Ocm (oncomodulin) - Rat Genome Database

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Gene: Ocm (oncomodulin) Rattus norvegicus
Analyze
Symbol: Ocm
Name: oncomodulin
RGD ID: 3222
Description: Enables calcium ion binding activity and protein homodimerization activity. Involved in cochlea development and response to wounding. Located in several cellular components, including cuticular plate; extracellular space; and stereocilium. Part of protein-containing complex. Orthologous to several human genes including OCM (oncomodulin); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 5-aza-2'-deoxycytidine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ocm2; OM; oncmodulin; oncomodulin 2; parvalbumin beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,649,452 - 15,710,375 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,676,520 - 15,710,379 (+)EnsemblGRCr8
mRatBN7.21210,535,619 - 10,596,705 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,586,897 - 10,596,707 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,393,448 - 11,403,130 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,016,733 - 12,026,415 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,040,043 - 11,050,658 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1217,179,711 - 17,189,322 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1217,105,849 - 17,115,462 (+)NCBILyon_Normotensive
Lyon_Hypertensive1215,956,885 - 15,966,494 (+)NCBILyon_Hypertensive
F344_StmMcwi1226,538,272 - 26,547,520 (+)NCBIF344_StmMcwi
Rnor_6.01212,611,121 - 12,634,472 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,624,723 - 12,634,472 (+)Ensemblrn6Rnor6.0
Rnor_5.01214,619,319 - 14,678,847 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,916,095 - 10,925,595 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,384,375 - 12,394,039 (+)NCBICelera
RGSC_v3.11210,946,022 - 10,955,523 (+)NCBI
Cytogenetic Map12p11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structure of oncomodulin refined at 1.85 A resolution. An example of extensive molecular aggregation via Ca2+. Ahmed FR, etal., J Mol Biol. 1990 Nov 5;216(1):127-40.
2. Refinement of recombinant oncomodulin at 1.30 A resolution. Ahmed FR, etal., J Mol Biol. 1993 Apr 20;230(4):1216-24.
3. Retroviral long terminal repeat is the promoter of the gene encoding the tumor-associated calcium-binding protein oncomodulin in the rat. Banville D and Boie Y, J Mol Biol 1989 Jun 5;207(3):481-90.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. A complete complementary DNA for the oncodevelopmental calcium-binding protein, oncomodulin. Gillen MF, etal., J Biol Chem 1987 Apr 15;262(11):5308-12.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. The concentrations of calcium buffering proteins in mammalian cochlear hair cells. Hackney CM, etal., J Neurosci. 2005 Aug 24;25(34):7867-75.
8. Solution structure of Ca2+-free rat beta-parvalbumin (oncomodulin). Henzl MT and Tanner JJ, Protein Sci. 2007 Sep;16(9):1914-26. doi: 10.1110/ps.072837307.
9. Association of the AB and CD-EF domains from rat alpha- and beta-parvalbumin. Henzl MT, etal., Biochemistry. 2004 Aug 31;43(34):10906-17.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Metal-controlled interdomain cooperativity in parvalbumins. Permyakov SE, etal., Cell Calcium. 2009 Sep;46(3):163-75. Epub 2009 Aug 3.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Cytosolic Ca2+ buffers. Schwaller B, Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a004051. doi: 10.1101/cshperspect.a004051. Epub 2010 Oct 13.
16. Oncomodulin. 1H NMR and optical stopped-flow spectroscopic studies of its solution conformation and metal-binding properties. Williams TC, etal., J Biol Chem. 1987 May 5;262(13):6248-56.
17. Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Yin Y, etal., Nat Neurosci. 2006 Jun;9(6):843-52. Epub 2006 May 14.
Additional References at PubMed
PMID:6617664   PMID:14978725   PMID:19075559   PMID:33419032  


