Atp2b2 (ATPase plasma membrane Ca2+ transporting 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Atp2b2 (ATPase plasma membrane Ca2+ transporting 2) Rattus norvegicus
Analyze
Symbol: Atp2b2
Name: ATPase plasma membrane Ca2+ transporting 2
RGD ID: 2176
Description: Enables several functions, including ATP binding activity; P-type calcium transporter activity; and PDZ domain binding activity. Involved in neural retina development. Located in apical plasma membrane; dendritic spine membrane; and neuronal cell body membrane. Is active in several cellular components, including GABA-ergic synapse; parallel fiber to Purkinje cell synapse; and synaptic membrane. Biomarker of brain infarction. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 82 and autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATPase isoform 2 Na+K+ transporting beta polypeptide 2; ATPase isoform 2, Na+K+ transporting, beta polypeptide 2; ATPase, Ca++ transporting, plasma membrane 2; plasma membrane Ca++-ATPase; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 2; PMCA2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,450,207 - 148,763,653 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)EnsemblGRCr8
mRatBN7.24146,894,602 - 147,208,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,896,332 - 147,140,665 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4152,279,141 - 152,592,499 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04148,060,008 - 148,373,376 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,688,239 - 147,002,829 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,704,779 - 145,948,997 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,703,046 - 146,016,325 (-)Ensemblrn6Rnor6.0
Rnor_5.04209,001,178 - 209,242,860 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,655,651 - 149,907,813 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4135,451,009 - 135,760,704 (-)NCBICelera
RGSC_v3.14149,903,289 - 150,220,388 (-)NCBI
RH 3.4 Map4948.3RGD
Cytogenetic Map4q42NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium acetate  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
dicrotophos  (ISO)
dopamine  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
fenoldopam  (EXP)
folic acid  (ISO)
furan  (ISO)
glycidol  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lycopene  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP)
poly(I:C)  (EXP)
propiconazole  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Expression of plasma membrane calcium-pumping ATPase mRNAs in developing rat brain and adult brain subregions: evidence for stage-specific expression. Brandt P and Neve RL, J Neurochem. 1992 Oct;59(4):1566-9.
3. Calcium pumps in health and disease. Brini M and Carafoli E, Physiol Rev. 2009 Oct;89(4):1341-78. doi: 10.1152/physrev.00032.2008.
4. Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke. Buga AM, etal., PLoS One. 2012;7(12):e50985. doi: 10.1371/journal.pone.0050985. Epub 2012 Dec 12.
5. Perisynaptic organization of plasma membrane calcium pumps in cerebellar cortex. Burette A and Weinberg RJ, J Comp Neurol. 2007 Feb 20;500(6):1127-35. doi: 10.1002/cne.21237.
6. A plasma membrane Ca2+ ATPase isoform at the postsynaptic density. Burette AC, etal., Neuroscience. 2010 Sep 1;169(3):987-93. doi: 10.1016/j.neuroscience.2010.05.062. Epub 2010 Jun 3.
7. Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum. Garside ML, etal., Neuroscience. 2009 Aug 18;162(2):383-95. Epub 2009 May 3.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
10. PMCA2 via PSD-95 controls calcium signaling by alpha7-containing nicotinic acetylcholine receptors on aspiny interneurons. Gomez-Varela D, etal., J Neurosci. 2012 May 16;32(20):6894-905. doi: 10.1523/JNEUROSCI.5972-11.2012.
11. Molecular determinants for differential membrane trafficking of PMCA1 and PMCA2 in mammalian hair cells. Grati M, etal., J Cell Sci. 2006 Jul 15;119(Pt 14):2995-3007. Epub 2006 Jun 27.
12. Rapid turnover of stereocilia membrane proteins: evidence from the trafficking and mobility of plasma membrane Ca(2+)-ATPase 2. Grati M, etal., J Neurosci. 2006 Jun 7;26(23):6386-95.
13. Partitioning of the plasma membrane Ca2+-ATPase into lipid rafts in primary neurons: effects of cholesterol depletion. Jiang L, etal., J Neurochem. 2007 Jul;102(2):378-88.
14. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
19. Ontogeny of plasma membrane Ca2+ ATPase isoforms in the neural retina of the postnatal rat. Renteria RC, etal., Vis Neurosci. 2005 May-Jun;22(3):263-74.
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump. Sgambato-Faure V, etal., Biochem Biophys Res Commun. 2006 May 5;343(2):630-7. Epub 2006 Mar 15.
23. Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases. Shull GE and Greeb J, J Biol Chem 1988 Jun 25;263(18):8646-57.
24. Disrupted placental vitamin D metabolism and calcium signaling in gestational diabetes and pre-eclampsia patients. Varshney S, etal., Endocrine. 2023 Apr;80(1):191-200. doi: 10.1007/s12020-022-03272-9. Epub 2022 Dec 8.
Additional References at PubMed
PMID:1315513   PMID:2765934   PMID:3038581   PMID:7518067   PMID:7683393   PMID:7929331   PMID:8428948   PMID:9325047   PMID:9668038   PMID:9697703   PMID:10441500   PMID:10687933  
PMID:11259493   PMID:11786550   PMID:11875276   PMID:11950541   PMID:11985881   PMID:12624087   PMID:15302868   PMID:15350283   PMID:15765049   PMID:15829536   PMID:16529873   PMID:16763025  
PMID:16845470   PMID:16880690   PMID:17170045   PMID:17234811   PMID:17409239   PMID:17823248   PMID:17970729   PMID:18570454   PMID:18643776   PMID:19025983   PMID:19120150   PMID:19410650  
PMID:19653992   PMID:20398509   PMID:20489728   PMID:21798237   PMID:22672315   PMID:22871113   PMID:24269647   PMID:25014339   PMID:25276815   PMID:25315779   PMID:28153703   PMID:29476059  
PMID:31032369   PMID:36707954  


Genomics

Comparative Map Data
Atp2b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,450,207 - 148,763,653 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)EnsemblGRCr8
mRatBN7.24146,894,602 - 147,208,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,896,332 - 147,140,665 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4152,279,141 - 152,592,499 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04148,060,008 - 148,373,376 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,688,239 - 147,002,829 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,704,779 - 145,948,997 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,703,046 - 146,016,325 (-)Ensemblrn6Rnor6.0
Rnor_5.04209,001,178 - 209,242,860 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44149,655,651 - 149,907,813 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4135,451,009 - 135,760,704 (-)NCBICelera
RGSC_v3.14149,903,289 - 150,220,388 (-)NCBI
RH 3.4 Map4948.3RGD
Cytogenetic Map4q42NCBI
ATP2B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38310,324,023 - 10,708,116 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl310,324,023 - 10,708,007 (-)Ensemblhg38GRCh38
GRCh37310,365,707 - 10,661,646 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36310,342,744 - 10,466,546 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34310,342,744 - 10,466,546NCBI
Celera310,301,512 - 10,482,740 (-)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef310,301,047 - 10,335,597 (-)NCBIHuRef
HuRef310,348,273 - 10,482,006 (-)NCBIHuRef
CHM1_1310,315,744 - 10,497,280 (-)NCBICHM1_1
T2T-CHM13v2.0310,317,333 - 10,702,408 (-)NCBIT2T-CHM13v2.0
Atp2b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,720,803 - 114,019,574 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,720,792 - 114,019,574 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386113,743,831 - 114,042,613 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,743,831 - 114,042,613 (-)Ensemblmm10GRCm38
MGSCv376113,695,662 - 113,992,020 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366113,711,445 - 114,007,621 (-)NCBIMGSCv36mm8
Celera6115,571,179 - 115,799,955 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.85NCBI
Atp2b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555611,727,935 - 1,851,907 (-)Ensembl
ChiLan1.0NW_0049555611,727,935 - 1,851,907 (-)NCBIChiLan1.0ChiLan1.0
ATP2B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2210,320,514 - 10,703,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1310,325,275 - 10,708,145 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0310,260,556 - 10,643,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1310,611,619 - 10,979,238 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl310,611,619 - 10,738,006 (-)EnsemblpanPan2panpan1.1
