PLCZ1 (phospholipase C zeta 1) - Rat Genome Database

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Gene: PLCZ1 (phospholipase C zeta 1) Pan paniscus
Analyze
Symbol: PLCZ1
Name: phospholipase C zeta 1
RGD ID: 11893311
Description: ENCODES a protein that exhibits calcium ion binding (inferred); hydrolase activity (inferred); phosphatidylinositol phospholipase C activity (inferred); INVOLVED IN calcium ion transport (ortholog); egg activation (ortholog); ASSOCIATED WITH genetic disease (ortholog); spermatogenic failure 17 (ortholog); FOUND IN cytoplasm (ortholog); pronucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21024,085,594 - 24,175,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,082,355 - 24,172,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01218,678,349 - 18,733,048 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,064,945 - 19,119,559 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1219,028,011 - 19,119,559 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLCZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21024,085,594 - 24,175,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,082,355 - 24,172,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01218,678,349 - 18,733,048 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,064,945 - 19,119,559 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1219,028,011 - 19,119,559 (-)Ensemblpanpan1.1panPan2
PLCZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,645,609 - 18,738,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,683,169 - 18,738,100 (-)EnsemblGRCh38hg38GRCh38
GRCh371218,836,114 - 18,890,946 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,727,383 - 18,782,185 (-)NCBINCBI36Build 36hg18NCBI36
Build 341218,727,382 - 18,782,185NCBI
Celera1223,981,631 - 24,036,436 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1218,604,503 - 18,659,985 (-)NCBIHuRef
CHM1_11218,801,167 - 18,856,044 (-)NCBICHM1_1
T2T-CHM13v2.01218,521,542 - 18,613,927 (-)NCBIT2T-CHM13v2.0
Plcz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396139,933,118 - 139,987,188 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6139,935,399 - 139,987,183 (-)EnsemblGRCm39 Ensembl
GRCm386139,987,396 - 140,041,488 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6139,989,673 - 140,041,457 (-)EnsemblGRCm38mm10GRCm38
MGSCv376139,938,243 - 139,989,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366139,952,128 - 140,003,823 (-)NCBIMGSCv36mm8
Celera6143,053,490 - 143,105,163 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map669.77NCBI
Plcz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,604,281 - 174,660,368 (-)NCBIGRCr8
mRatBN7.24172,873,110 - 172,929,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4179,168,219 - 179,223,363 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,952,394 - 175,007,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,572,940 - 173,628,084 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Celera4161,424,191 - 161,480,156 (-)NCBICelera
Cytogenetic Map4q44NCBI
Plcz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541314,791,703 - 14,845,792 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541314,791,750 - 14,846,327 (-)NCBIChiLan1.0ChiLan1.0
PLCZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12728,363,207 - 28,446,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2728,362,999 - 28,419,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2718,005,284 - 18,088,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02728,694,850 - 28,777,322 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2728,695,423 - 28,750,192 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12728,541,596 - 28,624,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02728,534,157 - 28,616,711 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02717,713,109 - 17,795,922 (-)NCBIUU_Cfam_GSD_1.0
Plcz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494589,598,377 - 89,650,717 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365487,522,926 - 7,573,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365487,522,902 - 7,573,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl554,408,296 - 54,452,417 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1554,257,709 - 54,452,557 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2557,680,677 - 57,724,905 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11118,534,672 - 18,587,756 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1118,534,734 - 18,586,041 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606916,626,501 - 16,679,788 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475219,803,995 - 19,879,605 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475219,726,686 - 19,883,279 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000042878   ⟹   ENSPPAP00000020092
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1219,028,011 - 19,119,015 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042891   ⟹   ENSPPAP00000020105
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1219,028,011 - 19,119,015 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042913   ⟹   ENSPPAP00000020127
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1219,064,945 - 19,119,559 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042918   ⟹   ENSPPAP00000020132
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1219,065,004 - 19,118,878 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042921   ⟹   ENSPPAP00000020135
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1219,069,678 - 19,117,846 (-)Ensembl
RefSeq Acc Id: XM_055095442   ⟹   XP_054951417
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21024,114,010 - 24,175,572 (-)NCBI
NHGRI_mPanPan11224,110,771 - 24,172,333 (-)NCBI
RefSeq Acc Id: XM_057299392   ⟹   XP_057155375
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21024,122,676 - 24,175,573 (-)NCBI
NHGRI_mPanPan11224,119,437 - 24,172,334 (-)NCBI
RefSeq Acc Id: XM_057299393   ⟹   XP_057155376
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21024,122,676 - 24,162,777 (-)NCBI
NHGRI_mPanPan11224,119,437 - 24,159,538 (-)NCBI
RefSeq Acc Id: XR_008620383
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21024,085,594 - 24,162,776 (-)NCBI
NHGRI_mPanPan11224,082,355 - 24,159,537 (-)NCBI
RefSeq Acc Id: XR_008620384
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21024,085,718 - 24,168,508 (-)NCBI
NHGRI_mPanPan11224,082,479 - 24,165,269 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000020127   ⟸   ENSPPAT00000042913
RefSeq Acc Id: ENSPPAP00000020132   ⟸   ENSPPAT00000042918
RefSeq Acc Id: ENSPPAP00000020135   ⟸   ENSPPAT00000042921
RefSeq Acc Id: ENSPPAP00000020092   ⟸   ENSPPAT00000042878
RefSeq Acc Id: ENSPPAP00000020105   ⟸   ENSPPAT00000042891
RefSeq Acc Id: XP_054951417   ⟸   XM_055095442
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ARV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155375   ⟸   XM_057299392
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ARV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057155376   ⟸   XM_057299393
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AWC2 (UniProtKB/TrEMBL)
Protein Domains
C2   EF-hand   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033231 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042878.1 UniProtKB/TrEMBL
  ENSPPAT00000042891.1 UniProtKB/TrEMBL
  ENSPPAT00000042913.1 UniProtKB/TrEMBL
  ENSPPAT00000042918.1 UniProtKB/TrEMBL
  ENSPPAT00000042921.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene PLCZ1 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF29 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt A0A2R9ARV7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ARZ2_PANPA UniProtKB/TrEMBL
  A0A2R9ARZ6_PANPA UniProtKB/TrEMBL
  A0A2R9AWC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AWF5_PANPA UniProtKB/TrEMBL