Taok3 (TAO kinase 3) - Rat Genome Database

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Gene: Taok3 (TAO kinase 3) Rattus norvegicus
Analyze
Symbol: Taok3
Name: TAO kinase 3
RGD ID: 1562861
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; neuron projection morphogenesis; and regulation of MAPK cascade. Predicted to be located in lipid droplet; membrane raft; and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human TAOK3 (TAO kinase 3); PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: axotomy-related gene 357 protein; JIK; JNK/SAPK-inhibitory kinase; jun kinase-inhibitory kinase; serine/threonine-protein kinase TAO3; thousand and one amino acid protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,973,180 - 45,134,439 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1244,973,180 - 45,134,439 (-)EnsemblGRCr8
mRatBN7.21239,312,354 - 39,473,656 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,314,027 - 39,461,244 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1240,487,630 - 40,648,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01241,101,449 - 41,262,709 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,154,420 - 40,315,685 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01245,037,951 - 45,116,593 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,037,883 - 45,182,974 (-)Ensemblrn6Rnor6.0
Rnor_5.01246,857,904 - 46,936,392 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41240,502,499 - 40,583,816 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1240,955,052 - 41,034,414 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol AF  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
celastrol  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
emodin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (ISO)
Evodiamine  (ISO)
FR900359  (ISO)
furan  (EXP)
gedunin  (ISO)
gentamycin  (EXP)
glycidol  (EXP)
inulin  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methoxychlor  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10559204   PMID:10924369   PMID:11278723   PMID:16092929   PMID:17396146  


Genomics

Comparative Map Data
Taok3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,973,180 - 45,134,439 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1244,973,180 - 45,134,439 (-)EnsemblGRCr8
mRatBN7.21239,312,354 - 39,473,656 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,314,027 - 39,461,244 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1240,487,630 - 40,648,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01241,101,449 - 41,262,709 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,154,420 - 40,315,685 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01245,037,951 - 45,116,593 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,037,883 - 45,182,974 (-)Ensemblrn6Rnor6.0
Rnor_5.01246,857,904 - 46,936,392 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41240,502,499 - 40,583,816 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1240,955,052 - 41,034,414 (-)NCBICelera
Cytogenetic Map12q16NCBI
TAOK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812118,149,801 - 118,372,907 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12118,149,801 - 118,372,920 (-)Ensemblhg38GRCh38
GRCh3712118,587,606 - 118,810,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612117,071,989 - 117,295,133 (-)NCBIBuild 36Build 36hg18NCBI36
Celera12118,218,692 - 118,443,700 (-)NCBICelera
Cytogenetic Map12q24.23NCBI
HuRef12115,597,575 - 115,819,970 (-)NCBIHuRef
CHM1_112118,555,318 - 118,778,602 (-)NCBICHM1_1
T2T-CHM13v2.012118,137,047 - 118,360,176 (-)NCBIT2T-CHM13v2.0
Taok3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395117,258,180 - 117,413,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5117,258,194 - 117,413,284 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385117,120,111 - 117,275,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,120,129 - 117,275,219 (+)Ensemblmm10GRCm38
MGSCv375117,583,604 - 117,723,924 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365117,381,159 - 117,534,945 (+)NCBIMGSCv36mm8
Celera5114,223,391 - 114,369,377 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.88NCBI
Taok3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545513,103,357 - 13,211,315 (+)Ensembl
ChiLan1.0NW_00495545513,020,618 - 13,207,539 (+)NCBIChiLan1.0ChiLan1.0
TAOK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210126,216,146 - 126,439,808 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112126,212,526 - 126,436,204 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012115,730,619 - 115,954,149 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112119,109,642 - 119,332,679 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12119,109,642 - 119,226,502 (-)EnsemblpanPan2panpan1.1
TAOK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12614,534,083 - 14,712,779 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2614,534,901 - 14,631,899 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2614,527,147 - 14,711,964 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02614,795,979 - 14,974,732 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2614,797,097 - 14,974,708 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12614,760,804 - 14,939,682 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02614,833,069 - 15,012,056 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02614,868,170 - 15,053,480 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Taok3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118147,618,018 - 147,806,440 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366682,222,866 - 2,304,151 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366682,116,804 - 2,305,331 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAOK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1434,409,070 - 34,513,025 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11434,322,016 - 34,514,234 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21436,452,203 - 36,675,287 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAOK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111113,485,871 - 113,717,213 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11113,484,330 - 113,704,271 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037131,386,279 - 131,613,306 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taok3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474715,241,065 - 15,331,935 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474715,142,378 - 15,331,197 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Taok3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11636,549,936 - 36,708,850 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Taok3
820 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000001503
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)124413955852308831Rat