ATP2B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1207,665,468 - 8,037,407 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl207,749,807 - 8,034,474 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha207,700,708 - 8,073,696 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0207,695,736 - 8,069,081 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl207,695,764 - 8,067,042 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1207,411,304 - 7,790,973 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0207,763,652 - 8,136,675 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0207,736,523 - 8,110,287 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atp2b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,898,661 - 16,164,953 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366022,744,759 - 3,007,940 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366022,744,757 - 3,011,051 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP2B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1366,528,323 - 66,897,128 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11366,526,508 - 66,897,125 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ATP2B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12246,360,306 - 46,742,446 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2246,368,243 - 46,662,220 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041119,794,423 - 120,176,947 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp2b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247315,029,421 - 5,190,996 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247314,836,109 - 5,190,990 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Atp2b2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1632,479,315 - 32,789,906 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atp2b2
1439 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:3430
Count of miRNA genes:316
Interacting mature miRNAs:414
Transcripts:ENSRNOT00000043476, ENSRNOT00000044110, ENSRNOT00000049290, ENSRNOT00000050928, ENSRNOT00000064541, ENSRNOT00000067931
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
D3S3990  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,899,207 - 146,899,383 (+)MAPPERmRatBN7.2
Rnor_6.04145,707,654 - 145,707,829NCBIRnor6.0
Rnor_5.04209,004,053 - 209,004,228UniSTSRnor5.0
RGSC_v3.44149,658,526 - 149,658,701UniSTSRGSC3.4
Celera4135,453,884 - 135,454,059UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
RH142691  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24147,029,203 - 147,029,303 (+)MAPPERmRatBN7.2
Rnor_6.04145,837,969 - 145,838,068NCBIRnor6.0
Rnor_5.04209,132,438 - 209,132,537UniSTSRnor5.0
RGSC_v3.44149,793,065 - 149,793,164UniSTSRGSC3.4
Celera4135,581,970 - 135,582,069UniSTS
RH 3.4 Map4950.7UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
RH94465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,898,953 - 146,899,126 (+)MAPPERmRatBN7.2
Rnor_6.04145,707,400 - 145,707,572NCBIRnor6.0
Rnor_5.04209,003,799 - 209,003,971UniSTSRnor5.0
RGSC_v3.44149,658,272 - 149,658,444UniSTSRGSC3.4
Celera4135,453,630 - 135,453,802UniSTS
RH 3.4 Map4948.3UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
RH141415  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,926,607 - 146,926,799 (+)MAPPERmRatBN7.2
Rnor_6.04145,735,055 - 145,735,246NCBIRnor6.0
Rnor_5.04209,031,113 - 209,031,304UniSTSRnor5.0
RGSC_v3.44149,687,765 - 149,687,956UniSTSRGSC3.4
Celera4135,481,137 - 135,481,328UniSTS
RH 3.4 Map4947.1UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
Atp2b2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,896,756 - 146,897,034 (+)MAPPERmRatBN7.2
Rnor_6.04145,705,204 - 145,705,480NCBIRnor6.0
Rnor_5.04209,001,603 - 209,001,879UniSTSRnor5.0
RGSC_v3.44149,656,076 - 149,656,352UniSTSRGSC3.4
Celera4135,451,434 - 135,451,710UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
D6Mit141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24147,171,223 - 147,171,953 (+)MAPPERmRatBN7.2
Rnor_6.04145,979,550 - 145,980,279NCBIRnor6.0
Rnor_5.04209,273,413 - 209,274,142UniSTSRnor5.0
RGSC_v3.44149,938,366 - 149,939,095UniSTSRGSC3.4
Celera4135,723,972 - 135,724,701UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS
D3S2930E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,898,106 - 146,898,299 (+)MAPPERmRatBN7.2
Rnor_6.04145,706,553 - 145,706,745NCBIRnor6.0
Rnor_5.04209,002,952 - 209,003,144UniSTSRnor5.0
RGSC_v3.44149,657,425 - 149,657,617UniSTSRGSC3.4
Celera4135,452,783 - 135,452,975UniSTS
Cytogenetic Map4q41.3-q42.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 67 160 91 90 59 52 59 6 302 148 7 142 78 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC127397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000043476   ⟹   ENSRNOP00000045983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)Ensembl
mRatBN7.2 Ensembl4146,896,334 - 147,140,665 (-)Ensembl
