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Gene: Trim10 (tripartite motif-containing 10) Rattus norvegicus

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Symbol:

Trim10

Name:

tripartite motif-containing 10

RGD ID:

1359438

Description:

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in host-mediated suppression of symbiont invasion. Predicted to act upstream of or within erythrocyte differentiation. Predicted to be active in cytoplasm. Orthologous to human TRIM10 (tripartite motif containing 10); INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Rfb30; Rnf9; tripartite motif protein 10; tripartite motif-containing protein 10

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIM10 (tripartite motif containing 10)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Trim10 (tripartite motif-containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Trim10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIM10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIM10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Trim10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIM10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIM10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Trim10 (tripartite motif containing 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	COX8A (cytochrome c oxidase subunit 8A)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TRIM10 (tripartite motif containing 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Trim10 (tripartite motif-containing 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	trim47 (tripartite motif containing 47)	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Danio rerio (zebrafish):	btr01 (bloodthirsty-related gene family, member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Danio rerio (zebrafish):	btr12 (bloodthirsty-related gene family, member 12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Danio rerio (zebrafish):	btr09 (bloodthirsty-related gene family, member 9)	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Caenorhabditis elegans (roundworm):	F43C11.7	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Caenorhabditis elegans (roundworm):	Y47G6A.14	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nhl-3	Alliance	DIOPT (Ensembl Compara\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C28G1.6	Alliance	DIOPT (Ensembl Compara\|InParanoid)
Xenopus tropicalis (tropical clawed frog):	XB5796700	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	XB5960628	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408243	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC100490328	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493468	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408231	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408245	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408247	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493962	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC108644876	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408362	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC101731211	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC100494464	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC100489535	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408358	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408232	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408362	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC105945670	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408360	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Xenopus tropicalis (tropical clawed frog):	LOC116408361	Alliance	DIOPT (Ensembl Compara\|Hieranoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	1,694,771 - 1,703,724 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	1,694,779 - 1,703,469 (-)	Ensembl				GRCr8
mRatBN7.2	20	1,689,554 - 1,698,948 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	1,689,562 - 1,698,252 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	1,742,890 - 1,751,637 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	1,746,384 - 1,755,137 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	1,686,933 - 1,695,661 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	2,182,945 - 2,191,640 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	2,182,941 - 2,191,640 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	4,219,702 - 4,228,396 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	1,781,869 - 1,790,921 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	2,398,517 - 2,406,997 (-)	NCBI		Celera
RGSC_v3.1	20	1,781,952 - 1,790,843 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

irritant dermatitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-butoxyethanol (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium dichloride (EXP)

CGP 52608 (ISO)

chlorotoluron (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

endosulfan (EXP)

ethanol (ISO)

fulvestrant (ISO)

nickel atom (ISO)

paracetamol (ISO)

sodium hydroxide (ISO)

thioacetamide (EXP)

Tributyltin oxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

tungsten (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

erythrocyte differentiation (ISO)

host-mediated suppression of symbiont invasion (IEA,ISO)

innate immune response (IBA,IEA,ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IBA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells.	Harada H, etal., Mol Cell Biol 1999 May;19(5):3808-15.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:11331580	PMID:12477932	PMID:18248090	PMID:31472958	PMID:32343488

Genomics

Comparative Map Data

Trim10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	1,694,771 - 1,703,724 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	1,694,779 - 1,703,469 (-)	Ensembl				GRCr8
mRatBN7.2	20	1,689,554 - 1,698,948 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	1,689,562 - 1,698,252 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	1,742,890 - 1,751,637 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	1,746,384 - 1,755,137 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	1,686,933 - 1,695,661 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	2,182,945 - 2,191,640 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	2,182,941 - 2,191,640 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	4,219,702 - 4,228,396 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	1,781,869 - 1,790,921 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	2,398,517 - 2,406,997 (-)	NCBI		Celera
RGSC_v3.1	20	1,781,952 - 1,790,843 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

