QTL: Cia5 (Collagen induced arthritis QTL 5) Rattus norvegicus Symbol: Cia5 Name: Collagen induced arthritis QTL 5 Also known as: Type II Collagen induced arthritis QTL 5 Trait: Joint/bone inflammation Subtrait: type II collagen induced Method: arthritis severity was measured via a scoring system for cartilage surface area and joint size; joints were measured twice weekly for six weeks following type II collagen injection LOD Score: 4.9 P Value: Not Available Variance: Not Available Position Map Chr Position Strand Source RGSC Genome Assembly v5.0 10 94,237,414 - 107,484,761   RGD RGSC Genome Assembly v3.4 10 95,692,240 - 140,692,240   RGD Genome Assembly 3.1 10 95,708,476 - 110,733,352   RGD Cross Type: F2 Strains Crossed: F344/NHsd DA/Bkl  Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Candidate Gene Status Prkca is a candidate Gene for Cia5 Timp2 is a candidate Gene for Cia5 Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Arthritis, Rheumatoid   IED   61062   RGD   Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) joint inflammation   QTM   61062   RGD   joint swelling   QTM   61062   RGD   Disease Annotations Arthritis, Rheumatoid  (IED) Phenotype Annotations joint inflammation  (QTM) joint swelling  (QTM) References - curated 1. Brenner M, etal., Mol Med. 2007 May-Jun;13(5-6):277-87. 2. Dahlman I, etal., Eur J Immunol 1998 Jul;28(7):2188-96 3. Joe B Physiol Genomics. 2006 Oct 3;27(1):1-11. Epub 2006 Jun 27. 4. Remmers EF, etal., Nat Genet 1996 Sep;14(1):82-5 5. Xiong Q, etal., J Immunol. 2008 Jul 15;181(2):859-64. RGD Disease Portals Cia5 has been annotated in the following RGD Disease Portals. Immune and Inflammatory Diseases Immune and Inflammatory Phenotypes Related QTLs Related QTL Description Reference Pia10 maps to same region RGD:61519 Aia5 interacts with RGD:625379 Cia23 interacts with RGD:631168 Cia22 interacts with RGD:631168 Cia21 interacts with RGD:631168 Cia20 interacts with RGD:631168 Eau3 maps to same region RGD:61073 Cari1 maps to same region RGD:69693 Region Genes in Region (RGSC Genome Assembly v3.4) The following Genes overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name Chr Start Stop Species 2686 Gh1 growth hormone 1 10 95692240 95694117 Rat 620012 Cd79b Cd79b molecule, immunoglobulin-associated beta 10 95703129 95706275 Rat 3636 Scn4a sodium channel, voltage-gated, type IV, alpha subunit 10 95710710 95760323 Rat 1307288 RGD1307288 similar to Protein C17orf72 10 95769680 95772074 Rat 1359660 Icam2 intercellular adhesion molecule 2 10 95772448 95779071 Rat 1559716 Ern1 endoplasmic reticulum to nucleus signaling 1 10 95794488 95855895 Rat 1586412 LOC688688 similar to ribosomal protein S10 10 95866818 95867307 Rat 1305112 Tex2 testis expressed 2 10 95938743 96002144 Rat 61927 Pecam1 platelet/endothelial cell adhesion molecule 1 10 96056220 96057232 Rat 620488 Milr1 mast cell immunoglobulin-like receptor 1 10 96110944 96111829 Rat 1305128 Polg2 polymerase (DNA directed), gamma 2, accessory subunit 10 96120205 96130221 Rat 619906 Ddx5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 10 96131888 96139423 Rat 1309655 Cep95 centrosomal protein 95kDa 10 96139324 96168887 Rat 1310067 Smurf2 SMAD specific E3 ubiquitin protein ligase 2 10 96170590 96269365 Rat 1585220 LOC688788 hypothetical protein LOC688788 10 96268683 96273352 Rat 2323039 LOC100363406 hypothetical LOC100363406 10 96277953 96278710 Rat 621419 Kpna2 karyopherin alpha 2 10 96342214 96352613 Rat 1584120 LOC688846 hypothetical protein LOC688846 10 96365945 96384078 Rat 1565033 RGD1565033 similar to hypothetical protein LOC284018 isoform b 10 96383794 96385947 Rat 1307039 Falz fetal Alzheimer antigen 10 96391087 96402832 Rat 1584081 Nol11 nucleolar protein 11 10 96556787 96569562 Rat 1562577 RGD1562577 similar to gamma non-muscle actin 10 96570098 96571621 Rat 1597047 Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 10 96594391 96871091 Rat 1585285 LOC688722 similar to Male-enhanced antigen 1 (Mea-1) 10 96660791 96661314 Rat 1359290 RGD1359290 Ribosomal_L22 domain containing protein RGD1359290 10 96796306 96819928 Rat 1582971 LOC688936 similar to ribosomal protein S23 10 96877374 96877804 Rat 1359305 Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 10 96881373 96907258 Rat 1307049 Helz helicase with zinc finger 10 96952234 97091028 Rat 2249 Cacng1 calcium channel, voltage-dependent, gamma subunit 1 10 97105707 97118400 Rat 628804 Cacng4 calcium channel, voltage-dependent, gamma subunit 4 10 97139397 97214444 Rat 628805 Cacng5 calcium channel, voltage-dependent, gamma subunit 5 10 97300594 97309023 Rat 3395 Prkca protein kinase C, alpha 10 97367196 97638910 Rat 1310625 Apoh apolipoprotein H (beta-2-glycoprotein I) 10 97725088 97739213 Rat 1561210 RGD1561210 similar to Rpl7a protein 10 97743684 97747617 Rat 1564168 Cep112 centrosomal protein 112kDa 10 97749014 98220467 Rat 69259 Axin2 axin 2 10 98294466 98321830 Rat 2323295 LOC100359847 hypothetical LOC100359847 10 98506787 98513257 Rat 1597401 LOC689085 hypothetical protein LOC689085 10 98575026 98575678 Rat 1565459 RGD1565459 similar to ribosomal protein L10a 10 98593458 98593826 Rat 3572 Rgs9 regulator of G-protein signaling 9 10 98598326 98647948 Rat 1307754 Wipi1 WD repeat domain, phosphoinositide interacting 1 10 98722266 98753713 Rat 1306571 Arsg arylsulfatase G 10 98754633 98833808 Rat 2321294 