Map6d1 (MAP6 domain containing 1) - Rat Genome Database

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Gene: Map6d1 (MAP6 domain containing 1) Rattus norvegicus
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Symbol: Map6d1
Name: MAP6 domain containing 1
RGD ID: 1560102
Description: Predicted to enable calmodulin binding activity and microtubule binding activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and regulation of microtubule cytoskeleton organization. Predicted to act upstream of or within negative regulation of microtubule depolymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in Golgi-associated vesicle; cis-Golgi network; and microtubule. Orthologous to human MAP6D1 (MAP6 domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC363823; MAP6 domain-containing protein 1; RGD1560102; similar to hypothetical protein FLJ12748
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,238,552 - 94,244,781 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1194,238,542 - 94,246,901 (+)EnsemblGRCr8
mRatBN7.21180,734,148 - 80,740,377 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,734,148 - 80,740,377 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,453,328 - 89,459,677 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,106,664 - 82,113,013 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,167,807 - 81,174,156 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,321,078 - 84,327,307 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,321,078 - 84,327,307 (+)Ensemblrn6Rnor6.0
Rnor_5.01187,385,908 - 87,392,137 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41182,981,697 - 82,987,926 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,569,527 - 79,575,756 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16837464   PMID:22871113  


Genomics

Comparative Map Data
Map6d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,238,552 - 94,244,781 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1194,238,542 - 94,246,901 (+)EnsemblGRCr8
mRatBN7.21180,734,148 - 80,740,377 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,734,148 - 80,740,377 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1189,453,328 - 89,459,677 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,106,664 - 82,113,013 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01181,167,807 - 81,174,156 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01184,321,078 - 84,327,307 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1184,321,078 - 84,327,307 (+)Ensemblrn6Rnor6.0
Rnor_5.01187,385,908 - 87,392,137 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41182,981,697 - 82,987,926 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1179,569,527 - 79,575,756 (+)NCBICelera
Cytogenetic Map11q23NCBI
MAP6D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383183,815,922 - 183,825,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3183,815,884 - 183,825,594 (-)Ensemblhg38GRCh38
GRCh373183,533,710 - 183,543,365 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,016,364 - 185,026,059 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3181,977,044 - 181,986,772 (-)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3180,943,007 - 180,952,730 (-)NCBIHuRef
CHM1_13183,498,018 - 183,507,719 (-)NCBICHM1_1
T2T-CHM13v2.03186,625,430 - 186,635,070 (-)NCBIT2T-CHM13v2.0
Map6d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,052,059 - 20,060,108 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,052,053 - 20,060,108 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381620,233,309 - 20,241,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,233,303 - 20,241,358 (-)Ensemblmm10GRCm38
MGSCv371620,233,382 - 20,241,431 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361620,148,791 - 20,154,863 (-)NCBIMGSCv36mm8
Celera1620,797,081 - 20,805,013 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.39NCBI
MAP6D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22181,687,890 - 181,697,608 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13181,692,606 - 181,702,324 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03180,851,848 - 180,861,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,019,315 - 189,028,588 (-)NCBIPanPan1.1PanPan1.1panPan2
MAP6D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13416,781,131 - 16,788,432 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3420,873,522 - 20,873,923 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha3420,868,517 - 20,873,468 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03416,693,414 - 16,693,823 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.03416,688,409 - 16,693,360 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.13416,726,662 - 16,731,612 (-)NCBIUMICH_Zoey_3.1
UMICH_Zoey_3.13416,731,666 - 16,732,072 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03416,722,324 - 16,727,271 (-)NCBIUNSW_CanFamBas_1.0
UNSW_CanFamBas_1.03416,727,325 - 16,727,734 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03416,956,945 - 16,957,354 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
UU_Cfam_GSD_1.03416,951,941 - 16,956,891 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Map6d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602119,903,807 - 119,911,309 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365785,995,529 - 6,000,692 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365785,995,629 - 6,003,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP6D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13121,748,648 - 121,755,445 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113121,738,392 - 121,755,482 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,181,186 - 131,190,522 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAP6D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,593,259 - 5,603,781 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,593,327 - 5,601,936 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606314,375,675 - 14,385,812 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map6d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,685,794 - 72,690,561 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473072,683,993 - 72,692,105 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Map6d1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v145,036,200 - 5,042,041 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:67
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000058043
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
RH143813  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21180,734,623 - 80,734,798 (+)MAPPERmRatBN7.2
Rnor_6.01184,321,554 - 84,321,728NCBIRnor6.0
Rnor_5.01187,386,384 - 87,386,558UniSTSRnor5.0
RGSC_v3.41182,982,173 - 82,982,347UniSTSRGSC3.4
Celera1179,570,003 - 79,570,177UniSTS
RH 3.4 Map11668.8UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 11 63 153 69 68 37 34 37 6 224 122 2 139 51 76 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000058043   ⟹   ENSRNOP00000054851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,734,148 - 80,740,377 (+)Ensembl
Rnor_6.0 Ensembl1184,321,078 - 84,327,307 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131134   ⟹   ENSRNOP00000101181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1194,238,542 - 94,246,901 (+)Ensembl
RefSeq Acc Id: NM_001108844   ⟹   NP_001102314
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81194,238,552 - 94,244,781 (+)NCBI
mRatBN7.21180,734,148 - 80,740,377 (+)NCBI
Rnor_6.01184,321,078 - 84,327,307 (+)NCBI
Rnor_5.01187,385,908 - 87,392,137 (+)NCBI
RGSC_v3.41182,981,697 - 82,987,926 (+)RGD
Celera1179,569,527 - 79,575,756 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102314 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77988 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000101181
  ENSRNOP00000101181.1
RefSeq Acc Id: NP_001102314   ⟸   NM_001108844
- UniProtKB: D3ZT16 (UniProtKB/TrEMBL),   A6JSB9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000054851   ⟸   ENSRNOT00000058043
Ensembl Acc Id: ENSRNOP00000101181   ⟸   ENSRNOT00000131134

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZT16-F1-model_v2 AlphaFold D3ZT16 1-191 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698282
Promoter ID:EPDNEW_R8807
Type:single initiation site
Name:Map6d1_1
Description:MAP6 domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01184,321,115 - 84,321,175EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560102 AgrOrtholog
BioCyc Gene G2FUF-20713 BioCyc
Ensembl Genes ENSRNOG00000001911 Ensembl
  ENSRNOG00000090872 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000131134 ENTREZGENE
  ENSRNOT00000131134.1 UniProtKB/TrEMBL
InterPro STOP UniProtKB/TrEMBL
KEGG Report rno:363823 UniProtKB/TrEMBL
NCBI Gene 363823 ENTREZGENE
PANTHER MAP6 DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  STOP UniProtKB/TrEMBL
PhenoGen Map6d1 PhenoGen
RatGTEx ENSRNOG00000001911 RatGTEx
  ENSRNOG00000090872 RatGTEx
UniProt A0ABK0L8G5_RAT UniProtKB/TrEMBL
  A6JSB9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZT16 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Map6d1  MAP6 domain containing 1  RGD1560102_predicted  similar to hypothetical protein FLJ12748 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560102_predicted  similar to hypothetical protein FLJ12748 (predicted)  LOC363823  similar to hypothetical protein FLJ12748  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363823  similar to hypothetical protein FLJ12748      Symbol and Name status set to provisional 70820 PROVISIONAL