SLC13A4 (solute carrier family 13 member 4) - Rat Genome Database

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Gene: SLC13A4 (solute carrier family 13 member 4) Sus scrofa
Analyze
Symbol: SLC13A4
Name: solute carrier family 13 member 4
RGD ID: 13898943
Description: ENCODES a protein that exhibits sodium:sulfate symporter activity (ortholog); INVOLVED IN sodium ion transmembrane transport (inferred); sodium ion transport (inferred); transmembrane transport (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); liver cirrhosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH ammonia
Type: protein-coding
RefSeq Status: MODEL
Previously known as: solute carrier family 13 (sodium/sulfate symporters), member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1813,593,756 - 13,636,180 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11813,593,735 - 13,641,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21814,326,517 - 14,368,472 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ammonia  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC13A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1813,593,756 - 13,636,180 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11813,593,735 - 13,641,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21814,326,517 - 14,368,472 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC13A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387135,681,231 - 135,728,186 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7135,681,231 - 135,729,258 (-)EnsemblGRCh38hg38GRCh38
GRCh377135,365,979 - 135,412,934 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367135,016,525 - 135,063,473 (-)NCBINCBI36Build 36hg18NCBI36
Build 347134,823,243 - 134,870,188NCBI
Celera7130,103,444 - 130,150,391 (-)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7129,668,796 - 129,716,167 (-)NCBIHuRef
CHM1_17135,299,894 - 135,346,826 (-)NCBICHM1_1
T2T-CHM13v2.07136,988,529 - 137,035,495 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27134,710,411 - 134,757,363 (-)NCBI
Slc13a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39635,244,888 - 35,285,061 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl635,244,892 - 35,285,066 (-)EnsemblGRCm39 Ensembl
GRCm38635,267,953 - 35,308,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl635,267,957 - 35,308,131 (-)EnsemblGRCm38mm10GRCm38
MGSCv37635,217,953 - 35,258,126 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36635,198,110 - 35,238,278 (-)NCBIMGSCv36mm8
Celera635,268,639 - 35,308,823 (-)NCBICelera
Cytogenetic Map6B1NCBI
cM Map615.26NCBI
Slc13a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,910,505 - 64,955,986 (-)NCBIGRCr8
mRatBN7.2463,943,369 - 63,988,852 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,943,395 - 63,988,857 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx468,902,588 - 68,939,998 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0464,818,212 - 64,855,622 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0463,220,720 - 63,258,128 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0462,796,732 - 62,841,053 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl462,797,677 - 62,840,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0462,519,667 - 62,563,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4462,679,593 - 62,724,547 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,955,724 - 63,000,677 (-)NCBI
Celera458,992,508 - 59,035,406 (-)NCBICelera
Cytogenetic Map4q22NCBI
Slc13a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554947,014,252 - 7,055,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554947,013,577 - 7,057,767 (+)NCBIChiLan1.0ChiLan1.0
SLC13A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26172,507,573 - 172,555,237 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1724,516,316 - 24,564,967 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07127,653,170 - 127,700,080 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17140,150,963 - 140,197,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7140,150,963 - 140,197,418 (-)Ensemblpanpan1.1panPan2
SLC13A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11612,539,369 - 12,581,155 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1612,540,263 - 12,579,949 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1613,552,201 - 13,592,905 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01612,519,168 - 12,559,926 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1612,519,260 - 12,559,921 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11612,961,771 - 13,002,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01612,061,603 - 12,102,305 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01612,200,417 - 12,241,091 (+)NCBIUU_Cfam_GSD_1.0
Slc13a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511818,722,716 - 18,769,513 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936592454,191 - 497,090 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936592450,237 - 497,050 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC13A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121104,359,577 - 104,407,905 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21104,363,792 - 104,405,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660721,253,811 - 1,300,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc13a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476515,963,047 - 16,000,929 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476515,960,269 - 16,001,700 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC13A4
1774 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017995   ⟹   ENSSSCP00000017511
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1813,593,756 - 13,636,180 (+)Ensembl
RefSeq Acc Id: XM_003134643   ⟹   XP_003134691
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11813,593,735 - 13,641,649 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003134691 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000017511
  ENSSSCP00000017511.5
  ENSSSCP00005017770.1
  ENSSSCP00015045219.1
  ENSSSCP00025020388.1
  ENSSSCP00035004539.1
  ENSSSCP00065003490.1
  ENSSSCP00070043315.1
Reference Protein Sequences
RefSeq Acc Id: XP_003134691   ⟸   XM_003134643
- UniProtKB: F1SNI6 (UniProtKB/TrEMBL),   A0A8D0YMJ0 (UniProtKB/TrEMBL),   A0A480EGU6 (UniProtKB/TrEMBL),   A0A4X1VIN1 (UniProtKB/TrEMBL),   A0A8D0UEG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000017511   ⟸   ENSSSCT00000017995


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016527 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005018303 UniProtKB/TrEMBL
  ENSSSCG00015079049 UniProtKB/TrEMBL
  ENSSSCG00025034867 UniProtKB/TrEMBL
  ENSSSCG00035010760 UniProtKB/TrEMBL
  ENSSSCG00065006140 UniProtKB/TrEMBL
  ENSSSCG00070025614 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017995 ENTREZGENE
  ENSSSCT00000017995.5 UniProtKB/TrEMBL
  ENSSSCT00005029116.1 UniProtKB/TrEMBL
  ENSSSCT00015107165.1 UniProtKB/TrEMBL
  ENSSSCT00025047591.1 UniProtKB/TrEMBL
  ENSSSCT00035013449.1 UniProtKB/TrEMBL
  ENSSSCT00065008262.1 UniProtKB/TrEMBL
  ENSSSCT00070051213.1 UniProtKB/TrEMBL
InterPro SLC13A/DASS UniProtKB/TrEMBL
KEGG Report ssc:100522048 UniProtKB/TrEMBL
NCBI Gene SLC13A4 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 13 MEMBER UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 13 MEMBER 4 UniProtKB/TrEMBL
Pfam Na_sulph_symp UniProtKB/TrEMBL
UniProt A0A480EGU6 ENTREZGENE
  A0A4X1VIN1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0UEG5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YMJ0 ENTREZGENE
  F1SNI6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480EGU6 UniProtKB/TrEMBL
  A0A8D0YMJ0 UniProtKB/TrEMBL
VGNC ID VGNC:92931 ENTREZGENE