LOC100360864 hypothetical protein LOC100360864 10 98835885 98852404 Rat 735117 Slc16a6 solute carrier family 16, member 6 (monocarboxylic acid transporter 7) 10 98853289 98875189 Rat 1304846 Amz2 archaelysin family metallopeptidase 2 10 98889302 98899839 Rat 1310221 Gna13 guanine nucleotide binding protein (G protein), alpha 13 10 98933205 98965819 Rat 1306364 Fam20a family with sequence similarity 20, member A 10 99113846 99170601 Rat 1559578 RGD1559578 RGD1559578 10 99245447 99278725 Rat 1587319 LOC363694 hypothetical LOC363694 10 99390939 99391404 Rat 1307069 Abca8 ATP-binding cassette, subfamily A (ABC1), member 8 10 99392053 99452833 Rat 1307333 Abca8a ATP-binding cassette, subfamily A (ABC1), member 8a 10 99477700 99544364 Rat 1305931 Abca9 ATP-binding cassette, subfamily A (ABC1), member 9 10 99558803 99619870 Rat 1308998 Abca6 ATP-binding cassette, subfamily A (ABC1), member 6 10 99626334 99693870 Rat 628661 Abca5 ATP-binding cassette, subfamily A (ABC1), member 5 10 99724778 99793593 Rat 620666 Map2k6 mitogen-activated protein kinase kinase 6 10 99859684 99974446 Rat 1587318 LOC363695 similar to CDK105 protein 10 100439847 100440636 Rat 61824 Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 10 100514180 100515949 Rat 61968 Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 10 100574985 100576268 Rat 1591122 LOC689505 hypothetical protein LOC689505 10 100837924 100838818 Rat 1591114 LOC689513 hypothetical protein LOC689513 10 101046142 101191968 Rat 2323140 LOC100359904 hypothetical LOC100359904 10 101228877 101229419 Rat 1565086 RGD1565086 similar to ubiquitin-conjugating enzyme E2C 10 101603675 101604205 Rat 1589964 LOC689614 hypothetical protein LOC689614 10 102095745 102116855 Rat 1589929 LOC689649 similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a) 10 102220373 102232626 Rat 620474 Sox9 SRY (sex determining region Y)-box 9 10 102392187 102394256 Rat 1589896 LOC689682 hypothetical protein LOC689682 10 102681539 102682182 Rat 1311981 Slc39a11 solute carrier family 39 (metal ion transporter), member 11 10 102863399 103189081 Rat 3763 Sstr2 somatostatin receptor 2 10 103246880 103254444 Rat 1304594 Cog1 component of oligomeric golgi complex 1 10 103279513 103292311 Rat 1563409 Fam104a family with sequence similarity 104, member A 10 103291220 103312198 Rat 1359207 MGC95210 hypothetical LOC287798 10 103311635 103322562 Rat 1306397 Cpsf4l cleavage and polyadenylation specific factor 4-like 10 103327521 103339565 Rat 1588736 LOC689752 similar to Cdc42 effector protein 4 (Binder of Rho GTPases 4) 10 103357114 103358982 Rat 1311567 Cdc42ep4 CDC42 effector protein (Rho GTPase binding) 4 10 103365895 103390663 Rat 2320553 LOC100361210 hypothetical protein LOC100361210 10 103368109 103389742 Rat 1565238 RGD1565238 similar to glyceraldehyde-3-phosphate dehydrogenase 10 103407984 103408985 Rat 1310397 Sdk2 sidekick cell adhesion molecule 2 10 103422675 103699967 Rat 1305573 Rpl38 ribosomal protein L38 10 104545644 104549279 Rat 1562969 Ttyh2 tweety homolog 2 (Drosophila) 10 104553284 104596673 Rat 1359602 Dnai2 dynein, axonemal, intermediate chain 2 10 104606688 104641181 Rat 1559936 Kif19 kinesin family member 19 10 104648142 104674120 Rat 1563331 Btbd17 BTB (POZ) domain containing 17 10 104674002 104680503 Rat 1559926 Gpr142 G protein-coupled receptor 142 10 104682427 104691618 Rat 1311408 Gprc5c G protein-coupled receptor, family C, group 5, member C 10 104731909 104754468 Rat 1583719 Cd300a Cd300a molecule 10 104775860 104789151 Rat 1583718 Cd300lb CD300 molecule-like family member b 10 104825709 104835698 Rat 1559458 RGD1559458 similar to Immunoglobulin superfamily, member 7 10 104854344 104858923 Rat 1562156 RGD1562156 similar to MAIR-IIb 10 104906025 104910379 Rat 2320083 LOC100361482 Cd300 molecule-like family member D-like 10 104921846 104927838 Rat 2319928 LOC100361539 immune activating receptor Cd300d1-like 10 104933549 104939608 Rat 2319883 Cd300ldl CD300 molecule-like family member d-like 10 104948159 104951724 Rat 2319739 Cd300ld Cd300 molecule-like family member D 10 104962447 104965459 Rat 1565046 RGD1565046 similar to CLM6 10 104971597 104975333 Rat 1562667 RGD1562667 similar to leukocyte mono-Ig-like receptor2 10 104986719 104990056 Rat 2319527 LOC100361747 CLM3 10 104994828 105000874 Rat 1564512 RGD1564512 similar to solute carrier family 25, member 5 10 105003434 105004330 Rat 1559482 RGD1559482 similar to immunoglobulin superfamily, member 7 10 105006561 105011256 Rat 1563057 RGD1563057 similar to Immunoglobulin superfamily, member 7 10 105016892 105032096 Rat 1565161 RGD1565161 similar to dendritic cell-derived immunoglobulin(Ig)-like receptor 1, DIgR1 - mouse 10 105034719 105061415 Rat 1561778 RGD1561778 similar to dendritic cell-derived immunoglobulin(Ig)-like receptor 1, DIgR1 - mouse 10 105084608 105089307 Rat 1560640 RGD1560640 similar to solute carrier family 25, member 5 10 105091578 105092468 Rat 1305426 Cd300le Cd300 molecule-like family member E 10 105102015 105111669 Rat 1585137 Cd300e Cd300e molecule 10 105122684 105130558 Rat 1586145 LOC363703 similar to 60S ribosomal protein L6 (TAX-responsive enhancer element-binding protein 107) (TAXREB107) (Neoplasm-related protein C140) 10 105130872 105133795 Rat 1304742 Rab37 RAB37, member of RAS oncogene family 10 105166256 105235098 Rat 1309733 Cd300lf Cd300 molecule-like family