Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Slc13a4 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of SLC13A4 mRNA | CTD | PMID:30723492 | Slc13a4 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of SLC13A4 mRNA | CTD | PMID:32145629 | Slc13a4 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of SLC13A4 mRNA | CTD | PMID:35192832 | Slc13a4 | Rat | 17beta-estradiol | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Estradiol results in increased expression of SLC13A4 mRNA | CTD | PMID:39298647 | Slc13a4 | Rat | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | 2,5,2',5'-tetrachlorobiphenyl analog results in decreased expression of SLC13A4 mRNA | CTD | PMID:36804509 | Slc13a4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC13A4 mRNA | CTD | PMID:21570461 | Slc13a4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC13A4 mRNA | CTD | PMID:33387578 | Slc13a4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC13A4 mRNA | CTD | PMID:33956508 | Slc13a4 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of SLC13A4 mRNA | CTD | PMID:32109520 | Slc13a4 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC13A4 mRNA | CTD | PMID:30851411 | Slc13a4 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SLC13A4 mRNA | CTD | PMID:30951980 | Slc13a4 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | bisphenol S results in decreased expression of SLC13A4 mRNA | CTD | PMID:30616060 | Slc13a4 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SLC13A4 mRNA | CTD | PMID:28973697 | Slc13a4 | Rat | 6-propyl-2-thiouracil | multiple interactions | ISO | Slc13a4 (Mus musculus) | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC13A4 mRNA | CTD | PMID:36706583 | Slc13a4 | Rat | acrylamide | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of SLC13A4 mRNA | CTD | PMID:35032568 | Slc13a4 | Rat | aflatoxin B1 | increases methylation | ISO | SLC13A4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SLC13A4 gene | CTD | PMID:27153756 | Slc13a4 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SLC13A4 mRNA | CTD | PMID:33354967 | Slc13a4 | Rat | aflatoxin B1 | decreases methylation | ISO | SLC13A4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SLC13A4 intron | CTD | PMID:30157460 | Slc13a4 | Rat | amiodarone | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of SLC13A4 mRNA | CTD | PMID:19774075 | Slc13a4 | Rat | aristolochic acid A | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SLC13A4 mRNA | CTD | PMID:33212167 | Slc13a4 | Rat | arsane | multiple interactions | EXP | | 6480464 | Arsenic inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | arsenic atom | multiple interactions | EXP | | 6480464 | Arsenic inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | SLC13A4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of SLC13A4 gene | CTD | PMID:25435355 | Slc13a4 | Rat | benzo[a]pyrene | affects methylation | ISO | SLC13A4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC13A4 promoter | CTD | PMID:27901495 | Slc13a4 | Rat | benzo[a]pyrene | increases methylation | ISO | SLC13A4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SLC13A4 5' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Slc13a4 | Rat | Benzo[ghi]perylene | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | 1,12-benzoperylene results in decreased expression of SLC13A4 mRNA | CTD | PMID:26377693 | Slc13a4 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of SLC13A4 mRNA | CTD | PMID:31163220 | Slc13a4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC13A4 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:38750585 | Slc13a4 | Rat | bisphenol A | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SLC13A4 mRNA | CTD | PMID:34585602 | Slc13a4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLC13A4 mRNA | CTD | PMID:32145629|PMID:36779543 | Slc13a4 | Rat | bisphenol F | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | bisphenol F results in increased expression of SLC13A4 mRNA | CTD | PMID:30951980 | Slc13a4 | Rat | bisphenol F | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of SLC13A4 mRNA | CTD | PMID:36706583 | Slc13a4 | Rat | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of SLC13A4 mRNA | CTD | PMID:32479839 | Slc13a4 | Rat | cadmium atom | multiple interactions | ISO | Slc13a4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC13A4 more ... | CTD | PMID:37236586 | Slc13a4 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of SLC13A4 mRNA | CTD | PMID:25993096 | Slc13a4 | Rat | cadmium dichloride | multiple interactions | ISO | Slc13a4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC13A4 more ... | CTD | PMID:37236586 | Slc13a4 | Rat | carbon nanotube | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of SLC13A4 mRNA | CTD | PMID:25554681 | Slc13a4 | Rat | chlorpyrifos | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SLC13A4 mRNA | CTD | PMID:37019170 | Slc13a4 | Rat | chromium atom | affects transport | EXP | | 6480464 | SLC13A4 protein affects the transport of Chromium | CTD | PMID:16129486 | Slc13a4 | Rat | chromium atom | multiple interactions | EXP | | 6480464 | Chromium inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of SLC13A4 mRNA | CTD | PMID:24386269 | Slc13a4 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of SLC13A4 mRNA | CTD | PMID:29108742 | Slc13a4 | Rat | dibenz[a,h]anthracene | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | 1,2,5,6-dibenzanthracene results in increased expression of SLC13A4 mRNA | CTD | PMID:26377693 | Slc13a4 | Rat | Dibutyl phosphate | affects expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of SLC13A4 mRNA | CTD | PMID:37042841 | Slc13a4 | Rat | diiodine | multiple interactions | ISO | Slc13a4 (Mus musculus) | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC13A4 mRNA | CTD | PMID:36706583 | Slc13a4 | Rat | dorsomorphin | multiple interactions | ISO | SLC13A4 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Slc13a4 | Rat | Echimidine | increases expression | EXP | | 6480464 | echimidine results in increased expression of SLC13A4 mRNA | CTD | PMID:34185104 | Slc13a4 | Rat | elemental selenium | affects transport | EXP | | 6480464 | SLC13A4 protein affects the transport of Selenium | CTD | PMID:16129486 | Slc13a4 | Rat | elemental selenium | multiple interactions | EXP | | 6480464 | Selenium inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SLC13A4 mRNA | CTD | PMID:29391264 | Slc13a4 | Rat | entinostat | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | entinostat results in increased expression of SLC13A4 mRNA | CTD | PMID:27188386 | Slc13a4 | Rat | ethylparaben | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of SLC13A4 mRNA | CTD | PMID:37690743 | Slc13a4 | Rat | exemestane | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | exemestane results in increased expression of SLC13A4 mRNA | CTD | PMID:17254854 | Slc13a4 | Rat | fluoxetine | decreases expression | EXP | | 6480464 | Fluoxetine results in decreased expression of SLC13A4 mRNA | CTD | PMID:17033635 | Slc13a4 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SLC13A4 mRNA | CTD | PMID:33387578 | Slc13a4 | Rat | Heliotrine | increases expression | EXP | | 6480464 | heliotrine results in increased expression of SLC13A4 mRNA | CTD | PMID:34185104 | Slc13a4 | Rat | Licochalcone B | decreases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of SLC13A4 mRNA | CTD | PMID:33647349 | Slc13a4 | Rat | molybdenum atom | multiple interactions | EXP | | 6480464 | Molybdenum inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | ozone | multiple interactions | ISO | Slc13a4 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:27106289|PMID:34911549 | Slc13a4 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of SLC13A4 mRNA | CTD | PMID:26272509 | Slc13a4 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | SLC13A4 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Slc13a4 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SLC13A4 mRNA | CTD | PMID:32479839|PMID:33387578 | Slc13a4 | Rat | paracetamol | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SLC13A4 mRNA | CTD | PMID:29067470 | Slc13a4 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SLC13A4 mRNA | CTD | PMID:32680482 | Slc13a4 | Rat | phenylmercury acetate | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of SLC13A4 mRNA | CTD | PMID:26272509 | Slc13a4 | Rat | phenylmercury acetate | multiple interactions | ISO | SLC13A4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Slc13a4 | Rat | phosphorus atom | multiple interactions | EXP | | 6480464 | Phosphorus inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | phosphorus(.) | multiple interactions | EXP | | 6480464 | Phosphorus inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | pirinixic acid | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of SLC13A4 mRNA | CTD | PMID:23811191 | Slc13a4 | Rat | potassium dichromate | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of SLC13A4 mRNA | CTD | PMID:23608068 | Slc13a4 | Rat | rac-lactic acid | decreases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC13A4 mRNA | CTD | PMID:30851411 | Slc13a4 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of SLC13A4 mRNA | CTD | PMID:28374803 | Slc13a4 | Rat | SB 431542 | multiple interactions | ISO | SLC13A4 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Slc13a4 | Rat | selenium atom | affects transport | EXP | | 6480464 | SLC13A4 protein affects the transport of Selenium | CTD | PMID:16129486 | Slc13a4 | Rat | selenium atom | multiple interactions | EXP | | 6480464 | Selenium inhibits the reaction [SLC13A4 protein affects the transport of Sulfates] | CTD | PMID:16129486 | Slc13a4 | Rat | Senkirkine | increases expression | EXP | | 6480464 | senkirkine results in increased expression of SLC13A4 mRNA | CTD | PMID:34185104 | Slc13a4 | Rat | sodium arsenite | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SLC13A4 mRNA | CTD | PMID:36209798 | Slc13a4 | Rat | sodium atom | multiple interactions | EXP | | 6480464 | SLC13A4 protein affects the transport of [Sulfates co-treated with Sodium] | CTD | PMID:16129486 | Slc13a4 | Rat | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of SLC13A4 mRNA | CTD | PMID:25993096 | Slc13a4 | Rat | sulfates | multiple interactions | EXP | | 6480464 | Arsenic inhibits the reaction [SLC13A4 protein affects the transport of Sulfates]; Chromium inhibits the reaction more ... | CTD | PMID:16129486 | Slc13a4 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SLC13A4 mRNA | CTD | PMID:30723492 | Slc13a4 | Rat | thalidomide | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Thalidomide results in decreased expression of SLC13A4 mRNA | CTD | PMID:26217789 | Slc13a4 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLC13A4 mRNA | CTD | PMID:23411599|PMID:34492290 | Slc13a4 | Rat | titanium dioxide | decreases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SLC13A4 mRNA | CTD | PMID:23557971 | Slc13a4 | Rat | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of SLC13A4 mRNA | CTD | PMID:30589522 | Slc13a4 | Rat | valproic acid | affects expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SLC13A4 mRNA | CTD | PMID:25979313 | Slc13a4 | Rat | valproic acid | increases expression | ISO | SLC13A4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC13A4 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:26272509|PMID:27188386 | Slc13a4 | Rat | valproic acid | multiple interactions | ISO | SLC13A4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Slc13a4 | Rat | vancomycin | increases expression | ISO | Slc13a4 (Mus musculus) | 6480464 | Vancomycin results in increased expression of SLC13A4 mRNA | CTD | PMID:18930951 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















