Dppa5l1 (developmental pluripotency associated 5 like 1) - Rat Genome Database

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Gene: Dppa5l1 (developmental pluripotency associated 5 like 1) Rattus norvegicus
Analyze
Symbol: Dppa5l1 (Ensembl: RGD1564306)
Name: developmental pluripotency associated 5 like 1 (Ensembl:similar to developmental pluripotency associated 5)
RGD ID: 1559995
Description:
Type: protein-coding
RefSeq Status: MODEL
Previously known as: developmental pluripotency-associated protein 5A-like; LOC299829; RGD1559995; similar to developmental pluripotency associated 5
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,410,419 - 64,411,004 (-)NCBIGRCr8
mRatBN7.2762,525,044 - 62,526,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl762,525,014 - 62,531,945 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl879,215,362 - 79,216,570 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl337,316,133 - 37,316,483 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0769,982,055 - 69,982,644 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl769,982,245 - 69,982,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl338,367,556 - 38,367,903 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,164,006 - 70,164,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4766,740,860 - 66,741,210 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera759,673,229 - 59,673,818 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function
mRNA binding  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Dppa5l1
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:27
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000040010
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system reproductive system
High
Medium
Low 4
Below cutoff 1 7

Sequence


Reference Sequences
RefSeq Acc Id: XM_235194   ⟹   XP_235194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,410,419 - 64,411,004 (-)NCBI
mRatBN7.2762,525,044 - 62,526,042 (-)NCBI
Rnor_6.0769,982,055 - 69,982,644 (-)NCBI
Rnor_5.0770,164,006 - 70,164,590 (-)NCBI
RGSC_v3.4766,740,860 - 66,741,210 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_235194 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000215.3
  ENSRNOP00000038959.5
  ENSRNOP00000041925.4
  ENSRNOP00000071223.2
Reference Protein Sequences
RefSeq Acc Id: XP_235194   ⟸   XM_235194
- UniProtKB: F1LWL9 (UniProtKB/TrEMBL),   F1LVJ7 (UniProtKB/TrEMBL),   F1LXK2 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
KH-like RNA-binding

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559995 AgrOrtholog
BioCyc Gene G2FUF-33808 BioCyc
Ensembl Genes ENSRNOG00000000199 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000029793 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000032335 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000060610 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000215.4 UniProtKB/TrEMBL
  ENSRNOT00000040010.5 UniProtKB/TrEMBL
  ENSRNOT00000049144.5 UniProtKB/TrEMBL
  ENSRNOT00000078193.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
InterPro KH_dom_type_1_sf UniProtKB/TrEMBL
  MOEP19_KH-like UniProtKB/TrEMBL
KEGG Report rno:299829 UniProtKB/TrEMBL
  rno:301101 UniProtKB/TrEMBL
  rno:311031 UniProtKB/TrEMBL
NCBI Gene 299829 ENTREZGENE
PANTHER DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER UniProtKB/TrEMBL
  DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED 5 PROTEIN UniProtKB/TrEMBL
Pfam MOEP19 UniProtKB/TrEMBL
PhenoGen Dppa5l1 PhenoGen
RatGTEx ENSRNOG00000000199 RatGTEx
  ENSRNOG00000029793 RatGTEx
  ENSRNOG00000032335 RatGTEx
  ENSRNOG00000060610 RatGTEx
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt F1LVJ7 ENTREZGENE
  F1LWL9 ENTREZGENE, UniProtKB/TrEMBL
  F1LXK2 ENTREZGENE, UniProtKB/TrEMBL
  F1M487_RAT UniProtKB/TrEMBL
UniProt Secondary F1LVJ7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Dppa5l1  developmental pluripotency associated 5 like 1  RGD1559995  similar to developmental pluripotency associated 5  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1559995  similar to developmental pluripotency associated 5   RGD1559995_predicted  similar to developmental pluripotency associated 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559995_predicted  similar to developmental pluripotency associated 5 (predicted)  LOC299829  similar to developmental pluripotency associated 5  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC299829  similar to developmental pluripotency associated 5      Symbol and Name status set to provisional 70820 PROVISIONAL