Mcmdc2 (minichromosome maintenance domain containing 2) - Rat Genome Database

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Pathways
Gene: Mcmdc2 (minichromosome maintenance domain containing 2) Rattus norvegicus
Analyze
Symbol: Mcmdc2
Name: minichromosome maintenance domain containing 2
RGD ID: 1561068
Description: Predicted to enable ATP binding activity and DNA binding activity. Predicted to be involved in double-strand break repair via break-induced replication. Predicted to act upstream of or within meiosis I cell cycle process; oogenesis; and spermatogenesis. Predicted to be active in nucleus. Orthologous to human MCMDC2 (minichromosome maintenance domain containing 2); INTERACTS WITH (S)-nicotine; 6-propyl-2-thiouracil; acetamiprid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC500392; MCM domain-containing protein 2; MCM domain-containing protein C8orf45 homolog; minichromosome maintenance complex component-like; minichromosome maintenance domain-containing protein 2; similar to hypothetical protein FLJ25692; uncharacterized protein C8orf45 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,071,609 - 14,120,435 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,080,968 - 14,120,351 (-)EnsemblGRCr8
mRatBN7.259,291,967 - 9,337,526 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,298,101 - 9,338,300 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx511,454,559 - 11,494,044 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0513,084,457 - 13,123,993 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0512,789,227 - 12,828,713 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.058,973,861 - 9,039,616 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl58,978,010 - 9,038,594 (-)Ensemblrn6Rnor6.0
Rnor_5.0513,781,014 - 13,839,762 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.458,842,432 - 8,881,827 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera58,810,709 - 8,849,895 (-)NCBICelera
Cytogenetic Map5q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:27760146  


Genomics

Comparative Map Data
Mcmdc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,071,609 - 14,120,435 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,080,968 - 14,120,351 (-)EnsemblGRCr8
mRatBN7.259,291,967 - 9,337,526 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,298,101 - 9,338,300 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx511,454,559 - 11,494,044 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0513,084,457 - 13,123,993 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0512,789,227 - 12,828,713 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.058,973,861 - 9,039,616 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl58,978,010 - 9,038,594 (-)Ensemblrn6Rnor6.0
Rnor_5.0513,781,014 - 13,839,762 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.458,842,432 - 8,881,827 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera58,810,709 - 8,849,895 (-)NCBICelera
Cytogenetic Map5q11NCBI
MCMDC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38866,870,771 - 66,926,382 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl866,870,749 - 66,922,048 (+)Ensemblhg38GRCh38
GRCh37867,783,006 - 67,834,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36867,948,884 - 67,976,570 (+)NCBIBuild 36Build 36hg18NCBI36
Celera863,776,478 - 63,827,777 (+)NCBICelera
Cytogenetic Map8q13.1NCBI
HuRef863,275,571 - 63,326,869 (+)NCBIHuRef
CHM1_1867,837,961 - 67,889,304 (+)NCBICHM1_1
T2T-CHM13v2.0867,297,252 - 67,352,914 (+)NCBIT2T-CHM13v2.0
Mcmdc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3919,978,863 - 10,011,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl19,978,863 - 10,012,310 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3819,906,157 - 9,943,606 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,908,638 - 9,942,085 (+)Ensemblmm10GRCm38
MGSCv3719,898,719 - 9,931,035 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3619,896,933 - 9,926,168 (+)NCBIMGSCv36mm8
Celera19,881,469 - 9,914,977 (+)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.19NCBI
Mcmdc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544412,348,543 - 12,382,769 (-)Ensembl
ChiLan1.0NW_00495544412,348,537 - 12,382,769 (-)NCBIChiLan1.0ChiLan1.0
MCMDC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2782,606,924 - 82,685,993 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1858,249,270 - 58,328,279 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0863,412,462 - 63,465,258 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1865,079,264 - 65,128,147 (+)NCBIPanPan1.1PanPan1.1panPan2
