Dnah5 (dynein, axonemal, heavy chain 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dnah5 (dynein, axonemal, heavy chain 5) Rattus norvegicus
Analyze
Symbol: Dnah5
Name: dynein, axonemal, heavy chain 5
RGD ID: 1560828
Description: Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility and outer dynein arm assembly. Predicted to act upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and lateral ventricle development. Predicted to be located in 9+0 motile cilium; axoneme; and glial cell projection. Predicted to be part of outer dynein arm. Predicted to be active in 9+2 motile cilium. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Orthologous to human DNAH5 (dynein axonemal heavy chain 5); INTERACTS WITH ammonium chloride; arsane; arsenic atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: axonemal beta dynein heavy chain 5; ciliary dynein heavy chain 5; DLP5; Dnahc5; Dnahc8; dynein axonemal heavy chain 5; dynein heavy chain; dynein heavy chain 5, axonemal; dynein-like prot ein 5; dynein-like protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,668,182 - 80,985,918 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl280,668,208 - 80,985,914 (+)EnsemblGRCr8
mRatBN7.2278,937,788 - 79,255,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd280,972,305 - 81,234,029 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive281,006,008 - 81,267,703 (+)NCBILyon_Normotensive
Lyon_Hypertensive280,879,289 - 81,141,020 (+)NCBILyon_Hypertensive
F344_StmMcwi280,681,302 - 80,942,995 (+)NCBIF344_StmMcwi
Rnor_6.0280,947,730 - 81,143,997 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0281,159,060 - 81,337,560 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)Ensemblrn6Rnor6.0
Rnor_5.02100,825,558 - 101,002,352 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.02100,627,199 - 100,809,390 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4280,126,196 - 80,390,674 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera274,613,354 - 74,877,574 (+)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
9+0 motile cilium  (IEA,ISO)
9+2 motile cilium  (IBA,IEA,ISO)
axonemal dynein complex  (IEA,ISO)
axoneme  (IEA,ISO,ISS)
cytoplasm  (IEA,ISO)
dynein complex  (IEA)
extracellular region  (IEA)
microtubule  (IEA)
motile cilium  (IEA,ISO,ISS)
outer dynein arm  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Olbrich H, etal., Nat Genet. 2002 Feb;30(2):143-4. Epub 2002 Jan 14.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Identification and molecular evolution of new dynein-like protein sequences in rat brain. Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93.
9. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
Additional References at PubMed
PMID:11062149   PMID:11912187   PMID:15750039   PMID:16492982   PMID:16627867   PMID:17515466   PMID:18492703   PMID:18950741   PMID:19222235   PMID:22499950   PMID:23261302   PMID:23849778  
PMID:24203976   PMID:25192045   PMID:25807483   PMID:26387594   PMID:26909801   PMID:27353389   PMID:28289722   PMID:29916806   PMID:31178125   PMID:32357304  


Genomics

Comparative Map Data
Dnah5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,668,182 - 80,985,918 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl280,668,208 - 80,985,914 (+)EnsemblGRCr8
mRatBN7.2278,937,788 - 79,255,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd280,972,305 - 81,234,029 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive281,006,008 - 81,267,703 (+)NCBILyon_Normotensive
Lyon_Hypertensive280,879,289 - 81,141,020 (+)NCBILyon_Hypertensive
F344_StmMcwi280,681,302 - 80,942,995 (+)NCBIF344_StmMcwi
Rnor_6.0280,947,730 - 81,143,997 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0281,159,060 - 81,337,560 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)Ensemblrn6Rnor6.0
Rnor_5.02100,825,558 - 101,002,352 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.02100,627,199 - 100,809,390 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4280,126,196 - 80,390,674 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera274,613,354 - 74,877,574 (+)NCBICelera
Cytogenetic Map2q22NCBI
DNAH5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38513,690,328 - 14,011,818 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl513,690,328 - 14,011,818 (-)Ensemblhg38GRCh38
GRCh37513,690,437 - 13,944,797 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36513,745,039 - 13,997,589 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34513,745,038 - 13,997,589NCBI
Celera513,715,619 - 13,969,162 (-)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef513,661,841 - 13,916,517 (-)NCBIHuRef
CHM1_1513,690,308 - 13,944,156 (-)NCBICHM1_1
