Mst1 (macrophage stimulating 1) - Rat Genome Database

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Gene: Mst1 (macrophage stimulating 1) Rattus norvegicus
Analyze
Symbol: Mst1
Name: macrophage stimulating 1
RGD ID: 3114
Description: Enables enzyme binding activity and histone kinase activity. Involved in several processes, including cellular response to hypoxia; cellular response to type II interferon; and flagellated sperm motility. Predicted to be located in vacuole. Predicted to be active in extracellular space. Orthologous to several human genes including MST1 (macrophage stimulating 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D8h3f15s2; E2F transcription factor 2; E2F2; hepatocyte growth factor-like protein; Macrophage stimulating 1 (hepatocyte growth factor-like)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,646,485 - 117,652,016 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8117,647,438 - 117,652,015 (+)EnsemblGRCr8
mRatBN7.28108,767,886 - 108,773,425 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,768,839 - 108,773,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,395,059 - 114,399,629 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,594,383 - 112,598,953 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,437,023 - 110,441,594 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,857,716 - 116,862,286 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,857,684 - 116,862,423 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,211,755 - 116,216,379 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,348,203 - 113,352,773 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,073,056 - 108,077,626 (+)NCBICelera
RGSC_v3.18113,367,657 - 113,372,228 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-naphthylamine  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
entinostat  (ISO)
ethanol  (ISO)
Evodiamine  (ISO)
furan  (EXP)
L-ascorbic acid  (ISO)
lipopolysaccharide  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
prothioconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulforaphane  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
XMU-MP-1  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Molecular cloning of rat macrophage-stimulating protein and its involvement in the male reproductive system. Ohshiro K, etal., Biochem Biophys Res Commun 1996 Oct 3;227(1):273-80.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Protein-L-isoaspartate (D-aspartate) O-methyltransferase protects cardiomyocytes against hypoxia induced apoptosis through inhibiting proapoptotic kinase Mst1. Yan G, etal., Int J Cardiol. 2013 Oct 9;168(4):3291-9. doi: 10.1016/j.ijcard.2013.04.045. Epub 2013 May 3.
10. Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling. Yun HJ, etal., EMBO J. 2011 May 13;30(12):2465-76. doi: 10.1038/emboj.2011.152.
Additional References at PubMed
PMID:7508914   PMID:12477932   PMID:12606483   PMID:15961701   PMID:17102628   PMID:17409315   PMID:18986304   PMID:19221179   PMID:19720831   PMID:20921231   PMID:22087277   PMID:23376485  
PMID:23527007   PMID:25049204   PMID:25277788   PMID:26464622   PMID:30048231   PMID:32240614   PMID:33568044   PMID:34217161   PMID:38265688  


