C11h3orf70 (similar to human chromosome 3 open reading frame 70) - Rat Genome Database

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Gene: C11h3orf70 (similar to human chromosome 3 open reading frame 70) Rattus norvegicus
Analyze
Symbol: C11h3orf70
Name: similar to human chromosome 3 open reading frame 70
RGD ID: 1562339
Description: Predicted to be involved in nervous system development. Orthologous to human C3orf70 (chromosome 3 open reading frame 70); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498107; RGD1562339; UPF0524 protein C3orf70 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,850,327 - 92,900,608 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1192,850,327 - 92,900,608 (+)EnsemblGRCr8
mRatBN7.21179,345,857 - 79,396,140 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1179,345,304 - 79,396,142 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1188,077,790 - 88,128,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,731,427 - 80,781,706 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01179,792,132 - 79,842,410 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,048,441 - 83,098,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,048,636 - 83,094,372 (+)Ensemblrn6Rnor6.0
Rnor_5.01186,127,852 - 86,177,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41181,578,580 - 81,625,179 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1178,196,752 - 78,247,088 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C11h3orf70
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,850,327 - 92,900,608 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1192,850,327 - 92,900,608 (+)EnsemblGRCr8
mRatBN7.21179,345,857 - 79,396,140 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1179,345,304 - 79,396,142 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1188,077,790 - 88,128,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,731,427 - 80,781,706 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01179,792,132 - 79,842,410 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,048,441 - 83,098,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,048,636 - 83,094,372 (+)Ensemblrn6Rnor6.0
Rnor_5.01186,127,852 - 86,177,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41181,578,580 - 81,625,179 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1178,196,752 - 78,247,088 (+)NCBICelera
Cytogenetic Map11q23NCBI
C3orf70
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,076,838 - 185,153,060 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3185,076,838 - 185,153,060 (-)Ensemblhg38GRCh38
GRCh373184,794,626 - 184,870,848 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,278,532 - 186,353,496 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3183,242,851 - 183,317,793 (-)NCBICelera
Cytogenetic Map3q27.2NCBI
HuRef3182,205,872 - 182,280,828 (-)NCBIHuRef
CHM1_13184,758,702 - 184,833,694 (-)NCBICHM1_1
T2T-CHM13v2.03187,892,871 - 187,969,068 (-)NCBIT2T-CHM13v2.0
2510009E07Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391621,467,795 - 21,513,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1621,467,795 - 21,513,415 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381621,649,045 - 21,694,665 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1621,649,045 - 21,694,665 (-)Ensemblmm10GRCm38
MGSCv371621,649,118 - 21,694,738 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361621,563,028 - 21,608,597 (-)NCBIMGSCv36mm8
Celera1622,216,677 - 22,262,311 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1612.8NCBI
CUNH3orf70
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542022,426,369 - 22,493,624 (+)Ensembl
ChiLan1.0NW_00495542022,426,369 - 22,493,624 (+)NCBIChiLan1.0ChiLan1.0
C2H3orf70
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22182,954,404 - 183,030,160 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13182,959,120 - 183,034,281 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03182,115,285 - 182,190,975 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13190,596,286 - 190,668,551 (-)NCBIPanPan1.1PanPan1.1panPan2
C34H3orf70
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,907,247 - 17,985,399 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,911,682 - 17,985,197 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3421,992,368 - 22,071,019 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03417,815,383 - 17,894,109 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,817,633 - 17,893,978 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13417,851,545 - 17,930,199 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03417,847,419 - 17,926,261 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03418,077,057 - 18,155,757 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH3orf70
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602118,665,371 - 118,741,243 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365784,757,219 - 4,833,122 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365784,757,225 - 4,833,097 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C13H3orf70
