Aldoc (aldolase, fructose-bisphosphate C) - Rat Genome Database

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Pathways
Gene: Aldoc (aldolase, fructose-bisphosphate C) Rattus norvegicus
Analyze
Symbol: Aldoc
Name: aldolase, fructose-bisphosphate C
RGD ID: 2091
Description: Enables fructose-bisphosphate aldolase activity and identical protein binding activity. Involved in animal organ regeneration and response to hypoxia. Located in axon. Is active in postsynaptic cytosol. Biomarker of borna disease and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C); PARTICIPATES IN fructose and mannose metabolic pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ALDCAA; aldolase C; aldolase C, fructose-biphosphate; aldolase C, fructose-bisphosphate; brain-type aldolase; F16dip7; fructose-bisphosphate aldolase C; RATALDCAA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Is Marker For: QTLs:   Stl1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,715,544 - 63,719,133 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1063,715,489 - 63,719,133 (+)EnsemblGRCr8
mRatBN7.21063,217,477 - 63,221,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,217,451 - 63,221,066 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1067,849,778 - 67,853,367 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,355,127 - 67,358,716 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,826,255 - 62,829,844 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,586,504 - 65,590,093 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,586,504 - 65,590,126 (+)Ensemblrn6Rnor6.0
Rnor_5.01066,049,065 - 66,052,654 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41064,308,826 - 64,312,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1062,195,147 - 62,198,736 (+)NCBICelera
RGSC_v3.11064,322,448 - 64,326,038 (-)NCBI
Cytogenetic Map10q25NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+/-)-Aegeline  (ISO)
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(RS)-coclaurine  (ISO)
(RS)-norcoclaurine  (ISO)
(S)-coclaurine  (ISO)
1,10-phenanthroline  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aconitine  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
ammonium chloride  (EXP)
Archazolid B  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
cisplatin  (ISO)
clozapine  (EXP,ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
diclofenac  (EXP)
diethyl phthalate  (EXP)
diethylstilbestrol  (ISO)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dizocilpine maleate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
Evodiamine  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
fluoxetine  (ISO)
flutamide  (EXP,ISO)
folpet  (ISO)
fructose  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
furfural  (ISO)
genistein  (EXP,ISO)
glucose  (ISO)
GSK-J4  (ISO)
haloperidol  (EXP)
herbicide  (ISO)
hydroxyurea  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
Macrosphelide A  (ISO)
maneb  (ISO)
manganese(II) chloride  (EXP)
methamphetamine  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylparaben  (ISO)
mifepristone  (ISO)
Moniliformin  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nitrates  (ISO)
NMN zwitterion  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
perfluorobutyric acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
Pf-06840003  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phenylpropanolamine  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-nitrosoglutathione  (ISO)
sarin  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
SKF 38393  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulindac sulfide  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
tapentadol  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
Yessotoxin  (ISO)
yohimbine  (ISO)
zearalenone  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IDA)
cytosol  (IBA)
postsynaptic cytosol  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Reappearance of aldolase C in rat liver during compensatory regeneration after partial hepatectomy. Berges J, etal., FEBS Lett. 1974 Nov 1;48(1):76-8.
2. Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease. Dale RC, etal., J Neuroimmunol. 2006 Mar;172(1-2):187-97. Epub 2005 Dec 13.
3. The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia. Dehnes Y, etal., J Neurosci. 1998 May 15;18(10):3606-19.
4. Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt-sensitive rat. Deng AY and Rapp JP, J Clin Invest 1995 May;95(5):2170-7
5. Studies on the fate of aldolase molecules in the aging rat lens. Dovrat A and Gershon D, Biochim Biophys Acta. 1983 May 25;757(2):164-7.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Reversal of the expression pattern of Aldolase C mRNA in Purkinje cells and Ube 1x mRNA in Golgi cells by a dopamine D1 receptor agonist injections in the methamphetamine sensitized-rat cerebellum. Hamamura M, etal., J Neural Transm. 2008 Jul;115(7):959-71. Epub 2008 Feb 26.
9. Location of adult and fetal aldolases A, B, and C by immunoperoxidase technique in LF fast-growing rat hepatomas. Hatzfeld A, etal., Cancer Res. 1978 Jan;38(1):16-22.