MCMDC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,424,088 - 16,462,094 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,426,318 - 16,460,599 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2916,739,713 - 16,777,699 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02916,504,173 - 16,542,352 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2916,503,756 - 16,540,857 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12916,536,436 - 16,574,575 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02916,636,010 - 16,674,434 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02916,892,562 - 16,930,779 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mcmdc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,602,488 - 67,607,766 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364967,171,413 - 7,182,771 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364967,149,501 - 7,182,771 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCMDC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl467,847,817 - 67,895,867 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1467,850,585 - 67,892,438 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2473,908,711 - 73,952,722 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCMDC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1862,742,176 - 62,790,994 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl862,745,855 - 62,790,143 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603978,709,912 - 78,763,056 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcmdc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474424,425,515 - 24,471,470 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474424,422,656 - 24,483,365 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcmdc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11144,668,914 - 144,702,800 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mcmdc2
367 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:251
Count of miRNA genes:157
Interacting mature miRNAs:192
Transcripts:ENSRNOT00000030053
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
631827Alc4Alcohol consumption QTL 43.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)51297048025683802Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 86 59 6 348 186 11 143 79 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000030053   ⟹   ENSRNOP00000037494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,080,968 - 14,120,351 (-)Ensembl
mRatBN7.2 Ensembl59,298,101 - 9,338,300 (-)Ensembl
Rnor_6.0 Ensembl58,979,961 - 9,038,594 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082023   ⟹   ENSRNOP00000070565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,082,176 - 14,120,351 (-)Ensembl
mRatBN7.2 Ensembl59,299,309 - 9,337,485 (-)Ensembl
Rnor_6.0 Ensembl58,978,010 - 9,035,811 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109775   ⟹   ENSRNOP00000080811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,110,435 - 14,120,351 (-)Ensembl
mRatBN7.2 Ensembl59,327,569 - 9,337,485 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155481   ⟹   ENSRNOP00000112584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,080,968 - 14,117,774 (-)Ensembl
RefSeq Acc Id: NM_001024340   ⟹   NP_001019511
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,351 (-)NCBI
mRatBN7.259,298,100 - 9,337,485 (-)NCBI
Rnor_6.058,979,960 - 9,038,594 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
RGSC_v3.458,842,432 - 8,881,827 (-)RGD
Celera58,810,709 - 8,849,895 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237781   ⟹   XP_006237843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,179 (-)NCBI
mRatBN7.259,299,153 - 9,337,309 (-)NCBI
Rnor_6.058,980,202 - 9,039,612 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237782   ⟹   XP_006237844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,399 (-)NCBI
mRatBN7.259,299,153 - 9,337,526 (-)NCBI
Rnor_6.058,980,202 - 9,039,612 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237784   ⟹   XP_006237846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,179 (-)NCBI
mRatBN7.259,299,153 - 9,337,309 (-)NCBI
Rnor_6.058,980,202 - 9,039,613 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237785   ⟹   XP_006237847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,179 (-)NCBI
mRatBN7.259,299,153 - 9,337,309 (-)NCBI
Rnor_6.058,980,202 - 9,039,616 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237787   ⟹   XP_006237849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,071,609 - 14,120,179 (-)NCBI
mRatBN7.259,291,967 - 9,337,309 (-)NCBI
Rnor_6.058,973,861 - 9,039,609 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237788   ⟹   XP_006237850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,179 (-)NCBI
mRatBN7.259,299,228 - 9,337,309 (-)NCBI
Rnor_6.058,980,202 - 9,039,599 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237789   ⟹   XP_006237851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,084,181 - 14,120,179 (-)NCBI
mRatBN7.259,301,364 - 9,337,309 (-)NCBI
Rnor_6.058,983,255 - 9,039,598 (-)NCBI
