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Gene: Ldlrad1 (low density lipoprotein receptor class A domain containing 1) Rattus norvegicus

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Symbol:

Ldlrad1

Name:

low density lipoprotein receptor class A domain containing 1

RGD ID:

1597398

Description:

Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Orthologous to human LDLRAD1 (low density lipoprotein receptor class A domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC689088; low-density lipoprotein receptor class A domain-containing protein 1; similar to low density lipoprotein receptor A domain containing 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	127,212,581 - 127,229,753 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	127,220,764 - 127,229,725 (+)	Ensembl				GRCr8
mRatBN7.2	5	121,984,245 - 122,000,941 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	121,991,690 - 122,000,944 (+)	Ensembl				mRatBN7.2
Rnor_6.0	5	126,812,168 - 126,821,437 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	126,812,187 - 126,821,407 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	130,656,707 - 130,670,458 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	128,298,413 - 128,307,513 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	120,737,404 - 120,746,763 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (EXP)

actinomycin D (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (EXP)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

Cuprizon (EXP)

diarsenic trioxide (ISO)

epoxiconazole (ISO)

flutamide (EXP)

Nutlin-3 (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trametinib (ISO)

trichloroethene (EXP)

triptonide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

vesicle-mediated transport (IEA)

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Ldlrad1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	127,212,581 - 127,229,753 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	127,220,764 - 127,229,725 (+)	Ensembl				GRCr8
mRatBN7.2	5	121,984,245 - 122,000,941 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	121,991,690 - 122,000,944 (+)	Ensembl				mRatBN7.2
Rnor_6.0	5	126,812,168 - 126,821,437 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	126,812,187 - 126,821,407 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	130,656,707 - 130,670,458 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	128,298,413 - 128,307,513 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	120,737,404 - 120,746,763 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

LDLRAD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	54,007,298 - 54,018,186 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	54,007,298 - 54,018,194 (-)	Ensembl			hg38	GRCh38
GRCh37	1	54,472,971 - 54,483,859 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	54,247,094 - 54,256,391 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	52,762,183 - 52,771,480 (-)	NCBI		Celera
Cytogenetic Map	1	p32.3	NCBI
HuRef	1	52,588,682 - 52,599,569 (-)	NCBI		HuRef
CHM1_1	1	54,589,314 - 54,600,202 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	53,890,196 - 53,901,083 (-)	NCBI		T2T-CHM13v2.0

Ldlrad1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	107,066,264 - 107,081,341 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	107,066,377 - 107,075,257 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	107,209,078 - 107,221,092 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	107,209,180 - 107,218,060 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	106,881,785 - 106,890,519 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	106,707,112 - 106,715,846 (+)	NCBI		MGSCv36	mm8
Celera	4	105,571,146 - 105,579,973 (+)	NCBI		Celera
Cytogenetic Map	4	C7	NCBI
cM Map	4	50.16	NCBI

Ldlrad1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	5,233,216 - 5,240,522 (+)	Ensembl
ChiLan1.0	NW_004955464	5,233,134 - 5,243,730 (+)	NCBI	ChiLan1.0	ChiLan1.0

LDLRAD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	172,818,318 - 172,831,689 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	171,959,113 - 171,972,382 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	53,281,097 - 53,292,010 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	54,875,019 - 54,885,898 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	54,875,019 - 54,885,898 (-)	Ensembl			panPan2	panpan1.1

LDLRAD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	54,995,125 - 55,004,578 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	55,000,029 - 55,003,903 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	55,063,468 - 55,071,248 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	55,184,685 - 55,192,457 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	5	55,179,144 - 55,186,880 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	55,068,720 - 55,076,494 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	55,458,409 - 55,466,182 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ldlrad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	68,264,262 - 68,275,790 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936522	7,141,029 - 7,149,097 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936522	7,140,568 - 7,149,135 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LDLRAD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	158,292,616 - 158,303,012 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	158,292,303 - 158,304,202 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	145,892,589 - 145,902,795 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LDLRAD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	78,917,202 - 78,926,800 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666033	38,355,845 - 38,365,234 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ldlrad1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624934	493,380 - 501,229 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624934	492,954 - 502,554 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ldlrad1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	47,592,679 - 47,601,549 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ldlrad1
135 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	95
Count of miRNA genes:	83
Interacting mature miRNAs:	86
Transcripts:	ENSRNOT00000057372
Prediction methods:	Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
2303586	Gluco52	Glucose level QTL 52	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	100826632	145826632	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	116702075	161702075	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	84630798	129630798	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
1582230	Bw78	Body weight QTL 78	3.2	0.0016	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	124314582	133270832	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	84630798	129630798	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112142946	157142946	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112142946	157142946	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	110770739	155770739	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112142946	157142946	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	92583776	137583776	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	98972960	143972960	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	125969677	172190305	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
2303618	Vencon1	Ventilatory control QTL 1	3.8		respiration trait (VT:0001943)	oxygen consumption (CMO:0002169)	5	100826632	145826632	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111236572	156236572	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84630798	129630798	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	94034903	139034903	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114131300	159131300	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	125969677	156302135	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	95062526	133270832	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112142946	157142946	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	116702075	161702075	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112142946	157142946	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	116702075	161702075	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	116702075	161702075	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	89369373	134369373	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114131300	159131300	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	97492524	133270832	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	92881678	137881678	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	95062526	133270832	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	161	91	90	59	92	59	6	355	191	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006225444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593782	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111145	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057372 ⟹ ENSRNOP00000054184

