Cd3d (CD3 delta subunit of T-cell receptor complex) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cd3d (CD3 delta subunit of T-cell receptor complex) Rattus norvegicus
Analyze
Symbol: Cd3d
Name: CD3 delta subunit of T-cell receptor complex
RGD ID: 2304
Description: Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and positive thymic T cell selection. Predicted to be located in plasma membrane. Predicted to be part of alpha-beta T cell receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 19 and severe combined immunodeficiency. Orthologous to human CD3D (CD3 delta subunit of T-cell receptor complex); PARTICIPATES IN adaptive immune response pathway; interleukin-12 signaling pathway; Chagas disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CD3 antigen delta polypeptide; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3d molecule; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,184,573 - 54,190,112 (+)NCBIGRCr8
mRatBN7.2845,287,803 - 45,293,342 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,288,749 - 45,301,809 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,784,363 - 50,788,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,063,089 - 49,067,694 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,933,645 - 46,938,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,282,502 - 49,287,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,282,460 - 49,287,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,900,331 - 47,905,113 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,932,151 - 47,936,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,940,916 - 47,945,510 (+)NCBI
Celera844,873,511 - 44,878,104 (+)NCBICelera
RH 3.4 Map8450.1RGD
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatsevere combined immunodeficiency  ISOCD3D (Homo sapiens)1549420 RGD 
1 to 16 of 16 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatCD3epsilon deficiency  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: CD3epsilon deficiencyClinVarPMID:14602880 more ...
Cd3dRatchromosome 11 partial duplication syndrome  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Distal trisomy 11qClinVarPMID:25741868
Cd3dRatDwarfism  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Short statureClinVarPMID:32581362
Cd3dRatFamilial Atrial Fibrillation 14  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Atrial fibrillation more ...ClinVarPMID:28492532
Cd3dRatgenetic disease  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Cd3dRatglycogen storage disease Ib  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Glucose-6-phosphate transport defectClinVarPMID:28492532
Cd3dRatimmunodeficiency 17  ISOCD3D (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14602880 more ...
Cd3dRatimmunodeficiency 18  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 18ClinVarPMID:14602880 more ...
Cd3dRatimmunodeficiency 19  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 19ClinVarPMID:10935641 more ...
Cd3dRatinflammatory bowel disease 28  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Inflammatory bowel disease 28ClinVarPMID:14602880 more ...
Cd3dRatintellectual disability  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Cd3dRatisolated microphthalmia 5  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Isolated microphthalmia 5ClinVarPMID:28492532
Cd3dRatlong QT syndrome 10  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndrome 10ClinVarPMID:28492532
Cd3dRatRASopathy  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: RASopathyClinVarPMID:28492532
Cd3dRatsevere combined immunodeficiency  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Severe combined immunodeficiency diseaseClinVarPMID:17576681 more ...
Cd3dRatsevere combined immunodeficiency 104  ISOCD3D (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 104ClinVarPMID:25741868 and PMID:28492532
1 to 16 of 16 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatallergic contact dermatitis  ISOCD3D (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17597826
Cd3dRatliver disease  ISOCD3D (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19784758
Cd3dRatprimary biliary cholangitis  ISOCD3D (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18422935
Cd3dRatsevere combined immunodeficiency  ISOCD3D (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15546002
Cd3dRattoxic encephalopathy  ISOCD3D (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19784758
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatimmunodeficiency 19  ISOCD3D (Homo sapiens)7240710 OMIM 

