MC5R (melanocortin 5 receptor) - Rat Genome Database

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Pathways
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Gene: MC5R (melanocortin 5 receptor) Pan paniscus
Analyze
Symbol: MC5R
Name: melanocortin 5 receptor
RGD ID: 12025504
Description: ENCODES a protein that exhibits hormone binding (ortholog); melanocortin receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); regulation of metabolic process (inferred); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; melanocortin system pathway; ASSOCIATED WITH Acute-Phase Reaction (ortholog); chromosome 18p deletion syndrome (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: melanocortin receptor 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21724,217,275 - 24,222,385 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,907,321 - 9,914,981 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018495,561 - 501,555 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1182,668,281 - 2,669,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl182,668,394 - 2,669,371 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MC5R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21724,217,275 - 24,222,385 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,907,321 - 9,914,981 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018495,561 - 501,555 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1182,668,281 - 2,669,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl182,668,394 - 2,669,371 (-)Ensemblpanpan1.1panPan2
MC5R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381813,824,149 - 13,827,323 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1813,824,149 - 13,827,323 (+)EnsemblGRCh38hg38GRCh38
GRCh371813,824,148 - 13,827,322 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361813,815,765 - 13,816,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 341813,815,764 - 13,816,742NCBI
Celera1813,706,729 - 13,708,047 (+)NCBICelera
Cytogenetic Map18p11.21NCBI
HuRef1813,778,780 - 13,780,099 (+)NCBIHuRef
CHM1_11813,824,630 - 13,825,948 (+)NCBICHM1_1
T2T-CHM13v2.01813,986,528 - 13,989,701 (+)NCBIT2T-CHM13v2.0
Mc5r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391868,469,811 - 68,475,517 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1868,470,575 - 68,475,517 (+)EnsemblGRCm39 Ensembl
GRCm381868,336,744 - 68,342,446 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1868,337,596 - 68,342,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv371868,497,257 - 68,499,365 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361868,462,972 - 68,465,092 (+)NCBIMGSCv36mm8
Celera1869,645,563 - 69,647,671 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1841.46NCBI
Mc5r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81864,185,013 - 64,190,054 (+)NCBIGRCr8
mRatBN7.21861,915,188 - 61,920,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1861,915,188 - 61,920,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1863,990,228 - 63,995,268 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01864,695,178 - 64,700,218 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01862,539,890 - 62,544,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01864,113,659 - 64,118,700 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1864,114,933 - 64,116,524 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01863,329,399 - 63,330,432 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41864,679,384 - 64,680,417 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11864,752,231 - 64,753,823 (-)NCBI
Celera1860,019,520 - 60,020,553 (+)NCBICelera
RH 3.4 Map18628.5RGD
RH 3.4 Map18628.4RGD
Cytogenetic Map18q12.1NCBI
Mc5r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955402283,388 - 286,884 (-)NCBIChiLan1.0ChiLan1.0
MC5R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,429,331 - 24,433,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha125,410,285 - 25,414,162 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,326,030 - 24,331,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,328,811 - 24,329,788 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,381,249 - 24,385,125 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0124,267,632 - 24,271,507 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,538,879 - 24,544,347 (-)NCBIUU_Cfam_GSD_1.0
Mc5r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049443,972,966 - 3,976,952 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366263,202,346 - 3,204,477 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366263,203,437 - 3,204,743 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MC5R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl696,322,422 - 96,323,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1696,322,276 - 96,323,795 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2689,672,688 - 89,674,974 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MC5R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11872,263,016 - 72,268,436 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1872,264,815 - 72,265,792 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605047,330,875 - 47,334,183 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034943554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000002292   ⟹   ENSPPAP00000000552
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl182,668,394 - 2,669,371 (-)Ensembl
RefSeq Acc Id: XM_034943554   ⟹   XP_034799445
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21724,217,275 - 24,222,385 (-)NCBI
NHGRI_mPanPan1189,907,321 - 9,914,981 (-)NCBI
Mhudiblu_PPA_v018495,561 - 501,555 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034799445 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000000552.1
Reference Protein Sequences
RefSeq Acc Id: XP_034799445   ⟸   XM_034943554
- UniProtKB: A0A2R8Z6X1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000000552   ⟸   ENSPPAT00000002292
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000002115 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000002292.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Melancort_rcpt UniProtKB/TrEMBL
  Melancort_rcpt_5 UniProtKB/TrEMBL
  Melcrt_ACTH_rcpt UniProtKB/TrEMBL
NCBI Gene MC5R ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PTHR22750:SF5 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  MCRFAMILY UniProtKB/TrEMBL
  MELNOCORTINR UniProtKB/TrEMBL
  MELNOCORTN5R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R8Z6X1 ENTREZGENE, UniProtKB/TrEMBL