T2T-CHM13v2.0513,627,358 - 13,948,914 (-)NCBIT2T-CHM13v2.0
Dnah5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391528,155,000 - 28,472,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1528,203,898 - 28,472,198 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381528,154,854 - 28,472,045 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1528,203,752 - 28,472,052 (+)Ensemblmm10GRCm38
MGSCv371528,133,521 - 28,401,800 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361528,148,355 - 28,415,259 (+)NCBIMGSCv36mm8
Celera1528,952,222 - 29,215,703 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map1510.9NCBI
Dnah5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,106,410 - 3,353,502 (-)Ensembl
ChiLan1.0NW_0049554263,105,631 - 3,406,587 (-)NCBIChiLan1.0ChiLan1.0
DNAH5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2413,914,183 - 14,246,527 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1512,067,789 - 12,400,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0513,989,114 - 14,316,855 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1513,833,309 - 14,159,871 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl513,851,391 - 14,093,358 (-)EnsemblpanPan2panpan1.1
DNAH5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.134816,088 - 1,040,052 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl34805,455 - 1,038,273 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha345,235,833 - 5,530,906 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.034649,213 - 944,561 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl34649,200 - 944,407 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.134663,314 - 958,206 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.034661,426 - 955,971 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.034904,270 - 1,199,480 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnah5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213233,673,500 - 233,953,547 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366652,314,175 - 2,545,579 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366652,267,272 - 2,545,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl163,114,273 - 3,430,341 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1163,114,267 - 3,366,189 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2163,466,224 - 3,706,296 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1413,401,980 - 13,718,900 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl413,401,092 - 13,652,755 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606414,822,926 - 15,141,477 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnah5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475110,799,892 - 11,050,403 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475110,799,102 - 11,110,180 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnah5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13152,289,658 - 152,591,007 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnah5
2139 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:177
Interacting mature miRNAs:200
Transcripts:ENSRNOT00000017372, ENSRNOT00000074252, ENSRNOT00000074689
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)261556902106556902Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)261051883104684275Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)261051541105724065Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)278269809104744824Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)261051541105724065Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260861391105861391Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat

Markers in Region
D2Uwm31  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8280,728,051 - 80,728,244 (+)Marker Load Pipeline
mRatBN7.2278,997,662 - 78,997,855 (+)MAPPERmRatBN7.2
Rnor_6.0280,964,992 - 80,965,184NCBIRnor6.0
Rnor_5.02100,630,972 - 100,631,164UniSTSRnor5.0
RGSC_v3.4280,130,990 - 80,131,182UniSTSRGSC3.4
Celera274,630,894 - 74,631,086UniSTS
RGSC_v3.1280,075,951 - 80,076,144RGD
Cytogenetic Map2q22UniSTS
AU048434  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8280,776,807 - 80,777,110 (+)Marker Load Pipeline
mRatBN7.2279,046,420 - 79,046,719 (+)MAPPERmRatBN7.2
Rnor_6.0281,013,978 - 81,014,276NCBIRnor6.0
Rnor_5.02100,679,921 - 100,680,219UniSTSRnor5.0
RGSC_v3.4280,180,056 - 80,180,354UniSTSRGSC3.4
Celera274,679,580 - 74,679,878UniSTS
Cytogenetic Map2q22UniSTS
AU049271  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8280,765,982 - 80,766,199 (+)Marker Load Pipeline
mRatBN7.2279,035,595 - 79,035,812 (+)MAPPERmRatBN7.2
Rnor_6.0281,003,174 - 81,003,390NCBIRnor6.0
Rnor_5.02100,669,154 - 100,669,370UniSTSRnor5.0
