Plcz1 (phospholipase C, zeta 1) - Rat Genome Database

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Gene: Plcz1 (phospholipase C, zeta 1) Rattus norvegicus
Analyze
Symbol: Plcz1
Name: phospholipase C, zeta 1
RGD ID: 1359567
Description: Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Involved in positive regulation of cytosolic calcium ion concentration involved in egg activation. Located in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 17. Orthologous to human PLCZ1 (phospholipase C zeta 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1; phosphoinositide phospholipase C-zeta-1; phospholipase C-zeta-1; PLC-zeta-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,604,281 - 174,660,368 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4174,604,281 - 174,660,290 (-)EnsemblGRCr8
mRatBN7.24172,873,110 - 172,929,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4179,168,219 - 179,223,363 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,952,394 - 175,007,537 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,572,940 - 173,628,084 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)Ensemblrn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4161,424,191 - 161,480,156 (-)NCBICelera
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Cytogenetic Map4q44NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
perinuclear region of cytoplasm  (IEA)
pronucleus  (IDA,ISO)
sperm head  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish. Ito M, etal., Biol Reprod. 2008 Jun;78(6):1081-90. doi: 10.1095/biolreprod.108.067801. Epub 2008 Mar 5.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12117804   PMID:14701816   PMID:26116451   PMID:26721930   PMID:28270562  


