Cacna1e Rat Gene (calcium channel, voltage-dependent, R type, alpha 1E subunit)

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Keyword

Gene:
Cacna1e ( Rattus norvegicus )
calcium channel, voltage-dependent, R type, alpha 1E subunit
Description: T-type low voltage-activated calcium channel that may be involved in neuronal firing
Synonyms: calcium channel, voltage-dependent, L type, alpha 1E subunit; CACHA1E;
ArrayIDs: 6389602; 5959197; 5895641; 6086084; 5821321; 5955517; 5810409; 5856211; 6366760; L15453_at; 6556446; 6066123; 6004300; 6641235; 6588677; 6621295; 1370586_a_at; 6489307; 6279645; 6591441; 6089712; 5896059; 6429414; 6114853; 6461408; 5755346; 6415673; 5695032; 5676921; A_44_P240646; 5958287; GE19619; 6559778; A_44_P236697; 6397063; 5798180; A_44_P545717; 5772533; 5716514; 5692190; 5850104; 6557893; 6640204; 6730199; 6366485; 6591824; 6725536; A_43_P22014; A_44_P297167; 5708233; 5633770; 5729335; 5757174; 6426268; 6119436; 5778662; 6570584; 6599024; 6623490; 6680787; 6612369; 5721757; 6687487; 6313331; 5917892; 5829382; 5725888;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: CACNA1E     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Cacna1e     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Cacna1e Rat Celera Assembly 13 66463539 - 66771452
RGSC genome assembly v3.4 13 69366863 - 69683895
Cytogenetic 13 q21
genome assembly 3.1 13 69380942 - 69697975
Mus musculus Cacna1e Mouse genome assembly build 36.1 1 156239649 - 156573050
Cytogenetic 1 1 G3
Homo sapiens CACNA1E human genome assembly 1 178184372 - 178502370
Human genome assembly build 36.2 1 179719339 - 180037339
Cytogenetic 1 q25-q31

View comparative maps:      NCBI MapViewer

Genome
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Browsers:

Annotation
Molecular Function

Note Reference

low voltage-activated calcium channel, T-type 69790

Gene Ontology

voltage-gated calcium channel activity,  low voltage-gated calcium channel activity,  voltage-gated ion channel activity ... (details...)
Biological Process

Note Reference

may be an important regulator of neuronal and muscle excitability, secretion, and possibly cell growth and differentiation 69790

Gene Ontology

transmembrane transport,  glucose homeostasis,  calcium ion transport ... (details...)
Cellular Component

Gene Ontology

voltage-gated calcium channel complex,  membrane,  integral to membrane ... (details...)
Disease

Ontology

Hyperglycemia (details...)
Expression

Note Reference

expressed in brain and atrial myocytes 69790

External Links
Databases
DATABASE ID SOURCE
PROSITE: EF_HAND_2 IPI
UNIPARC: UPI0000127278 IPI
UNIPARC: UPI0000180DAD IPI
KEGG Report: rno:54234 ENTREZGENE
HomoloGene Group ID: 20185 ENTREZGENE
Germonline: 2246
Pfam: Ion_trans IPI
Pfam: Ca_chan_IQ IPI
KEGG Pathway: 04930 ENTREZGENE
KEGG Pathway: 04010 ENTREZGENE
KEGG Pathway: 04020 ENTREZGENE
InterPro: EF_HAND_2. IPI
InterPro: VDCC_a1su_IQ. IPI
InterPro: VDCC_R_a1su. IPI
InterPro: VDCCAlpha1. IPI
InterPro: Ion_trans. IPI
IPI: IPI00198751 IPI
IPI: IPI00201157 IPI
Ensembl Protein: ENSRNOP00000003869 IPI
Ensembl Protein: ENSRNOP00000003928 IPI
Entrez Gene: Cacna1e ENTREZGENE
UniProt: Q71V43_RAT IPI
UniProt: CAC1E_RAT IPI
UniProt: Q9WTU8_RAT IPI
UniProt: Q923K6_RAT IPI
UniProt: O35781_RAT IPI
UniProt: Q9R1B4_RAT IPI
Ensembl Genes: ENSRNOG00000002863 IPI
PANTHER: RVDCCAlpha1 IPI
PRINTS: RVDCCALPHA1. IPI
PRINTS: CACHANNEL. IPI
Sequences
Nucleotide: CH473958 Get FASTA Search GEO Profiles
Nucleotide: AF033580 Get FASTA Search GEO Profiles
Nucleotide: AF057029 Get FASTA Search GEO Profiles
Nucleotide: NM_019294 Get FASTA Search GEO Profiles
Nucleotide: AY029412 Get FASTA Search GEO Profiles
Nucleotide: AF146634 Get FASTA Search GEO Profiles
Nucleotide: L15453 Get FASTA Search GEO Profiles
Nucleotide: AF009419 Get FASTA Search GEO Profiles
(View all 8 Nucleotide Accessions)
Protein: NP_062167 Get FASTA
Protein: AAD31924 Get FASTA
Protein: EDM09520 Get FASTA
Protein: EDM09521 Get FASTA
Protein: AAC53581 Get FASTA
Protein: AAB96650 Get FASTA
Protein: AAD23737 Get FASTA
Protein: AAK33009 Get FASTA
Protein: AAA40855 Get FASTA
Protein: O35781 Get FASTA
Protein: Q07652 Get FASTA
Protein: Q71V43 Get FASTA
Protein: Q923K6 Get FASTA
Protein: Q9R1B4 Get FASTA
Protein: Q9WTU8 Get FASTA
(View all 15 Protein Accessions)
Clusters
UniGene: 216370
UniGene: 214223
UniGene: 10742

References
Curated References
10 references in RGD related to Cacna1e

Other References
10 other references at PubMed related to Cacna1e

Database Information
RGD ID 2246
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

15-FEB-08: Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit Cacna1e calcium channel, voltage-dependent, L type, alpha 1E subunit APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

30-MAR-06: Cacna1e calcium channel, voltage-dependent, L type, alpha 1E subunit APPROVED Symbol and Name status set to approved 1299863

10-JUN-02: Cacna1e calcium channel, voltage-dependent, L type, alpha 1E subunit PROVISIONAL Name updated 70585