RGSC_v3.4280,168,927 - 80,169,143UniSTSRGSC3.4
Celera274,668,824 - 74,669,040UniSTS
Cytogenetic Map2q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 9 60 151 57 56 27 14 27 6 194 104 10 123 49 81 29 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000074689   ⟹   ENSRNOP00000065896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl278,980,771 - 79,237,702 (+)Ensembl
Rnor_6.0 Ensembl280,948,658 - 81,143,447 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098157   ⟹   ENSRNOP00000085962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,711,186 - 80,985,914 (+)Ensembl
mRatBN7.2 Ensembl278,980,771 - 79,254,890 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101312   ⟹   ENSRNOP00000078949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,668,208 - 80,985,914 (+)Ensembl
mRatBN7.2 Ensembl278,937,800 - 79,254,890 (+)Ensembl
RefSeq Acc Id: NM_001419569   ⟹   NP_001406498
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,711,186 - 80,985,914 (+)NCBI
mRatBN7.2278,980,794 - 79,255,551 (+)NCBI
Dahl_SR_JrHsd280,972,305 - 81,234,029 (+)NCBI
Lyon_Normotensive281,006,008 - 81,267,703 (+)NCBI
Lyon_Hypertensive280,879,289 - 81,141,020 (+)NCBI
F344_StmMcwi280,681,302 - 80,942,995 (+)NCBI
RefSeq Acc Id: XM_039103563   ⟹   XP_038959491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,668,182 - 80,985,918 (+)NCBI
mRatBN7.2278,937,788 - 79,254,088 (+)NCBI
RefSeq Acc Id: XM_063281529   ⟹   XP_063137599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,711,002 - 80,985,918 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406498 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959491 (Get FASTA)   NCBI Sequence Viewer  
  XP_063137599 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52801 (Get FASTA)   NCBI Sequence Viewer  
  BAA05504 (Get FASTA)   NCBI Sequence Viewer  
  EDL82632 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078949
  ENSRNOP00000085962
GenBank Protein M0R8U1 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000065896   ⟸   ENSRNOT00000074689
RefSeq Acc Id: XP_038959491   ⟸   XM_039103563
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G2L4 (UniProtKB/TrEMBL),   A0A8L2QZ25 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078949   ⟸   ENSRNOT00000101312
Ensembl Acc Id: ENSRNOP00000085962   ⟸   ENSRNOT00000098157
RefSeq Acc Id: NP_001406498   ⟸   NM_001419569
- UniProtKB: A0A8I6A195 (UniProtKB/TrEMBL),   A0A8L2QZ25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137599   ⟸   XM_063281529
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QZ25 (UniProtKB/TrEMBL)
Protein Domains
AAA+ ATPase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560828 AgrOrtholog
BioCyc Gene G2FUF-53908 BioCyc
Ensembl Genes ENSRNOG00000048363 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000098157 ENTREZGENE
  ENSRNOT00000101312 ENTREZGENE
Gene3D-CATH 1.10.287.2620 UniProtKB/Swiss-Prot
  1.10.472.130 UniProtKB/Swiss-Prot
  1.10.8.710 UniProtKB/Swiss-Prot
  1.20.140.100 UniProtKB/Swiss-Prot
  1.20.58.1120 UniProtKB/Swiss-Prot
  1.20.920.20 UniProtKB/Swiss-Prot
  1.20.920.30 UniProtKB/Swiss-Prot
  3.20.180.20 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  AAA_6 UniProtKB/Swiss-Prot
  DHC_fam UniProtKB/Swiss-Prot
  DNAH3_AAA_lid_1 UniProtKB/Swiss-Prot
  DYH2-5-8_CC UniProtKB/Swiss-Prot
  Dynein_2_C UniProtKB/Swiss-Prot
  Dynein_2_N UniProtKB/Swiss-Prot
  Dynein_AAA1S UniProtKB/Swiss-Prot
  Dynein_AAA5_ext UniProtKB/Swiss-Prot
  Dynein_HC_stalk UniProtKB/Swiss-Prot
  Dynein_heavy_chain_D4_dom UniProtKB/Swiss-Prot
  Dynein_heavy_dom-1 UniProtKB/Swiss-Prot
  Dynein_heavy_dom-2 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
NCBI Gene 294854 ENTREZGENE
PANTHER DYNEIN AXONEMAL HEAVY CHAIN 5 UniProtKB/Swiss-Prot
  MALE FERTILITY FACTOR KL5 UniProtKB/Swiss-Prot
Pfam AAA_6 UniProtKB/Swiss-Prot
  AAA_7 UniProtKB/Swiss-Prot
  AAA_8 UniProtKB/Swiss-Prot
  AAA_lid_1 UniProtKB/Swiss-Prot
  DHC_N1 UniProtKB/Swiss-Prot
  DHC_N2 UniProtKB/Swiss-Prot
  DYH2-5-8_CC UniProtKB/Swiss-Prot
  Dynein_AAA_lid UniProtKB/Swiss-Prot
  PF12777 UniProtKB/Swiss-Prot
PhenoGen Dnah5 PhenoGen
RatGTEx ENSRNOG00000048363 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6A195 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G2L4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QZ25 ENTREZGENE
  DYH5_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Dnah5  dynein, axonemal, heavy chain 5  Dnahc5  dynein, axonemal, heavy chain 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dnahc5  dynein, axonemal, heavy chain 5  DLP5  dynein-like prot ein 5  Symbol and Name updated 1299863 APPROVED
2006-02-09 DLP5  dynein-like prot ein 5      Symbol and Name status set to provisional 70820 PROVISIONAL