Gene: Tead2 (TEA domain family member 2)
Mus musculus
Symbol:
Tead2
Name:
TEA domain family member 2
Description:
ENCODES a protein that exhibits DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity (ortholog); INVOLVED IN embryonic heart tube morphogenesis; lateral mesoderm development; negative regulation of cell death; ASSOCIATED WITH abnormal allantois morphology; abnormal developmental patterning; abnormal embryo turning; FOUND IN transcription factor complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; valproic acid; 2,4-dinitrotoluene (ortholog)
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
embryonic TEA domain-containing factor; Etdf; ETEF-1; ETF; OTTMUSP00000030804; OTTMUSP00000030805; OTTMUSP00000030806; OTTMUSP00000030807; TEAD-2; TEF-4; TEF4; transcriptional enhancer factor TEF-4
Orthologs:
Homo sapiens : TEAD2
(TEA domain family member 2)
HGNC
Rattus norvegicus : Tead2
(TEA domain family member 2)
Latest Assembly:
Mouse Genome Assembly Build 37
Position:
Map Chr Position Strand Source Mouse Genome Assembly GRCm38 7 45,215,753 - 45,233,619 + NCBI Mouse cM Map 7 29.19 NCBI Mouse Celera Assembly 7 40,671,641 - 40,689,485 + NCBI Mouse Genome Assembly Build 37 7 52,471,123 - 52,488,989 + NCBI Mouse Genome Assembly Build 36.1 7 52,471,123 - 52,488,989 + NCBI Mouse Cytogenetic Map 7 B5 NCBI
Model
Gene Ontology Annotations
Biological Process
embryonic heart tube morphogenesis IGI MGI:MGI:101876|MGI:MGI:103262 2290270 MGI:MGI:3773640|PMID:18332127 MGI MGI:MGI:3773640 PMID:18332127 hippo signaling cascade ISO UniProtKB:Q15562 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 lateral mesoderm development IGI MGI:MGI:101876|MGI:MGI:103262 2290270 MGI:MGI:3773640|PMID:18332127 MGI MGI:MGI:3773640 PMID:18332127 negative regulation of cell death IGI UniProtKB:Q06831|UniProtKB:Q7M6Y2 2290270 MGI:MGI:5285157|PMID:20596238 UniProtKB MGI:MGI:5285157 PMID:20596238 neural tube closure IMP MGI:MGI:3763367 2290270 MGI:MGI:3763398|PMID:17868131 MGI MGI:MGI:3763398 PMID:17868131 notochord development IGI MGI:MGI:101876|MGI:MGI:103262 2290270 MGI:MGI:3773640|PMID:18332127 MGI MGI:MGI:3773640 PMID:18332127 paraxial mesoderm development IGI MGI:MGI:101876|MGI:MGI:103262 2290270 MGI:MGI:3773640|PMID:18332127 MGI MGI:MGI:3773640 PMID:18332127 positive regulation of transcription from RNA polymerase II promoter IGI MGI:MGI:103262 2290270 MGI:MGI:3608264|PMID:16207754 MGI MGI:MGI:3608264 PMID:16207754 positive regulation of transcription from RNA polymerase II promoter IDA 2290270 MGI:MGI:1197427|PMID:9502435 MGI MGI:MGI:1197427 PMID:9502435 positive regulation of transcription from RNA polymerase II promoter IDA 2290270 MGI:MGI:3027470|PMID:14736747 MGI MGI:MGI:3027470 PMID:14736747 regulation of transcription, DNA-dependent IEA InterPro:IPR000818 2290270 MGI:MGI:2152098 UniProtKB MGI:MGI:2152098 regulation of transcription, DNA-dependent IEA UniProtKB-KW:KW-0805 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 transcription, DNA-dependent IEA UniProtKB-KW:KW-0804 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 vasculogenesis IGI MGI:MGI:101876|MGI:MGI:103262 2290270 MGI:MGI:3773640|PMID:18332127 MGI MGI:MGI:3773640 PMID:18332127
1301622 Eae12_m susceptibility to experimental allergic encephalomyelitis 12 (mouse) Not determined 7 20365609 54365698 Mouse 1357714 Hdl38_m HDL level 38 (mouse) Not determined 7 20365609 54365698 Mouse 1301052 Bhr6_m bronchial hyperresponsiveness 6 (mouse) Not determined 7 20927844 54927961 Mouse 4141960 Rosq1_m reactive oxygen species QTL 1 (mouse) Not determined 7 30279833 64279979 Mouse 1301711 Tbrs3_m tuberculosis resistance 3 (mouse) Not determined 7 30287212 64287356 Mouse 4141204 Wtlr4_m weight loss response 4 (mouse) Not determined 7 30287212 64287356 Mouse 1301709 Bdt4_m bone density traits 4 (mouse) Not determined 7 30494518 64494662 Mouse 1357445 Dyscalc1_m dystrophic cardiac calcinosis 1 (mouse) Not determined 7 35942350 69942472 Mouse 1558814 Ducm1_m dsRNA-induced UCM 1 (mouse) Not determined 7 39320467 73320699 Mouse 1301175 Ap7q_m alcohol preference 7 QTL (mouse) Not determined 7 39320467 73320699 Mouse 4141059 Ciaaq1_m collagen induced arthritis autoantibody QTL 1 (mouse) Not determined 7 40000154 74000303 Mouse 1300996 Aorls2_m aortic lesion size 2 (mouse) Not determined 7 40000154 74000303 Mouse 1559000 Ossc1_m osteosarcoma susceptibility 1 (mouse) Not determined 7 41658647 75658845 Mouse 4142288 Mcvq1_m mean corpuscular volume QTL 1 (mouse) Not determined 7 42053491 76053640 Mouse 1300757 Cocia9_m cocaine induced activation 9 (mouse) Not determined 7 42053491 76053640 Mouse 1357586 Mdmsc3_m modifier of muscularity 3 (mouse) Not determined 7 42053491 76053640 Mouse 1300878 Skts1_m skin tumor susceptibility 1 (mouse) Not determined 7 45497008 79497204 Mouse 1357724 Fmgty6_m femur geometry 6 (mouse) Not determined 7 48754442 82754587 Mouse 4141929 Chlq18_m circulating hormone level QTL 18 (mouse) Not determined 7 48754442 82754587 Mouse 1559023 Gbrln_m granular brain lesions (mouse) Not determined 7 48754442 82754587 Mouse