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	127,220,764 - 127,229,725 (+)	Ensembl
mRatBN7.2 Ensembl	5	121,991,690 - 122,000,944 (+)	Ensembl
Rnor_6.0 Ensembl	5	126,812,187 - 126,821,407 (+)	Ensembl

RefSeq Acc Id:

XM_006238557 ⟹ XP_006238619

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,490 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,991,679 - 122,000,941 (+)	NCBI
Rnor_6.0	5	126,812,168 - 126,821,437 (+)	NCBI
Rnor_5.0	5	130,656,707 - 130,670,458 (+)	NCBI

Sequence:

show sequence

GGGGGTGGGGGTACCTGAGTCTGTTGGTGCAGAGGAGGAAAAGCGTGCTAAAGCCCTGGTTCAT
CTCTCCCACGTATAGCGTGACTCGAAGCACAAACAGCAGCTTGTCATCTGTGGAATGGGAAGTG
TCCCTGTCCAACTGCAACCTAGGGAGACACTTGGTAGGAGCAGGCTGCCCCTGGTGACAAGGCA
GAGGACTCTACACTGAGCTCTCCTTGTTCCACAACAGTTCCTGGAGATGAGTGTTGGAGCCATG
AACAAAATCTGCCCACAGGCAGATGCCGAGAGCAACATGACCACTGGAAGGAAAACCCGCCCTG
GAGGTGAAGGCTGTGGCCCCCTCTGCTACTCACGCCGCGGGGCCTGCCTTTCTGTCTTCCTGCT
GCTTCTGCTGGCCATGCTTGCCGCCTTGCTCTTGATCGTCACCATCCTGGGACATCCACAGCGC
ACACCAGAGCCTCACTCTTGTGTGACACTGGCCAACAGGACGGGGTTCTTGTGCCATGACCGAA
GGTACTGCATCCCGGCCCATGCCGTGTGTGATGGCATCCGCACCTGTCCTCATGGTGAGGACGA
GGCTGAGAACTTGTGTCGAGATTTGCCCAAGAGCCTCCCCAGCTTCCTCCTGACCACCTGTGGA
AACCCAGACTCCTGGATCTACTCAGACCAGAAATGTGATGGCACCAACAACTGTGGGGACTGCT
CAGATGAGCTGAGCCCAGTGACTGCGTGCCCACCCTGTGGCCCTGGGTGGTGGTATTGCACTCC
AACTGTGTTCAGGTACTGCAGCTGTGTCCCGAGGGTCCTGTGCCGGGACGGAGTGCAGCACTGC
TCTGACTGGTCCGATGAGTACTCCTGTCCTGGACCCTGAGTGAGCCTCATGGTCTGGGTCAGCA
TGGAAGCTGGCACCCGGAACCTTAGACCGGAGCACCGAAGCCTACACCACAAGGGCAGGAAGAA
ACCTTTGTCATCCACCAGTGGCACCTAGCCCCCATGGTCTCTGAACAGGAATTCAAGTGTCTCA
GCCTCCACCTGAGCACTTCCAATGACACGGAGCTCACCACCATGTTAGGCAGATTCTAACAAAG
ATGAGGCGGCCTCCTCCATCACTTTAGGCCTGTCAATGAGACCACAGGAGAAATGCTCCTTGAC
TCCAGGGCAGACTTGAAGTCCCAATCTTGTCATTCCTGGAAGAGACAAATGTGTGGCTTAAATA
CCAAGTGAGTTTAGCCCTGTGGGTAGAAAACAAAGCACACACATTTACCACCATTCGGTGCCTA
AGGCAGGAACTCAAGGCCCCTGGAGCTTCTTGCCCAACTCACCAGCAGCCCCGACTGATCACAT
GAGGTTGCACATGGCACTTGGGACCTGGAATCTTTCTAGTTTCCCAGTATCCTAGAGGCTTGTG
GCTGTGGAGTAGAAGACCCAGAGACAGTGCAGCTTAGAAGAACCCCTCTATGCCTTTAGTCTTA
GCCTCTGCCTTGCTTCACCCCACAATTGCCTGCAGGTTTATATTTTGGTCCTGCAGCCAGGACC
TATATACCTTGCATATCTTCTAGCTTTACAACACCCACCCAGGCAAGGATGGGTGTGCTCATTA
GACAGATGAGGAAACAGAGGCCTAGGGGATGACTTGCCCAGGGTATACTCTGGAACTGGGACTC
AAAGTCAGTCTGCAGAACTCTGACCTCAGGGTCTTCCCCACTATTAATGGGGAAGAGAGATGGG
CTAGAGAGATGGCTCAGCAGTTAAGAGCCATGGCTGCTCTTCCAGAGGTCCTGAGTTCAATACC
CAGCAACCACATGGTGGCTCACAACCATCTGTAATAGGATCTGATGCCCTCTTTGGGTATGTCT
GAAGACAGCTACAGTGTGCTTATATAAATAAAAAAATAAATATTTAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039111136 ⟹ XP_038967064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,212,892 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,984,253 - 122,000,941 (+)	NCBI