member F 10 105192308 105209016 Rat 708538 Slc9a3r1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 10 105237637 105254750 Rat 1307096 Nat9 N-acetyltransferase 9 (GCN5-related, putative) 10 105256791 105261562 Rat 1307953 Tmem104 transmembrane protein 104 10 105261751 105318174 Rat 2739 Grin2c glutamate receptor, ionotropic, N-methyl D-aspartate 2C 10 105323371 105340976 Rat 621648 Fdxr ferredoxin reductase 10 105342684 105351374 Rat 1311950 Fads6 fatty acid desaturase 6 10 105357799 105373626 Rat 1304551 Ush1g Usher syndrome 1G 10 105395184 105399053 Rat 1304830 Otop2 otopetrin 2 10 105400190 105409760 Rat 1306663 Otop3 otopetrin 3 10 105412853 105423998 Rat 1311422 Hid1 HID1 domain containing 10 105424827 105445183 Rat 1306881 Cdr2l cerebellar degeneration-related protein 2-like 10 105460482 105472167 Rat 620083 Atp5h ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10 105474107 105499413 Rat 1307942 Ict1 immature colon carcinoma transcript 1 10 105481865 105488361 Rat 1584001 LOC690171 similar to H3 histone, family 3B 10 105490835 105493744 Rat 1566063 Kctd2 potassium channel tetramerisation domain containing 2 10 105499682 105510985 Rat 1311352 Trim47l tripartite motif protein 47-like 10 105519570 105527580 Rat 1582896 Slc16a5 solute carrier family 16, member 5 (monocarboxylic acid transporter 6) 10 105543856 105556494 Rat 1310043 Armc7 armadillo repeat containing 7 10 105558266 105574799 Rat 2321875 LOC100360582 5',3'-nucleotidase, cytosolic 10 105574754 105576848 Rat 1359325 Hn1 hematological and neurological expressed 1 10 105579880 105598071 Rat 621761 Sumo2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 10 105608097 105620455 Rat 1311942 Nup85 nucleoporin 85 10 105645505 105665079 Rat 1309553 Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 10 105665476 105684513 Rat 1309164 Mrps7 mitochondrial ribosomal protein S7 10 105683558 105687212 Rat 1309685 Mif4gd MIF4G domain containing 10 105687220 105691684 Rat 1359554 Slc25a19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 10 105694526 105707452 Rat 619758 Grb2 growth factor receptor bound protein 2 10 105722014 105818649 Rat 1587533 LOC689847 similar to High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30) 10 105805174 105806456 Rat 1597385 LOC690301 hypothetical protein LOC690301 10 105818137 105818898 Rat 2318703 LOC100362181 developmental pluripotency-associated 2 10 105819017 105822945 Rat 1309310 RGD1309310 similar to mKIAA0195 protein 10 105864841 105901797 Rat 1309738 Caskin2 cask-interacting protein 2 10 105901164 105915318 Rat 1597379 Tsen54 tRNA splicing endonuclease 54 homolog (S. cerevisiae) 10 105916407 105923991 Rat 1560307 Llgl2 lethal giant larvae homolog 2 (Drosophila) 10 105925312 105960550 Rat 1597365 LOC690323 similar to Myosin-15 (Myosin XV) (Unconventional myosin-15) 10 105994016 105999569 Rat 1310823 Recql5 RecQ protein-like 5 10 106000185 106039287 Rat 1586374 Smim5 small integral membrane protein 5 10 106007671 106013451 Rat 1565537 Sap30bp SAP30 binding protein 10 106039460 106070965 Rat 2321678 LOC100360679 ribosomal protein S18-like 10 106078153 106078661 Rat 2928 Itgb4 integrin, beta 4 10 106080452 106116632 Rat 1305375 Galk1 galactokinase 1 10 106116774 106120951 Rat 1591158 LOC688268 hypothetical protein LOC688268 10 106125276 106125815 Rat 621095 H3f3b H3 histone, family 3B 10 106130320 106132544 Rat 1309224 Unk unkempt homolog (Drosophila) 10 106139489 106169639 Rat 628593 Unc13d unc-13 homolog D (C. elegans) 10 106170475 106185215 Rat 620032 Wbp2 WW domain binding protein 2 10 106187124 106194374 Rat 1597317 Trim47 tripartite motif-containing 47 10 106211265 106215736 Rat 1559497 Trim65 tripartite motif-containing 65 10 106232274 106237808 Rat 1311180 Mrpl38 mitochondrial ribosomal protein L38 10 106238696 106245499 Rat 1310662 Fbf1 Fas (TNFRSF6) binding factor 1 10 106248236 106275749 Rat 619757 Acox1 acyl-CoA oxidase 1, palmitoyl 10 106281977 106319382 Rat 1311078 Ten1 TEN1 telomerase capping complex subunit 10 106318384 106327849 Rat 1591155 LOC688271 similar to Truncated cell division protein kinase 3 homolog 10 106328470 106331011 Rat 1306141 Evpl envoplakin 10 106336953 106353217 Rat 1305376 Srp68 signal recognition particle 68 10 106359742 106387284 Rat 2657 Galr2 galanin receptor 2 10 106394006 106396171 Rat 620236 Exoc7 exocyst complex component 7 10 106400889 106419793 Rat 1311298 Ubald2 UBA-like domain containing 2 10 106543188 106547768 Rat 1562974 Qrich2 glutamine rich 2 10 106549913 106578744 Rat 620206 Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 10 106582381 106604072 Rat 620048 Sphk1 sphingosine kinase 1 10 106641509 106645579 Rat 1310297 Ube2o ubiquitin-conjugating enzyme E2O 10 106646738 106694554 Rat 1559519 RGD1559519 similar to ribosomal protein L14 10 106705908 106706535 Rat 2006 Aanat aralkylamine N-acetyltransferase 10 106709371 106713683 Rat 1309699 Rhbdf2 rhomboid 5 homolog 2 (Drosophila) 10 106715043 106742198 Rat 69415 Cygb cytoglobin 10 106759885 106769651 Rat 1560747 St6galnac2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 10 106793126 106811346 Rat 1562048 St6galnac1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 10 106837311 106881619 Rat 1594666 Mxra7 matrix-remodelling associated 7 10 106905636 106921646 Rat 2324535 LOC100362519 thymosin, beta 10-like 10 106928922 106929047 Rat 1305395 Jmjd6 