Mc5r (melanocortin 5 receptor) - Rat Genome Database

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Gene: Mc5r (melanocortin 5 receptor) Rattus norvegicus
Analyze
Symbol: Mc5r
Name: melanocortin 5 receptor
RGD ID: 3058
Description: Enables hormone binding activity and melanocortin receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human MC5R (melanocortin 5 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; melanocortin system pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MC5-R; melanocortin receptor 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81864,185,013 - 64,190,054 (+)NCBIGRCr8
mRatBN7.21861,915,188 - 61,920,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1861,915,188 - 61,920,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1863,990,228 - 63,995,268 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01864,695,178 - 64,700,218 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01862,539,890 - 62,544,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01864,113,659 - 64,118,700 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1864,114,933 - 64,116,524 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01863,329,399 - 63,330,432 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41864,679,384 - 64,680,417 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11864,752,231 - 64,753,823 (-)NCBI
Celera1860,019,520 - 60,020,553 (+)NCBICelera
RH 3.4 Map18628.5RGD
RH 3.4 Map18628.4RGD
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRatAcute-Phase Reaction  IEP 6484138mRNA:increased expression:liver (rat)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRatchromosome 18p deletion syndrome  ISOMC5R (Homo sapiens)8554872ClinVar Annotator: match by term: Del(18p) syndromeClinVarPMID:31690835
Mc5rRatintellectual disability  ISOMC5R (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 

1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRat1,2-dimethylhydrazine multiple interactionsEXP 6480464[APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of MC5R mRNACTDPMID:27840820
Mc5rRat1H-indole affects bindingISOMC5R (Homo sapiens)6480464indole analog binds to MC5R proteinCTDPMID:11909711
Mc5rRat2,3,7,8-tetrachlorodibenzodioxine increases metabolic processingEXP 6480464Tetrachlorodibenzodioxin results in increased metabolism of MC5R geneCTDPMID:32277265
Mc5rRat2-palmitoylglycerol increases expressionISOMC5R (Homo sapiens)64804642-palmitoylglycerol results in increased expression of MC5R mRNACTDPMID:37199045
Mc5rRat4-hydroxyphenyl retinamide decreases expressionISOMc5r (Mus musculus)6480464Fenretinide results in decreased expression of MC5R mRNACTDPMID:28973697
Mc5rRataflatoxin B1 decreases methylationISOMC5R (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of MC5R geneCTDPMID:27153756
Mc5rRatalpha-Zearalanol decreases expressionEXP 6480464Zeranol results in decreased expression of MC5R mRNACTDPMID:35163327
Mc5rRatalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MC5R mRNACTDPMID:35163327
Mc5rRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of MC5R mRNACTDPMID:16483693
Mc5rRatbenzo[a]pyrene increases methylationISOMC5R (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of MC5R exon and Benzo(a)pyrene results in increased methylation of MC5R promoterCTDPMID:27901495
Mc5rRatbis(2-chloroethyl) sulfide decreases expressionISOMc5r (Mus musculus)6480464Mustard Gas results in decreased expression of MC5R mRNACTDPMID:15674843
Mc5rRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of MC5R mRNACTDPMID:25181051
Mc5rRatbisphenol A decreases methylationISOMC5R (Homo sapiens)6480464bisphenol A results in decreased methylation of MC5R geneCTDPMID:31601247
Mc5rRatCGP 52608 multiple interactionsISOMC5R (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to MC5R gene]CTDPMID:28238834
Mc5rRatclofibrate decreases expressionISOMc5r (Mus musculus)6480464Clofibrate results in decreased expression of MC5R mRNACTDPMID:17585979
Mc5rRatdecabromodiphenyl ether increases expressionEXP 6480464decabromobiphenyl ether results in increased expression of MC5R mRNACTDPMID:23640034
Mc5rRatdexamethasone increases expressionEXP 6480464Dexamethasone results in increased expression of MC5R mRNACTDPMID:20032058
Mc5rRatdexamethasone multiple interactionsEXP 6480464Testosterone inhibits the reaction [Dexamethasone results in increased expression of MC5R mRNA]CTDPMID:20032058
Mc5rRatflavonoids increases expressionEXP 6480464Flavonoids results in increased expression of MC5R mRNACTDPMID:18035473
Mc5rRatgentamycin decreases expressionEXP 6480464Gentamicins results in decreased expression of MC5R mRNACTDPMID:22061828