10. Purification of aldolase C from rat brain and hepatoma. Hatzfeld A, etal., Eur J Biochem. 1977 Jul 1;77(1):37-43.
11. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
12. Phospholipase D2 directly interacts with aldolase via Its PH domain. Kim JH, etal., Biochemistry. 2002 Mar 12;41(10):3414-21.
13. Aldolase C/zebrin II is released to the extracellular space after stroke and inhibits the network activity of cortical neurons. Linke S, etal., Neurochem Res. 2006 Nov;31(11):1297-303. Epub 2006 Oct 20.
14. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
15. The structure of the brain-specific rat aldolase C gene and its regional expression. Mukai T, etal., Biochem Biophys Res Commun 1991 Jan 31;174(2):1035-42.
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. GOA pipeline RGD automated data pipeline
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Comprehensive gene review and curation RGD comprehensive gene curation
21. The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones. Rottmann WH, etal., Biochimie 1987 Feb;69(2):137-45.
22. Molecular cloning and expression of rat aldolase C messenger RNA during development and hepatocarcinogenesis. Skala H, etal., Eur J Biochem. 1987 Mar 16;163(3):513-8.
23. Novel target sequences for Pax-6 in the brain-specific activating regions of the rat aldolase C gene. Skala-Rubinson H, etal., J Biol Chem 2002 Dec 6;277(49):47190-6.
24. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
25. Projection of reconstructed single Purkinje cell axons in relation to the cortical and nuclear aldolase C compartments of the rat cerebellum. Sugihara I, etal., J Comp Neurol. 2009 Jan 10;512(2):282-304.
26. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
27. Construction of rat aldolase C expression plasmid and the hybrid formation between rat aldolase C and human aldolase A or B co-expressed in Escherichia coli. Takasaki Y and Hori K, Protein Eng. 1990 Mar;3(4):273-7.
28. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
29. Spatiotemporal analysis of purkinje cell degeneration relative to parasagittal expression domains in a model of neonatal viral infection. Williams BL, etal., J Virol. 2007 Mar;81(6):2675-87. Epub 2006 Dec 20.
Additional References at PubMed
PMID:2831050   PMID:6696436   PMID:8168514   PMID:9244396   PMID:9443807   PMID:14651853   PMID:14697656   PMID:15489334   PMID:15537755   PMID:16854843   PMID:17183552   PMID:19056867  
PMID:19182904   PMID:20458337   PMID:21280042   PMID:21492153   PMID:22420779   PMID:22871113   PMID:23376485   PMID:23533145   PMID:31505169   PMID:32357304  


Genomics

Comparative Map Data
Aldoc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,715,544 - 63,719,133 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1063,715,489 - 63,719,133 (+)EnsemblGRCr8
mRatBN7.21063,217,477 - 63,221,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,217,451 - 63,221,066 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1067,849,778 - 67,853,367 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,355,127 - 67,358,716 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,826,255 - 62,829,844 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,586,504 - 65,590,093 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,586,504 - 65,590,126 (+)Ensemblrn6Rnor6.0
Rnor_5.01066,049,065 - 66,052,654 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41064,308,826 - 64,312,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1062,195,147 - 62,198,736 (+)NCBICelera
RGSC_v3.11064,322,448 - 64,326,038 (-)NCBI
Cytogenetic Map10q25NCBI
ALDOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,573,120 - 28,576,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,573,115 - 28,576,948 (-)Ensemblhg38GRCh38
GRCh371726,900,138 - 26,903,913 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,924,260 - 23,928,078 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341723,924,265 - 23,927,989NCBI
Celera1723,759,160 - 23,762,978 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,108,999 - 23,112,817 (-)NCBIHuRef
CHM1_11726,961,834 - 26,965,652 (-)NCBICHM1_1
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBIT2T-CHM13v2.0
Aldoc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,213,899 - 78,218,607 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,213,794 - 78,218,607 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381178,323,073 - 78,327,781 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,322,968 - 78,327,781 (+)Ensemblmm10GRCm38
MGSCv371178,137,700 - 78,140,262 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361178,140,393 - 78,142,955 (+)NCBIMGSCv36mm8