RefSeq Acc Id:

XM_039111141 ⟹ XP_038967069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,616 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,991,794 - 122,000,941 (+)	NCBI

RefSeq Acc Id:

XM_039111143 ⟹ XP_038967071

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,490 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,991,679 - 122,000,941 (+)	NCBI

RefSeq Acc Id:

XM_039111144 ⟹ XP_038967072

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,491 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,991,679 - 122,000,941 (+)	NCBI

RefSeq Acc Id:

XM_039111145 ⟹ XP_038967073

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,491 - 127,229,753 (+)	NCBI
mRatBN7.2	5	121,991,679 - 122,000,941 (+)	NCBI

RefSeq Acc Id:

XM_063261321 ⟹ XP_063117391

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,212,581 - 127,229,753 (+)	NCBI

RefSeq Acc Id:

XM_063261322 ⟹ XP_063117392

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,487 - 127,229,753 (+)	NCBI

RefSeq Acc Id:

XM_063261323 ⟹ XP_063117393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	127,220,487 - 127,229,753 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_006238619	(Get FASTA)	NCBI Sequence Viewer
	XP_038967064	(Get FASTA)	NCBI Sequence Viewer
	XP_038967069	(Get FASTA)	NCBI Sequence Viewer
	XP_038967071	(Get FASTA)	NCBI Sequence Viewer
	XP_038967072	(Get FASTA)	NCBI Sequence Viewer
	XP_038967073	(Get FASTA)	NCBI Sequence Viewer
	XP_063117391	(Get FASTA)	NCBI Sequence Viewer
	XP_063117392	(Get FASTA)	NCBI Sequence Viewer
	XP_063117393	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054184
	ENSRNOP00000054184.4

RefSeq Acc Id:	XP_006238619 ⟸ XM_006238557
- Peptide Label:	isoform X3
- UniProtKB:	D4A460 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSVGAMNKICPQADAESNMTTGRKTRPGGEGCGPLCYSRRGACLSVFLLLLLAMLAALLLIVTI LGHPQRTPEPHSCVTLANRTGFLCHDRRYCIPAHAVCDGIRTCPHGEDEAENLCRDLPKSLPSF LLTTCGNPDSWIYSDQKCDGTNNCGDCSDELSPVTACPPCGPGWWYCTPTVFRYCSCVPRVLCR DGVQHCSDWSDEYSCPGP hide sequence

Ensembl Acc Id:

ENSRNOP00000054184 ⟸ ENSRNOT00000057372

RefSeq Acc Id:	XP_038967064 ⟸ XM_039111136
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038967073 ⟸ XM_039111145
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_038967071 ⟸ XM_039111143
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038967072 ⟸ XM_039111144
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038967069 ⟸ XM_039111141
- Peptide Label:	isoform X3
- UniProtKB:	D4A460 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117391 ⟸ XM_063261321
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063117392 ⟸ XM_063261322
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063117393 ⟸ XM_063261323
- Peptide Label:	isoform X8

Protein Domains

LDLRAD1-like C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A460-F1-model_v2	AlphaFold	D4A460	1-210	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1597398	AgrOrtholog
BioCyc Gene	G2FUF-40422	BioCyc
Ensembl Genes	ENSRNOG00000037795	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000057372	ENTREZGENE
	ENSRNOT00000057372.6	UniProtKB/TrEMBL
Gene3D-CATH	4.10.400.10	UniProtKB/TrEMBL
InterPro	LDL_receptor-like_sf	UniProtKB/TrEMBL
	LDLR	UniProtKB/TrEMBL
	LDLR_classA_rpt	UniProtKB/TrEMBL
	LDLRAD1_C	UniProtKB/TrEMBL
KEGG Report	rno:689088	UniProtKB/TrEMBL
NCBI Gene	689088	ENTREZGENE
PANTHER	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED	UniProtKB/TrEMBL
Pfam	Ldl_recept_a	UniProtKB/TrEMBL
	LDLRAD1_C	UniProtKB/TrEMBL
PhenoGen	Ldlrad1	PhenoGen
PRINTS	LDLRECEPTOR	UniProtKB/TrEMBL
PROSITE	LDLRA_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000037795	RatGTEx
SMART	LDLa	UniProtKB/TrEMBL
Superfamily-SCOP	LDL_rcpt_classA_cys-rich	UniProtKB/TrEMBL
UniProt	D4A460	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Ldlrad1	low density lipoprotein receptor class A domain containing 1	LOC689088	similar to low density lipoprotein receptor A domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC689088	similar to low density lipoprotein receptor A domain containing 1	LOC683455	similar to low density lipoprotein receptor A domain containing 1	Data merged from RGD:1586835	1643240	APPROVED
2006-11-20	LOC689088	similar to low density lipoprotein receptor A domain containing 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC683455	similar to low density lipoprotein receptor A domain containing 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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