Gene: Nrk (Nik related kinase) Rattus norvegicus
Analyze
Symbol:
Nrk
Name:
Nik related kinase
RGD ID:
1566163
Description:
Predicted to enable protein kinase activity. Predicted to be involved in positive regulation of JNK cascade. Predicted to act upstream of or within negative regulation of cell population proliferation; parturition; and regulation of spongiotrophoblast cell proliferation. Orthologous to human NRK (Nik related kinase); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC315907; nik-related protein kinase; RGD1566163; similar to Nck-interacting kinase-like embryo specific kinase
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
NRK (Nik related kinase)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Nrk (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Nrk (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
NRK (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
NRK (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Nrk (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
NRK (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
NRK (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Nrk (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Nrk (Nik related kinase)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
NRK (Nik related kinase)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Nrk (Nik related kinase)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 107,159,154 - 107,256,417 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl X 107,159,233 - 107,256,417 (+) Ensembl GRCr8 mRatBN7.2 X 102,365,765 - 102,462,957 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 102,365,765 - 102,459,657 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx X 104,503,462 - 104,597,032 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 108,002,202 - 108,095,770 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 105,571,175 - 105,664,734 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 109,940,439 - 110,036,361 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 X 110,065,199 - 110,089,124 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 109,940,350 - 110,033,085 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 X 109,798,013 - 109,890,635 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 Rnor_5.0 X 109,913,500 - 109,944,079 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 X 126,448,334 - 126,541,575 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera X 103,155,670 - 103,249,235 (+) NCBI Celera Cytogenetic Map X q32 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Nrk Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Nrk (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Nrk Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Nrk (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Nrk Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Nrk (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Nrk Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Nrk (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of NRK mRNA CTD PMID:21570461 Nrk Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of NRK mRNA CTD PMID:32109520|PMID:33387578 Nrk Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of NRK mRNA CTD PMID:32109520 Nrk Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Nrk (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Nrk Rat 4,4'-sulfonyldiphenol multiple interactions ISO Nrk (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of NRK mRNA CTD PMID:30951980 Nrk Rat 4,4'-sulfonyldiphenol decreases methylation ISO NRK (Homo sapiens) 6480464 bisphenol S results in decreased methylation of NRK gene CTD PMID:31601247 Nrk Rat 4,4'-sulfonyldiphenol increases expression ISO Nrk (Mus musculus) 6480464 bisphenol S results in increased expression of NRK mRNA CTD PMID:30951980 Nrk Rat all-trans-retinoic acid increases expression ISO NRK (Homo sapiens) 6480464 Tretinoin results in increased expression of NRK mRNA CTD PMID:21934132 Nrk Rat all-trans-retinoic acid multiple interactions ISO Nrk (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of NRK mRNA CTD PMID:30951980 Nrk Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of NRK mRNA CTD PMID:35163327 Nrk Rat antirheumatic drug increases expression ISO NRK (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of NRK mRNA CTD PMID:24449571 Nrk Rat aristolochic acid A decreases expression ISO NRK (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of NRK mRNA CTD PMID:33212167 Nrk Rat arsane multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat arsenic atom multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat benzo[a]pyrene increases mutagenesis ISO NRK (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of NRK gene CTD PMID:25435355 Nrk Rat benzo[a]pyrene affects methylation ISO NRK (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of NRK 5' UTR; Benzo(a)pyrene affects the methylation of NRK promoter CTD PMID:27901495 Nrk Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of NRK mRNA CTD PMID:25181051 Nrk Rat bisphenol A multiple interactions ISO NRK (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of NRK gene CTD PMID:31601247 Nrk Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of NRK mRNA CTD PMID:34947998|PMID:41034487 Nrk Rat bisphenol A decreases expression ISO NRK (Homo sapiens) 6480464 bisphenol A results in decreased expression of NRK mRNA CTD PMID:29275510 Nrk Rat bisphenol A increases expression ISO Nrk (Mus musculus) 6480464 bisphenol A results in increased expression of NRK mRNA CTD PMID:30951980|PMID:34585602 