Wac (WW domain containing adaptor with coiled-coil) - Rat Genome Database

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Gene: Wac (WW domain containing adaptor with coiled-coil) Rattus norvegicus
Analyze
Symbol: Wac
Name: WW domain containing adaptor with coiled-coil
RGD ID: 1562407
Description: Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in several processes, including mitotic G1 DNA damage checkpoint signaling; positive regulation of TORC1 signaling; and positive regulation of metabolic process. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in DeSanto-Shinawi syndrome. Orthologous to human WAC (WW domain containing adaptor with coiled-coil); INTERACTS WITH aflatoxin B1; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC307029; RGD1562407; similar to WAC; uncharacterized protein LOC307029; WW domain-containing adapter protein with coiled-coil; WW domain-containing adaptor with coiled-coil
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Wac-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,617,702 - 60,677,771 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1760,617,544 - 60,679,267 (+)EnsemblGRCr8
mRatBN7.21755,922,686 - 55,984,286 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,923,123 - 55,982,301 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1759,092,613 - 59,151,089 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01763,095,705 - 63,154,179 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01757,235,586 - 57,293,885 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,887,606 - 60,946,630 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)Ensemblrn6Rnor6.0
Rnor_5.01762,663,721 - 62,723,083 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41764,530,450 - 64,604,845 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1757,238,053 - 57,291,859 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11827461   PMID:21329877   PMID:21811234   PMID:22354037  


Genomics

Comparative Map Data
Wac
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,617,702 - 60,677,771 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1760,617,544 - 60,679,267 (+)EnsemblGRCr8
mRatBN7.21755,922,686 - 55,984,286 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,923,123 - 55,982,301 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1759,092,613 - 59,151,089 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01763,095,705 - 63,154,179 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01757,235,586 - 57,293,885 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,887,606 - 60,946,630 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)Ensemblrn6Rnor6.0
Rnor_5.01762,663,721 - 62,723,083 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41764,530,450 - 64,604,845 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1757,238,053 - 57,291,859 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
WAC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381028,532,779 - 28,623,112 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1028,532,493 - 28,623,112 (+)Ensemblhg38GRCh38
GRCh371028,821,708 - 28,912,041 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361028,861,706 - 28,949,478 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1028,585,512 - 28,673,953 (+)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1028,539,551 - 28,629,942 (+)NCBIHuRef
CHM1_11028,821,968 - 28,912,537 (+)NCBICHM1_1
T2T-CHM13v2.01028,563,354 - 28,653,650 (+)NCBIT2T-CHM13v2.0
Wac
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,868,614 - 7,929,028 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,868,832 - 7,929,028 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38187,868,825 - 7,929,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,868,832 - 7,929,028 (+)Ensemblmm10GRCm38
MGSCv37187,868,856 - 7,929,025 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36187,869,237 - 7,927,072 (+)NCBIMGSCv36mm8
Celera187,915,935 - 7,976,189 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.62NCBI
Wac
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554622,358,842 - 2,435,628 (+)Ensembl
ChiLan1.0NW_0049554622,358,842 - 2,435,644 (+)NCBIChiLan1.0ChiLan1.0
WAC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2841,205,841 - 41,297,561 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11041,211,167 - 41,302,888 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01028,685,294 - 28,777,176 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11029,042,331 - 29,130,597 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1029,042,331 - 29,130,591 (+)EnsemblpanPan2panpan1.1
WAC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1217,504,949 - 17,588,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha215,004,769 - 15,088,966 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0215,753,171 - 15,837,460 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl215,753,598 - 15,837,473 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1215,191,803 - 15,274,633 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0215,079,183 - 15,162,408 (-)NCBIUNSW_CanFamBas_1.0
Wac