1 to 20 of 92 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRat1,2-dimethylhydrazine increases expressionISOCd3d (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CD3D mRNACTDPMID:22206623
Cd3dRat17alpha-ethynylestradiol decreases expressionISOCd3d (Mus musculus)6480464Ethinyl Estradiol results in decreased expression of CD3D mRNACTDPMID:17942748
Cd3dRat17alpha-ethynylestradiol affects expressionISOCd3d (Mus musculus)6480464Ethinyl Estradiol affects the expression of CD3D mRNACTDPMID:14976129 and PMID:17555576
Cd3dRat17alpha-ethynylestradiol multiple interactionsISOCd3d (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CD3D mRNACTDPMID:17942748
Cd3dRat17beta-estradiol decreases expressionISOCd3d (Mus musculus)6480464Estradiol results in decreased expression of CD3D mRNACTDPMID:19484750
Cd3dRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCd3d (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CD3D mRNACTDPMID:18343893
Cd3dRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of CD3D mRNACTDPMID:34747641
Cd3dRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCd3d (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of CD3D mRNACTDPMID:16611356 more ...
Cd3dRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCd3d (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CD3D mRNACTDPMID:17942748
Cd3dRat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOCd3d (Mus musculus)64804642 more ...CTDPMID:18343893
Cd3dRat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOCd3d (Mus musculus)64804642 more ...CTDPMID:38648751
Cd3dRat2,6-di-tert-butyl-4-methylphenol decreases expressionISOCd3d (Mus musculus)6480464Butylated Hydroxytoluene results in decreased expression of CD3D mRNACTDPMID:19925653
Cd3dRat3-methylcholanthrene decreases expressionISOCd3d (Mus musculus)6480464Methylcholanthrene results in decreased expression of CD3D mRNACTDPMID:25926378
Cd3dRat4,4'-diaminodiphenylmethane decreases expressionISOCd3d (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of CD3D mRNACTDPMID:18648102
Cd3dRat4-hydroxyphenyl retinamide decreases expressionISOCd3d (Mus musculus)6480464Fenretinide results in decreased expression of CD3D mRNACTDPMID:28973697
Cd3dRat7,12-dimethyltetraphene increases expressionEXP 64804649 more ...CTDPMID:19480007
Cd3dRatacetamide increases expressionEXP 6480464acetamide results in increased expression of CD3D mRNACTDPMID:31881176
Cd3dRataflatoxin B1 affects expressionISOCD3D (Homo sapiens)6480464Aflatoxin B1 affects the expression of CD3D proteinCTDPMID:20106945
Cd3dRataflatoxin B1 increases methylationISOCD3D (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of CD3D geneCTDPMID:27153756
Cd3dRataflatoxin B1 increases expressionISOCD3D (Homo sapiens)6480464Aflatoxin B1 results in increased expression of CD3D mRNACTDPMID:21632981 and PMID:22100608

1 to 20 of 92 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatadaptive immune response involved_inIEAUniProtKB-KW:KW-10641600115GO_REF:0000043UniProtGO_REF:0000043
Cd3dRatbiological_process  ND 159840703/2007: no relevant rat dataRGD 
Cd3dRatcell surface receptor signaling pathway involved_inIEAInterPro:IPR0031101600115GO_REF:0000002InterProGO_REF:0000002
Cd3dRatcell surface receptor signaling pathway involved_inIBAMGI:88332 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cd3dRatimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Cd3dRatpositive thymic T cell selection involved_inISSUniProtKB:P042351600115GO_REF:0000024UniProtGO_REF:0000024
Cd3dRatpositive thymic T cell selection involved_inIBAMGI:88331 and PANTHER:PTN0000602801600115GO_REF:0000033GO_CentralGO_REF:0000033
Cd3dRatpositive thymic T cell selection involved_inISOCd3d (Mus musculus)1624291 PMID:9135151RGDPMID:9135151