Markers in Region
RH132162  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21239,314,108 - 39,314,323 (+)MAPPERmRatBN7.2
Rnor_6.01245,037,978 - 45,038,192NCBIRnor6.0
Rnor_5.01246,857,931 - 46,858,145UniSTSRnor5.0
RGSC_v3.41240,502,513 - 40,502,727UniSTSRGSC3.4
Celera1240,955,134 - 40,955,348UniSTS
RH 3.4 Map12728.6UniSTS
Cytogenetic Map12q16UniSTS
RH137431  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21239,316,810 - 39,316,995 (+)MAPPERmRatBN7.2
Rnor_6.01245,040,692 - 45,040,876NCBIRnor6.0
Rnor_5.01246,860,003 - 46,860,187UniSTSRnor5.0
RGSC_v3.41240,505,247 - 40,505,431UniSTSRGSC3.4
Celera1240,957,767 - 40,957,951UniSTS
RH 3.4 Map12731.51UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001503   ⟹   ENSRNOP00000001503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1244,973,180 - 45,134,439 (-)Ensembl
mRatBN7.2 Ensembl1239,314,027 - 39,461,244 (-)Ensembl
Rnor_6.0 Ensembl1245,037,951 - 45,182,974 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089043   ⟹   ENSRNOP00000074994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1245,037,883 - 45,116,665 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134155   ⟹   ENSRNOP00000110084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1244,973,180 - 45,134,439 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000150452   ⟹   ENSRNOP00000106911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1244,973,180 - 45,134,439 (-)Ensembl
RefSeq Acc Id: NM_001024254   ⟹   NP_001019425
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81244,973,180 - 45,134,439 (-)NCBI
mRatBN7.21239,312,354 - 39,473,656 (-)NCBI
Rnor_6.01245,037,951 - 45,116,593 (-)NCBI
Rnor_5.01246,857,904 - 46,936,392 (-)NCBI
RGSC_v3.41240,502,499 - 40,583,816 (-)RGD
Celera1240,955,052 - 41,034,414 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001019425   ⟸   NM_001024254
- UniProtKB: Q53UA7 (UniProtKB/Swiss-Prot),   A6J1P6 (UniProtKB/TrEMBL),   F1LRI6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074994   ⟸   ENSRNOT00000089043
Ensembl Acc Id: ENSRNOP00000001503   ⟸   ENSRNOT00000001503
Ensembl Acc Id: ENSRNOP00000106911   ⟸   ENSRNOT00000150452
Ensembl Acc Id: ENSRNOP00000110084   ⟸   ENSRNOT00000134155
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q53UA7-F1-model_v2 AlphaFold Q53UA7 1-898 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562861 AgrOrtholog
BioCyc Gene G2FUF-19058 BioCyc
Ensembl Genes ENSRNOG00000001138 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000001503 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  TAO_STE20_kinase UniProtKB/Swiss-Prot
KEGG Report rno:304530 UniProtKB/Swiss-Prot
NCBI Gene 304530 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN UniProtKB/Swiss-Prot
  SERINE_THREONINE-PROTEIN KINASE TAO3 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Taok3 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001138 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0ABK0LSH7_RAT UniProtKB/TrEMBL
  A0ABK0LXC7_RAT UniProtKB/TrEMBL
  A6J1P6 ENTREZGENE, UniProtKB/TrEMBL
  F1LRI6 ENTREZGENE, UniProtKB/TrEMBL
  Q53UA7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Taok3  TAO kinase 3  JIK  JNK/SAPK-inhibitory kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 JIK  JNK/SAPK-inhibitory kinase      Symbol and Name status set to provisional 70820 PROVISIONAL