jumonji domain containing 6 10 106942942 106948652 Rat 1306284 Mettl23 methyltransferase like 23 10 106948784 106953448 Rat 1359422 Srsf2 serine/arginine-rich splicing factor 2 10 106954365 106956807 Rat 1307394 Mfsd11 major facilitator superfamily domain containing 11 10 106957529 106973225 Rat 1593422 LOC690647 hypothetical protein LOC690647 10 107019801 107020438 Rat 1305188 Mgat5b mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 10 107019869 107089319 Rat 1593404 LOC690667 hypothetical protein LOC690667 10 107202056 107221207 Rat 1563123 Sec14l1 SEC14-like 1 (S. cerevisiae) 10 107220734 107267940 Rat 708523 Sept9 septin 9 10 107343672 107479964 Rat 1310027 RGD1310027 similar to KIAA1582 protein 10 107829754 107854869 Rat 621087 Socs3 suppressor of cytokine signaling 3 10 107958468 107959330 Rat 1305052 Pgs1 phosphatidylglycerophosphate synthase 1 10 107978636 108009997 Rat 1563805 Dnah17 dynein, axonemal, heavy chain 17 10 108012773 108130864 Rat 620397 Cyth1 cytohesin 1 10 108189311 108253419 Rat 1309937 Usp36 ubiquitin specific peptidase 36 10 108264874 108296384 Rat 61312 Timp2 TIMP metallopeptidase inhibitor 2 10 108310473 108358821 Rat 1597046 Ddc8 differential display clone 8 10 108336344 108349394 Rat 620837 Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein 10 108388185 108397523 Rat 628743 Cant1 calcium activated nucleotidase 1 10 108405355 108420225 Rat 1359204 C1qtnf1 C1q and tumor necrosis factor related protein 1 10 108431984 108452099 Rat 1310868 Engase endo-beta-N-acetylglucosaminidase 10 108478622 108491272 Rat 1560070 Rbfox3 RNA binding protein, fox-1 homolog (C. elegans) 3 10 108492172 108635296 Rat 2324734 LOC100363156 signal recognition particle 19kDa-like 10 108608582 108609013 Rat 1306178 Slc26a11 solute carrier family 26, member 11 10 108730993 108741761 Rat 1308168 Rnf213 ring finger protein 213 10 108765490 108862935 Rat 1592173 LOC690798 similar to Mucin-5B precursor (Mucin 5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin) 10 108825297 108827557 Rat 1562414 LOC498029 similar to RIKEN cDNA A730011L01 gene 10 108867383 108882929 Rat 628894 Nptx1 neuronal pentraxin I 10 108918661 108927616 Rat 1306329 Polr2h-ps1 polymerase (RNA) II (DNA directed) polypeptide H, pseudogene 1 10 108968672 108969124 Rat 1311784 Rptor regulatory associated protein of MTOR, complex 1 10 109000666 109302700 Rat 1565325 Chmp6 charged multivesicular body protein 6 10 109317687 109323357 Rat 619814 Baiap2 BAI1-associated protein 2 10 109351201 109413703 Rat 1590980 Aatk apoptosis-associated tyrosine kinase 10 109419819 109456182 Rat 1307745 Azi1 5-azacytidine induced 1 10 109475085 109499448 Rat 1307410 Enthd2 ENTH domain containing 2 10 109503079 109510361 Rat 1590963 LOC690871 hypothetical protein LOC690871 10 109510635 109512782 Rat 1306356 Slc38a10 solute carrier family 38, member 10 10 109516004 109569804 Rat 1590947 LOC690889 hypothetical protein LOC690889 10 109655501 109658779 Rat 1306500 Bahcc1 BAH domain and coiled-coil containing 1 10 109726243 109735724 Rat 1304556 Actg1 actin, gamma 1 10 109773489 109776334 Rat 1308941 Fscn2 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) 10 109789092 109795631 Rat 1306926 RGD1306926 similar to hypothetical protein FLJ22175 10 109797992 109806963 Rat 620794 Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 10 109809121 109878278 Rat 69225 Hgs hepatocyte growth factor-regulated tyrosine kinase substrate 10 109861289 109869587 Rat 1588559 Mrpl12 mitochondrial ribosomal protein L12 10 109870160 109874664 Rat 621430 Slc25a10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 10 109877811 109885272 Rat 2669 Gcgr glucagon receptor 10 109921411 109929577 Rat 1311925 Fam195b family with sequence similarity 195, member B 10 109933593 109935644 Rat 1308861 Ppp1r27 protein phosphatase 1, regulatory subunit 27 10 109941604 109942773 Rat 3244 P4hb prolyl 4-hydroxylase, beta polypeptide 10 109950221 109961716 Rat 2319365 LOC100361809 H/ACA ribonucleoprotein complex subunit 3 10 109965338 109965544 Rat 1359547 Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 10 109967771 109971260 Rat 1594679 Thoc4 THO complex 4 10 109984500 109988263 Rat 1561880 Anapc11 anaphase promoting complex subunit 11 10 109988502 109999500 Rat 708513 Npb neuropeptide B 10 109999845 110000279 Rat 619970 Pcyt2 phosphate cytidylyltransferase 2, ethanolamine 10 110002023 110009335 Rat 1305876 Sirt7 sirtuin 7 10 110009669 110016346 Rat 619953 Mafg v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 10 110019741 110024927 Rat 1307863 Pycr1 pyrroline-5-carboxylate reductase 1 10 110030931 110035883 Rat 1588672 LOC691019 hypothetical protein LOC691019 10 110037274 110042886 Rat 1311499 Myadml2 myeloid-associated differentiation marker-like 2 10 110039330 110040967 Rat 1307119 Notum notum pectinacetylesterase homolog (Drosophila) 10 110047040 110054106 Rat 1588666 Aspscr1 alveolar soft part sarcoma chromosome region, candidate 1 (human) 10 110066265 110099230 Rat 620603 Slc16a3 solute carrier family 16, member 3 (monocarboxylic acid transporter 4) 10 110159679 110163182 Rat 71031 Csnk1d casein kinase 1, delta 10 110166244 110197233 Rat 1310015 Cd7 Cd7 molecule 10 110250174 110253055 Rat 1588637 LOC691061 hypothetical protein LOC691061 10 110269446 110271013 Rat 735132 Sectm1b secreted and transmembrane 1B 10 110271328 110279893 