Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gtf3c4 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | GTF3C4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of GTF3C4 mRNA | CTD | PMID:22079256 | Gtf3c4 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Gtf3c4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GTF3C4 mRNA | CTD | PMID:36331819 | Gtf3c4 | Rat | 17beta-estradiol | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Estradiol results in increased expression of GTF3C4 mRNA | CTD | PMID:23019147 and PMID:31614463 | Gtf3c4 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of GTF3C4 mRNA | CTD | PMID:32145629 | Gtf3c4 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Gtf3c4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GTF3C4 mRNA | CTD | PMID:21570461 | Gtf3c4 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Gtf3c4 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of GTF3C4 protein | CTD | PMID:31675489 | Gtf3c4 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of GTF3C4 mRNA | CTD | PMID:26251327 | Gtf3c4 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of GTF3C4 mRNA | CTD | PMID:31881176 | Gtf3c4 | Rat | aflatoxin B1 | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of GTF3C4 mRNA | CTD | PMID:19770486 | Gtf3c4 | Rat | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of GTF3C4 mRNA | CTD | PMID:33354967 | Gtf3c4 | Rat | aflatoxin B1 | increases methylation | ISO | GTF3C4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of GTF3C4 gene | CTD | PMID:27153756 | Gtf3c4 | Rat | all-trans-retinoic acid | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GTF3C4 mRNA | CTD | PMID:33167477 | Gtf3c4 | Rat | arsane | affects methylation | ISO | GTF3C4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GTF3C4 gene | CTD | PMID:25304211 | Gtf3c4 | Rat | arsenic atom | affects methylation | ISO | GTF3C4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GTF3C4 gene | CTD | PMID:25304211 | Gtf3c4 | Rat | arsenite(3-) | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | arsenite results in increased expression of GTF3C4 protein | CTD | PMID:37955338 | Gtf3c4 | Rat | benzo[a]pyrene | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of GTF3C4 mRNA | CTD | PMID:20064835 | Gtf3c4 | Rat | benzo[a]pyrene | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of GTF3C4 mRNA | CTD | PMID:22228805 | Gtf3c4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GTF3C4 mRNA | CTD | PMID:25181051 | Gtf3c4 | Rat | bisphenol A | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GTF3C4 protein | CTD | PMID:31675489 | Gtf3c4 | Rat | bisphenol A | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of GTF3C4 mRNA | CTD | PMID:33221593 | Gtf3c4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of GTF3C4 mRNA | CTD | PMID:32145629 | Gtf3c4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GTF3C4 mRNA | CTD | PMID:30816183 more ... | Gtf3c4 | Rat | bisphenol F | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | bisphenol F results in increased expression of GTF3C4 mRNA | CTD | PMID:38685157 | Gtf3c4 | Rat | cadmium dichloride | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of GTF3C4 mRNA | CTD | PMID:26472689 | Gtf3c4 | Rat | cadmium dichloride | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of GTF3C4 mRNA | CTD | PMID:38568856 | Gtf3c4 | Rat | CGP 52608 | multiple interactions | ISO | GTF3C4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GTF3C4 gene] | CTD | PMID:28238834 | Gtf3c4 | Rat | chlorpyrifos | decreases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of GTF3C4 mRNA | CTD | PMID:37019170 | Gtf3c4 | Rat | cobalt dichloride | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of GTF3C4 mRNA | CTD | PMID:19320972 | Gtf3c4 | Rat | copper(II) sulfate | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of GTF3C4 mRNA | CTD | PMID:19549813 | Gtf3c4 | Rat | coumarin | affects phosphorylation | ISO | GTF3C4 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of GTF3C4 protein | CTD | PMID:35688186 | Gtf3c4 | Rat | crotonaldehyde | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | 2-butenal results in decreased expression of GTF3C4 mRNA | CTD | PMID:20471460 | Gtf3c4 | Rat | decabromodiphenyl ether | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of GTF3C4 protein | CTD | PMID:31675489 | Gtf3c4 | Rat | Dibutyl phosphate | affects expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of GTF3C4 mRNA | CTD | PMID:37042841 | Gtf3c4 | Rat | ethanol | affects splicing | ISO | Gtf3c4 (Mus musculus) | 6480464 | Ethanol affects the splicing of GTF3C4 mRNA | CTD | PMID:30319688 | Gtf3c4 | Rat | FR900359 | affects phosphorylation | ISO | GTF3C4 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of GTF3C4 protein | CTD | PMID:37730182 | Gtf3c4 | Rat | ivermectin | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of GTF3C4 protein | CTD | PMID:32959892 | Gtf3c4 | Rat | methyl methanesulfonate | decreases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of GTF3C4 mRNA | CTD | PMID:23649840 | Gtf3c4 | Rat | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of GTF3C4 protein | CTD | PMID:33146391 | Gtf3c4 | Rat | paracetamol | affects expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of GTF3C4 mRNA | CTD | PMID:17562736 | Gtf3c4 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Gtf3c4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GTF3C4 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of GTF3C4 mRNA | CTD | PMID:36331819 | Gtf3c4 | Rat | phenobarbital | affects expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of GTF3C4 mRNA | CTD | PMID:19159669 | Gtf3c4 | Rat | phenol | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Phenol results in increased expression of GTF3C4 mRNA | CTD | PMID:17547211 | Gtf3c4 | Rat | pirinixic acid | multiple interactions | ISO | GTF3C4 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GTF3C4 mRNA | CTD | PMID:19710929 | Gtf3c4 | Rat | potassium chromate | multiple interactions | ISO | GTF3C4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of GTF3C4 mRNA | CTD | PMID:22079256 | Gtf3c4 | Rat | potassium chromate | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of GTF3C4 mRNA | CTD | PMID:22079256 | Gtf3c4 | Rat | silicon dioxide | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of GTF3C4 mRNA | CTD | PMID:25895662 | Gtf3c4 | Rat | sunitinib | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of GTF3C4 mRNA | CTD | PMID:31533062 | Gtf3c4 | Rat | titanium dioxide | increases methylation | ISO | Gtf3c4 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of GTF3C4 gene | CTD | PMID:35295148 | Gtf3c4 | Rat | titanium dioxide | decreases methylation | ISO | Gtf3c4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of GTF3C4 gene | CTD | PMID:35295148 | Gtf3c4 | Rat | triphenyl phosphate | affects expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GTF3C4 mRNA | CTD | PMID:37042841 | Gtf3c4 | Rat | triptonide | increases expression | ISO | Gtf3c4 (Mus musculus) | 6480464 | triptonide results in increased expression of GTF3C4 mRNA | CTD | PMID:33045310 | Gtf3c4 | Rat | valproic acid | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GTF3C4 mRNA | CTD | PMID:23179753 | Gtf3c4 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of GTF3C4 mRNA | CTD | PMID:23034163 | Gtf3c4 | Rat | zoledronic acid | increases expression | ISO | GTF3C4 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of GTF3C4 mRNA | CTD | PMID:20977926 | |