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,958,347 - 123,058,655 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113122,958,339 - 123,058,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213132,571,127 - 132,581,423 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C15H3orf70
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1154,264,112 - 4,339,224 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl154,266,930 - 4,337,613 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606313,023,197 - 13,100,084 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH3orf70
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473071,455,517 - 71,534,832 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473071,431,449 - 71,534,838 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C4H3orf70
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v146,320,320 - 6,367,884 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000002408
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
D11Rat103  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,371,857 - 79,372,066 (+)MAPPERmRatBN7.2
Rnor_6.01183,074,472 - 83,074,680NCBIRnor6.0
Rnor_5.01186,153,919 - 86,154,127UniSTSRnor5.0
RGSC_v3.41181,604,587 - 81,604,796RGDRGSC3.4
RGSC_v3.41181,604,588 - 81,604,796UniSTSRGSC3.4
Celera1178,222,788 - 78,222,996UniSTS
RGSC_v3.11181,662,177 - 81,662,385RGD
RH 3.4 Map11654.3UniSTS
RH 3.4 Map11654.3RGD
SHRSP x BN Map1136.5499UniSTS
SHRSP x BN Map1136.5499RGD
Cytogenetic Map11q23UniSTS
RH132670  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,395,709 - 79,395,915 (+)MAPPERmRatBN7.2
Rnor_6.01183,098,219 - 83,098,424NCBIRnor6.0
Rnor_5.01186,177,444 - 86,177,649UniSTSRnor5.0
RGSC_v3.41181,629,026 - 81,629,231UniSTSRGSC3.4
Celera1178,246,658 - 78,246,863UniSTS
RH 3.4 Map11653.1UniSTS
Cytogenetic Map11q23UniSTS
AI501553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,392,435 - 79,392,580 (+)MAPPERmRatBN7.2
Rnor_6.01183,094,945 - 83,095,089NCBIRnor6.0
Rnor_5.01186,174,170 - 86,174,314UniSTSRnor5.0
RGSC_v3.41181,625,752 - 81,625,896UniSTSRGSC3.4
Celera1178,243,384 - 78,243,528UniSTS
RH 3.4 Map11654.1UniSTS
Cytogenetic Map11q23UniSTS
RH134678  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,393,915 - 79,394,116 (+)MAPPERmRatBN7.2
Rnor_6.01183,096,425 - 83,096,625NCBIRnor6.0
Rnor_5.01186,175,650 - 86,175,850UniSTSRnor5.0
RGSC_v3.41181,627,232 - 81,627,432UniSTSRGSC3.4
Celera1178,244,864 - 78,245,064UniSTS
RH 3.4 Map1695.6UniSTS
Cytogenetic Map11q23UniSTS
RH134753  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,394,523 - 79,394,713 (+)MAPPERmRatBN7.2
Rnor_6.01183,097,033 - 83,097,222NCBIRnor6.0
Rnor_5.01186,176,258 - 86,176,447UniSTSRnor5.0
RGSC_v3.41181,627,840 - 81,628,029UniSTSRGSC3.4
Celera1178,245,472 - 78,245,661UniSTS
RH 3.4 Map11654.5UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 13 81 217 91 90 59 115 59 6 434 239 22 195 108 124 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000002408   ⟹   ENSRNOP00000002408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1183,048,636 - 83,094,372 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104615   ⟹   ENSRNOP00000087111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1192,850,327 - 92,900,608 (+)Ensembl
mRatBN7.2 Ensembl1179,345,304 - 79,396,142 (+)Ensembl
RefSeq Acc Id: NM_001398864   ⟹   NP_001385793
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81192,850,327 - 92,900,608 (+)NCBI
mRatBN7.21179,345,857 - 79,396,140 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087111
  ENSRNOP00000087111.1
Ensembl Acc Id: ENSRNOP00000002408   ⟸   ENSRNOT00000002408
Ensembl Acc Id: ENSRNOP00000087111   ⟸   ENSRNOT00000104615
RefSeq Acc Id: NP_001385793   ⟸   NM_001398864
- UniProtKB: A0A8I6A3M1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC80-F1-model_v2 AlphaFold D4AC80 1-246 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562339 AgrOrtholog
BioCyc Gene G2FUF-20786 BioCyc
Ensembl Genes ENSRNOG00000001767 Ensembl
  ENSRNOG00000063811 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000104615 ENTREZGENE
  ENSRNOT00000104615.2 UniProtKB/TrEMBL
InterPro UPF0524_fam UniProtKB/TrEMBL
NCBI Gene 498107 ENTREZGENE
PANTHER PTHR31785 UniProtKB/TrEMBL
  UPF0524 PROTEIN C3ORF70 UniProtKB/TrEMBL
Pfam UPF0524 UniProtKB/TrEMBL
PhenoGen C11h3orf70 PhenoGen
RatGTEx ENSRNOG00000001767 RatGTEx
  ENSRNOG00000063811 RatGTEx
UniProt A0A8I6A3M1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-12 C11h3orf70  similar to human chromosome 3 open reading frame 70  RGD1562339  RGD1562339  Name and Symbol changed 629549 APPROVED
2022-06-02 RGD1562339  RGD1562339  RGD1562339  RGD1562339  Data merged from RGD:149736483 737654 PROVISIONAL
2021-08-09 RGD1562339  RGD1562339      Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1562339  RGD1562339   RGD1562339_predicted  RGD1562339 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562339_predicted  RGD1562339 (predicted)  LOC498107  LOC498107  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498107  LOC498107      Symbol and Name status set to provisional 70820 PROVISIONAL