6213855; 5748228; 6079302; 6275915; 5863610;  (details...)
Gene Type: protein-coding

Additional Data

Markers: D3Wox21

Homologs
Homo sapiens: PLCB4     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Plcb4     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Plcb4     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Plcb4 genome assembly 3.1 3 123611885 - 123982941
Rat Celera Assembly 3 121694557 - 122062160
RGSC genome assembly v3.4 3 123699299 - 124077381
Cytogenetic 3 q36
Mus musculus Plcb4 Mouse genome assembly build 36.1 2 135567566 - 135838804
Cytogenetic 2 2 F3
Homo sapiens PLCB4 human genome assembly 20 9024931 - 9409460
Human genome assembly build 36.2 20 9024932 - 9409463
Cytogenetic 20 p12

View comparative maps:      NCBI MapViewer

Genome
View:

Browsers:

Other Map Data:
Associated SSLP Map Locations
No mapping information currently available in RGD for D3Wox21

Annotation
Molecular Function

Gene Ontology

protein binding,  mitogen-activated protein kinase binding (details...)
Biological Process

Gene Ontology

phototransduction,  negative regulation of potassium ion transport (details...)
Cellular Component

Gene Ontology

nucleus,  cytoplasm,  smooth endoplasmic reticulum ... (details...)
Phenotype

Ontology

abnormal circadian phase (details...)
Pathway

Ontology

inositol phosphate metabolic pathway,  Wnt signaling pathway (details...)
Homology

Note Reference

has 50% amino acid identity with D. melanogastar norpA 633574

External Links
Databases
DATABASE ID SOURCE
SMART: PLCYc IPI
SMART: PLCXc IPI
SMART: C2 IPI
PROSITE: PIPLC_Y_DOMAIN IPI
PROSITE: C2 IPI
PROSITE: PIPLC_X_DOMAIN IPI
UNIPARC: UPI000002B10D IPI
UNIPARC: UPI0000131A95 IPI
UNIPARC: UPI0001B7B34B IPI
UNIPARC: UPI000002B10E IPI
KEGG Report: rno:25031 ENTREZGENE
HomoloGene Group ID: 8471 ENTREZGENE
Germonline: 3345
Pfam: PI-PLC-Y IPI
Pfam: PI-PLC-X IPI
Pfam: efhand_like IPI
Pfam: C2 IPI
Pfam: DUF1154 IPI
KEGG Pathway: 04310 ENTREZGENE
KEGG Pathway: 04270 ENTREZGENE
KEGG Pathway: 04070 ENTREZGENE
KEGG Pathway: 01100 ENTREZGENE
KEGG Pathway: 04916 ENTREZGENE
KEGG Pathway: 04720 ENTREZGENE
KEGG Pathway: 04730 ENTREZGENE
KEGG Pathway: 00562 ENTREZGENE
KEGG Pathway: 05016 ENTREZGENE
KEGG Pathway: 04912 ENTREZGENE
KEGG Pathway: 04540 ENTREZGENE
KEGG Pathway: 04062 ENTREZGENE
KEGG Pathway: 04020 ENTREZGENE
KEGG Pathway: 05010 ENTREZGENE
InterPro: Phospholipase_C_Pinositol-sp_Y. IPI
InterPro: PLC-beta. IPI
InterPro: PLC-like_Pdiesterase_TIM-brl. IPI
InterPro: Phospholipase_C_Pinositol-sp_X. IPI
InterPro: C2_Ca-dep. IPI
InterPro: C2_Ca/lipid-bd_reg_CaLB. IPI
InterPro: C2_membr_targeting. IPI
InterPro: DUF1154. IPI
InterPro: EF-Hand_type. IPI
InterPro: Phospholipase_C_EF-hand-like. IPI
InterPro: Phospholipase_C_Pinositol-sp_C. IPI
Ensembl Protein: ENSRNOP00000060698 IPI
Ensembl Protein: ENSRNOP00000048775 IPI
Ensembl Protein: ENSRNOP00000045972 IPI
Ensembl Protein: ENSRNOP00000048553 IPI
IPI: IPI00951772 IPI
IPI: IPI00231558 IPI
IPI: IPI00565252 IPI
IPI: IPI00231559 IPI
Gene3D-CATH: PLC-like_Pdiesterase_TIM-brl IPI
Gene3D-CATH: EF-Hand_type IPI
Entrez Gene: Plcb4 ENTREZGENE
PIRSF: PLC-beta IPI
Ensembl Genes: ENSRNOG00000033119 IPI
TIGR: TC217862
UniProt: PLCB4_RAT IPI
UniProt: PLCB4_RAT IPI
UniProt: PLCB4_RAT IPI
RatMap: 36445 ENTREZGENE
Superfamily-SCOP: C2_CaLB IPI
Superfamily-SCOP: PLC-like_Pdiesterase_TIM-brl IPI
PRINTS: PHPHLIPASEC. IPI
Sequences
Nucleotide: AF027571 Get FASTA Search GEO Profiles
Nucleotide: U57836 Get FASTA Search GEO Profiles
Nucleotide: NM_024353 Get FASTA Search GEO Profiles
Nucleotide: L18962 Get FASTA Search GEO Profiles
Nucleotide: AF031370 Get FASTA Search GEO Profiles
Nucleotide: L15556 Get FASTA Search GEO Profiles
(View all 6 Nucleotide Accessions)
Protein: AAK13557 Get FASTA
Protein: AAC24984 Get FASTA
Protein: NP_077329 Get FASTA
Protein: AAC98145 Get FASTA
Protein: AAD10403 Get FASTA
Protein: Q9QW07 Get FASTA
(View all 6 Protein Accessions)
Clusters
UniGene: 6155

References
Curated References
12 references in RGD related to Plcb4

Other References
8 other references at PubMed related to Plcb4

Database Information
RGD ID 3345
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

10-JUN-02: Plcb4 Phospholipase C , beta4 APPROVED Symbol and Name status set to approved 70586