1 to 20 of 34 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRatadenylate cyclase-activating G protein-coupled receptor signaling pathway involved_inISOMC5R (Homo sapiens)1624291 PMID:19329486RGDPMID:19329486
Mc5rRatadenylate cyclase-activating G protein-coupled receptor signaling pathway involved_inIBAMGI:1333809 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mc5rRatadenylate cyclase-activating G protein-coupled receptor signaling pathway involved_inIEAUniProtKB:P33032 and ensembl:ENSP000004680861600115GO_REF:0000107EnsemblGO_REF:0000107
Mc5rRatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mc5rRatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Mc5rRatregulation of metabolic process involved_inIBAMGI:101908 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mc5rRatsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRatcytoplasm is_active_inIBAMGI:104615 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mc5rRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Mc5rRatmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mc5rRatplasma membrane located_inIEAUniProtKB:P33032 and ensembl:ENSP000004680861600115GO_REF:0000107EnsemblGO_REF:0000107
Mc5rRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Mc5rRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Mc5rRatplasma membrane is_active_inIBAMGI:104615 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mc5rRatplasma membrane located_inISOMC5R (Homo sapiens)1624291 RGDGO_REF:0000052

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mc5rRatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Mc5rRatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Mc5rRathormone binding  IDA 729030 RGD 
Mc5rRathormone binding  IMP 1626221 RGD 
Mc5rRatmelanocortin receptor activity  IDA 729030 RGD 
Mc5rRatmelanocortin receptor activity enablesIEAInterPro:IPR000621 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Mc5rRatmelanocortin receptor activity enablesIBAPANTHER:PTN002733773 and Mc5r (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Mc5rRatmelanocortin receptor activity enablesIEAARBA:ARBA000292541600115GO_REF:0000117UniProtGO_REF:0000117
Mc5rRatmelanocortin receptor activity  IMP 1626221 RGD 
Mc5rRatprotein binding enablesISOMC5R (Homo sapiens)1624291UniProtKB:Q8TCY5 more ...RGDPMID:19329486
1 to 10 of 10 rows

RGD Manual Annotations


  

1 to 14 of 14 rows
#
Reference Title
Reference Citation
1. Binding of alpha-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway. Buggy JJ Biochem J. 1998 Apr 1;331 ( Pt 1):211-6.
2. The melanocortin system in control of inflammation. Catania A, etal., ScientificWorldJournal. 2010 Sep 14;10:1840-53.
3. Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Quebec Family Study. Chagnon YC, etal., Mol Med. 1997 Oct;3(10):663-73.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Molecular cloning and characterization of the rat fifth melanocortin receptor. Griffon N, etal., Biochem Biophys Res Commun 1994 Apr 29;200(2):1007-14.
7. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
8. Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response. Malik IA, etal., Histochem Cell Biol. 2012 Mar;137(3):279-91. Epub 2011 Dec 20.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Evidence for a stimulatory action of melanin-concentrating hormone on luteinising hormone release involving MCH1 and melanocortin-5 receptors. Murray JF, etal., J Neuroendocrinol. 2006 Mar;18(3):157-67.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
1 to 14 of 14 rows
PMID:14660008   PMID:17531155   PMID:19329486   PMID:22643233  



Mc5r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81864,185,013 - 64,190,054 (+)NCBIGRCr8
mRatBN7.21861,915,188 - 61,920,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1861,915,188 - 61,920,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1863,990,228 - 63,995,268 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01864,695,178 - 64,700,218 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01862,539,890 - 62,544,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01864,113,659 - 64,118,700 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1864,114,933 - 64,116,524 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01863,329,399 - 63,330,432 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41864,679,384 - 64,680,417 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11864,752,231 - 64,753,823 (-)NCBI
Celera1860,019,520 - 60,020,553 (+)NCBICelera
RH 3.4 Map18628.5RGD
RH 3.4 Map18628.4RGD
Cytogenetic Map18q12.1NCBI
MC5R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381813,824,149 - 13,827,323 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1813,824,149 - 13,827,323 (+)EnsemblGRCh38hg38GRCh38
GRCh371813,824,148 - 13,827,322 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361813,815,765 - 13,816,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 341813,815,764 - 13,816,742NCBI
Celera1813,706,729 - 13,708,047 (+)NCBICelera
Cytogenetic Map18p11.21NCBI
HuRef1813,778,780 - 13,780,099 (+)NCBIHuRef
CHM1_11813,824,630 - 13,825,948 (+)NCBICHM1_1
T2T-CHM13v2.01813,986,528 - 13,989,701 (+)NCBIT2T-CHM13v2.0
Mc5r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391868,469,811 - 68,475,517 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1868,470,575 - 68,475,517 (+)EnsemblGRCm39 Ensembl
GRCm381868,336,744 - 68,342,446 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1868,337,596 - 68,342,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv371868,497,257 - 68,499,365 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361868,462,972 - 68,465,092 (+)NCBIMGSCv36mm8
Celera1869,645,563 - 69,647,671 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1841.46NCBI
Mc5r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955402283,388 - 286,884 (-)NCBIChiLan1.0ChiLan1.0
MC5R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21724,217,275 - 24,222,385 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,907,321 - 9,914,981 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018495,561 - 501,555 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1182,668,281 - 2,669,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl182,668,394 - 2,669,371 (-)Ensemblpanpan1.1panPan2
MC5R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,429,331 - 24,433,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,410,285 - 25,414,162 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,326,030 - 24,331,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,328,811 - 24,329,788 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,381,249 - 24,385,125 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0124,267,632 - 24,271,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,538,879 - 24,544,347 (-)NCBIUU_Cfam_GSD_1.0
Mc5r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049443,972,966 - 3,976,952 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366263,202,346 - 3,204,477 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366263,203,437 - 3,204,743 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MC5R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl696,322,422 - 96,323,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1696,322,276 - 96,323,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2689,672,688 - 89,674,974 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MC5R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11872,263,016 - 72,268,436 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1872,264,815 - 72,265,792 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605047,330,875 - 47,334,183 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Mc5r
22 total Variants

