Cbx4 (chromobox 4) - Rat Genome Database

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Gene: Cbx4 (chromobox 4) Rattus norvegicus
Analyze
Symbol: Cbx4
Name: chromobox 4
RGD ID: 1587243
Description: Predicted to enable several functions, including SUMO binding activity; SUMO ligase activity; and phosphoprotein binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and protein sumoylation. Predicted to be located in nuclear body. Predicted to be part of PRC1 complex. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CBX4 (chromobox 4); PARTICIPATES IN histone modification pathway; INTERACTS WITH alpha-Zearalanol; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); chromobox homolog 4 (Pc class homolog, Drosophila); E3 SUMO-protein ligase CBX4; LOC501403; similar to Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (MPc2)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810104,835,685 - 104,841,727 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl10104,835,685 - 104,841,727 (-)EnsemblGRCr8
mRatBN7.210104,337,140 - 104,343,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,336,876 - 104,356,706 (-)EnsemblmRatBN7.2
Rnor_6.010108,190,947 - 108,196,455 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,190,995 - 108,196,217 (-)Ensemblrn6Rnor6.0
Rnor_5.010107,803,761 - 107,809,306 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera10102,881,315 - 102,890,183 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
depsipeptide  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diethyl maleate  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propan-2-ol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tetrachloromethane  (EXP)
thifluzamide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
XL147  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear body  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
PcG protein complex  (IEA,ISO)
PRC1 complex  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
3. Polycomb chromobox 4 enhances migration and pulmonary metastasis of hepatocellular carcinoma cell line MHCC97L. Mei Z, etal., Sci China Life Sci. 2014 Jun;57(6):610-7. doi: 10.1007/s11427-014-4663-9. Epub 2014 May 16.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
8. Chromobox homolog 4 is correlated with prognosis and tumor cell growth in hepatocellular carcinoma. Wang B, etal., Ann Surg Oncol. 2013 Dec;20 Suppl 3:S684-92. doi: 10.1245/s10434-013-3171-7. Epub 2013 Aug 14.
Additional References at PubMed
PMID:9367786   PMID:12167701   PMID:12679040   PMID:16537902   PMID:17087506   PMID:17392792   PMID:17439403   PMID:18555800   PMID:18567530   PMID:19636380   PMID:20098713   PMID:20176810  
PMID:20417598   PMID:21282530   PMID:22082260   PMID:35880565  