Genomics

Comparative Map Data
Mst1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,646,485 - 117,652,016 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8117,647,438 - 117,652,015 (+)EnsemblGRCr8
mRatBN7.28108,767,886 - 108,773,425 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,768,839 - 108,773,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,395,059 - 114,399,629 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,594,383 - 112,598,953 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,437,023 - 110,441,594 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,857,716 - 116,862,286 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,857,684 - 116,862,423 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,211,755 - 116,216,379 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,348,203 - 113,352,773 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,073,056 - 108,077,626 (+)NCBICelera
RGSC_v3.18113,367,657 - 113,372,228 (+)NCBI
Cytogenetic Map8q32NCBI
MST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,683,947 - 49,689,474 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl349,683,947 - 49,689,501 (-)Ensemblhg38GRCh38
GRCh37349,721,380 - 49,726,907 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,696,391 - 49,701,099 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34349,696,391 - 49,701,099NCBI
Celera349,686,072 - 49,690,887 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef349,780,360 - 49,785,175 (-)NCBIHuRef
CHM1_1349,673,436 - 49,678,251 (-)NCBICHM1_1
T2T-CHM13v2.0349,713,231 - 49,718,759 (-)NCBIT2T-CHM13v2.0
Mst1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,957,607 - 107,962,226 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,957,635 - 107,962,202 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389108,080,409 - 108,085,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,080,436 - 108,085,003 (+)Ensemblmm10GRCm38
MGSCv379107,982,767 - 107,987,358 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369107,938,552 - 107,943,099 (+)NCBIMGSCv36mm8
Celera9107,690,205 - 107,694,796 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map959.07NCBI
Mst1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,590,755 - 1,595,148 (-)Ensembl
ChiLan1.0NW_0049555321,590,685 - 1,595,655 (-)NCBIChiLan1.0ChiLan1.0
MST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2249,670,785 - 49,676,364 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1349,675,558 - 49,681,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0349,616,339 - 49,621,749 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1350,855,283 - 50,856,052 (-)NCBIPanPan1.1PanPan1.1panPan2
MST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,582,237 - 39,586,958 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,582,282 - 39,586,908 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2039,503,160 - 39,507,883 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02039,939,767 - 39,944,483 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,938,823 - 39,944,461 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,306,836 - 39,311,565 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,710,205 - 39,714,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02039,990,036 - 39,994,752 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mst1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,538,735 - 64,545,696 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,299,300 - 1,303,959 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,298,853 - 1,306,088 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,214,937 - 32,219,902 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11332,214,934 - 32,220,045 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,394,134 - 35,399,843 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,078,662 - 11,083,885 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,074,114 - 11,083,368 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041155,916,564 - 155,921,896 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mst1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,610,241 - 3,617,530 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247303,612,467 - 3,617,257 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mst1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1899,409,868 - 99,414,439 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mst1
33 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:45
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000026711
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8111249511117802327Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 12 58 108 91 90 59 67 59 6 302 158 11 84 66 89 31 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000026711   ⟹   ENSRNOP00000026711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8117,647,438 - 117,652,015 (+)Ensembl
mRatBN7.2 Ensembl8108,768,839 - 108,773,416 (+)Ensembl
Rnor_6.0 Ensembl8116,857,684 - 116,862,423 (+)Ensembl
RefSeq Acc Id: NM_024352   ⟹   NP_077328
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88117,647,442 - 117,652,012 (+)NCBI
mRatBN7.28108,768,843 - 108,773,413 (+)NCBI
Rnor_6.08116,857,716 - 116,862,286 (+)NCBI
Rnor_5.08116,211,755 - 116,216,379 (+)NCBI
RGSC_v3.48113,348,203 - 113,352,773 (+)RGD
Celera8108,073,056 - 108,077,626 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080801   ⟹   XP_038936729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88117,646,929 - 117,652,016 (+)NCBI
mRatBN7.28108,768,326 - 108,773,425 (+)NCBI
RefSeq Acc Id: XM_039080802   ⟹   XP_038936730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88117,646,485 - 117,652,016 (+)NCBI
mRatBN7.28108,767,886 - 108,773,425 (+)NCBI
Protein Sequences
Protein RefSeqs NP_077328 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936729 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89796 (Get FASTA)   NCBI Sequence Viewer  
  CAA64473 (Get FASTA)   NCBI Sequence Viewer  
  EDL77193 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026711
  ENSRNOP00000026711.5
RefSeq Acc Id: NP_077328   ⟸   NM_024352
- Peptide Label: precursor
- UniProtKB: P70521 (UniProtKB/TrEMBL),   Q5EBC6 (UniProtKB/TrEMBL),   F7FMS0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026711   ⟸   ENSRNOT00000026711
RefSeq Acc Id: XP_038936730   ⟸   XM_039080802
- Peptide Label: isoform X2
- UniProtKB: F7FMS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936729   ⟸   XM_039080801
- Peptide Label: isoform X1
- UniProtKB: F7FMS0 (UniProtKB/TrEMBL)
Protein Domains
Apple   Kringle   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7FMS0-F1-model_v2 AlphaFold F7FMS0 1-739 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696289
Promoter ID:EPDNEW_R6814
Type:multiple initiation site
Name:Mst1_1
Description:macrophage stimulating 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08116,857,703 - 116,857,763EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3114 AgrOrtholog
BioCyc Gene G2FUF-29158 BioCyc
Ensembl Genes ENSRNOG00000019680 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026711 ENTREZGENE
  ENSRNOT00000026711.9 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  2.40.20.10 UniProtKB/TrEMBL
  Hepatocyte Growth Factor UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7322260 IMAGE-MGC_LOAD
InterPro HGF_MST1 UniProtKB/TrEMBL
  Kringle UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Kringle_CS UniProtKB/TrEMBL
  Kringle_sf UniProtKB/TrEMBL
  MSP_HGFL UniProtKB/TrEMBL
  Pan_app UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1_S6 UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Ser/Cys_Pept_Trypsin-like UniProtKB/TrEMBL
  Serine_protease_kringle UniProtKB/TrEMBL
KEGG Report rno:24566 UniProtKB/TrEMBL
MGC_CLONE MGC:108677 IMAGE-MGC_LOAD
NCBI Gene 24566 ENTREZGENE
PANTHER KRINGLE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PLASMINOGEN-RELATED UniProtKB/TrEMBL
Pfam Kringle UniProtKB/TrEMBL
  PAN_1 UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PhenoGen Mst1 PhenoGen
PIRSF HGF_MST1 UniProtKB/TrEMBL
  MSP_HGFL UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
  KRINGLE UniProtKB/TrEMBL
PROSITE KRINGLE_1 UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/TrEMBL
  PAN UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019680 RatGTEx
SMART PAN_AP UniProtKB/TrEMBL
  SM00130 UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP Hairpin loop containing domain-like UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Pept_Ser_Cys UniProtKB/TrEMBL
UniProt F7FMS0 ENTREZGENE, UniProtKB/TrEMBL
  P70521 ENTREZGENE, UniProtKB/TrEMBL
  Q5EBC6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-04 Mst1  macrophage stimulating 1  Mst1  Macrophage stimulating 1 (hepatocyte growth factor-like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Mst1  Macrophage stimulating 1 (hepatocyte growth factor-like)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed in spermatogonia and spermatocytes in the testis and the epithelium lining the lumen of the epididymis 633226
gene_product member of the hepatocyte growth factor family 633226