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:103
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000022364
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 54 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185253986365844950Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)185880568763636873Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat

1 to 10 of 54 rows
RH142200  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21861,916,479 - 61,916,660 (+)MAPPERmRatBN7.2
Rnor_6.01864,114,951 - 64,115,131NCBIRnor6.0
Rnor_5.01863,329,212 - 63,329,392UniSTSRnor5.0
RGSC_v3.41864,680,424 - 64,680,604UniSTSRGSC3.4
Celera1860,019,333 - 60,019,513UniSTS
RH 3.4 Map18628.5UniSTS
Cytogenetic Map18q12.1UniSTS
RH94550  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21861,917,854 - 61,918,026 (+)MAPPERmRatBN7.2
Rnor_6.01864,116,326 - 64,116,497NCBIRnor6.0
Rnor_5.01863,330,587 - 63,330,758UniSTSRnor5.0
RGSC_v3.41864,679,058 - 64,679,229UniSTSRGSC3.4
Celera1860,020,708 - 60,020,879UniSTS
Cytogenetic Map18q12.1UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 11 8 69 63 62 33 18 33 6 101 49 49 5 38 29



Ensembl Acc Id: ENSRNOT00000022364   ⟹   ENSRNOP00000022364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1861,915,188 - 61,920,229 (+)Ensembl
Rnor_6.0 Ensembl1864,114,933 - 64,116,524 (+)Ensembl
RefSeq Acc Id: NM_013182   ⟹   NP_037314
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81864,185,013 - 64,190,054 (+)NCBI
mRatBN7.21861,915,188 - 61,920,229 (+)NCBI
Rnor_6.01864,115,138 - 64,116,171 (+)NCBI
Rnor_5.01863,329,399 - 63,330,432 (+)NCBI
RGSC_v3.41864,679,384 - 64,680,417 (-)RGD
Celera1860,019,520 - 60,020,553 (+)RGD
Sequence:
Protein RefSeqs NP_037314 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41577 (Get FASTA)   NCBI Sequence Viewer  
  EDM14757 (Get FASTA)   NCBI Sequence Viewer  
  EDM14758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022364
  ENSRNOP00000022364.3
GenBank Protein P35345 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037314   ⟸   NM_013182
- UniProtKB: P35345 (UniProtKB/Swiss-Prot),   A6IXX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022364   ⟸   ENSRNOT00000022364
Name Modeler Protein Id AA Range Protein Structure
AF-P35345-F1-model_v2 AlphaFold P35345 1-325 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-7103 BioCyc
Ensembl Genes ENSRNOG00000016685 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022364 ENTREZGENE
  ENSRNOT00000022364.5 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Melancort_rcpt UniProtKB/Swiss-Prot
  Melancort_rcpt_5 UniProtKB/Swiss-Prot
  Melcrt_ACTH_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:25726 UniProtKB/Swiss-Prot
NCBI Gene 25726 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Mc5r PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  MCRFAMILY UniProtKB/Swiss-Prot
  MELNOCORTINR UniProtKB/Swiss-Prot
  MELNOCORTN5R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016685 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A6IXX6 ENTREZGENE, UniProtKB/TrEMBL
  MC5R_RAT UniProtKB/Swiss-Prot, ENTREZGENE
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Mc5r  Melanocortin 5 receptor      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_process causes an increase in cAMP accumulation 729030
gene_protein 325 amino acids 729030