Rnor_6.0 Ensembl4145,703,046 - 145,948,996 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000067931   ⟹   ENSRNOP00000060489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,896,332 - 147,140,665 (-)Ensembl
Rnor_6.0 Ensembl4145,704,779 - 146,016,325 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094304   ⟹   ENSRNOP00000097553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)Ensembl
mRatBN7.2 Ensembl4146,896,334 - 147,140,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095628   ⟹   ENSRNOP00000090928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,896,332 - 147,140,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098532   ⟹   ENSRNOP00000081850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)Ensembl
mRatBN7.2 Ensembl4146,896,334 - 147,140,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111682   ⟹   ENSRNOP00000090223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)Ensembl
mRatBN7.2 Ensembl4146,896,334 - 147,140,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115111   ⟹   ENSRNOP00000091175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,896,332 - 147,140,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120996   ⟹   ENSRNOP00000098554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,450,207 - 148,696,239 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120997   ⟹   ENSRNOP00000098555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,457,720 - 148,696,239 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120998   ⟹   ENSRNOP00000098556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4148,454,814 - 148,696,239 (-)Ensembl
RefSeq Acc Id: NM_012508   ⟹   NP_036640
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,450,207 - 148,763,653 (-)NCBI
mRatBN7.24146,894,602 - 147,208,060 (-)NCBI
Rnor_6.04145,704,779 - 145,948,997 (-)NCBI
Rnor_5.04209,001,178 - 209,242,860 (-)NCBI
RGSC_v3.44149,655,651 - 149,907,813 (-)RGD
Celera4135,451,009 - 135,760,704 (-)RGD
Sequence:
RefSeq Acc Id: XM_063285471   ⟹   XP_063141541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,763,595 (-)NCBI
RefSeq Acc Id: XM_063285472   ⟹   XP_063141542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,606,270 (-)NCBI
RefSeq Acc Id: XM_063285473   ⟹   XP_063141543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,763,595 (-)NCBI
RefSeq Acc Id: XM_063285474   ⟹   XP_063141544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,606,270 (-)NCBI
RefSeq Acc Id: XM_063285475   ⟹   XP_063141545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,606,270 (-)NCBI
RefSeq Acc Id: XM_063285476   ⟹   XP_063141546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,454,923 - 148,763,596 (-)NCBI
RefSeq Acc Id: XM_063285477   ⟹   XP_063141547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,606,270 (-)NCBI
RefSeq Acc Id: XM_063285478   ⟹   XP_063141548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,557,789 (-)NCBI
RefSeq Acc Id: XM_063285479   ⟹   XP_063141549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,763,596 (-)NCBI
RefSeq Acc Id: XM_063285480   ⟹   XP_063141550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,763,595 (-)NCBI
RefSeq Acc Id: XM_063285481   ⟹   XP_063141551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,451,934 - 148,606,270 (-)NCBI
RefSeq Acc Id: XR_010065611
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,454,923 - 148,763,596 (-)NCBI
RefSeq Acc Id: XR_010065612
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,454,923 - 148,763,596 (-)NCBI
RefSeq Acc Id: NP_036640   ⟸   NM_012508
- UniProtKB: A0A8L2QTH1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045983   ⟸   ENSRNOT00000043476
Ensembl Acc Id: ENSRNOP00000060489   ⟸   ENSRNOT00000067931
Ensembl Acc Id: ENSRNOP00000091175   ⟸   ENSRNOT00000115111
Ensembl Acc Id: ENSRNOP00000090223   ⟸   ENSRNOT00000111682
Ensembl Acc Id: ENSRNOP00000090928   ⟸   ENSRNOT00000095628
Ensembl Acc Id: ENSRNOP00000081850   ⟸   ENSRNOT00000098532
Ensembl Acc Id: ENSRNOP00000097553   ⟸   ENSRNOT00000094304
RefSeq Acc Id: XP_063141549   ⟸   XM_063285479
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ANJ1 (UniProtKB/TrEMBL),   A0A8I5ZSI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141550   ⟸   XM_063285480
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ADD4 (UniProtKB/TrEMBL),   A0A8I5ZSI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141543   ⟸   XM_063285473