Rnor_5.0513,781,014 - 13,839,762 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110522   ⟹   XP_038966450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,399 (-)NCBI
mRatBN7.259,299,153 - 9,337,526 (-)NCBI
RefSeq Acc Id: XM_039110523   ⟹   XP_038966451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,179 (-)NCBI
mRatBN7.259,299,153 - 9,337,309 (-)NCBI
RefSeq Acc Id: XM_039110524   ⟹   XP_038966452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,114,340 (-)NCBI
mRatBN7.259,299,153 - 9,331,473 (-)NCBI
RefSeq Acc Id: XM_063288170   ⟹   XP_063144240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,120,435 (-)NCBI
RefSeq Acc Id: XM_063288171   ⟹   XP_063144241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,071,609 - 14,120,435 (-)NCBI
RefSeq Acc Id: XM_063288173   ⟹   XP_063144243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,084,181 - 14,120,435 (-)NCBI
RefSeq Acc Id: XM_063288174   ⟹   XP_063144244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,117,284 (-)NCBI
RefSeq Acc Id: XM_063288175   ⟹   XP_063144245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,080,967 - 14,117,285 (-)NCBI
RefSeq Acc Id: NP_001019511   ⟸   NM_001024340
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006237849   ⟸   XM_006237787
- Peptide Label: isoform X6
- UniProtKB: A6JFF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237844   ⟸   XM_006237782
- Peptide Label: isoform X1
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot),   R9PXX4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237846   ⟸   XM_006237784
- Peptide Label: isoform X2
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006237847   ⟸   XM_006237785
- Peptide Label: isoform X3
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006237850   ⟸   XM_006237788
- Peptide Label: isoform X8
- UniProtKB: A6JFF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237843   ⟸   XM_006237781
- Peptide Label: isoform X1
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot),   R9PXX4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237851   ⟸   XM_006237789
- Peptide Label: isoform X9
- UniProtKB: A6JFF7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070565   ⟸   ENSRNOT00000082023
Ensembl Acc Id: ENSRNOP00000037494   ⟸   ENSRNOT00000030053
RefSeq Acc Id: XP_038966450   ⟸   XM_039110522
- Peptide Label: isoform X2
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038966451   ⟸   XM_039110523
- Peptide Label: isoform X5
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038966452   ⟸   XM_039110524
- Peptide Label: isoform X11
Ensembl Acc Id: ENSRNOP00000080811   ⟸   ENSRNOT00000109775
RefSeq Acc Id: XP_063144241   ⟸   XM_063288171
- Peptide Label: isoform X7
- UniProtKB: A6JFF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144240   ⟸   XM_063288170
- Peptide Label: isoform X4
- UniProtKB: Q5XI14 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063144245   ⟸   XM_063288175
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063144244   ⟸   XM_063288174
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063144243   ⟸   XM_063288173
- Peptide Label: isoform X10
- UniProtKB: A6JFF7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112584   ⟸   ENSRNOT00000155481
Protein Domains
MCM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI14-F1-model_v2 AlphaFold Q5XI14 1-681 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693535
Promoter ID:EPDNEW_R4060
Type:single initiation site
Name:Mcmdc2_1
Description:minichromosome maintenance domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.059,038,600 - 9,038,660EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561068 AgrOrtholog
BioCyc Gene G2FUF-42206 BioCyc
Ensembl Genes ENSRNOG00000021702 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000030053 ENTREZGENE
  ENSRNOT00000155481 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7131459 IMAGE-MGC_LOAD
InterPro MCM UniProtKB/Swiss-Prot
  MCM_lid UniProtKB/Swiss-Prot
  NA-bd_OB-fold UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:500392 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95183 IMAGE-MGC_LOAD
NCBI Gene 500392 ENTREZGENE
PANTHER MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
  PTHR11630 UniProtKB/Swiss-Prot
Pfam MCM_lid UniProtKB/Swiss-Prot
PhenoGen Mcmdc2 PhenoGen
RatGTEx ENSRNOG00000021702 RatGTEx
SMART MCM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50249 UniProtKB/Swiss-Prot
UniProt A0A0G2JY91_RAT UniProtKB/TrEMBL
  A0A8I5ZR46_RAT UniProtKB/TrEMBL
  A0ABK0M112_RAT UniProtKB/TrEMBL
  A6JFF7 ENTREZGENE, UniProtKB/TrEMBL
  MCMD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  R9PXX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-18 Mcmdc2  minichromosome maintenance domain containing 2  LOC500392  similar to hypothetical protein FLJ25692  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC500392  similar to hypothetical protein FLJ25692      Symbol and Name status set to provisional 70820 PROVISIONAL