Genomics

Comparative Map Data
Ocm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,649,452 - 15,710,375 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,676,520 - 15,710,379 (+)EnsemblGRCr8
mRatBN7.21210,535,619 - 10,596,705 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,586,897 - 10,596,707 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,393,448 - 11,403,130 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,016,733 - 12,026,415 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,040,043 - 11,050,658 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1217,179,711 - 17,189,322 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1217,105,849 - 17,115,462 (+)NCBILyon_Normotensive
Lyon_Hypertensive1215,956,885 - 15,966,494 (+)NCBILyon_Hypertensive
F344_StmMcwi1226,538,272 - 26,547,520 (+)NCBIF344_StmMcwi
Rnor_6.01212,611,121 - 12,634,472 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,624,723 - 12,634,472 (+)Ensemblrn6Rnor6.0
Rnor_5.01214,619,319 - 14,678,847 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41210,916,095 - 10,925,595 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,384,375 - 12,394,039 (+)NCBICelera
RGSC_v3.11210,946,022 - 10,955,523 (+)NCBI
Cytogenetic Map12p11NCBI
OCM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,859,718 - 5,886,363 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,879,827 - 5,886,363 (+)Ensemblhg38GRCh38
GRCh3775,899,349 - 5,925,994 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,886,955 - 5,892,520 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34797,258,662 - 97,264,067NCBI
Celera75,879,996 - 5,885,563 (+)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,831,808 - 5,837,381 (+)NCBIHuRef
CHM1_175,919,985 - 5,925,547 (+)NCBICHM1_1
T2T-CHM13v2.075,977,469 - 6,004,117 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,966,774 - 5,972,339 (+)NCBI
Ocm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395143,956,615 - 143,987,691 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5143,956,622 - 143,963,488 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm39 Ensembl5143,970,125 - 143,987,459 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385144,019,807 - 144,050,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5144,019,804 - 144,026,670 (-)Ensemblmm10GRCm38
MGSCv375144,780,676 - 144,811,478 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365144,273,334 - 144,304,136 (-)NCBIMGSCv36mm8
Celera5141,002,113 - 141,033,119 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map582.85NCBI
Ocm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546013,876,279 - 13,880,643 (-)Ensembl
ChiLan1.0NW_00495546013,876,279 - 13,880,643 (-)NCBIChiLan1.0ChiLan1.0
OCM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,775,792 - 10,826,576 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1759,100,497 - 59,151,284 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v076,066,257 - 6,126,400 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.176,089,803 - 6,114,752 (+)NCBIPanPan1.1PanPan1.1panPan2
OCM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.135,239,438 - 5,245,329 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.235,300,189 - 5,306,245 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ocm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474031,461,266 - 31,465,473 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474031,461,152 - 31,581,141 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ocm
356 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:174
Count of miRNA genes:126
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000043439
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)121186960016966542Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 4 8 94 44 50 21 26 21 6 107 45 82 21 82 29 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000043439   ⟹   ENSRNOP00000040755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1212,628,551 - 12,634,465 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092601   ⟹   ENSRNOP00000075788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,676,520 - 15,710,375 (+)Ensembl
mRatBN7.2 Ensembl1210,586,897 - 10,596,707 (+)Ensembl
Rnor_6.0 Ensembl1212,624,723 - 12,634,472 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135538   ⟹   ENSRNOP00000110303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,686,944 - 15,710,375 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000163523   ⟹   ENSRNOP00000105909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,704,573 - 15,710,379 (+)Ensembl
RefSeq Acc Id: NM_012995   ⟹   NP_037127
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,700,626 - 15,710,375 (+)NCBI
mRatBN7.21210,586,956 - 10,596,705 (+)NCBI
Dahl_SR_JrHsd1217,179,711 - 17,189,322 (+)NCBI
Lyon_Normotensive1217,105,849 - 17,115,462 (+)NCBI
Lyon_Hypertensive1215,956,885 - 15,966,494 (+)NCBI
F344_StmMcwi1226,538,272 - 26,547,520 (+)NCBI
Rnor_6.01212,624,723 - 12,634,472 (+)NCBI
Rnor_5.01214,619,319 - 14,678,847 (+)NCBI
RGSC_v3.41210,916,095 - 10,925,595 (+)RGD
Celera1212,384,375 - 12,394,039 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248852   ⟹   XP_006248914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,687,066 - 15,710,373 (+)NCBI
mRatBN7.21210,573,391 - 10,596,703 (+)NCBI
Rnor_6.01212,611,121 - 12,634,470 (+)NCBI
Rnor_5.01214,619,319 - 14,678,847 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063271083   ⟹   XP_063127153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,649,453 - 15,710,373 (+)NCBI
RefSeq Acc Id: XM_063271084   ⟹   XP_063127154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,649,452 - 15,710,373 (+)NCBI
RefSeq Acc Id: XM_063271085   ⟹   XP_063127155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,687,073 - 15,710,373 (+)NCBI
RefSeq Acc Id: NP_037127   ⟸   NM_012995
- UniProtKB: P02631 (UniProtKB/Swiss-Prot),   A6K1I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248914   ⟸   XM_006248852
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000040755   ⟸   ENSRNOT00000043439
Ensembl Acc Id: ENSRNOP00000075788   ⟸   ENSRNOT00000092601
RefSeq Acc Id: XP_063127154   ⟸   XM_063271084
- Peptide Label: isoform X2
- UniProtKB: P02631 (UniProtKB/Swiss-Prot),   A6K1I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127153   ⟸   XM_063271083
- Peptide Label: isoform X2
- UniProtKB: P02631 (UniProtKB/Swiss-Prot),   A6K1I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127155   ⟸   XM_063271085
- Peptide Label: isoform X2
- UniProtKB: P02631 (UniProtKB/Swiss-Prot),   A6K1I3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105909   ⟸   ENSRNOT00000163523
Ensembl Acc Id: ENSRNOP00000110303   ⟸   ENSRNOT00000135538
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P02631-F1-model_v2 AlphaFold P02631 1-109 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698429
Promoter ID:EPDNEW_R8954
Type:single initiation site
Name:Ocm2_1
Description:oncomodulin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01212,624,695 - 12,624,755EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3222 AgrOrtholog
BioCyc Gene G2FUF-20029 BioCyc
Ensembl Genes ENSRNOG00000001031 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000092601 ENTREZGENE
  ENSRNOT00000092601.2 UniProtKB/Swiss-Prot
  ENSRNOT00000135538 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Parvalbumin UniProtKB/Swiss-Prot
KEGG Report rno:25503 UniProtKB/Swiss-Prot
NCBI Gene 25503 ENTREZGENE
PANTHER ONCOMODULIN-2-RELATED UniProtKB/Swiss-Prot
  PTHR11653 UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Ocm PhenoGen
PRINTS PARVALBUMIN UniProtKB/Swiss-Prot
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001031 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0ABK0LJK9_RAT UniProtKB/TrEMBL
  A0ABK0M5D9_RAT UniProtKB/TrEMBL
  A6K1I3 ENTREZGENE, UniProtKB/TrEMBL
  ONCO_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-05 Ocm  oncomodulin  Ocm2  oncomodulin 2  Name and Symbol changed 629549 APPROVED
2013-02-27 Ocm2  oncomodulin 2  Ocm  oncomodulin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Ocm  Oncomodulin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease expression activated in many tumors 729147
gene_expression expressed only in extra-embryonic tissues such as the placenta 729147