Celera1187,956,279 - 87,958,841 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Aldoc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,576,913 - 4,580,999 (+)Ensembl
ChiLan1.0NW_0049554814,576,913 - 4,580,999 (+)NCBIChiLan1.0ChiLan1.0
ALDOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21935,883,364 - 35,887,202 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,763,485 - 37,767,324 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,198,895 - 28,202,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,702,447 - 28,706,507 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,700,976 - 28,706,507 (+)EnsemblpanPan2panpan1.1
ALDOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,778,637 - 42,782,950 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,778,637 - 42,782,479 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha941,935,297 - 41,939,139 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0943,597,372 - 43,601,698 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,597,399 - 43,601,698 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,380,447 - 42,384,288 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,673,144 - 42,676,986 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,750,567 - 42,754,409 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Aldoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,921,047 - 41,924,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,798,989 - 4,802,994 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,798,991 - 4,802,700 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,822,780 - 44,827,597 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11244,823,376 - 44,827,273 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,807,780 - 46,811,676 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALDOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,342,750 - 22,346,811 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1622,341,318 - 22,346,620 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660757,779,923 - 7,784,075 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldoc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,158,248 - 1,162,916 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247861,158,270 - 1,162,801 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Aldoc
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1992,113,149 - 92,116,780 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Aldoc
55 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:48
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000015535, ENSRNOT00000046388
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104748901769161158Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105216243375582749Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105686844076129113Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
2306787Ean3Experimental allergic neuritis QTL 33.1nervous system integrity trait (VT:0010566)body weight loss (CMO:0001399)105429622767476781Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106184363383061236Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1331839Eae18bExperimental allergic encephalomyelitis QTL 18b5.80.03nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)106174653268282731Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
631526Bp76Blood pressure QTL 760.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106184363367241334Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Wox15  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81063,719,104 - 63,719,358 (+)Marker Load Pipeline
mRatBN7.21063,221,037 - 63,221,291 (+)MAPPERmRatBN7.2
Rnor_6.01065,590,065 - 65,590,318NCBIRnor6.0
Rnor_5.01066,048,840 - 66,049,093UniSTSRnor5.0
RGSC_v3.41064,308,600 - 64,308,854RGDRGSC3.4
RGSC_v3.41064,308,601 - 64,308,854UniSTSRGSC3.4
Celera1062,198,708 - 62,198,964UniSTS
RGSC_v3.11064,322,223 - 64,322,477RGD
RH 2.0 Map10606.0RGD
Cytogenetic Map10q25UniSTS
Cytogenetic Map10q31-q32.1UniSTS
D10Arb9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81063,719,161 - 63,719,290 (+)Marker Load Pipeline
mRatBN7.21063,221,094 - 63,221,223 (+)MAPPERmRatBN7.2
Rnor_6.01065,590,122 - 65,590,250NCBIRnor6.0
Rnor_5.01066,048,908 - 66,049,036UniSTSRnor5.0
RGSC_v3.41064,308,668 - 64,308,797RGDRGSC3.4
RGSC_v3.41064,308,669 - 64,308,797UniSTSRGSC3.4
Celera1062,198,765 - 62,198,896UniSTS
RGSC_v3.11064,322,291 - 64,322,420RGD
FHH x ACI Map1052.73RGD
FHH x ACI Map1052.73UniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map10q31-q32.1UniSTS
