Slc15a5 (solute carrier family 15, member 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Slc15a5 (solute carrier family 15, member 5) Rattus norvegicus
Analyze
Symbol: Slc15a5
Name: solute carrier family 15, member 5
RGD ID: 1564925
Description: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Orthologous to human SLC15A5 (solute carrier family 15 member 5); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC502918; RGD1564925; similar to hypothetical protein 9830102E05; solute carrier family 15 member 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84172,609,293 - 172,702,893 (-)NCBIGRCr8
mRatBN7.24170,878,021 - 170,971,620 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4170,878,021 - 170,971,620 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4177,173,067 - 177,266,669 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04172,957,259 - 173,050,845 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04171,577,779 - 171,671,367 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04171,970,620 - 172,063,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4171,970,620 - 172,063,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04236,224,617 - 236,317,092 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44175,098,364 - 175,191,369 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4159,452,735 - 159,545,830 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Slc15a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84172,609,293 - 172,702,893 (-)NCBIGRCr8
mRatBN7.24170,878,021 - 170,971,620 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4170,878,021 - 170,971,620 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4177,173,067 - 177,266,669 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04172,957,259 - 173,050,845 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04171,577,779 - 171,671,367 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04171,970,620 - 172,063,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4171,970,620 - 172,063,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04236,224,617 - 236,317,092 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44175,098,364 - 175,191,369 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4159,452,735 - 159,545,830 (-)NCBICelera
Cytogenetic Map4q44NCBI
SLC15A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381216,188,485 - 16,277,685 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1216,188,485 - 16,277,685 (-)EnsemblGRCh38hg38GRCh38
GRCh371216,341,419 - 16,430,619 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361216,233,869 - 16,321,886 (-)NCBINCBI36Build 36hg18NCBI36
Celera1221,486,383 - 21,574,381 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1216,110,761 - 16,198,741 (-)NCBIHuRef
CHM1_11216,307,411 - 16,395,372 (-)NCBICHM1_1
T2T-CHM13v2.01216,065,864 - 16,155,028 (-)NCBIT2T-CHM13v2.0
Slc15a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396137,960,584 - 138,056,914 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6137,960,584 - 138,056,914 (-)EnsemblGRCm39 Ensembl
GRCm386137,983,586 - 138,079,916 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6137,983,586 - 138,079,916 (-)EnsemblGRCm38mm10GRCm38
MGSCv376137,932,111 - 138,028,437 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366137,947,786 - 138,037,394 (-)NCBIMGSCv36mm8
Celera6141,048,720 - 141,143,799 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map667.96NCBI
Slc15a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541312,832,193 - 12,924,836 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541312,832,193 - 12,924,836 (-)NCBIChiLan1.0ChiLan1.0
SLC15A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21021,635,901 - 21,723,724 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11221,632,662 - 21,720,485 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01216,190,038 - 16,277,911 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11216,586,139 - 16,674,013 (-)NCBIpanpan1.1PanPan1.1panPan2
SLC15A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12730,452,346 - 30,534,393 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2730,414,299 - 30,534,100 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2715,913,616 - 15,995,287 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02730,772,519 - 30,854,218 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2730,772,513 - 30,853,930 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12730,719,403 - 30,744,564 (+)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.12730,623,335 - 30,690,490 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02730,619,522 - 30,701,397 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02715,633,835 - 15,715,524 (-)NCBIUU_Cfam_GSD_1.0
Slc15a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494591,621,762 - 91,704,767 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365871,349,397 - 1,432,155 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365871,349,397 - 1,432,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC15A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl556,345,871 - 56,429,368 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1556,345,871 - 56,430,645 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2559,635,863 - 59,718,270 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC15A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,103,843 - 16,198,937 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,106,887 - 16,197,599 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606919,095,894 - 19,193,747 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc15a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475221,798,306 - 21,887,888 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475221,798,306 - 21,887,928 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc15a5
639 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:80
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000010158
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat

Markers in Region
D4Rat242  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24170,963,353 - 170,963,565 (+)MAPPERmRatBN7.2
Rnor_6.04172,055,125 - 172,055,336NCBIRnor6.0
Rnor_5.04236,308,826 - 236,309,037UniSTSRnor5.0
RGSC_v3.44175,183,103 - 175,183,314UniSTSRGSC3.4
RGSC_v3.44175,183,102 - 175,183,313RGDRGSC3.4
RGSC_v3.14175,428,226 - 175,428,437RGD
Celera4159,537,565 - 159,537,775UniSTS
RH 3.4 Map41029.9UniSTS
RH 3.4 Map41029.9RGD
RH 2.0 Map41087.3RGD
SHRSP x BN Map491.8799RGD
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 55 45 47 34 8 34 4 55 10 50 9 38 13

Sequence


Ensembl Acc Id: ENSRNOT00000010158   ⟹   ENSRNOP00000010157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4170,878,021 - 170,971,620 (-)Ensembl
Rnor_6.0 Ensembl4171,970,620 - 172,063,391 (-)Ensembl
RefSeq Acc Id: NM_001192015   ⟹   NP_001178944
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84172,609,293 - 172,702,893 (-)NCBI
mRatBN7.24170,878,021 - 170,971,620 (-)NCBI
Rnor_6.04171,970,620 - 172,063,391 (-)NCBI
Rnor_5.04236,224,617 - 236,317,092 (-)NCBI
Celera4159,452,735 - 159,545,830 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178944 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM01576 (Get FASTA)   NCBI Sequence Viewer  
  EDM01577 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010157.5
RefSeq Acc Id: NP_001178944   ⟸   NM_001192015
- UniProtKB: D3ZKX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010157   ⟸   ENSRNOT00000010158

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKX5-F1-model_v2 AlphaFold D3ZKX5 1-571 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564925 AgrOrtholog
BioCyc Gene G2FUF-42564 BioCyc
Ensembl Genes ENSRNOG00000007717 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010158.6 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_trans_sf UniProtKB/TrEMBL
  Oligopeptide_transporter UniProtKB/TrEMBL
KEGG Report rno:502918 UniProtKB/TrEMBL
NCBI Gene 502918 ENTREZGENE
PANTHER PTHR11654 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 15 MEMBER 5 UniProtKB/TrEMBL
Pfam PTR2 UniProtKB/TrEMBL
PhenoGen Slc15a5 PhenoGen
RatGTEx ENSRNOG00000007717 RatGTEx
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt D3ZKX5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-06-12 Slc15a5  solute carrier family 15, member 5  RGD1564925  similar to hypothetical protein 9830102E05   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564925  similar to hypothetical protein 9830102E05   RGD1564925_predicted  similar to hypothetical protein 9830102E05 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564925_predicted  similar to hypothetical protein 9830102E05 (predicted)  LOC502918  similar to hypothetical protein 9830102E05  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502918  similar to hypothetical protein 9830102E05      Symbol and Name status set to provisional 70820 PROVISIONAL