Acap2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Acap2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2) Rattus norvegicus
Analyze
Symbol: Acap2
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
RGD ID: 1562939
Description: Predicted to enable GTPase activator activity; phosphatidylinositol-3,5-bisphosphate binding activity; and small GTPase binding activity. Involved in cellular response to nerve growth factor stimulus and endocytic recycling. Located in endosome membrane. Orthologous to human ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; centaurin, beta 2; centaurin-beta-2; Centb2; cnt-b2; similar to Centaurin beta 2 (Cnt-b2)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,043,442 - 83,159,105 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1183,043,511 - 83,159,107 (+)EnsemblGRCr8
mRatBN7.21169,538,487 - 69,654,156 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,538,546 - 69,654,151 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1178,375,542 - 78,488,194 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,030,356 - 71,146,074 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01170,064,630 - 70,177,282 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01173,078,966 - 73,193,496 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)Ensemblrn6Rnor6.0
Rnor_5.01176,151,871 - 76,266,156 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41171,411,706 - 71,524,828 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1168,958,302 - 69,050,569 (+)NCBICelera
Celera11602,159 - 617,137 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
endosome membrane  (IBA,IDA,IEA)
plasma membrane  (IEA,ISO,ISS)
ruffle  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth. Kobayashi H and Fukuda M, J Cell Sci. 2013 Jun 1;126(Pt 11):2424-35. doi: 10.1242/jcs.117846. Epub 2013 Apr 9.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11001876   PMID:11062263   PMID:19946888   PMID:22344257   PMID:24600047   PMID:25694427  


Genomics

Comparative Map Data
Acap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,043,442 - 83,159,105 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1183,043,511 - 83,159,107 (+)EnsemblGRCr8
mRatBN7.21169,538,487 - 69,654,156 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1169,538,546 - 69,654,151 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1178,375,542 - 78,488,194 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,030,356 - 71,146,074 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01170,064,630 - 70,177,282 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01173,078,966 - 73,193,496 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)Ensemblrn6Rnor6.0
Rnor_5.01176,151,871 - 76,266,156 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41171,411,706 - 71,524,828 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1168,958,302 - 69,050,569 (+)NCBICelera
Celera11602,159 - 617,137 (-)NCBICelera
Cytogenetic Map11q22NCBI
ACAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383195,274,745 - 195,443,020 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3195,274,738 - 195,443,091 (-)Ensemblhg38GRCh38
GRCh373194,995,474 - 195,163,749 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363196,476,768 - 196,645,041 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343196,476,775 - 196,645,049NCBI
Celera3193,403,894 - 193,572,181 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3192,371,085 - 192,539,531 (-)NCBIHuRef
CHM1_13194,958,324 - 195,126,679 (-)NCBICHM1_1
T2T-CHM13v2.03197,972,626 - 198,140,907 (-)NCBIT2T-CHM13v2.0
Acap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391630,911,230 - 31,020,105 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1630,911,230 - 31,020,063 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381631,092,412 - 31,201,285 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1631,092,412 - 31,201,245 (-)Ensemblmm10GRCm38
MGSCv371631,092,499 - 31,201,324 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361631,012,160 - 31,120,985 (-)NCBIMGSCv36mm8
Celera1631,599,552 - 31,709,042 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1621.34NCBI
Acap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542013,650,215 - 13,773,022 (+)Ensembl
ChiLan1.0NW_00495542013,649,482 - 13,777,353 (+)NCBIChiLan1.0ChiLan1.0
ACAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22193,204,439 - 193,377,373 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13193,209,165 - 193,382,092 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03192,577,813 - 192,750,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13202,876,826 - 203,048,239 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3202,876,819 - 203,048,239 (-)EnsemblpanPan2panpan1.1
ACAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13330,588,450 - 30,717,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3330,587,756 - 30,716,229 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3330,616,392 - 30,748,126 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03330,842,887 - 30,971,404 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3330,842,829 - 30,973,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13330,637,602 - 30,769,036 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03330,673,447 - 30,804,928 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03331,296,464 - 31,424,933 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602143,758,740 - 143,864,040 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493683373,752 - 179,057 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13132,274,227 - 132,431,385 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113132,274,229 - 132,431,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213141,934,497 - 141,974,905 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11589,341,026 - 89,516,816 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1589,340,947 - 89,516,815 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604163,073,360 - 63,280,046 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473062,643,017 - 62,766,389 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473062,642,897 - 62,770,816 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Acap2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1416,006,345 - 16,114,235 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Acap2
324 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:278
Count of miRNA genes:185
Interacting mature miRNAs:212
Transcripts:ENSRNOT00000029549
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
RH132336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,648,646 - 69,648,862 (+)MAPPERmRatBN7.2
Rnor_6.01173,188,589 - 73,188,804NCBIRnor6.0
Rnor_5.01176,260,010 - 76,260,225UniSTSRnor5.0
RGSC_v3.41171,522,284 - 71,522,499UniSTSRGSC3.4
Celera11605,354 - 605,569UniSTS
RH 3.4 Map11554.33UniSTS
Cytogenetic Map11q22UniSTS
BI296803  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,538,146 - 69,538,319 (+)MAPPERmRatBN7.2
Rnor_6.01173,078,583 - 73,078,755NCBIRnor6.0
Rnor_5.01176,151,476 - 76,151,648UniSTSRnor5.0
RGSC_v3.41171,411,307 - 71,411,479UniSTSRGSC3.4
Celera1168,957,905 - 68,958,077UniSTS
RH 3.4 Map11404.7UniSTS
Cytogenetic Map11q22UniSTS
AU047727  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21169,540,490 - 69,540,658 (+)MAPPERmRatBN7.2
Rnor_6.01173,080,925 - 73,081,092NCBIRnor6.0
Rnor_5.01176,153,819 - 76,153,986UniSTSRnor5.0
RGSC_v3.41171,413,649 - 71,413,816UniSTSRGSC3.4
Celera1168,960,245 - 68,960,412UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 13 84 213 91 90 59 144 59 6 462 267 18 195 112 118 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000029549   ⟹   ENSRNOP00000030250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1183,043,547 - 83,159,107 (+)Ensembl
mRatBN7.2 Ensembl1169,538,546 - 69,651,191 (+)Ensembl
Rnor_6.0 Ensembl1173,078,982 - 73,191,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080834   ⟹   ENSRNOP00000073162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1183,043,511 - 83,159,104 (+)Ensembl
mRatBN7.2 Ensembl1169,586,554 - 69,654,151 (+)Ensembl
Rnor_6.0 Ensembl1173,079,168 - 73,190,350 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094946   ⟹   ENSRNOP00000082482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1183,043,511 - 83,159,104 (+)Ensembl
mRatBN7.2 Ensembl1169,538,546 - 69,651,191 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000140266   ⟹   ENSRNOP00000104146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1183,043,547 - 83,159,107 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165029   ⟹   ENSRNOP00000108925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1183,043,547 - 83,159,107 (+)Ensembl
RefSeq Acc Id: NM_001034006   ⟹   NP_001029178
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81183,043,503 - 83,156,143 (+)NCBI
mRatBN7.21169,538,546 - 69,651,191 (+)NCBI
Rnor_6.01173,078,982 - 73,191,133 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
RGSC_v3.41171,411,706 - 71,524,828 (+)RGD