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093448,243,833 - 8,314,148 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366132,794,732 - 2,865,913 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366132,793,706 - 2,862,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WAC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1039,932,599 - 40,022,338 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11039,932,562 - 40,024,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21044,120,334 - 44,210,098 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WAC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1928,131,774 - 28,222,501 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl928,131,769 - 28,219,134 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605134,167,952 - 34,256,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wac
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248056,813,100 - 6,898,686 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Wac
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11427,947,754 - 28,008,458 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wac
178 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:61
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000058852
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174949693265155015Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat

Markers in Region
D10S1559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,981,648 - 55,981,773 (-)MAPPERmRatBN7.2
mRatBN7.262,002,659 - 2,002,784 (+)MAPPERmRatBN7.2
mRatBN7.21755,981,648 - 55,981,773 (+)MAPPERmRatBN7.2
mRatBN7.262,002,659 - 2,002,784 (-)MAPPERmRatBN7.2
mRatBN7.21811,855,180 - 11,855,305 (-)MAPPERmRatBN7.2
mRatBN7.21811,855,180 - 11,855,305 (+)MAPPERmRatBN7.2
Rnor_6.01815,628,636 - 15,628,760NCBIRnor6.0
Rnor_6.01760,887,493 - 60,887,617NCBIRnor6.0
Rnor_5.01815,402,667 - 15,402,791UniSTSRnor5.0
Rnor_5.01762,663,608 - 62,663,732UniSTSRnor5.0
RGSC_v3.4616,600,259 - 16,600,383UniSTSRGSC3.4
RGSC_v3.41812,316,769 - 12,316,893UniSTSRGSC3.4
Celera61,804,181 - 1,804,305UniSTS
Celera1811,869,520 - 11,869,644UniSTS
Cytogenetic Map18p12UniSTS
Cytogenetic Map17q12.1UniSTS
RH127461  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,984,082 - 55,984,262 (-)MAPPERmRatBN7.2
Rnor_6.01760,883,226 - 60,883,405NCBIRnor6.0
Rnor_5.01762,659,952 - 62,660,131UniSTSRnor5.0
RGSC_v3.41764,593,064 - 64,593,243UniSTSRGSC3.4
Celera1757,297,834 - 57,298,013UniSTS
RH 3.4 Map17562.7UniSTS
Cytogenetic Map17q12.1UniSTS
RH144108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,957,797 - 55,957,954 (-)MAPPERmRatBN7.2
Rnor_6.01760,911,882 - 60,912,038NCBIRnor6.0
Rnor_5.01762,688,335 - 62,688,491UniSTSRnor5.0
RGSC_v3.41764,565,803 - 64,565,959UniSTSRGSC3.4
Celera1757,272,064 - 57,272,220UniSTS
RH 3.4 Map17562.3UniSTS
Cytogenetic Map17q12.1UniSTS
AA850129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.262,003,555 - 2,003,740 (-)MAPPERmRatBN7.2
Rnor_6.01760,886,537 - 60,886,721NCBIRnor6.0
Rnor_6.01760,884,759 - 60,884,947NCBIRnor6.0
Rnor_5.01762,662,651 - 62,662,836NCBIRnor5.0
Rnor_5.01762,661,484 - 62,661,673NCBIRnor5.0
RGSC_v3.41764,591,525 - 64,591,710UniSTSRGSC3.4
RGSC_v3.4616,599,303 - 16,599,487UniSTSRGSC3.4
Celera61,805,077 - 1,805,261UniSTS
RH 3.4 Map17572.2UniSTS
Cytogenetic Map17q12.1UniSTS
Cytogenetic Map18p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010058876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB574169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000058852   ⟹   ENSRNOP00000055641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,617,544 - 60,677,314 (+)Ensembl
mRatBN7.2 Ensembl1755,923,123 - 55,981,660 (+)Ensembl
Rnor_6.0 Ensembl1760,888,017 - 60,946,426 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100553   ⟹   ENSRNOP00000110310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,617,577 - 60,679,267 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116963   ⟹   ENSRNOP00000082342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,617,918 - 60,677,314 (+)Ensembl
mRatBN7.2 Ensembl1755,923,282 - 55,982,301 (+)Ensembl
RefSeq Acc Id: NM_001270417   ⟹   NP_001257346
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,111 - 60,676,640 (+)NCBI
mRatBN7.21755,923,123 - 55,981,660 (+)NCBI
Rnor_6.01760,887,606 - 60,946,630 (-)NCBI
Rnor_5.01762,663,721 - 62,723,083 (-)NCBI
Celera1757,238,053 - 57,291,859 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095730   ⟹   XP_038951658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
mRatBN7.21755,922,946 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_039095733   ⟹   XP_038951661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,789 - 60,677,771 (+)NCBI
mRatBN7.21755,922,686 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_039095734   ⟹   XP_038951662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,458 - 60,677,771 (+)NCBI
mRatBN7.21755,923,474 - 55,984,286 (+)NCBI
RefSeq Acc Id: XM_039095738   ⟹   XP_038951666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
mRatBN7.21755,922,947 - 55,982,791 (+)NCBI