Rat 1305973 Sectm1 secreted and transmembrane 1 10 110283747 110294733 Rat 1588608 Tex19.2 testis expressed gene 19.2 10 110325885 110353003 Rat 1566280 Tex19.1 testis expressed 19.1 10 110376944 110379146 Rat 621884 Uts2r urotensin 2 receptor 10 110394782 110395942 Rat 1305007 Ogfod3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 10 110409024 110436809 Rat 2302323 Hexdc hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 10 110436882 110455475 Rat 1562022 LOC619574 hypothetical protein LOC619574 10 110455406 110462225 Rat 1587449 LOC691137 hypothetical protein LOC691137 10 110468405 110470028 Rat 1310894 Narf nuclear prelamin A recognition factor 10 110476230 110494161 Rat 1305408 Foxk2 forkhead box K2 10 110499723 110551516 Rat 1305141 Wdr45b WD repeat domain 45B 10 110558417 110588534 Rat 1305663 Rab40b Rab40b, member RAS oncogene family 10 110590703 110618223 Rat 1304570 Fn3krp fructosamine-3-kinase-related protein 10 110647536 110655422 Rat 1559983 Fn3k fructosamine 3 kinase 10 110664291 110674692 Rat 2320148 Tbcd tubulin folding cofactor D 10 110676187 110717621 Rat 621562 Ubb ubiquitin B 10 139578694 139579068 Rat Markers in Region (RGSC Genome Assembly v3.4) The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Expected Size Chr Start Stop Species Match 5034970 BGH 65 10 95692424 95692700 Rat region 10642 D10Mit12 162 10 95695048 95695221 Rat region 10641 D10Wox22 157 10 95695076 95695218 Rat region 5073782 RH137635 151 10 95709592 95709742 Rat region 1641151 D10Wox43 148 10 95710270 95710417 Rat region 5070267 RH94568 152 10 95710736 95710887 Rat region 5507149 UniSTS:224857 71 10 95711184 95711254 Rat region 42933 D10Rat202 156 10 95739213 95739361 Rat region 5061376 BE099716 155 10 95741387 95741541 Rat region 5053537 RH142706 170 10 95768178 95768347 Rat region 5060578 BE110438 183 10 95769397 95769579 Rat region 5084560 AI177621 212 10 95772496 95772707 Rat region 5082181 BI280353 185 10 95790762 95790946 Rat region 5067162 AU047923 109 10 95881512 95881620 Rat region 5028218 D2Mit273 137 10 95885556 95885692 Rat region 5073586 RH137521 128 10 95945976 95946103 Rat region 5085870 AA866270 200 10 96001780 96001975 Rat region 5039412 RH127691 182 10 96056381 96056564 Rat region 5035719 WI-22548 224 10 96130742 96130965 Rat region 5034241 RH141897 197 10 96130894 96131090 Rat region 5500839 D17S1990 278 10 96131896 96132173 Rat region 5057474 AA858847 194 10 96132196 96132389 Rat region 5066218 PMC102575P1 570 10 96132411 96132980 Rat region 5035578 DDX5 164 10 96134117 96134280 Rat region 5028949 RH142936 235 10 96140624 96140858 Rat region 5053685 RH142792 127 10 96142463 96142589 Rat region 5078016 RH140093 184 10 96172197 96172380 Rat region 5074098 RH137820 159 10 96173981 96174139 Rat region 5030773 AW535161 182 10 96193326 96193507 Rat region 5074120 RH137833 130 10 96247446 96247575 Rat region 5029585 BE101386 165 10 96278191 96278355 Rat region 5042772 RH129636 229 10 96278955 96279183 Rat region 1579053 D10Chm232 275 10 96293906 96294180 Rat region 5057430 AI030123 215 10 96385730 96385944 Rat region 5054485 RH143251 196 10 96388696 96388890 Rat region 5044266 RH130504 199 10 96388814 96389012 Rat region 5040164 RH128126 203 10 96389635 96389837 Rat region 5061448 BE099833 164 10 96405872 96406035 Rat region 44824 D10Got142 117 10 96589983 96590100 Rat region 44824 D10Got142 117 10 96589984 96590100 Rat region 5045206 RH131045 200 10 96590674 96590873 Rat region 5087291 BQ208647 168 10 96593226 96593395 Rat 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Prkca 0 10 97368649 97368778 Rat region 7192918 Prkca 130 10 97368649 97368778 Rat region 5036452 Prkca 0 10 97368649 97368881 Rat region 7192916 Prkca 233 10 97368649 97368881 Rat region 1578980 D10Chm12 206 10 97454479 97454683 Rat region 5507029 fk85g05.x1 0 10 97469368 97470348 Rat region 1578978 D10Chm19 160 10 97470298 97470457 Rat region 34813 D10Rat16 166 10 97589540 97589703 Rat region 5073882 RH137693 207 10 97744352 97744558 Rat region 1578916 D10Chm234 278 10 97814841 97815118 Rat region 1628374 D0Got402 134 10 97938068 97938201 Rat region 5060746 BF389074 120 10 98041780 98041899 Rat region 1579146 D10Chm160 249 10 98119880 98120128 Rat region 40824 D10Rat138 223 10 98162829 98163052 Rat region 40824 D10Rat138 223 10 98162830 98163052 Rat region 44829 D10Got147 188 10 98164854 98165042 Rat region 44829 D10Got147 188 10 98164855 98165042 Rat region 5500863 AFM196xf6 1162 10 98169937 98171098 Rat region 5030365 AW533983 187 10 98220242 98220428 Rat region 1578923 D10Chm235 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105923824 Rat region 5079684 RH141143 189 10 105960261 105960449 Rat region 5040632 RH128394 190 10 106000263 106000452 Rat region 5053153 RH142484 121 10 106038171 106038291 Rat region 5500103 UniSTS:236779 255 10 106069758 106070012 Rat region 5073258 RH137332 212 10 106069849 106070060 Rat region 5053013 RH142404 166 10 106069965 106070130 Rat region 5026970 RH134228 200 10 106071902 106072101 Rat region 5067228 AU047884 145 10 106113958 106114102 Rat region 5044900 RH130868 198 10 106116343 106116540 Rat region 5051731 RH94625 162 10 106116448 106116609 Rat region 5507049 UniSTS:224180 158 10 106130722 106130879 Rat region 5048142 RH132732 180 10 106169274 106169453 Rat region 5050128 RH133878 207 10 106180994 106181200 Rat region 5049332 RH133420 