Celera1168,958,302 - 69,050,569 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248487   ⟹   XP_006248549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81183,043,444 - 83,159,105 (+)NCBI
mRatBN7.21169,538,489 - 69,654,156 (+)NCBI
Rnor_6.01173,078,968 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248489   ⟹   XP_006248551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81183,043,442 - 83,159,105 (+)NCBI
mRatBN7.21169,538,490 - 69,654,156 (+)NCBI
Rnor_6.01173,078,968 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248491   ⟹   XP_006248553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81183,043,444 - 83,159,105 (+)NCBI
mRatBN7.21169,538,492 - 69,654,156 (+)NCBI
Rnor_6.01173,078,969 - 73,193,496 (+)NCBI
Rnor_5.01176,151,871 - 76,266,156 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001029178 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248549 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248551 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248553 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH90073 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073162
  ENSRNOP00000082482
GenBank Protein Q5FVC7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001029178   ⟸   NM_001034006
- UniProtKB: Q5FVC7 (UniProtKB/Swiss-Prot),   A0A8L2QG26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248549   ⟸   XM_006248487
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QG26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248551   ⟸   XM_006248489
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QG26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248553   ⟸   XM_006248491
- Peptide Label: isoform X3
- UniProtKB: A0A8L2QG26 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073162   ⟸   ENSRNOT00000080834
Ensembl Acc Id: ENSRNOP00000030250   ⟸   ENSRNOT00000029549
Ensembl Acc Id: ENSRNOP00000082482   ⟸   ENSRNOT00000094946
Ensembl Acc Id: ENSRNOP00000104146   ⟸   ENSRNOT00000140266
Ensembl Acc Id: ENSRNOP00000108925   ⟸   ENSRNOT00000165029
Protein Domains
Arf-GAP   BAR   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVC7-F1-model_v2 AlphaFold Q5FVC7 1-770 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698224
Promoter ID:EPDNEW_R8748
Type:initiation region
Name:Acap2_1
Description:ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01173,079,095 - 73,079,155EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562939 AgrOrtholog
BioCyc Gene G2FUF-21050 BioCyc
Ensembl Genes ENSRNOG00000001730 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000080834 ENTREZGENE
  ENSRNOT00000094946 ENTREZGENE
Gene3D-CATH 1.10.220.150 UniProtKB/Swiss-Prot
  1.20.1270.60 UniProtKB/Swiss-Prot
  1.25.40.20 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7114273 IMAGE-MGC_LOAD
InterPro ACAP1/2/3-like UniProtKB/Swiss-Prot
  AH/BAR_dom_sf UniProtKB/Swiss-Prot
  Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  ARFGAP/RecO UniProtKB/Swiss-Prot
  ArfGAP_dom UniProtKB/Swiss-Prot
  ArfGAP_dom_sf UniProtKB/Swiss-Prot
  BAR_dom UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
KEGG Report rno:619382 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93962 IMAGE-MGC_LOAD
NCBI Gene 619382 ENTREZGENE
PANTHER ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
  PTHR23180 UniProtKB/Swiss-Prot
Pfam Ank_2 UniProtKB/Swiss-Prot
  ArfGap UniProtKB/Swiss-Prot
  BAR_3 UniProtKB/Swiss-Prot
  PF00169 UniProtKB/Swiss-Prot
PhenoGen Acap2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  ARFGAP UniProtKB/Swiss-Prot
  PH_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001730 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
  ArfGap UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF103657 UniProtKB/Swiss-Prot
  SSF48403 UniProtKB/Swiss-Prot
  SSF57863 UniProtKB/Swiss-Prot
UniProt A0A0G2K4T3_RAT UniProtKB/TrEMBL
  A0A8I5ZV04_RAT UniProtKB/TrEMBL
  A0A8L2QG26 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L432_RAT UniProtKB/TrEMBL
  ACAP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Acap2  ArfGAP with coiled-coil, ankyrin repeat and PH domains 2  LOC360727  similar to Centaurin beta 2 (Cnt-b2)  Data merged from RGD:1590882 1643240 APPROVED
2008-10-15 Acap2  ArfGAP with coiled-coil, ankyrin repeat and PH domains 2  Centb2  centaurin, beta 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC360727  similar to Centaurin beta 2 (Cnt-b2)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 Centb2  centaurin, beta 2      Symbol and Name status set to provisional 70820 PROVISIONAL