RefSeq Acc Id: XM_063276462   ⟹   XP_063132532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276463   ⟹   XP_063132533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276464   ⟹   XP_063132534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276465   ⟹   XP_063132535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276466   ⟹   XP_063132536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,918 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276467   ⟹   XP_063132537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,181 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276468   ⟹   XP_063132538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,702 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276469   ⟹   XP_063132539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,458 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276470   ⟹   XP_063132540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,445 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276471   ⟹   XP_063132541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276472   ⟹   XP_063132542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,617,918 - 60,677,771 (+)NCBI
RefSeq Acc Id: XM_063276473   ⟹   XP_063132543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,445 - 60,677,771 (+)NCBI
RefSeq Acc Id: XR_010058875
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,666,509 (+)NCBI
RefSeq Acc Id: XR_010058876
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,618,222 - 60,666,509 (+)NCBI
RefSeq Acc Id: NP_001257346   ⟸   NM_001270417
- UniProtKB: G3XEV5 (UniProtKB/TrEMBL),   F1LW69 (UniProtKB/TrEMBL),   A6KPM9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000055641   ⟸   ENSRNOT00000058852
RefSeq Acc Id: XP_038951661   ⟸   XM_039095733
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951658   ⟸   XM_039095730
- Peptide Label: isoform X3
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951666   ⟸   XM_039095738
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZWU8 (UniProtKB/TrEMBL),   A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951662   ⟸   XM_039095734
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082342   ⟸   ENSRNOT00000116963
RefSeq Acc Id: XP_063132538   ⟸   XM_063276468
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132536   ⟸   XM_063276466
- Peptide Label: isoform X6
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132542   ⟸   XM_063276472
- Peptide Label: isoform X11
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132537   ⟸   XM_063276467
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132532   ⟸   XM_063276462
- Peptide Label: isoform X1
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132533   ⟸   XM_063276463
- Peptide Label: isoform X2
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132534   ⟸   XM_063276464
- Peptide Label: isoform X4
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132535   ⟸   XM_063276465
- Peptide Label: isoform X5
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132541   ⟸   XM_063276471
- Peptide Label: isoform X9
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132540   ⟸   XM_063276470
- Peptide Label: isoform X8
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132543   ⟸   XM_063276473
- Peptide Label: isoform X12
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132539   ⟸   XM_063276469
- Peptide Label: isoform X7
- UniProtKB: A6KPM9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110310   ⟸   ENSRNOT00000100553
Protein Domains
WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LW69-F1-model_v2 AlphaFold F1LW69 1-644 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562407 AgrOrtholog
BioCyc Gene G2FUF-8961 BioCyc
Ensembl Genes ENSRNOG00000018698 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058852 ENTREZGENE
  ENSRNOT00000058852.6 UniProtKB/TrEMBL
  ENSRNOT00000100553 ENTREZGENE
  ENSRNOT00000100553.2 UniProtKB/TrEMBL
  ENSRNOT00000116963 ENTREZGENE
  ENSRNOT00000116963.2 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
InterPro WAC UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  WW_Rsp5_WWP UniProtKB/TrEMBL
KEGG Report rno:307029 UniProtKB/TrEMBL
NCBI Gene 307029 ENTREZGENE
PANTHER PTHR15911 UniProtKB/TrEMBL
  WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL UniProtKB/TrEMBL
Pfam PF00397 UniProtKB/TrEMBL
PhenoGen Wac PhenoGen
PROSITE WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018698 RatGTEx
SMART SM00456 UniProtKB/TrEMBL
Superfamily-SCOP WW_Rsp5_WWP UniProtKB/TrEMBL
UniProt A0A8I5ZWU8 ENTREZGENE
  A0ABK0LYH3_RAT UniProtKB/TrEMBL
  A0ABZ3NNR9_RAT UniProtKB/TrEMBL
  A6KPM9 ENTREZGENE, UniProtKB/TrEMBL
  F1LW69 ENTREZGENE, UniProtKB/TrEMBL
  G3XEV5 ENTREZGENE
UniProt Secondary A0A8I5ZWU8 UniProtKB/TrEMBL
  G3XEV5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-29 Wac  WW domain containing adaptor with coiled-coil  RGD1562407  similar to WAC  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562407  similar to WAC   RGD1562407_predicted  similar to WAC (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562407_predicted  similar to WAC (predicted)  LOC307029  similar to WAC  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307029  similar to WAC      Symbol and Name status set to provisional 70820 PROVISIONAL