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QTH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141541   ⟸   XM_063285471
- Peptide Label: isoform X1
- UniProtKB: Q63443 (UniProtKB/Swiss-Prot),   P11506 (UniProtKB/Swiss-Prot),   A0A8I6AF36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141547   ⟸   XM_063285477
- Peptide Label: isoform X5
- UniProtKB: A0A8L2QTH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141544   ⟸   XM_063285474
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QTH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141542   ⟸   XM_063285472
- Peptide Label: isoform X1
- UniProtKB: Q63443 (UniProtKB/Swiss-Prot),   P11506 (UniProtKB/Swiss-Prot),   A0A8I6AF36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141551   ⟸   XM_063285481
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AF36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141545   ⟸   XM_063285475
- Peptide Label: isoform X3
- UniProtKB: D4A8B3 (UniProtKB/TrEMBL),   A0A8I5ZSI6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141548   ⟸   XM_063285478
- Peptide Label: isoform X5
- UniProtKB: A0A8L2QTH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141546   ⟸   XM_063285476
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZSI6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000098555   ⟸   ENSRNOT00000120997
Ensembl Acc Id: ENSRNOP00000098554   ⟸   ENSRNOT00000120996
Ensembl Acc Id: ENSRNOP00000098556   ⟸   ENSRNOT00000120998
Protein Domains
Cation-transporting P-type ATPase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P11506-F1-model_v2 AlphaFold P11506 1-1243 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2176 AgrOrtholog
BioCyc Gene G2FUF-43362 BioCyc
Ensembl Genes ENSRNOG00000030269 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000043476 ENTREZGENE
  ENSRNOT00000095628.1 UniProtKB/Swiss-Prot
  ENSRNOT00000120996 ENTREZGENE
  ENSRNOT00000120997 ENTREZGENE
Gene3D-CATH 3.40.1110.10 UniProtKB/Swiss-Prot
  3.40.50.1000 UniProtKB/Swiss-Prot
  Calcium-transporting ATPase, cytoplasmic transduction domain A UniProtKB/Swiss-Prot
  Calcium-transporting ATPase, transmembrane domain UniProtKB/Swiss-Prot
InterPro ATP_Ca_trans_C UniProtKB/Swiss-Prot
  ATPase_P-typ_cation-transptr_C UniProtKB/Swiss-Prot
  ATPase_P-typ_cation-transptr_N UniProtKB/Swiss-Prot
  ATPase_P-typ_cyto_dom_N UniProtKB/Swiss-Prot
  ATPase_P-typ_P_site UniProtKB/Swiss-Prot
  ATPase_P-typ_TM_dom_sf UniProtKB/Swiss-Prot
  ATPase_P-typ_transduc_dom_A_sf UniProtKB/Swiss-Prot
  HAD-like_sf UniProtKB/Swiss-Prot
  HAD_sf UniProtKB/Swiss-Prot
  P-type_ATPase_IIB UniProtKB/Swiss-Prot
  P_typ_ATPase UniProtKB/Swiss-Prot
  P_typ_ATPase_HD_dom UniProtKB/Swiss-Prot
KEGG Report rno:24215 UniProtKB/Swiss-Prot
NCBI Gene 24215 ENTREZGENE
PANTHER CATION TRANSPORTING ATPASE UniProtKB/Swiss-Prot
  PTHR24093:SF377 UniProtKB/Swiss-Prot
Pfam ATP_Ca_trans_C UniProtKB/Swiss-Prot
  Cation_ATPase UniProtKB/Swiss-Prot
  Cation_ATPase_C UniProtKB/Swiss-Prot
  Cation_ATPase_N UniProtKB/Swiss-Prot
  E1-E2_ATPase UniProtKB/Swiss-Prot
  Hydrolase UniProtKB/Swiss-Prot
PhenoGen Atp2b2 PhenoGen
PRINTS CATATPASE UniProtKB/Swiss-Prot
  NAKATPASE UniProtKB/Swiss-Prot
PROSITE ATPASE_E1_E2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000030269 RatGTEx
SMART Cation_ATPase_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56784 UniProtKB/Swiss-Prot
  SSF81653 UniProtKB/Swiss-Prot
  SSF81660 UniProtKB/Swiss-Prot
  SSF81665 UniProtKB/Swiss-Prot
UniProt A0A8I5ZSI6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF36 ENTREZGENE
  A0A8I6ANJ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QTH1 ENTREZGENE
  A0ABK0L4U5_RAT UniProtKB/TrEMBL
  A0ABK0L5R3_RAT UniProtKB/TrEMBL
  A6IBU4_RAT UniProtKB/TrEMBL
  AT2B2_RAT UniProtKB/Swiss-Prot
  D4A8B3 ENTREZGENE, UniProtKB/TrEMBL
  P11506 ENTREZGENE
  Q63443 ENTREZGENE
UniProt Secondary Q63443 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Atp2b2  ATPase plasma membrane Ca2+ transporting 2  Atp2b2  ATPase, Ca++ transporting, plasma membrane 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Atp2b2  ATPase, Ca++ transporting, plasma membrane 2    ATPase isoform 2, Na+K+ transporting, beta polypeptide 2  Name updated 629478 APPROVED
2002-06-10 Atp2b2  ATPase isoform 2, Na+K+ transporting, beta polypeptide 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to plasma membrane 631720
gene_function Ca2+ ATPase 631720
gene_process plays an essential role in the regulation of intracellular Ca2+ levels 631720