Symbol:
Ilrun
Name:
inflammation and lipid regulator with UBA-like and NBR1-like domains
RGD ID:
1559829
Description:
Predicted to enable ubiquitin binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; negative regulation of defense response to virus; and negative regulation of protein localization to nucleus. Predicted to be located in centrosome; cytosol; and nuclear speck. Predicted to be active in phagophore assembly site. Orthologous to human ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains); INTERACTS WITH gentamycin; thioacetamide; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
chromosome 6 open reading frame 106-like; hypothetical protein LOC294154; LOC294154; LOC294294; MGC124820; RGD1310148; similar to chromosome 6 open reading frame 106 isoform a; similar to hypothetical protein MGC4614; uncharacterized protein C6orf106 homolog; uncharacterized protein LOC294154
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 5,811,721 - 5,878,082 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 20 5,811,734 - 5,877,978 (-) Ensembl GRCr8 mRatBN7.2 20 5,809,931 - 5,876,197 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 5,809,936 - 5,876,012 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 20 6,522,583 - 6,588,605 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 5,884,372 - 5,950,402 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 6,364,082 - 6,430,193 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 20 6,162,848 - 6,229,482 (-) NCBI Dahl_SR_JrHsd Lyon_Normotensive 20 7,158,805 - 7,225,439 (-) NCBI Lyon_Normotensive Lyon_Hypertensive 20 7,161,767 - 7,228,407 (-) NCBI Lyon_Hypertensive F344_StmMcwi 20 6,178,991 - 6,245,091 (-) NCBI F344_StmMcwi Rnor_6.0 20 7,331,321 - 7,397,588 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 7,331,326 - 7,397,448 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 20 9,533,329 - 9,599,034 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 20 5,965,992 - 6,033,724 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 20 7,371,306 - 7,437,251 (-) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Ilrun Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Ilrun (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ilrun Rat 1,2-dimethylhydrazine multiple interactions ISO Ilrun (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ILRUN mRNA CTD PMID:22206623 Ilrun Rat 1,2-dimethylhydrazine increases expression ISO Ilrun (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of ILRUN mRNA CTD PMID:22206623 Ilrun Rat 17beta-estradiol decreases expression ISO ILRUN (Homo sapiens) 6480464 Estradiol results in decreased expression of ILRUN mRNA CTD PMID:16514628 Ilrun Rat 17beta-estradiol decreases expression ISO Ilrun (Mus musculus) 6480464 Estradiol results in decreased expression of ILRUN mRNA CTD PMID:39298647 Ilrun Rat 17beta-estradiol increases expression ISO ILRUN (Homo sapiens) 6480464 Estradiol results in increased expression of ILRUN mRNA CTD PMID:19167446 Ilrun Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ilrun (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ilrun Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ilrun (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ilrun Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Ilrun (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ilrun Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Ilrun (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ILRUN mRNA CTD PMID:26251327 Ilrun Rat 4,4'-sulfonyldiphenol decreases expression ISO Ilrun (Mus musculus) 6480464 bisphenol S results in decreased expression of ILRUN mRNA CTD PMID:39298647 Ilrun Rat 4,4'-sulfonyldiphenol decreases methylation ISO ILRUN (Homo sapiens) 6480464 bisphenol S results in decreased methylation of ILRUN gene CTD PMID:31601247 Ilrun Rat acrylamide increases expression ISO ILRUN (Homo sapiens) 6480464 Acrylamide results in increased expression of ILRUN mRNA CTD PMID:32763439 Ilrun Rat afimoxifene decreases expression ISO ILRUN (Homo sapiens) 6480464 afimoxifene results in decreased expression of ILRUN mRNA CTD PMID:16514628 Ilrun Rat aflatoxin B1 decreases methylation ISO ILRUN (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of ILRUN gene CTD PMID:27153756 Ilrun Rat all-trans-retinoic acid increases expression ISO ILRUN (Homo sapiens) 6480464 Tretinoin results in increased expression of ILRUN mRNA CTD PMID:23724009 Ilrun Rat benzo[a]pyrene increases mutagenesis ISO ILRUN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of ILRUN gene CTD PMID:25435355 Ilrun Rat benzo[a]pyrene multiple interactions