Genomics

Comparative Map Data
Cbx4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810104,835,685 - 104,841,727 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl10104,835,685 - 104,841,727 (-)EnsemblGRCr8
mRatBN7.210104,337,140 - 104,343,210 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,336,876 - 104,356,706 (-)EnsemblmRatBN7.2
Rnor_6.010108,190,947 - 108,196,455 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,190,995 - 108,196,217 (-)Ensemblrn6Rnor6.0
Rnor_5.010107,803,761 - 107,809,306 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera10102,881,315 - 102,890,183 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
CBX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381779,833,156 - 79,839,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1779,833,156 - 79,839,469 (-)Ensemblhg38GRCh38
GRCh371777,806,955 - 77,813,239 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361775,421,550 - 75,427,808 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341775,421,550 - 75,427,808NCBI
Celera1774,433,438 - 74,439,695 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1773,247,786 - 73,258,221 (-)NCBIHuRef
CHM1_11777,893,186 - 77,899,450 (-)NCBICHM1_1
T2T-CHM13v2.01780,730,965 - 80,737,249 (-)NCBIT2T-CHM13v2.0
Cbx4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911118,968,399 - 118,977,067 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11118,968,399 - 118,977,047 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3811119,077,571 - 119,086,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11119,077,573 - 119,086,221 (-)Ensemblmm10GRCm38
MGSCv3711118,938,885 - 118,947,551 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611118,896,245 - 118,902,231 (-)NCBIMGSCv36mm8
Celera11130,821,957 - 130,830,758 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.34NCBI
Cbx4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555062,998,237 - 3,002,788 (+)Ensembl
ChiLan1.0NW_0049555062,998,241 - 3,002,788 (+)NCBIChiLan1.0ChiLan1.0
CBX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21995,887,592 - 95,893,876 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117100,716,535 - 100,722,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01773,913,264 - 73,919,540 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11779,450,190 - 79,458,866 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1779,449,919 - 79,458,866 (-)EnsemblpanPan2panpan1.1
CBX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.191,799,847 - 1,807,500 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl91,802,047 - 1,807,690 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha92,441,071 - 2,447,341 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.092,433,610 - 2,439,872 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl92,433,687 - 2,440,062 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.192,456,843 - 2,463,104 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.092,582,319 - 2,588,578 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.092,663,556 - 2,669,818 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cbx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056022,461,814 - 2,468,024 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365943,943,924 - 3,950,196 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365943,943,933 - 3,950,124 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl122,521,027 - 2,527,241 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1122,520,913 - 2,527,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2122,591,117 - 2,597,525 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11671,795,919 - 71,802,184 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1671,795,862 - 71,802,051 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607743,093,037 - 43,099,314 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbx4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248019,003,059 - 9,008,203 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248019,002,290 - 9,008,305 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cbx4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1964,947,708 - 64,954,570 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cbx4
26 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:66
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000075440
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093723381107556066Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1089039175107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1097202388107556066Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087807758107713808Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1091127270107556066Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091727883107713808Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1097202388107556066Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000075440   ⟹   ENSRNOP00000066624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10108,190,995 - 108,196,217 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115792   ⟹   ENSRNOP00000091742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl10104,835,685 - 104,841,727 (-)Ensembl
mRatBN7.2 Ensembl10104,336,876 - 104,356,706 (-)Ensembl
RefSeq Acc Id: NM_001427455   ⟹   NP_001414384
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810104,835,685 - 104,841,727 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414384 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM06774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000091742
  ENSRNOP00000091742.1
Ensembl Acc Id: ENSRNOP00000066624   ⟸   ENSRNOT00000075440
Ensembl Acc Id: ENSRNOP00000091742   ⟸   ENSRNOT00000115792
RefSeq Acc Id: NP_001414384   ⟸   NM_001427455
- UniProtKB: A0A8I6ACN6 (UniProtKB/TrEMBL)
Protein Domains
Chromo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RAR7-F1-model_v2 AlphaFold M0RAR7 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1587243 AgrOrtholog
BioCyc Gene G2FUF-22506 BioCyc
Ensembl Genes ENSRNOG00000046207 Ensembl
  ENSRNOG00000063043 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000115792 ENTREZGENE
  ENSRNOT00000115792.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
InterPro CBX4 UniProtKB/TrEMBL
  CBX7_C UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/TrEMBL
  Chromo/chromo_shadow_dom UniProtKB/TrEMBL
  Chromo_dom_subgr UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
NCBI Gene 501403 ENTREZGENE
PANTHER E3 SUMO-PROTEIN LIGASE CBX4 UniProtKB/TrEMBL
  PTHR46727 UniProtKB/TrEMBL
Pfam CBX7_C UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
PhenoGen Cbx4 PhenoGen
PRINTS CHROMODOMAIN UniProtKB/TrEMBL
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046207 RatGTEx
  ENSRNOG00000063043 RatGTEx
SMART CHROMO UniProtKB/TrEMBL
Superfamily-SCOP SSF54160 UniProtKB/TrEMBL
UniProt A0A8I6ACN6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Cbx4  chromobox 4  Cbx4  chromobox 4  Data merged from RGD:149736183 737654 PROVISIONAL
2021-08-09 Cbx4  chromobox 4      Symbol and Name status set to provisional 45752 PROVISIONAL
2015-12-02 Cbx4  chromobox 4  Cbx4  chromobox homolog 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-29 Cbx4  chromobox homolog 4  Cbx4  chromobox homolog 4 (Pc class homolog, Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Cbx4  chromobox homolog 4 (Pc class homolog, Drosophila)  Cbx4  chromobox homolog 4 (Drosophila Pc class)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Cbx4  chromobox homolog 4 (Drosophila Pc class)  LOC501403  similar to Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (MPc2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC501403  similar to Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (MPc2)      Symbol and Name status set to provisional 70820 PROVISIONAL