Nrk Rat bisphenol A affects methylation ISO Nrk (Mus musculus) 6480464 bisphenol A affects the methylation of NRK promoter CTD PMID:27334623 Nrk Rat bisphenol A decreases methylation ISO Nrk (Mus musculus) 6480464 bisphenol A results in decreased methylation of NRK promoter CTD PMID:27312807 Nrk Rat bisphenol F increases expression ISO Nrk (Mus musculus) 6480464 bisphenol F results in increased expression of NRK mRNA CTD PMID:30951980 Nrk Rat cadmium dichloride increases expression ISO NRK (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of NRK mRNA CTD PMID:38568856 Nrk Rat chlordecone increases expression ISO Nrk (Mus musculus) 6480464 Chlordecone results in increased expression of NRK mRNA CTD PMID:33711761 Nrk Rat dextran sulfate decreases expression ISO Nrk (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of NRK mRNA CTD PMID:35093514 Nrk Rat dibutyl phthalate decreases expression ISO Nrk (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of NRK mRNA CTD PMID:21266533 Nrk Rat dioxygen increases expression ISO NRK (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of NRK mRNA CTD PMID:24236059 Nrk Rat dorsomorphin multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Nrk Rat doxorubicin decreases expression ISO Nrk (Mus musculus) 6480464 Doxorubicin results in decreased expression of NRK mRNA CTD PMID:39631538 Nrk Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of NRK mRNA CTD PMID:29391264 Nrk Rat entinostat increases expression ISO NRK (Homo sapiens) 6480464 entinostat results in increased expression of NRK mRNA CTD PMID:26272509 Nrk Rat entinostat multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Nrk Rat fulvestrant multiple interactions ISO NRK (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of NRK gene CTD PMID:31601247 Nrk Rat geldanamycin increases expression ISO NRK (Homo sapiens) 6480464 geldanamycin results in increased expression of NRK mRNA CTD PMID:26705709 Nrk Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of NRK mRNA CTD PMID:33387578 Nrk Rat isoflurane increases methylation ISO Nrk (Mus musculus) 6480464 Isoflurane results in increased methylation of NRK mRNA CTD PMID:35249202 Nrk Rat lead diacetate multiple interactions ISO Nrk (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which results in increased methylation of NRK more ... CTD PMID:33445541 Nrk Rat lead(0) multiple interactions ISO Nrk (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which results in increased methylation of NRK more ... CTD PMID:33445541 Nrk Rat manganese atom multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat manganese(0) multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat manganese(II) chloride multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat mercury dibromide multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Nrk Rat nickel atom decreases expression ISO NRK (Homo sapiens) 6480464 Nickel results in decreased expression of NRK mRNA CTD PMID:25583101 Nrk Rat panobinostat multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Nrk Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of NRK mRNA CTD PMID:33387578 Nrk Rat PCB138 multiple interactions ISO Nrk (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Nrk Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of NRK mRNA CTD PMID:35163327 Nrk Rat phenylmercury acetate increases expression ISO NRK (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of NRK mRNA CTD PMID:26272509 Nrk Rat phenylmercury acetate multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Nrk Rat potassium chromate increases expression ISO NRK (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of NRK mRNA CTD PMID:22714537 Nrk Rat potassium dichromate increases expression ISO NRK (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of NRK protein CTD PMID:23718831 Nrk Rat pyrogallol decreases expression ISO Nrk (Mus musculus) 6480464 Pyrogallol results in decreased expression of NRK mRNA CTD PMID:20362636 Nrk Rat SB 431542 multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Nrk Rat sevoflurane increases methylation ISO Nrk (Mus musculus) 6480464 Sevoflurane results in increased methylation of NRK mRNA CTD PMID:35249202 Nrk Rat sodium arsenite multiple interactions ISO NRK (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Nrk Rat sunitinib increases expression ISO NRK (Homo sapiens) 6480464 Sunitinib results in increased expression of NRK mRNA CTD PMID:31533062 Nrk Rat titanium dioxide increases methylation ISO Nrk (Mus musculus) 6480464 titanium dioxide results in increased methylation of NRK gene; titanium dioxide results in increased methylation more ... CTD PMID:35295148 Nrk Rat titanium dioxide increases expression ISO Nrk (Mus musculus) 6480464 titanium dioxide results in increased expression of NRK mRNA CTD PMID:35295148 Nrk Rat trichostatin A increases expression ISO NRK (Homo sapiens) 6480464 trichostatin A results in increased expression of NRK mRNA CTD PMID:24935251 Nrk Rat valproic acid increases methylation ISO NRK (Homo sapiens) 6480464 Valproic Acid results in increased methylation of NRK gene CTD PMID:29154799 Nrk Rat valproic acid increases expression ISO Nrk (Mus musculus) 6480464 Valproic Acid results in increased expression of NRK mRNA CTD PMID:24896083 Nrk Rat valproic acid increases expression ISO NRK (Homo sapiens) 6480464 Valproic Acid results in increased expression of NRK mRNA CTD PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509 Nrk Rat valproic acid multiple interactions ISO NRK (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386