203 10 106186158 106186360 Rat region 5072948 RH137146 197 10 106211432 106211628 Rat region 5055637 RH143916 105 10 106215535 106215639 Rat region 5046836 RH131982 0 10 106231384 106231594 Rat region 5039084 RH127503 184 10 106238788 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35711 D10Rat3 311 10 107084835 107085159 Rat region 5067216 AU047891 153 10 107135176 107135325 Rat region 1640921 D10Got220 133 10 107156612 107156744 Rat region 5034173 RH141646 215 10 107175168 107175382 Rat region 34202 D10Mgh16 134 10 107260495 107260629 Rat region 34202 D10Mgh16 134 10 107260496 107260629 Rat region 5067086 AU047973 167 10 107280014 107280180 Rat region 5071546 RH135145 183 10 107533547 107533729 Rat region 5067556 AU047674 158 10 107578693 107578850 Rat region 5047252 RH132221 196 10 107709183 107709378 Rat region 5031342 PMC148819P1 513 10 107958801 107959313 Rat region 5066304 PMC148819P2 137 10 107959177 107959313 Rat region 5504478 PMC22025P1 0 10 107959780 107960863 Rat region 5050968 RH134362 189 10 108014013 108014201 Rat region 5048838 RH133135 220 10 108114589 108114808 Rat region 36494 D10Rat5 172 10 108116569 108116741 Rat region 36494 D10Rat5 172 10 108116570 108116741 Rat region 5074772 RH138209 166 10 108266319 108266484 Rat region 5050154 RH133893 215 10 108309626 108309840 Rat region 5036462 Ppicap 218 10 108388298 108388515 Rat region 5036161 D11Bwg0554e 212 10 108405351 108405562 Rat region 5048688 RH133048 217 10 108405413 108405629 Rat region 5025628 RH129049 180 10 108452932 108453111 Rat region 41042 D10Rat134 207 10 108557381 108557588 Rat region 41042 D10Rat134 207 10 108557382 108557588 Rat region 5084746 AI228530 249 10 108608479 108608731 Rat region 5505526 D2S147 1153 10 108650504 108651656 Rat region 41584 D10Rat135 155 10 108776808 108776963 Rat region 41584 D10Rat135 155 10 108776809 108776963 Rat region 5054649 RH143345 100 10 108845525 108845624 Rat region 5040484 RH128310 208 10 108861717 108861924 Rat region 5077370 RH139717 217 10 108862647 108862863 Rat region 5506857 G46596 279 10 108866544 108866822 Rat region 5073440 RH137437 213 10 108887467 108887677 Rat region 5036438 Nptx1 114 10 108918408 108918521 Rat region 5054557 RH143293 141 10 108918839 108918979 Rat region 5040744 RH128458 212 10 108968472 108968689 Rat region 39292 D10Rat108 200 10 109048343 109048543 Rat region 39292 D10Rat108 200 10 109048344 109048543 Rat region 38514 D10Rat105 100 10 109310867 109310967 Rat region 38514 D10Rat105 100 10 109310868 109310967 Rat region 5088887 AU048829 154 10 109324701 109324854 Rat region 5047398 RH132304 185 10 109341390 109342563 Rat region 5028133 D11Mit298.5 127 10 109361138 109361264 Rat region 5502509 RH125153 90 10 109414764 109414853 Rat region 5039590 RH127793 187 10 109418900 109419086 Rat region 5078340 RH140284 219 10 109503141 109503359 Rat region 5075274 RH138500 121 10 109512579 109512699 Rat region 5075430 RH138589 152 10 109524827 109524978 Rat region 5028919 RH142821 216 10 109599361 109599576 Rat region 5045844 RH131411 205 10 109607417 109607621 Rat region 1634599 D10Got221 91 10 109620199 109620289 Rat region 5026196 RH131286 220 10 109657053 109657272 Rat region 5501986 MARC_21859-21860:1027094458:1 0 10 109734739 109735020 Rat region 5044850 RH130839 0 10 109737337 109737517 Rat region 5075200 RH138456 142 10 109793132 109793273 Rat region 5050870 RH134306 191 10 109795227 109795500 Rat region 1638942 D10Got222 123 10 109806026 109806148 Rat region 5500107 UniSTS:236796 281 10 109810008 109810288 Rat region 5080822 RH141802 202 10 109873865 109874066 Rat region 5072168 RH136692 120 10 109874899 109874973 Rat region 5072168 RH136692 120 10 109874899 109875018 Rat region 5025674 RH129223 191 10 109886692 109886882 Rat region 5053429 RH142644 167 10 109920896 109921062 Rat region 5053437 RH142648 164 10 109920924 109921087 Rat region 10627 D10Mcw1 166 10 109926227 109926395 Rat region 10627 D10Mcw1 166 10 109926228 109926395 Rat region 5503974 Gcgr 407 10 109928334 109929222 Rat region 5080030 RH141343 180 10 109929394 109929573 Rat region 1627618 D0Got916 154 10 109944702 109944855 Rat region 5073902 RH137705 230 10 109949478 109949707 Rat region 5042764 RH129632 202 10 109950266 109950467 Rat region 5050600 RH134150 215 10 109982347 109982561 Rat region 5040608 RH128381 191 10 109996724 109996914 Rat region 5053265 RH142548 108 10 110008001 110008108 Rat region 5045052 RH130955 212 10 110009727 110009938 Rat region 5499683 G73110 279 10 110011470 110012071 Rat region 5075606 RH138691 120 10 110015059 110015178 Rat region 5035000 Mafg 96 10 110021068 110021244 Rat region 5073278 RH137343 184 10 110030960 110031143 Rat region 5048146 RH132735 206 10 110038659 110038864 Rat region 5505788 UniSTS:493187 993 10 110039899 110040891 Rat region 5505642 UniSTS:487896 993 10 110039899 110040891 Rat region 1632748 D0Got821 231 10 110059759 110059989 Rat region 5503440 UniSTS:461931 536 10 110160805 110161340 Rat region 5052615 UniSTS:461932 567 10 110160805 110161371 Rat region 5033067 RH137468 188 10 110188485 110188672 Rat region 5028911 RH142791 203 10 110189862 110190064 Rat region 5083703 AI179937 229 10 110325927 110326155 Rat region 39576 D10Rat187 247 10 110385418 110385665 Rat region 39576 D10Rat187 247 10 110385419 110385665 Rat region 5080992 RH141901 215 10 110409141 110409355 Rat region 5051635 BB101812 