C19h1orf198 (similar to human chromosome 1 open reading frame 198) - Rat Genome Database

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Gene: C19h1orf198 (similar to human chromosome 1 open reading frame 198) Rattus norvegicus
Analyze
Symbol: C19h1orf198
Name: similar to human chromosome 1 open reading frame 198
RGD ID: 1559896
Description: Predicted to be located in cytosol. Orthologous to human C1orf198 (chromosome 1 open reading frame 198); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC498967; LOC498967; RGD1559896; similar to RIKEN cDNA 2310022B05; uncharacterized protein C1orf198 homolog; uncharacterized protein LOC498967
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81969,501,453 - 69,526,826 (-)NCBIGRCr8
mRatBN7.21952,604,060 - 52,629,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1952,604,060 - 52,629,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1959,388,813 - 59,414,196 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01960,240,718 - 60,266,076 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01962,315,271 - 62,340,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01957,396,606 - 57,422,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1957,396,606 - 57,422,093 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01968,101,910 - 68,127,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41954,814,033 - 54,839,538 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1951,973,094 - 51,998,412 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C19h1orf198
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81969,501,453 - 69,526,826 (-)NCBIGRCr8
mRatBN7.21952,604,060 - 52,629,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1952,604,060 - 52,629,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1959,388,813 - 59,414,196 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01960,240,718 - 60,266,076 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01962,315,271 - 62,340,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01957,396,606 - 57,422,124 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1957,396,606 - 57,422,093 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01968,101,910 - 68,127,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41954,814,033 - 54,839,538 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1951,973,094 - 51,998,412 (-)NCBICelera
Cytogenetic Map19q12NCBI
C1orf198
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381230,837,119 - 230,869,591 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1230,837,119 - 230,869,589 (-)EnsemblGRCh38hg38GRCh38
GRCh371230,972,865 - 231,005,337 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361229,039,489 - 229,070,900 (-)NCBINCBI36Build 36hg18NCBI36
Celera1204,238,818 - 204,271,280 (-)NCBICelera
Cytogenetic Map1q42.2NCBI
HuRef1201,457,528 - 201,489,961 (-)NCBIHuRef
CHM1_11232,245,891 - 232,278,311 (-)NCBICHM1_1
T2T-CHM13v2.01230,217,591 - 230,250,079 (-)NCBIT2T-CHM13v2.0
2310022B05Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398125,362,495 - 125,390,108 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8125,362,495 - 125,390,108 (-)EnsemblGRCm39 Ensembl
GRCm388124,635,756 - 124,663,369 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8124,635,756 - 124,663,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv378127,159,656 - 127,187,269 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368127,521,846 - 127,549,459 (-)NCBIMGSCv36mm8
Celera8128,931,821 - 128,961,418 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map872.81NCBI
CUNH1orf198
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554927,762,534 - 7,774,394 (+)NCBIChiLan1.0ChiLan1.0
C1H1orf198
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2118,338,313 - 18,369,450 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,530,872 - 18,561,972 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01206,386,486 - 206,417,583 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11211,413,850 - 211,445,020 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1211,413,850 - 211,445,020 (-)Ensemblpanpan1.1panPan2
C4H1orf198
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.148,531,219 - 8,564,929 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl48,531,001 - 8,564,910 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha48,522,968 - 8,556,697 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.048,555,998 - 8,589,669 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.148,560,088 - 8,593,700 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.048,682,190 - 8,715,818 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.048,912,263 - 8,945,915 (+)NCBIUU_Cfam_GSD_1.0
CUNH1orf198
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934443,466,304 - 43,492,162 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648419,631,524 - 19,657,560 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648419,631,530 - 19,657,388 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C14H1orf198
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1459,515,877 - 59,552,288 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11459,516,754 - 59,553,705 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21464,181,727 - 64,217,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH1orf198
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12568,108,942 - 68,137,870 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2568,106,262 - 68,137,838 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605570,014,494 - 70,045,647 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH1orf198
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477518,739,274 - 18,770,524 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477518,739,501 - 18,770,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C19h1orf198
120 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:274
Count of miRNA genes:178
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000025512
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194997648153225766Rat