Genomics

Comparative Map Data
Plcz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,604,281 - 174,660,368 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4174,604,281 - 174,660,290 (-)EnsemblGRCr8
mRatBN7.24172,873,110 - 172,929,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4179,168,219 - 179,223,363 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,952,394 - 175,007,537 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,572,940 - 173,628,084 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)Ensemblrn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4161,424,191 - 161,480,156 (-)NCBICelera
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Cytogenetic Map4q44NCBI
PLCZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,645,609 - 18,738,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,683,169 - 18,738,100 (-)Ensemblhg38GRCh38
GRCh371218,836,114 - 18,890,946 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,727,383 - 18,782,185 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341218,727,382 - 18,782,185NCBI
Celera1223,981,631 - 24,036,436 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1218,604,503 - 18,659,985 (-)NCBIHuRef
CHM1_11218,801,167 - 18,856,044 (-)NCBICHM1_1
T2T-CHM13v2.01218,521,542 - 18,613,927 (-)NCBIT2T-CHM13v2.0
Plcz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396139,933,118 - 139,987,188 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6139,935,399 - 139,987,183 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386139,987,396 - 140,041,488 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6139,989,673 - 140,041,457 (-)Ensemblmm10GRCm38
MGSCv376139,938,243 - 139,989,938 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366139,952,128 - 140,003,823 (-)NCBIMGSCv36mm8
Celera6143,053,490 - 143,105,163 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map669.77NCBI
Plcz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541314,791,703 - 14,845,792 (-)Ensembl
ChiLan1.0NW_00495541314,791,750 - 14,846,327 (-)NCBIChiLan1.0ChiLan1.0
PLCZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21024,085,594 - 24,175,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,082,355 - 24,172,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01218,678,349 - 18,733,048 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,064,945 - 19,119,559 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1219,028,011 - 19,119,559 (-)EnsemblpanPan2panpan1.1
PLCZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12728,363,207 - 28,446,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2728,362,999 - 28,419,270 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2718,005,284 - 18,088,033 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02728,694,850 - 28,777,322 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2728,695,423 - 28,750,192 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12728,541,596 - 28,624,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02728,534,157 - 28,616,711 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02717,713,109 - 17,795,922 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plcz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494589,598,377 - 89,650,717 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365487,522,926 - 7,573,540 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365487,522,902 - 7,573,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl554,408,296 - 54,452,417 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1554,257,709 - 54,452,557 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2557,680,677 - 57,724,905 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11118,534,672 - 18,587,756 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1118,534,734 - 18,586,041 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606916,626,501 - 16,679,788 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475219,803,995 - 19,879,605 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475219,726,686 - 19,883,279 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Plcz1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v169,521,627 - 9,575,968 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plcz1
159 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000011376
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 5 4 69 18 22 5 8 5 6 53 28 10 52 10 65 17 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY885259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011376   ⟹   ENSRNOP00000011376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4174,604,281 - 174,660,290 (-)Ensembl
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)Ensembl
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)Ensembl
RefSeq Acc Id: NM_001012234   ⟹   NP_001012234
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,290 (-)NCBI
mRatBN7.24172,873,114 - 172,929,117 (-)NCBI
Rnor_6.04174,125,178 - 174,180,729 (-)NCBI
Rnor_5.04238,378,233 - 238,434,471 (-)NCBI
RGSC_v3.44177,096,157 - 177,162,109 (-)RGD
Celera4161,424,191 - 161,480,156 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237600   ⟹   XP_006237662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,327 (-)NCBI
mRatBN7.24172,873,110 - 172,929,145 (-)NCBI
Rnor_6.04174,125,072 - 174,181,519 (-)NCBI
Rnor_5.04238,378,233 - 238,434,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592771   ⟹   XP_017448260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,522 (-)NCBI
Rnor_6.04174,125,072 - 174,179,856 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108046   ⟹   XP_038963974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,524 (-)NCBI
RefSeq Acc Id: XM_039108047   ⟹   XP_038963975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,327 (-)NCBI
mRatBN7.24172,873,110 - 172,929,145 (-)NCBI
RefSeq Acc Id: XM_039108048   ⟹   XP_038963976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,350 (-)NCBI
mRatBN7.24172,873,110 - 172,929,162 (-)NCBI
RefSeq Acc Id: XM_039108050   ⟹   XP_038963978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,345 (-)NCBI
mRatBN7.24172,873,110 - 172,929,164 (-)NCBI
RefSeq Acc Id: XM_039108051   ⟹   XP_038963979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,524 (-)NCBI
RefSeq Acc Id: XM_039108052   ⟹   XP_038963980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,631,850 (-)NCBI
mRatBN7.24172,873,110 - 172,900,685 (-)NCBI
RefSeq Acc Id: XM_063286453   ⟹   XP_063142523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,367 (-)NCBI
RefSeq Acc Id: XM_063286454   ⟹   XP_063142524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,353 (-)NCBI
RefSeq Acc Id: XM_063286455   ⟹   XP_063142525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,306 (-)NCBI
RefSeq Acc Id: XM_063286456   ⟹   XP_063142526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,351 (-)NCBI
RefSeq Acc Id: XR_010065686
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,607,533 - 174,660,368 (-)NCBI
RefSeq Acc Id: NP_001012234   ⟸   NM_001012234
- UniProtKB: Q5FX52 (UniProtKB/Swiss-Prot),   A6IMM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237662   ⟸   XM_006237600
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448260   ⟸   XM_017592771
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000011376   ⟸   ENSRNOT00000011376
RefSeq Acc Id: XP_038963978   ⟸   XM_039108050
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963976   ⟸   XM_039108048
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963975   ⟸   XM_039108047
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963979   ⟸   XM_039108051
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963974   ⟸   XM_039108046
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963980   ⟸   XM_039108052
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063142523   ⟸   XM_063286453
- Peptide Label: isoform X1
- UniProtKB: Q5FX52 (UniProtKB/Swiss-Prot),   A6IMM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142524   ⟸   XM_063286454
- Peptide Label: isoform X1
- UniProtKB: Q5FX52 (UniProtKB/Swiss-Prot),   A6IMM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142526   ⟸   XM_063286456
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142525   ⟸   XM_063286455
- Peptide Label: isoform X3
Protein Domains
C2   EF-hand   PI-PLC X-box   PI-PLC Y-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FX52-F1-model_v2 AlphaFold Q5FX52 1-645 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359567 AgrOrtholog
BioCyc Gene G2FUF-42543 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000008514 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011376 ENTREZGENE
  ENSRNOT00000011376.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
  3.20.20.190 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  PI-PLC_fam UniProtKB/Swiss-Prot
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot
  PLC_EF-hand-like UniProtKB/Swiss-Prot
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot
KEGG Report rno:497197 UniProtKB/Swiss-Prot
NCBI Gene 497197 ENTREZGENE
PANTHER PTHR10336 UniProtKB/Swiss-Prot
  PTHR10336:SF29 UniProtKB/Swiss-Prot
Pfam EF-hand_like UniProtKB/Swiss-Prot
  PF00168 UniProtKB/Swiss-Prot
  PI-PLC-X UniProtKB/Swiss-Prot
  PI-PLC-Y UniProtKB/Swiss-Prot
PhenoGen Plcz1 PhenoGen
PRINTS PHPHLIPASEC UniProtKB/Swiss-Prot
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
  PIPLC_X_DOMAIN UniProtKB/Swiss-Prot
  PIPLC_Y_DOMAIN UniProtKB/Swiss-Prot
  PS50004 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008514 RatGTEx
SMART PLCXc UniProtKB/Swiss-Prot
  PLCYc UniProtKB/Swiss-Prot
  SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
  SSF49562 UniProtKB/Swiss-Prot
  SSF51695 UniProtKB/Swiss-Prot
UniProt A6IMM6 ENTREZGENE, UniProtKB/TrEMBL
  PLCZ1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-29 Plcz1  phospholipase C, zeta 1      Symbol and Name status set to provisional 70820 PROVISIONAL