Dsn1 (DSN1 component of MIS12 kinetochore complex) - Rat Genome Database

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Gene: Dsn1 (DSN1 component of MIS12 kinetochore complex) Heterocephalus glaber
Analyze
Symbol: Dsn1
Name: DSN1 component of MIS12 kinetochore complex
RGD ID: 18922092
Description: INVOLVED IN skeletal muscle satellite cell proliferation (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); focal epilepsy (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (inferred); fibrillar center (inferred); kinetochore (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DSN1 homolog, MIS12 kinetochore complex component; DSN1, MIND kinetochore complex component, homolog; kinetochore-associated protein DSN1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248422,738,734 - 2,760,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248422,738,739 - 2,762,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dsn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248422,738,734 - 2,760,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248422,738,739 - 2,762,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DSN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382036,751,795 - 36,773,763 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2036,751,791 - 36,773,818 (-)EnsemblGRCh38hg38GRCh38
GRCh372035,380,198 - 35,402,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362034,813,862 - 34,835,563 (-)NCBINCBI36Build 36hg18NCBI36
Build 342034,813,861 - 34,835,563NCBI
Celera2032,087,712 - 32,109,752 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,116,840 - 32,138,884 (-)NCBIHuRef
CHM1_12035,281,951 - 35,303,991 (-)NCBICHM1_1
T2T-CHM13v2.02038,476,075 - 38,498,047 (-)NCBIT2T-CHM13v2.0
Dsn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392156,836,982 - 156,848,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2156,837,185 - 156,849,074 (-)EnsemblGRCm39 Ensembl
GRCm382156,995,062 - 157,007,075 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2156,995,265 - 157,007,154 (-)EnsemblGRCm38mm10GRCm38
MGSCv372156,820,798 - 156,832,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362156,686,706 - 156,698,516 (-)NCBIMGSCv36mm8
Celera2162,930,851 - 162,942,859 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.89NCBI
Dsn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,072,775 - 166,089,029 (-)NCBIGRCr8
mRatBN7.23145,652,741 - 145,668,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,652,737 - 145,665,856 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3149,479,403 - 149,491,260 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03157,977,892 - 157,989,744 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03155,717,666 - 155,729,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03153,101,020 - 153,115,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3153,101,036 - 153,114,520 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,598,732 - 158,611,011 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43147,575,110 - 147,586,968 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3144,362,164 - 144,374,022 (-)NCBICelera
Cytogenetic Map3q42NCBI
Dsn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBIChiLan1.0ChiLan1.0
DSN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,488,112 - 42,510,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,481,210 - 42,503,230 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,083,222 - 33,105,563 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,202,053 - 34,223,735 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,202,053 - 34,223,729 (-)Ensemblpanpan1.1panPan2
DSN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12425,506,954 - 25,523,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2425,507,667 - 25,523,155 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,152,621 - 25,168,599 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,204,555 - 26,220,531 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,204,405 - 26,220,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12425,482,726 - 25,498,705 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02425,582,494 - 25,598,740 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,072,339 - 26,088,326 (-)NCBIUU_Cfam_GSD_1.0
Dsn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640174,411,961 - 174,426,798 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365614,322,675 - 4,337,506 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365614,322,709 - 4,337,405 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1739,990,624 - 40,017,365 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11739,992,769 - 40,017,388 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,435,426 - 45,457,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1257,511,171 - 57,525,241 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl257,511,366 - 57,527,088 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666054533,022 - 551,858 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004867819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004867820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004867821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004867822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004867823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01087782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01004732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000014771   ⟹   ENSHGLP00000014626
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248422,738,734 - 2,760,783 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000014772   ⟹   ENSHGLP00000014627
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248422,740,359 - 2,757,933 (+)Ensembl
RefSeq Acc Id: XM_004867819   ⟹   XP_004867876
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_004867820   ⟹   XP_004867877
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_004867821   ⟹   XP_004867878
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,750 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_004867822   ⟹   XP_004867879
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,750 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_004867823   ⟹   XP_004867880
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,749 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_013066711   ⟹   XP_012922165
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246960   ⟹   XP_021102619
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246961   ⟹   XP_021102620
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246962   ⟹   XP_021102621
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,747 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246963   ⟹   XP_021102622
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,750 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246964   ⟹   XP_021102623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,749 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246965   ⟹   XP_021102624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,739 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246966   ⟹   XP_021102625
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,748 - 2,762,968 (+)NCBI
RefSeq Acc Id: XM_021246967   ⟹   XP_021102626
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248422,738,749 - 2,762,968 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021102624   ⟸   XM_021246965
- Peptide Label: isoform X10
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867876   ⟸   XM_004867819
- Peptide Label: isoform X1
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922165   ⟸   XM_013066711
- Peptide Label: isoform X2
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102619   ⟸   XM_021246960
- Peptide Label: isoform X3
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102620   ⟸   XM_021246961
- Peptide Label: isoform X4
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867877   ⟸   XM_004867820
- Peptide Label: isoform X6
- UniProtKB: A0A0P6J3V6 (UniProtKB/TrEMBL),   G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102621   ⟸   XM_021246962
- Peptide Label: isoform X7
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102625   ⟸   XM_021246966
- Peptide Label: isoform X13
RefSeq Acc Id: XP_004867880   ⟸   XM_004867823
- Peptide Label: isoform X12
RefSeq Acc Id: XP_021102623   ⟸   XM_021246964
- Peptide Label: isoform X9
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102626   ⟸   XM_021246967
- Peptide Label: isoform X14
RefSeq Acc Id: XP_004867878   ⟸   XM_004867821
- Peptide Label: isoform X5
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102622   ⟸   XM_021246963
- Peptide Label: isoform X8
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867879   ⟸   XM_004867822
- Peptide Label: isoform X11
- UniProtKB: G5B831 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014626   ⟸   ENSHGLT00000014771
RefSeq Acc Id: ENSHGLP00000014627   ⟸   ENSHGLT00000014772


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010464 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014771 ENTREZGENE
InterPro Dsn1/Mis13 UniProtKB/TrEMBL
NCBI Gene Dsn1 ENTREZGENE
PANTHER KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG UniProtKB/TrEMBL
  PTHR14778 UniProtKB/TrEMBL
Pfam MIS13 UniProtKB/TrEMBL
UniProt A0A0P6J3V6 ENTREZGENE, UniProtKB/TrEMBL
  G5B831 ENTREZGENE, UniProtKB/TrEMBL