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatalpha-beta T cell receptor complex part_ofISOCD3D (Homo sapiens)1624291 PMID:31461748 and PMID:9485181RGDPMID:31461748 and PMID:9485181
Cd3dRatalpha-beta T cell receptor complex part_ofISOCd3d (Mus musculus)1624291 PMID:9208839RGDPMID:9208839
Cd3dRatalpha-beta T cell receptor complex part_ofIBAMGI:88331 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cd3dRatalpha-beta T cell receptor complex part_ofIEAARBA:ARBA000272781600115GO_REF:0000117UniProtGO_REF:0000117
Cd3dRatexternal side of plasma membrane is_active_inIBAMGI:88332 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cd3dRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Cd3dRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Cd3dRatmembrane located_inIEAInterPro:IPR0031101600115GO_REF:0000002InterProGO_REF:0000002
Cd3dRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Cd3dRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Cd3dRatplasma membrane located_inISOCD3D (Homo sapiens)1624291 PMID:31461748RGDPMID:31461748
Cd3dRatT cell receptor complex part_ofISOCD3D (Homo sapiens)1624291 PMID:8176201RGDPMID:8176201
1 to 12 of 12 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatadaptive immune response pathway  ISS 1549421 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatChagas disease pathway  IEA 6907045 KEGGrno:05142
Cd3dRatmeasles pathway  IEA 6907045 KEGGrno:05162
Cd3dRatprimary immunodeficiency pathway  IEA 6907045 KEGGrno:05340
Cd3dRatT cell receptor signaling pathway  IEA 6907045 KEGGrno:04660

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd3dRatinterleukin-12 signaling pathway  ISOCD3D (Homo sapiens)6484113 PIDPID:200045

1 to 17 of 17 rows
#
Reference Title
Reference Citation
1. Initiation of TCR signaling: regulation within CD3 dimers. Alarcon B, etal., Immunol Rev 2003 Feb;191:38-46.
2. Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency. Dadi HK, etal., N Engl J Med 2003 Nov 6;349(19):1821-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex. Pan Q, etal., J Biol Chem 2004 Dec 3;279(49):51068-74. Epub 2004 Sep 30.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
17. Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein. van den Elsen P, etal., Nature 1985 Apr 11-17;314(6011):542-4.
1 to 17 of 17 rows
PMID:2017177   PMID:2143819   PMID:2395634   PMID:8176201   PMID:9135151   PMID:9208839   PMID:9485181   PMID:14967045  



Cd3d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,184,573 - 54,190,112 (+)NCBIGRCr8
mRatBN7.2845,287,803 - 45,293,342 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,288,749 - 45,301,809 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,784,363 - 50,788,968 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,063,089 - 49,067,694 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,933,645 - 46,938,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,282,502 - 49,287,095 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,282,460 - 49,287,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,900,331 - 47,905,113 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,932,151 - 47,936,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,940,916 - 47,945,510 (+)NCBI
Celera844,873,511 - 44,878,104 (+)NCBICelera
RH 3.4 Map8450.1RGD
Cytogenetic Map8q22NCBI
CD3D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,338,954 - 118,342,705 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11118,334,537 - 118,342,705 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,209,669 - 118,213,420 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,714,999 - 117,718,669 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411117,710,474 - 117,718,533NCBI
Celera11115,367,658 - 115,371,328 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,143,683 - 114,147,356 (-)NCBIHuRef
CHM1_111118,096,225 - 118,099,892 (-)NCBICHM1_1
T2T-CHM13v2.011118,355,312 - 118,360,628 (-)NCBIT2T-CHM13v2.0
Cd3d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,893,067 - 44,898,350 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,893,084 - 44,898,637 (+)EnsemblGRCm39 Ensembl
GRCm38944,981,769 - 44,987,052 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,981,786 - 44,987,339 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,789,869 - 44,795,135 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,732,876 - 44,737,416 (+)NCBIMGSCv36mm8
Celera942,246,904 - 42,252,171 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Cd3d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,480,977 - 19,484,721 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,481,059 - 19,484,890 (-)NCBIChiLan1.0ChiLan1.0
LOC100979946
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,038,840 - 119,044,827 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,145,509 - 120,149,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,174,007 - 113,179,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,105,868 - 117,111,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,105,868 - 117,111,051 (-)Ensemblpanpan1.1panPan2
CD3D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,392,841 - 15,396,745 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,389,243 - 15,396,750 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,443,561 - 15,447,497 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,335,138 - 15,339,065 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,331,562 - 15,339,070 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,473,389 - 15,477,325 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,376,847 - 15,380,783 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,417,998 - 15,421,934 (+)NCBIUU_Cfam_GSD_1.0
Cd3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,478,720 - 100,482,225 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,399,845 - 3,403,634 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,400,129 - 3,403,628 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD3D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,637,129 - 45,644,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1945,640,475 - 45,644,153 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,681,602 - 50,685,279 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD3D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,715,148 - 109,719,576 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,713,017 - 109,719,950 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,315,112 - 16,320,264 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd3d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478413,733,403 - 13,737,356 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478413,733,465 - 13,754,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Cd3d
8 total Variants