126 10 110440627 110440752 Rat region 5050244 RH133944 214 10 110467748 110467954 Rat region 5043926 RH130310 204 10 110493783 110493986 Rat region 5042780 RH129641 219 10 110493920 110494138 Rat region 5501291 D18S1095 1413 10 110500261 110501673 Rat region 5033065 RH137462 203 10 110530115 110530317 Rat region 5046072 RH131542 202 10 110551251 110551452 Rat region 5087783 D16Bwg0193e 104 10 110558419 110558522 Rat region 5071434 RH135080 189 10 110673369 110674469 Rat region Position Markers Flank 1: (Gh1) Map Chr Position Strand Source Rat Cytogenetic Map 10 q32   NCBI RGSC Genome Assembly v5.0 10 94,237,414 - 94,239,391 - NCBI RGSC Genome Assembly v3.4 10 95,692,240 - 95,694,117 - NCBI Rat Celera Assembly 10 89,903,834 - 89,905,811 - NCBI Genome Assembly 3.1 10 95,708,476 - 95,710,261 - NCBI Flank 2: (D10Arb22) Map Chr Position Strand Source Rat Cytogenetic Map 10 q32.3   UniSTS RGSC Genome Assembly v5.0 10 107,484,612 - 107,484,761   UniSTS Rat Celera Assembly 10 102,615,292 - 102,615,441   UniSTS QTLs in Region (RGSC Genome Assembly v3.4) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 631530 Tls3 T-lymphoma susceptibility QTL 3 6.7 .0001 T-lymphoma susceptibility propylnitrosourea induced 10 53781298 100090301 Rat 631535 Cm51 Cardiac mass QTL 51 3 Cardiac mass 10 53792967 96584953 Rat 631542 Bp82 Blood pressure QTL 82 6.8 Blood pressure systolic 10 27184741 103551039 Rat 61436 Cia5 Collagen induced arthritis QTL 5 4.9 Joint/bone inflammation type II collagen induced 10 95692240 140692240 Rat 61449 Ciaa2 CIA Autoantibody QTL 2 7.1 Anti-type II collagen autoantibody titer collagen induced 10 64308668 95695218 Rat 1558652 Bw57 Body weight QTL 57 4.2 .0008 Body weight 10 95361338 140361338 Rat 1357344 Bp249 Blood pressure QTL 249 .0001 Blood pressure 10 69986912 102587587 Rat 631555 Bp134 Blood pressure QTL 134 .001 Blood pressure salt-loaded systolic 10 84262804 95694117 Rat 70171 Cari1 Carrageenan-induced inflammation QTL 1 4.9 .0005 Carrageenan-induced inflammation exudate volume 10 55851811 101848470 Rat 70193 Mcs7 Mammary carcinoma susceptibility QTL 7 2.38 Mammary tumor susceptibility 10 76698917 121698917 Rat 70364 Bp72 Blood pressure QTL 72 Blood pressure 10 55633982 100633982 Rat 61427 Cia16 Collagen induced arthritis QTL 16 3.2 Joint/bone inflammation type II collagen induced 10 6380753 100633982 Rat 61332 Eau3 Experimental allergic uveoretinitis QTL 3 .004 Uvea inflammation score 10 35713452 101848683 Rat 724530 Bp149 Blood pressure QTL 149 .0001 Blood pressure 10 95066219 99588446 Rat 61387 Bp1 Blood pressure QTL 1 5.1 Blood pressure 10 53800677 101848470 Rat 631558 Bp137 Blood pressure QTL 137 .013 Blood pressure 10 99198838 101355916 Rat 631567 Bp91 Blood pressure QTL 91 .0001 Blood pressure systolic 10 56848683 101848683 Rat 1358188 Ept9 Estrogen-induced pituitary tumorigenesis QTL 9 3.9 Gland mass pituitary 10 77092169 100633512 Rat 1298069 Bp168 Blood pressure QTL 168 5.5 Blood pressure salt-loaded systolic 10 27184741 102587587 Rat 1298078 Stresp5 Stress response QTL 5 2.99 .00025 Hormone level corticosterone 10 43458380 108776963 Rat 61354 Pia10 Pristane induced arthritis QTL 10 .01 Joint/bone inflammation pristane induced 10 24006429 160657542 Rat 70168 Eae12 Experimental allergic encephalomyelitis QTL 12 .0009 Brain/spinal cord inflammation demyelination 10 96667338 105886241 Rat 61396 Bp9 Blood pressure QTL 9 4.8 .0001 Blood pressure salt-loaded systolic 10 72871396 117871396 Rat 634320 Niddm49 Non-insulin dependent diabetes mellitus QTL 49 4.41 Glucose level postprandial 10 92782172 101848683 Rat 1300107 Rf18 Renal function QTL 18 3.4 Renal function salt-loaded urine volume 10 82474813 102865929 Rat 1300137 Bp186 Blood pressure QTL 186 3.57 Blood pressure salt-loaded time series calculation 10 95066219 140066219 Rat 631269 Cia22 Collagen induced arthritis QTL 22 8.9 Joint/bone inflammation type II collagen induced 10 41339689 152260081 Rat 631270 Cia23 Collagen induced arthritis QTL 23 3.9 Joint/bone inflammation type II collagen induced 10 41339689 152260081 Rat 631267 Cia20 Collagen induced arthritis QTL 20 3.2 Joint/bone inflammation type II collagen induced 10 24006429 160657542 Rat 631268 Cia21 Collagen induced arthritis QTL 21 3.1 Joint/bone inflammation type II collagen induced 10 14721135 159833317 Rat 1354641 Bvd2 Brain ventricular dilatation QTL 2 6.36 .001 Head/brain development brain ventricular dilatation 10 79981838 124981838 Rat 1302404 Cia27 Collagen induced arthritis QTL 27 Joint/bone inflammation type II collagen induced 10 95695048 111406914 Rat 1354608 Cm33 Cardiac mass QTL 33 2.8 Cardiac mass left ventricle 10 56930545 97589703 Rat 1358915 Stresp7 Stress response QTL 7 3.52 Hormone level norepinephrine 10 68955627 113955627 Rat 1554317 Bmd4 Bone mineral density QTL 4 9.4 .0001 Bone mineral density spine volumetric BMD by pQCT 10 20233281 104013574 Rat 1359017 Hrtrt21 Heart rate QTL 21 2.4 Heart rate stress-induced tachycardia 10 68526078 101292630 Rat 1549846 Scl47 Serum cholesterol level QTL 47 3.6 Lipid level baseline serum cholesterol 10 54091148 99091148 Rat 1576307 Cia28 Collagen induced arthritis QTL 28 Joint/bone inflammation type II collagen-induced 10 100633512 145633512 Rat 1576308 Schws1 Schwannoma susceptibility QTL 1 .0041 Neural tumor susceptibility tumor incidence, length of survival time 10 63816942 