Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of MORC4 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Morc4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MORC4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MORC4 mRNA | CTD | PMID:32109520 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Morc4 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of MORC4 mRNA | CTD | PMID:28973697 | acrylamide | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of MORC4 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | MORC4 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of MORC4 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of MORC4 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MORC4 mRNA | CTD | PMID:21934132 | aristolochic acid A | decreases expression | ISO | MORC4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MORC4 mRNA and aristolochic acid I results in decreased expression of MORC4 protein | CTD | PMID:33212167 | arsane | affects methylation | ISO | MORC4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of MORC4 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | MORC4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of MORC4 gene | CTD | PMID:25304211 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of MORC4 mRNA | CTD | PMID:36841081 | benzo[a]pyrene | increases methylation | ISO | MORC4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MORC4 exon | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of MORC4 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | MORC4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MORC4 promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MORC4 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MORC4 mRNA | CTD | PMID:34585602 | carbon nanotube | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of MORC4 mRNA | CTD | PMID:25620056 | choline | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MORC4 mRNA | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of MORC4 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MORC4 mRNA | CTD | PMID:27392435 | copper(II) sulfate | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of MORC4 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MORC4 mRNA | CTD | PMID:20106945 | dicrotophos | decreases expression | ISO | MORC4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MORC4 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MORC4 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | folic acid | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MORC4 mRNA | CTD | PMID:20938992 | hydrogen peroxide | affects expression | ISO | MORC4 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of MORC4 mRNA | CTD | PMID:20044591 | L-methionine | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MORC4 mRNA | CTD | PMID:20938992 | menadione | affects expression | ISO | MORC4 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of MORC4 mRNA | CTD | PMID:20044591 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MORC4 mRNA | CTD | PMID:25729387 | paracetamol | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MORC4 mRNA | CTD | PMID:22230336 and PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of MORC4 mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of MORC4 mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MORC4 mRNA] | CTD | PMID:19482888 | phenylmercury acetate | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of MORC4 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MORC4 mRNA | CTD | PMID:27188386 | PhIP | decreases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of MORC4 mRNA | CTD | PMID:29877212 | pirinixic acid | multiple interactions | ISO | Morc4 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MORC4 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MORC4 mRNA | CTD | PMID:18301758 and PMID:23811191 | pirinixic acid | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MORC4 mRNA | CTD | PMID:19710929 | potassium dichromate | affects expression | ISO | Morc4 (Mus musculus) | 6480464 | Potassium Dichromate affects the expression of MORC4 mRNA | CTD | PMID:23608068 | quercetin | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Quercetin results in increased expression of MORC4 mRNA | CTD | PMID:21632981 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of MORC4 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Silver results in increased expression of MORC4 mRNA | CTD | PMID:28959546 | silver(0) | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Silver results in increased expression of MORC4 mRNA | CTD | PMID:28959546 | sunitinib | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MORC4 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of MORC4 mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | ISO | Morc4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of MORC4 mRNA | CTD | PMID:31919559 | tetraphene | decreases expression | ISO | Morc4 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of MORC4 mRNA | CTD | PMID:26377693 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MORC4 mRNA | CTD | PMID:25729387 | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of MORC4 mRNA | CTD | PMID:25729387 | trimellitic anhydride | decreases expression | ISO | Morc4 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of MORC4 mRNA | CTD | PMID:19042947 | valproic acid | increases methylation | ISO | MORC4 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of MORC4 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | MORC4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MORC4 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | MORC4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MORC4 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | MORC4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MORC4 mRNA | CTD | PMID:19101580 more ... | |