Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dsn1 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of DSN1 mRNA | CTD | PMID:30723492 | Dsn1 | Rat | 17beta-estradiol | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DSN1 mRNA | CTD | PMID:24758408 | Dsn1 | Rat | 17beta-estradiol | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of DSN1 mRNA | CTD | PMID:31614463 | Dsn1 | Rat | 17beta-estradiol | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | EGF protein inhibits the reaction [Estradiol results in increased expression of DSN1 mRNA] | CTD | PMID:24758408 | Dsn1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of DSN1 mRNA | CTD | PMID:31388691 | Dsn1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DSN1 mRNA | CTD | PMID:20106945|PMID:21632981 | Dsn1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DSN1 mRNA | CTD | PMID:33387578 | Dsn1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | DSN1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DSN1 mRNA | CTD | PMID:22574217 | Dsn1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dsn1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DSN1 mRNA | CTD | PMID:21570461 | Dsn1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of DSN1 mRNA | CTD | PMID:24780913 | Dsn1 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of DSN1 mRNA | CTD | PMID:31881176 | Dsn1 | Rat | acrolein | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of DSN1 more ... | CTD | PMID:32699268 | Dsn1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of DSN1 mRNA | CTD | PMID:28959563 | Dsn1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of DSN1 mRNA | CTD | PMID:23630614|PMID:25378103 | Dsn1 | Rat | aflatoxin B1 | decreases methylation | ISO | DSN1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DSN1 gene | CTD | PMID:27153756 | Dsn1 | Rat | all-trans-retinoic acid | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DSN1 mRNA | CTD | PMID:33167477 | Dsn1 | Rat | alpha-pinene | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of DSN1 more ... | CTD | PMID:32699268 | Dsn1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of DSN1 mRNA | CTD | PMID:30779732 | Dsn1 | Rat | arsane | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | arsenic atom | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | arsenite(3-) | decreases expression | ISO | Dsn1 (Mus musculus) | 6480464 | arsenite results in decreased expression of DSN1 mRNA | CTD | PMID:18929588 | Dsn1 | Rat | azathioprine | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of DSN1 mRNA | CTD | PMID:22623647 | Dsn1 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | DSN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of DSN1 gene | CTD | PMID:25435355 | Dsn1 | Rat | benzo[a]pyrene | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of DSN1 mRNA | CTD | PMID:32234424 | Dsn1 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of DSN1 mRNA | CTD | PMID:26238291 | Dsn1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DSN1 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Dsn1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DSN1 mRNA | CTD | PMID:32145629 | Dsn1 | Rat | bisphenol A | affects expression | ISO | DSN1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of DSN1 mRNA | CTD | PMID:30903817 | Dsn1 | Rat | bisphenol A | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of DSN1 mRNA | CTD | PMID:29275510 | Dsn1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in decreased methylation of DSN1 gene | CTD | PMID:28505145 | Dsn1 | Rat | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of DSN1 gene | CTD | PMID:28505145 | Dsn1 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of DSN1 mRNA | CTD | PMID:19167457 | Dsn1 | Rat | carbon nanotube | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of DSN1 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Dsn1 | Rat | chlorpyrifos | decreases expression | ISO | Dsn1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DSN1 mRNA | CTD | PMID:37019170 | Dsn1 | Rat | chromium(6+) | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... | CTD | PMID:38479592 | Dsn1 | Rat | cisplatin | increases phosphorylation | ISO | Dsn1 (Mus musculus) | 6480464 | Cisplatin results in increased phosphorylation of DSN1 protein | CTD | PMID:22006019 | Dsn1 | Rat | cisplatin | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of DSN1 mRNA | CTD | PMID:27392435 | Dsn1 | Rat | cisplatin | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of DSN1 mRNA | CTD | PMID:27594783 | Dsn1 | Rat | copper(II) sulfate | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DSN1 mRNA | CTD | PMID:19549813 | Dsn1 | Rat | coumarin | decreases phosphorylation | ISO | DSN1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of DSN1 protein | CTD | PMID:35688186 | Dsn1 | Rat | coumestrol | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DSN1 mRNA; [Coumestrol co-treated with resveratrol] more ... | CTD | PMID:19167446 | Dsn1 | Rat | coumestrol | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of DSN1 mRNA | CTD | PMID:19167446 | Dsn1 | Rat | cyclosporin A | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of DSN1 mRNA | CTD | PMID:19770486 | Dsn1 | Rat | cyclosporin A | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of DSN1 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:25562108 | Dsn1 | Rat | diazinon | increases methylation | ISO | DSN1 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of DSN1 gene | CTD | PMID:22964155 | Dsn1 | Rat | dicrotophos | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DSN1 mRNA | CTD | PMID:28302478 | Dsn1 | Rat | dioxygen | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of DSN1 mRNA | CTD | PMID:26516004 | Dsn1 | Rat | Enterolactone | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DSN1 mRNA | CTD | PMID:19167446 | Dsn1 | Rat | enzyme inhibitor | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Dsn1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DSN1 mRNA | CTD | PMID:24793618 | Dsn1 | Rat | FR900359 | affects phosphorylation | ISO | DSN1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of DSN1 protein | CTD | PMID:37730182 | Dsn1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of DSN1 mRNA | CTD | PMID:25539665 | Dsn1 | Rat | genistein | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in decreased methylation of DSN1 gene | CTD | PMID:28505145 | Dsn1 | Rat | leflunomide | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of DSN1 mRNA | CTD | PMID:28988120 | Dsn1 | Rat | manganese atom | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | manganese(0) | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | manganese(II) chloride | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | methyl methanesulfonate | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DSN1 mRNA | CTD | PMID:23649840 | Dsn1 | Rat | okadaic acid | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of DSN1 mRNA | CTD | PMID:38832940 | Dsn1 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of DSN1 mRNA | CTD | PMID:25729387 | Dsn1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DSN1 mRNA | CTD | PMID:25729387 | Dsn1 | Rat | ozone | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of DSN1 more ... | CTD | PMID:32699268 | Dsn1 | Rat | ozone | multiple interactions | ISO | Dsn1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Dsn1 | Rat | paracetamol | increases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DSN1 mRNA | CTD | PMID:22230336 | Dsn1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DSN1 mRNA | CTD | PMID:33387578 | Dsn1 | Rat | pirinixic acid | multiple interactions | ISO | Dsn1 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of DSN1 mRNA | CTD | PMID:20813756 | Dsn1 | Rat | pirinixic acid | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DSN1 mRNA | CTD | PMID:20813756|PMID:23811191 | Dsn1 | Rat | propanal | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of DSN1 mRNA | CTD | PMID:26079696 | Dsn1 | Rat | resveratrol | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in increased expression of DSN1 mRNA; [Plant Extracts co-treated with more ... | CTD | PMID:19167446|PMID:23557933 | Dsn1 | Rat | sodium arsenite | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DSN1 mRNA | CTD | PMID:38568856 | Dsn1 | Rat | sodium arsenite | multiple interactions | ISO | DSN1 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Dsn1 | Rat | sunitinib | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of DSN1 mRNA | CTD | PMID:31533062 | Dsn1 | Rat | temozolomide | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of DSN1 mRNA | CTD | PMID:31758290 | Dsn1 | Rat | testosterone enanthate | affects expression | ISO | DSN1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of DSN1 mRNA | CTD | PMID:17440010 | Dsn1 | Rat | tetrachloromethane | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DSN1 mRNA | CTD | PMID:31919559 | Dsn1 | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of DSN1 mRNA | CTD | PMID:34492290 | Dsn1 | Rat | thiram | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of DSN1 mRNA | CTD | PMID:38568856 | Dsn1 | Rat | titanium dioxide | decreases methylation | ISO | Dsn1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DSN1 gene | CTD | PMID:35295148 | Dsn1 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of DSN1 mRNA | CTD | PMID:25729387 | Dsn1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DSN1 mRNA | CTD | PMID:25729387 | Dsn1 | Rat | trichloroethene | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of DSN1 mRNA | CTD | PMID:25549359 | Dsn1 | Rat | trimellitic anhydride | increases expression | ISO | Dsn1 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of DSN1 mRNA | CTD | PMID:19042947 | Dsn1 | Rat | trovafloxacin | decreases expression | ISO | Dsn1 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of DSN1 mRNA | CTD | PMID:35537566 | Dsn1 | Rat | urethane | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of DSN1 mRNA | CTD | PMID:28818685 | Dsn1 | Rat | valproic acid | affects expression | ISO | DSN1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DSN1 mRNA | CTD | PMID:25979313 | Dsn1 | Rat | valproic acid | decreases expression | ISO | DSN1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DSN1 mRNA | CTD | PMID:28001369 | Dsn1 | Rat | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of DSN1 mRNA | CTD | PMID:29427782 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