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:23
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000021488
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 64 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat

1 to 10 of 64 rows
RH94582  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map8450.1UniSTS
Cytogenetic Map8q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 29 53 85 85 54 25 54 6 179 73 34 35 57 31



Ensembl Acc Id: ENSRNOT00000021488   ⟹   ENSRNOP00000021489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl845,288,749 - 45,301,809 (+)Ensembl
Rnor_6.0 Ensembl849,282,460 - 49,287,110 (+)Ensembl
RefSeq Acc Id: NM_013169   ⟹   NP_037301
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8854,185,519 - 54,190,112 (+)NCBI
mRatBN7.2845,288,749 - 45,293,342 (+)NCBI
Rnor_6.0849,282,502 - 49,287,095 (+)NCBI
Rnor_5.0847,900,331 - 47,905,113 (+)NCBI
RGSC_v3.4847,932,151 - 47,936,744 (+)RGD
Celera844,873,511 - 44,878,104 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080903   ⟹   XP_038936831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8854,184,573 - 54,190,109 (+)NCBI
mRatBN7.2845,287,803 - 45,293,335 (+)NCBI
Protein RefSeqs NP_037301 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936831 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA37521 (Get FASTA)   NCBI Sequence Viewer  
  EDL95345 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000101621
GenBank Protein P19377 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_037301   ⟸   NM_013169
- Peptide Label: precursor
- UniProtKB: P19377 (UniProtKB/Swiss-Prot),   A6J422 (UniProtKB/TrEMBL),   A0A8L2QB67 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021489   ⟸   ENSRNOT00000021488
RefSeq Acc Id: XP_038936831   ⟸   XM_039080903
- Peptide Label: isoform X1
Name Modeler Protein Id AA Range Protein Structure
AF-P19377-F1-model_v2 AlphaFold P19377 1-173 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695907
Promoter ID:EPDNEW_R6432
Type:initiation region
Name:Cd3d_1
Description:CD3d molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0849,282,502 - 49,282,562EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-30689 BioCyc
Ensembl Genes ENSRNOG00000015994 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000127768 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  YojJ-like UniProtKB/Swiss-Prot
InterPro CD3_esu/gsu/dsu UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_4 UniProtKB/Swiss-Prot
  Phos_immunorcpt_sig_ITAM UniProtKB/Swiss-Prot
KEGG Report rno:25710 UniProtKB/Swiss-Prot
NCBI Gene 25710 ENTREZGENE
PANTHER PTHR10570 UniProtKB/Swiss-Prot
  PTHR10570:SF5 UniProtKB/Swiss-Prot
Pfam Ig_4 UniProtKB/Swiss-Prot
  ITAM UniProtKB/Swiss-Prot
PhenoGen Cd3d PhenoGen
PROSITE ITAM_1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015994 RatGTEx
SMART ITAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
TIGR TC223607
UniProt A0A8L2QB67 ENTREZGENE, UniProtKB/TrEMBL
  A6J422 ENTREZGENE, UniProtKB/TrEMBL
  CD3D_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-14 Cd3d  CD3 delta subunit of T-cell receptor complex  Cd3d  CD3d molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-02 Cd3d  CD3d molecule  Cd3d  CD3 molecule, delta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Cd3d  CD3 molecule delta polypeptide  Cd3d  CD3 antigen delta polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Cd3d  CD3 antigen delta polypeptide      Symbol and Name status set to approved 70586 APPROVED

Note Type Note Reference
gene_function human homolog is a component of the antigen receptor on T cells 634716