108816942 Rat 1576313 Pia25 Pristane induced arthritis QTL 25 Joint/bone inflammation pristane induced 10 100633512 145633512 Rat 1576319 Cia29 Collagen induced arthritis QTL 29 Joint/bone inflammation type II collagen-induced 10 35131252 95695218 Rat 6893336 Cm75 Cardiac mass QTL 75 .1 .87 Cardiac mass body weight adjusted 10 67677924 100865886 Rat 1558643 Cm44 Cardiac mass QTL 44 4.8 .0000368 Cardiac mass body weight adjusted 10 67677924 100865886 Rat 1578672 Bmd16 Bone mineral density QTL 16 6.2 Bone mineral density femoral neck cortical vBMD 10 101222719 146222719 Rat 1578663 Bss18 Bone structure and strength QTL 18 3.6 Bone structure femoral neck width 10 101222719 146222719 Rat 1579915 Bp280 Blood pressure QTL 280 .001 Blood pressure mean arterial pressure 10 94837236 99588446 Rat 2293646 Bss25 Bone structure and strength QTL 25 10.96 .0001 Bone structure 10 74167134 119167134 Rat 2293663 Bss33 Bone structure and strength QTL 33 9.34 .0001 Bone structure 10 74167134 119167134 Rat 2292436 Bp310 Blood pressure QTL 310 Blood pressure arterial 10 99233734 99588446 Rat 2292438 Bp311 Blood pressure QTL 311 Blood pressure arterial 10 79857808 99588446 Rat 2292617 Ept18 Estrogen-induced pituitary tumorigenesis QTL 18 3.9 Gland mass pituitary 10 77092169 100633512 Rat 1600367 Mcs15 Mammary carcinoma susceptibility QTL 15 4.5 Mammary tumor susceptibility 10 89575059 108822775 Rat 2303118 Mamtr7 Mammary tumor resistance QTL 7 .003 Mammary tumor resistance 10 9762188 108776963 Rat 2312668 Scl65 Serum cholesterol level QTL 65 .001 Lipid level serum cholesterol 10 106422174 107033716 Rat 2312672 Insul15 Insulin level QTL 15 .01 Insulin level serum 10 106422174 107033716 Rat 2298548 Neuinf7 Neuroinflammation QTL 7 2.2 Neuroinflammation 10 65668446 132729388 Rat 2312662 Slep8 Serum leptin concentration QTL 8 .05 Hormone level leptin 10 106422174 107033716 Rat 2303589 Bw87 Body weight QTL 87 2 Body weight 10 86057484 131057484 Rat 2301398 Kidm38 Kidney mass QTL 38 .002 Kidney mass 10 87834315 100429624 Rat 2300172 Bmd57 Bone mineral density QTL 57 9.8 .0001 Bone mineral density 10 74167134 119167134 Rat 2293698 Bss43 Bone structure and strength QTL 43 5.33 .0001 Bone structure 10 62984501 107984501 Rat 2300218 Hpcl2 Hepatic cholesterol level QTL 2 Lipid level cholesterol 10 46483646 100090301 Rat 2306792 Ean4 Experimental allergic neuritis QTL 4 4 Peripheral nerve inflammation demyelination 10 87849516 98392508 Rat 2306793 Ean5 Experimental allergic neuritis QTL 5 4.7 Peripheral nerve inflammation demyelination 10 76043832 98392296 Rat 2313856 Bp342 Blood pressure QTL 342 4.4 .0001 Blood pressure 10 91455572 100633982 Rat 2317039 Aia6 Adjuvant induced arthritis QTL 6 4.31 Joint/bone inflammation adjuvant induced 10 70229781 115229781 Rat 2317029 Aia19 Adjuvant induced arthritis QTL 19 2.98 Joint/bone inflammation adjuvant induced 10 70229781 115229781 Rat 2316949 Gluco60 Glucose level QTL 60 3.7 Glucose level postprandial 10 14721135 154166503 Rat 2317754 Glom25 Glomerulus QTL 25 3.5 Renal pathology urine protein level 10 86810917 131810917 Rat 4889492 Pancm2 Pancreatic morphology QTL 2 3.2 Pancreatic morphology 10 81350126 126350126 Rat 4889948 Bss91 Bone structure and strength QTL 91 4 Bone structure 10 86316831 96799937 Rat 631547 Bp87 Blood pressure QTL 87 4.5 Blood pressure 10 96799833 106897319 Rat 6893357 Bw102 Body weight QTL 102 .5 .36 Body weight 10 84262804 106479988 Rat 6893366 Bw106 Body weight QTL 106 .3 .47 Body weight 10 74652410 119652410 Rat 2306970 Anxrr22 Anxiety related response QTL 22 5.95 Anxiety response 10 67677924 102796362 Rat 1549831 Bss6 Bone structure and strength QTL 6 4 Bone strength Lumbar vertebra L5 ultimate force 10 61314296 106314296 Rat 1357340 Bp250 Blood pressure QTL 250 .0001 Blood pressure 10 101848470 146848470 Rat 61363 Oia3 Oil induced arthritis QTL 3 .001 Joint/bone inflammation oil induced 10 91455572 136455572 Rat 631526 Bp76 Blood pressure QTL 76 .0001 Blood pressure 10 69986912 102587587 Rat 631539 Oia6 Oil induced arthritis QTL 6 Joint/bone inflammation arthritis susceptibility 10 101532360 108776963 Rat 631538 Oia5 Oil induced arthritis QTL 5 Joint/bone inflammation arthritis susceptibility 10 91168332 136168332 Rat 61325 Aia5 Adjuvant induced arthritis QTL 5 .01 Joint/bone inflammation arthritis severity 10 24006429 160657542 Rat 70164 Bw21 Body weight QTL 21 4.36 .00005 Body weight 10 55851811 103550924 Rat Additional Information External Database Links Database Acc Id Source(s) Entrez Gene Cia5 Nomenclature History Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status 2006-04-14 Cia5  Collagen induced arthritis QTL 5    Type II Collagen induced arthritis QTL 5  Name updated 10779 APPROVED RGD Curation Notes Note Type Note Reference qtl_gene whole genome analysis using PGMapper revealed Map3k14, Ace, Stat3, Socs3, Tbx21 as RA associated genes and Ace as RA associated polymorphism either in coding or regulatory region 2300074 qtl_general DA.F344-(D10Arb20-D10Arb22) a congenic strain carrying this locus, develops less severe collagen-induced arthritis than the parental DA rats. 631168 qtl_general regulates the severity of collagen-induced arthritis 631168

More on Cia5 Genome Browser QTL Registration RGD Object Information RGD ID: 61436 Created: 2001-01-05 Species: Rattus norvegicus Last Modified: 2006-04-14 Status: ACTIVE