GTF3C4 (general transcription factor IIIC subunit 4) - Rat Genome Database

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Gene: GTF3C4 (general transcription factor IIIC subunit 4) Sus scrofa
Analyze
Symbol: GTF3C4
Name: general transcription factor IIIC subunit 4 (Ensembl:ral transcription factor IIIC subunit 4)
RGD ID: 13905674
Description: ENCODES a protein that exhibits histone acetyltransferase activity (inferred); RNA polymerase III general transcription initiation factor activity (inferred); INVOLVED IN chromatin remodeling (inferred); transcription initiation at RNA polymerase III promoter (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (inferred); nucleoplasm (inferred); transcription factor TFIIIC complex (inferred); INTERACTS WITH zearalenone
Type: protein-coding
RefSeq Status: MODEL
Previously known as: general transcription factor 3C polypeptide 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,454,503 - 272,479,952 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,454,488 - 272,479,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,486,784 - 306,512,281 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GTF3C4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,454,503 - 272,479,952 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,454,488 - 272,479,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,486,784 - 306,512,281 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GTF3C4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,670,035 - 132,694,955 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,670,035 - 132,694,953 (+)EnsemblGRCh38hg38GRCh38
GRCh379135,545,422 - 135,570,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,535,549 - 134,555,292 (+)NCBINCBI36Build 36hg18NCBI36
Build 349132,575,281 - 132,594,369NCBI
Celera9106,087,467 - 106,107,210 (+)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,039,470 - 105,059,183 (+)NCBIHuRef
CHM1_19135,696,098 - 135,715,832 (+)NCBICHM1_1
T2T-CHM13v2.09144,881,255 - 144,906,173 (+)NCBIT2T-CHM13v2.0
Gtf3c4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,712,311 - 28,730,628 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,712,311 - 28,730,372 (-)EnsemblGRCm39 Ensembl
GRCm38228,822,299 - 28,840,360 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,822,299 - 28,840,360 (-)EnsemblGRCm38mm10GRCm38
MGSCv37228,677,819 - 28,695,880 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,647,584 - 28,662,295 (-)NCBIMGSCv36mm8
Celera228,528,198 - 28,546,259 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Gtf3c4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,552,773 - 32,570,705 (-)NCBIGRCr8
mRatBN7.2312,154,803 - 12,172,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl312,154,805 - 12,172,725 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,230,694 - 15,245,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,815,662 - 23,830,729 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0322,070,107 - 22,085,174 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,404,857 - 7,422,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,404,841 - 7,422,738 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,752,411 - 12,773,005 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,834,130 - 7,849,247 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera36,937,372 - 6,952,433 (-)NCBICelera
Cytogenetic Map3p12NCBI
Gtf3c4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,037,312 - 2,054,451 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,037,312 - 2,054,451 (+)NCBIChiLan1.0ChiLan1.0
GTF3C4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,664,038 - 6,688,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,666,376 - 6,690,797 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09103,787,645 - 103,812,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,418,347 - 132,443,106 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,418,653 - 132,437,082 (+)Ensemblpanpan1.1panPan2
GTF3C4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,602,025 - 51,630,139 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,606,235 - 51,630,637 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,866,756 - 50,894,811 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,496,896 - 52,523,099 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,501,105 - 52,523,084 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,275,219 - 51,303,083 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,599,742 - 51,627,625 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,679,349 - 51,707,219 (-)NCBIUU_Cfam_GSD_1.0
Gtf3c4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,415,069 - 199,433,889 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648719,183,596 - 19,202,407 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF3C4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,447,644 - 5,468,043 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,448,494 - 5,468,334 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,171,044 - 10,196,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf3c4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,673,769 - 3,692,407 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,666,442 - 3,692,077 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GTF3C4
1057 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006302   ⟹   ENSSSCP00000006140
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1272,454,503 - 272,479,952 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000095871   ⟹   ENSSSCP00000078318
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1272,454,614 - 272,479,952 (+)Ensembl
RefSeq Acc Id: XM_001929441   ⟹   XP_001929476
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11272,454,488 - 272,479,968 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001929476   ⟸   XM_001929441
- UniProtKB: A0A480RX43 (UniProtKB/TrEMBL),   A0A4X1T3V7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000006140   ⟸   ENSSSCT00000006302
RefSeq Acc Id: ENSSSCP00000078318   ⟸   ENSSSCT00000095871
Protein Domains
DUF5921   Transcription factor IIIC 90kDa subunit N-terminal   Transcription factor IIIC putative zinc-finger


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005731 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005006742 UniProtKB/TrEMBL
  ENSSSCG00015061869 UniProtKB/TrEMBL
  ENSSSCG00025051891 UniProtKB/TrEMBL
  ENSSSCG00030044637 UniProtKB/TrEMBL
  ENSSSCG00035028296 UniProtKB/TrEMBL
  ENSSSCG00040008617 UniProtKB/TrEMBL
  ENSSSCG00045028100 UniProtKB/TrEMBL
  ENSSSCG00065001098 UniProtKB/TrEMBL
  ENSSSCG00070006653 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006302.5 UniProtKB/TrEMBL
  ENSSSCT00000095871 ENTREZGENE
  ENSSSCT00000095871.1 UniProtKB/TrEMBL
  ENSSSCT00005010231.1 UniProtKB/TrEMBL
  ENSSSCT00015082652.1 UniProtKB/TrEMBL
  ENSSSCT00025070949.1 UniProtKB/TrEMBL
  ENSSSCT00030062250.1 UniProtKB/TrEMBL
  ENSSSCT00035037415.1 UniProtKB/TrEMBL
  ENSSSCT00040011217.1 UniProtKB/TrEMBL
  ENSSSCT00045047863.1 UniProtKB/TrEMBL
  ENSSSCT00065001319.1 UniProtKB/TrEMBL
  ENSSSCT00070012751.1 UniProtKB/TrEMBL
InterPro DUF5921 UniProtKB/TrEMBL
  GTF3C4 UniProtKB/TrEMBL
  TFIIIC_delta_N UniProtKB/TrEMBL
  TFIIIC_Znf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100157514 UniProtKB/TrEMBL
NCBI Gene GTF3C4 ENTREZGENE
PANTHER GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 UniProtKB/TrEMBL
  PTHR15496 UniProtKB/TrEMBL
Pfam DUF5921 UniProtKB/TrEMBL
  TFIIIC_delta UniProtKB/TrEMBL
  zf-TFIIIC UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A480RX43 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T3V7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FJ34_PIG UniProtKB/TrEMBL
  F1S0S8_PIG UniProtKB/TrEMBL
UniProt Secondary A0A8D0IAK1 UniProtKB/TrEMBL
VGNC ID VGNC:88740 ENTREZGENE