ISO Ilrun (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Ilrun Rat benzo[b]fluoranthene multiple interactions ISO Ilrun (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Ilrun Rat bisphenol A increases methylation ISO ILRUN (Homo sapiens) 6480464 bisphenol A results in increased methylation of ILRUN gene CTD PMID:31601247 Ilrun Rat cadmium atom multiple interactions ISO ILRUN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ILRUN more ... CTD PMID:35301059 Ilrun Rat cadmium dichloride increases expression ISO ILRUN (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ILRUN mRNA CTD PMID:38568856 Ilrun Rat cadmium dichloride multiple interactions ISO ILRUN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ILRUN more ... CTD PMID:35301059 Ilrun Rat chrysene multiple interactions ISO Ilrun (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Ilrun Rat cobalt dichloride increases expression ISO ILRUN (Homo sapiens) 6480464 cobaltous chloride results in increased expression of ILRUN mRNA CTD PMID:19320972 Ilrun Rat copper(II) sulfate increases expression ISO ILRUN (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ILRUN mRNA CTD PMID:19549813 Ilrun Rat dimethylarsinous acid increases expression ISO ILRUN (Homo sapiens) 6480464 dimethylarsinous acid results in increased expression of ILRUN mRNA CTD PMID:23487506 Ilrun Rat elemental selenium increases expression ISO ILRUN (Homo sapiens) 6480464 Selenium results in increased expression of ILRUN mRNA CTD PMID:19244175 Ilrun Rat ethanol affects splicing ISO Ilrun (Mus musculus) 6480464 Ethanol affects the splicing of ILRUN mRNA CTD PMID:30319688 Ilrun Rat fenthion decreases expression ISO Ilrun (Mus musculus) 6480464 Fenthion results in decreased expression of ILRUN mRNA CTD PMID:34813904 Ilrun Rat folic acid multiple interactions ISO Ilrun (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ILRUN mRNA CTD PMID:22206623 Ilrun Rat FR900359 decreases phosphorylation ISO ILRUN (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of ILRUN protein CTD PMID:37730182 Ilrun Rat fulvestrant decreases expression ISO ILRUN (Homo sapiens) 6480464 Fulvestrant results in decreased expression of ILRUN mRNA CTD PMID:16514628 Ilrun Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ILRUN mRNA CTD PMID:33387578 Ilrun Rat lithium chloride increases expression ISO ILRUN (Homo sapiens) 6480464 Lithium Chloride results in increased expression of ILRUN mRNA CTD PMID:23527032 Ilrun Rat methidathion decreases expression ISO Ilrun (Mus musculus) 6480464 methidathion results in decreased expression of ILRUN mRNA CTD PMID:34813904 Ilrun Rat nickel sulfate increases expression ISO ILRUN (Homo sapiens) 6480464 nickel sulfate results in increased expression of ILRUN mRNA CTD PMID:22714537 Ilrun Rat paracetamol affects expression ISO Ilrun (Mus musculus) 6480464 Acetaminophen affects the expression of ILRUN mRNA CTD PMID:17562736 Ilrun Rat PCB138 multiple interactions ISO Ilrun (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Ilrun Rat raloxifene decreases expression ISO ILRUN (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased expression of ILRUN mRNA CTD PMID:16514628 Ilrun Rat selenium atom increases expression ISO ILRUN (Homo sapiens) 6480464 Selenium results in increased expression of ILRUN mRNA CTD PMID:19244175 Ilrun Rat sodium arsenite increases expression ISO ILRUN (Homo sapiens) 6480464 sodium arsenite results in increased expression of ILRUN mRNA CTD PMID:38568856 Ilrun Rat tetraphene decreases expression ISO Ilrun (Mus musculus) 6480464 benz(a)anthracene results in decreased expression of ILRUN mRNA CTD PMID:26377693 Ilrun Rat tetraphene multiple interactions ISO Ilrun (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of more ... CTD PMID:27858113 Ilrun Rat thimerosal decreases expression ISO ILRUN (Homo sapiens) 6480464 Thimerosal results in decreased expression of ILRUN mRNA CTD PMID:27188386 Ilrun Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ILRUN mRNA CTD PMID:34492290 Ilrun Rat thiram increases expression ISO ILRUN (Homo sapiens) 6480464 Thiram results in increased expression of ILRUN mRNA CTD PMID:38568856 Ilrun Rat titanium dioxide decreases methylation ISO Ilrun (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ILRUN gene CTD PMID:35295148 Ilrun Rat valproic acid increases expression ISO ILRUN (Homo sapiens) 6480464 Valproic Acid results in increased expression of ILRUN mRNA CTD PMID:28001369|PMID:29154799 Ilrun Rat vorinostat decreases expression ISO ILRUN (Homo sapiens) 6480464 Vorinostat results in decreased expression of ILRUN mRNA CTD PMID:27188386