Gene: Tead2 (TEA domain transcription factor 2) Rattus norvegicus
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Symbol:
Tead2
Name:
TEA domain transcription factor 2
RGD ID:
1593252
Description:
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; disordered domain specific binding activity; and transcription coactivator binding activity. Predicted to be involved in several processes, including embryonic organ development; hippo signaling; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including cellular response to retinoic acid; paraxial mesoderm development; and tube morphogenesis. Predicted to be located in nucleoplasm. Predicted to be part of TEAD-YAP complex. Orthologous to human TEAD2 (TEA domain transcription factor 2); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
embryonic TEA domain containing factor; TEA domain family member 2; TEA domain family member 2 (mapped); Tead2_mapped; transcriptional enhancer factor TEF-4
RGD Orthologs
Alliance Orthologs
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Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 104,838,795 - 104,855,635 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 1 104,838,623 - 104,855,630 (+) Ensembl GRCr8 mRatBN7.2 1 95,702,366 - 95,719,186 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 95,703,005 - 95,719,186 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 1 101,088,694 - 101,104,579 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 109,561,364 - 109,577,250 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 102,851,763 - 102,867,647 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 101,213,782 - 101,230,483 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 101,213,788 - 101,230,477 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 1 102,278,640 - 102,295,457 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 1 95,694,077 - 95,709,961 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 1 89,961,576 - 89,977,460 (+) NCBI Celera Cytogenetic Map 1 q22 NCBI
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Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Tead2 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TEAD2 mRNA] CTD PMID:31150632 Tead2 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Tead2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tead2 Rat 1,2-dichloroethane increases expression ISO Tead2 (Mus musculus) 6480464 ethylene dichloride results in increased expression of TEAD2 mRNA CTD PMID:28960355 Tead2 Rat 1,2-dimethylhydrazine increases expression ISO Tead2 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of TEAD2 mRNA CTD PMID:22206623 Tead2 Rat 17beta-estradiol multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of TEAD2 mRNA CTD PMID:30165855 Tead2 Rat 17beta-estradiol decreases expression ISO TEAD2 (Homo sapiens) 6480464 Estradiol results in decreased expression of TEAD2 mRNA CTD PMID:31614463 Tead2 Rat 17beta-estradiol decreases expression ISO Tead2 (Mus musculus) 6480464 Estradiol results in decreased expression of TEAD2 mRNA CTD PMID:39298647 Tead2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Tead2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tead2 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Tead2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tead2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Tead2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of TEAD2 mRNA CTD PMID:21570461|PMID:24058054 Tead2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO TEAD2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of TEAD2 mRNA CTD PMID:22574217 Tead2 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Tead2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tead2 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2,4-dinitrotoluene affects the expression of TEAD2 mRNA CTD PMID:21346803 Tead2 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Tead2 (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of TEAD2 mRNA CTD PMID:25172293 Tead2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TEAD2 mRNA CTD PMID:24780913 Tead2 Rat acrylamide decreases expression ISO TEAD2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of TEAD2 mRNA CTD PMID:32763439 Tead2 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TEAD2 mRNA CTD PMID:35163327 Tead2 Rat aristolochic acid A decreases expression ISO TEAD2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of TEAD2 mRNA CTD PMID:33212167 Tead2 Rat arsane multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TEAD2 more ... CTD PMID:39836092 Tead2 Rat arsenic atom multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TEAD2 more ... CTD PMID:39836092 Tead2 Rat azoxystrobin multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... CTD PMID:33854195 Tead2 Rat benzo[a]pyrene increases methylation ISO TEAD2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of TEAD2 3' UTR CTD PMID:27901495 Tead2 Rat benzo[a]pyrene increases expression ISO TEAD2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TEAD2 mRNA CTD PMID:32234424 Tead2 Rat bis(2-ethylhexyl) phthalate increases expression ISO Tead2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of TEAD2 mRNA CTD PMID:33754040 Tead2 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Tead2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of TEAD2 mRNA CTD PMID:34319233 Tead2 Rat bisphenol A decreases expression ISO Tead2 (Mus musculus) 6480464 bisphenol A results in decreased expression of TEAD2 mRNA CTD PMID:26063408 Tead2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TEAD2 mRNA CTD PMID:41034487 Tead2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TEAD2 mRNA CTD PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 Tead2 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of TEAD2 mRNA CTD PMID:33453195 Tead2 Rat chlorpyrifos decreases expression ISO Tead2 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of TEAD2 mRNA CTD PMID:32715474 Tead2 Rat chlorpyrifos multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... CTD PMID:33854195 Tead2 Rat copper atom multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TEAD2 mRNA CTD PMID:20971185 Tead2 Rat copper atom increases expression EXP 6480464 Copper results in increased expression of TEAD2 mRNA