Markers in Region
RH128480  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21952,604,147 - 52,604,334 (+)MAPPERmRatBN7.2
Rnor_6.01957,396,694 - 57,396,880NCBIRnor6.0
Rnor_5.01968,101,998 - 68,102,184UniSTSRnor5.0
RGSC_v3.41954,814,121 - 54,814,307UniSTSRGSC3.4
Celera1951,973,182 - 51,973,368UniSTS
RH 3.4 Map19719.8UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 49 33 19 33 1 1 74 35 40 11 1
Low 8 8 8 7 10 1 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000025512   ⟹   ENSRNOP00000025512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1952,604,060 - 52,629,436 (-)Ensembl
Rnor_6.0 Ensembl1957,396,606 - 57,422,093 (-)Ensembl
RefSeq Acc Id: NM_001109134   ⟹   NP_001102604
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81969,501,453 - 69,526,826 (-)NCBI
mRatBN7.21952,604,060 - 52,629,436 (-)NCBI
Rnor_6.01957,396,606 - 57,422,093 (-)NCBI
Rnor_5.01968,101,910 - 68,127,030 (-)NCBI
RGSC_v3.41954,814,033 - 54,839,538 (-)RGD
Celera1951,973,094 - 51,998,412 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772643   ⟹   XP_008770865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81969,501,453 - 69,523,149 (-)NCBI
mRatBN7.21952,604,060 - 52,625,784 (-)NCBI
Rnor_6.01957,396,606 - 57,418,511 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102604 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770865 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96735 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025512
  ENSRNOP00000025512.4
Reference Protein Sequences
RefSeq Acc Id: NP_001102604   ⟸   NM_001109134
- UniProtKB: D3ZY47 (UniProtKB/TrEMBL),   A6KJ13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770865   ⟸   XM_008772643
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000025512   ⟸   ENSRNOT00000025512
Protein Domains
DUF4706

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZY47-F1-model_v2 AlphaFold D3ZY47 1-324 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701236
Promoter ID:EPDNEW_R11760
Type:initiation region
Name:RGD1559896_1
Description:similar to RIKEN cDNA 2310022B05
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01957,422,064 - 57,422,124EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559896 AgrOrtholog
BioCyc Gene G2FUF-5242 BioCyc
Ensembl Genes ENSRNOG00000018836 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025512 ENTREZGENE
  ENSRNOT00000025512.5 UniProtKB/TrEMBL
InterPro DUF4706 UniProtKB/TrEMBL
KEGG Report rno:498967 UniProtKB/TrEMBL
NCBI Gene 498967 ENTREZGENE
PANTHER SIMILAR TO RIKEN CDNA 2310022B05 UniProtKB/TrEMBL
  SIMILAR TO RIKEN CDNA 2310022B05 UniProtKB/TrEMBL
Pfam DUF4706 UniProtKB/TrEMBL
PhenoGen C19h1orf198 PhenoGen
RatGTEx ENSRNOG00000018836 RatGTEx
UniProt A6KJ13 ENTREZGENE, UniProtKB/TrEMBL
  D3ZY47 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-24 C19h1orf198  similar to human chromosome 1 open reading frame 198  RGD1559896  similar to RIKEN cDNA 2310022B05  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1559896  similar to RIKEN cDNA 2310022B05   RGD1559896_predicted  similar to RIKEN cDNA 2310022B05 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559896_predicted  similar to RIKEN cDNA 2310022B05 (predicted)  LOC498967  similar to RIKEN cDNA 2310022B05  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498967  similar to RIKEN cDNA 2310022B05      Symbol and Name status set to provisional 70820 PROVISIONAL