BE096286  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81063,717,342 - 63,717,581 (+)Marker Load Pipeline
mRatBN7.21063,219,275 - 63,219,514 (+)MAPPERmRatBN7.2
Rnor_6.01065,588,303 - 65,588,541NCBIRnor6.0
Rnor_5.01066,050,617 - 66,050,855UniSTSRnor5.0
RGSC_v3.41064,310,378 - 64,310,616UniSTSRGSC3.4
Celera1062,196,946 - 62,197,184UniSTS
Cytogenetic Map10q31-q32.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 90 59 6 344 190 11 143 71 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015535   ⟹   ENSRNOP00000015535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1063,715,489 - 63,719,126 (+)Ensembl
mRatBN7.2 Ensembl1063,217,451 - 63,221,064 (+)Ensembl
Rnor_6.0 Ensembl1065,586,504 - 65,590,093 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000046388   ⟹   ENSRNOP00000048591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1063,217,451 - 63,221,064 (+)Ensembl
Rnor_6.0 Ensembl1065,586,535 - 65,590,086 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086036   ⟹   ENSRNOP00000072735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1063,716,085 - 63,719,133 (+)Ensembl
mRatBN7.2 Ensembl1063,218,018 - 63,221,066 (+)Ensembl
Rnor_6.0 Ensembl1065,586,993 - 65,590,126 (+)Ensembl
RefSeq Acc Id: NM_012497   ⟹   NP_036629
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81063,715,544 - 63,719,133 (+)NCBI
mRatBN7.21063,217,477 - 63,221,066 (+)NCBI
Rnor_6.01065,586,504 - 65,590,093 (+)NCBI
Rnor_5.01066,049,065 - 66,052,654 (-)NCBI
RGSC_v3.41064,308,826 - 64,312,415 (-)RGD
Celera1062,195,147 - 62,198,736 (+)RGD
Sequence:
RefSeq Acc Id: NP_036629   ⟸   NM_012497
- UniProtKB: Q54AI4 (UniProtKB/Swiss-Prot),   Q63037 (UniProtKB/Swiss-Prot),   P09117 (UniProtKB/Swiss-Prot),   A6HH35 (UniProtKB/TrEMBL),   A0A0G2K3Q6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048591   ⟸   ENSRNOT00000046388
Ensembl Acc Id: ENSRNOP00000072735   ⟸   ENSRNOT00000086036
Ensembl Acc Id: ENSRNOP00000015535   ⟸   ENSRNOT00000015535

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09117-F1-model_v2 AlphaFold P09117 1-363 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697476
Promoter ID:EPDNEW_R8001
Type:initiation region
Name:Aldoc_1
Description:aldolase, fructose-bisphosphate C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01065,586,508 - 65,586,568EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2091 AgrOrtholog
BioCyc Gene G2FUF-24069 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY66-373 [sucrose degradation V (sucrose alpha-glucosidase)] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image ANAGLYCOLYSIS-PWY BioCyc
  PWY66-373 BioCyc
  PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000011452 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015535 ENTREZGENE
  ENSRNOT00000015535.9 UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599032 IMAGE-MGC_LOAD
InterPro Aldolase_I_AS UniProtKB/Swiss-Prot
  Aldolase_TIM UniProtKB/Swiss-Prot
  FBA_I UniProtKB/Swiss-Prot
KEGG Report rno:24191 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124642 IMAGE-MGC_LOAD
NCBI Gene 24191 ENTREZGENE
PANTHER PTHR11627 UniProtKB/Swiss-Prot
Pfam Glycolytic UniProtKB/Swiss-Prot
PhenoGen Aldoc PhenoGen
PROSITE ALDOLASE_CLASS_I UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011452 RatGTEx
Superfamily-SCOP Aldolase UniProtKB/Swiss-Prot
TIGR TC217615
UniProt A0A0G2K3Q6 ENTREZGENE, UniProtKB/TrEMBL
  A6HH31_RAT UniProtKB/TrEMBL
  A6HH33_RAT UniProtKB/TrEMBL
  A6HH34_RAT UniProtKB/TrEMBL
  A6HH35 ENTREZGENE, UniProtKB/TrEMBL
  A6HH37_RAT UniProtKB/TrEMBL
  A6HH40_RAT UniProtKB/TrEMBL
  A6HH41_RAT UniProtKB/TrEMBL
  A6HH42_RAT UniProtKB/TrEMBL
  ALDOC_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q54AI4 ENTREZGENE
  Q63037 ENTREZGENE
  Q6PCU3_RAT UniProtKB/TrEMBL
UniProt Secondary Q54AI4 UniProtKB/Swiss-Prot
  Q63037 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Aldoc  aldolase, fructose-bisphosphate C  Aldoc  aldolase C, fructose-bisphosphate  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Aldoc  aldolase C, fructose-bisphosphate  Aldoc  aldolase C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Aldoc  aldolase C    aldolase C, fructose-biphosphate  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed specifically in brain 632189
gene_expression expressed in cerebellar cortex Purkinje cells 632190
gene_process may be involved in neurogenesis 632189
gene_product member of the aldolase enzyme family 632189
gene_regulation expression may be regulated by Pax6 632189
gene_transcript has two transcription initiation sites 632190