CTD PMID:30556269 Tead2 Rat copper(0) multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TEAD2 mRNA CTD PMID:20971185 Tead2 Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of TEAD2 mRNA CTD PMID:30556269 Tead2 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of TEAD2 mRNA CTD PMID:26577399 Tead2 Rat diazinon increases methylation ISO TEAD2 (Homo sapiens) 6480464 Diazinon results in increased methylation of TEAD2 gene CTD PMID:22964155 Tead2 Rat dimethylarsinic acid increases methylation EXP 6480464 Cacodylic Acid results in increased methylation of TEAD2 gene CTD PMID:37958445 Tead2 Rat dorsomorphin multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tead2 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TEAD2 mRNA CTD PMID:29391264 Tead2 Rat entinostat decreases expression ISO TEAD2 (Homo sapiens) 6480464 entinostat results in decreased expression of TEAD2 mRNA CTD PMID:27188386 Tead2 Rat ethanol multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Tead2 Rat fenamidone increases expression ISO Tead2 (Mus musculus) 6480464 fenamidone results in increased expression of TEAD2 mRNA CTD PMID:27029645 Tead2 Rat gallic acid decreases expression ISO TEAD2 (Homo sapiens) 6480464 Gallic Acid results in decreased expression of TEAD2 mRNA CTD PMID:34408198 Tead2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of TEAD2 mRNA CTD PMID:33387578 Tead2 Rat glyphosate multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... CTD PMID:33854195 Tead2 Rat imidacloprid multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... CTD PMID:33854195 Tead2 Rat lead(0) affects expression ISO TEAD2 (Homo sapiens) 6480464 Lead affects the expression of TEAD2 mRNA CTD PMID:28903495 Tead2 Rat lipopolysaccharide multiple interactions ISO Tead2 (Mus musculus) 6480464 TEAD2 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; TEAD2 protein more ... CTD PMID:21131441 Tead2 Rat lipopolysaccharide increases response to substance ISO Tead2 (Mus musculus) 6480464 TEAD2 protein results in increased susceptibility to Lipopolysaccharides CTD PMID:21131441 Tead2 Rat methylmercury chloride increases expression ISO TEAD2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of TEAD2 mRNA CTD PMID:28001369 Tead2 Rat O-methyleugenol increases expression ISO TEAD2 (Homo sapiens) 6480464 methyleugenol results in increased expression of TEAD2 mRNA CTD PMID:32234424 Tead2 Rat orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of TEAD2 mRNA CTD PMID:23665939 Tead2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of TEAD2 mRNA CTD PMID:33387578 Tead2 Rat PCB138 multiple interactions ISO Tead2 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Tead2 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of TEAD2 mRNA CTD PMID:35163327 Tead2 Rat pirinixic acid increases expression ISO Tead2 (Mus musculus) 6480464 pirinixic acid results in increased expression of TEAD2 mRNA CTD PMID:23811191 Tead2 Rat SB 431542 multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tead2 Rat silver atom increases expression ISO Tead2 (Mus musculus) 6480464 Silver results in increased expression of TEAD2 mRNA CTD PMID:27131904 Tead2 Rat silver(0) increases expression ISO Tead2 (Mus musculus) 6480464 Silver results in increased expression of TEAD2 mRNA CTD PMID:27131904 Tead2 Rat sodium arsenite decreases expression ISO TEAD2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of TEAD2 mRNA CTD PMID:38568856 Tead2 Rat sodium arsenite decreases methylation ISO Tead2 (Mus musculus) 6480464 sodium arsenite results in decreased methylation of TEAD2 gene CTD PMID:39894169 Tead2 Rat sodium arsenite multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TEAD2 more ... CTD PMID:39836092 Tead2 Rat sulforaphane decreases expression ISO TEAD2 (Homo sapiens) 6480464 sulforaphane results in decreased expression of TEAD2 mRNA CTD PMID:31838189 Tead2 Rat temozolomide increases expression ISO TEAD2 (Homo sapiens) 6480464 Temozolomide results in increased expression of TEAD2 mRNA CTD PMID:31758290 Tead2 Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TEAD2 mRNA] CTD PMID:31150632 Tead2 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of TEAD2 mRNA CTD PMID:31150632 Tead2 Rat thapsigargin decreases expression ISO TEAD2 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of TEAD2 mRNA CTD PMID:22378314 Tead2 Rat thiabendazole multiple interactions EXP 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with more ... CTD PMID:33854195 Tead2 Rat thiram decreases expression ISO TEAD2 (Homo sapiens) 6480464 Thiram results in decreased expression of TEAD2 mRNA CTD PMID:38568856 Tead2 Rat titanium dioxide decreases methylation ISO Tead2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of TEAD2 gene CTD PMID:35295148 Tead2 Rat titanium dioxide increases methylation ISO Tead2 (Mus musculus) 6480464 titanium dioxide results in increased methylation of TEAD2 gene CTD PMID:35295148 Tead2 Rat tris(2-butoxyethyl) phosphate affects expression ISO TEAD2 (Homo sapiens) 6480464 tris(2-butoxyethyl) phosphate affects the expression of TEAD2 mRNA CTD PMID:29024780 Tead2 Rat tunicamycin decreases expression ISO TEAD2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of TEAD2 mRNA CTD PMID:22378314 Tead2 Rat urethane decreases expression ISO TEAD2 (Homo sapiens) 6480464 Urethane results in decreased expression of TEAD2 mRNA CTD PMID:28818685 Tead2 Rat valproic acid decreases expression ISO Tead2 (Mus musculus) 6480464 Valproic Acid results in decreased expression of TEAD2 mRNA CTD PMID:21427059 Tead2 Rat valproic acid increases expression ISO Tead2 (Mus musculus) 6480464 Valproic Acid results in increased expression of TEAD2 mRNA CTD PMID:21427059 Tead2 Rat valproic acid affects expression ISO TEAD2 (Homo sapiens) 6480464 Valproic Acid affects the expression of TEAD2 mRNA CTD PMID:25979313 Tead2 Rat valproic acid multiple interactions ISO TEAD2 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Tead2 Rat valproic acid decreases expression ISO TEAD2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of TEAD2 mRNA CTD PMID:23179753|PMID:24935251|PMID:26272509|PMID:27188386|PMID:28001369|PMID:29154799 Tead2 Rat zoledronic acid decreases expression ISO TEAD2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of TEAD2 mRNA CTD PMID:24714768