TRIM10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	30,151,943 - 30,164,009 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	30,151,943 - 30,161,211 (-)	Ensembl			hg38	GRCh38
GRCh37	6	30,119,720 - 30,128,988 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	30,227,701 - 30,236,690 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	30,227,704 - 30,236,690	NCBI
Celera	6	31,717,991 - 31,726,978 (-)	NCBI		Celera
Cytogenetic Map	6	p22.1	NCBI
HuRef	6	29,917,897 - 29,926,885 (-)	NCBI		HuRef
CHM1_1	6	30,121,797 - 30,130,784 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	30,016,218 - 30,028,317 (-)	NCBI		T2T-CHM13v2.0

Trim10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	37,180,388 - 37,188,725 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	37,180,466 - 37,188,725 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	36,869,496 - 36,877,833 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	36,869,574 - 36,877,833 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	37,006,519 - 37,014,778 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	36,477,645 - 36,485,873 (+)	NCBI		MGSCv36	mm8
Celera	17	40,288,815 - 40,297,080 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	19.16	NCBI

Trim10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955583	269,266 - 276,675 (-)	Ensembl
ChiLan1.0	NW_004955583	268,856 - 277,079 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIM10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	44,745,137 - 44,765,147 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	40,708,125 - 40,728,151 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	29,929,516 - 29,938,355 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	30,599,782 - 30,608,158 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	30,601,812 - 30,608,082 (-)	Ensembl			panPan2	panpan1.1

TRIM10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	26,349,624 - 26,357,002 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	26,350,125 - 26,356,592 (-)	Ensembl			canFam3	CanFam3.1

Trim10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	32,701,050 - 32,709,593 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936723	883,009 - 890,310 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936723	882,960 - 890,740 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	22,718,000 - 22,731,491 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	22,718,000 - 22,731,445 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	24,844,769 - 24,857,770 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	42,345,957 - 42,355,537 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	42,346,657 - 42,353,512 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	29,803,220 - 29,810,831 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim10
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	9,839,955 - 9,847,812 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Trim10
39 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	35
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000001016
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2306850	Pia40	Pristane induced arthritis QTL 40		0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1533200	5306452	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	1	6693431	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26128279	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	6693431	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
724519	Bp144	Blood pressure QTL 144		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	20	1	3629303	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

D20Yum4

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	1,696,732 - 1,696,938 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	2,190,121 - 2,190,326	NCBI	Rnor6.0
Rnor_5.0	20	4,226,877 - 4,227,082	UniSTS	Rnor5.0
RGSC_v3.4	20	1,789,402 - 1,789,607	UniSTS	RGSC3.4
Celera	20	2,405,478 - 2,405,683	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	8	61	141	81	80	52	86	52	6	309	178	11	118	58	84	28	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001009176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039098474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX883051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001016 ⟹ ENSRNOP00000001016

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	1,694,779 - 1,703,469 (-)	Ensembl
mRatBN7.2 Ensembl	20	1,689,562 - 1,698,252 (-)	Ensembl
Rnor_6.0 Ensembl	20	2,182,941 - 2,191,640 (-)	Ensembl

RefSeq Acc Id:

NM_001009176 ⟹ NP_001009176

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,694,775 - 1,703,469 (-)	NCBI
mRatBN7.2	20	1,689,558 - 1,698,252 (-)	NCBI
Rnor_6.0	20	2,182,945 - 2,191,640 (-)	NCBI
Rnor_5.0	20	4,219,702 - 4,228,396 (-)	NCBI
RGSC_v3.4	20	1,781,869 - 1,790,921 (-)	RGD
Celera	20	2,398,517 - 2,406,997 (-)	RGD

Sequence:

show sequence

AAAGGAAAGATCTCTTTCAACAGTGGACTGCAGAGAGAATACACACTTATTTTTATGTTTTTTT
TCCTGTGAGCAGCTTCGGGTAGACAGAAAGAGACAGTGAGACCCAGGCCATAGGAACTGGTCCG
GAGAGTGAACTTATGATGCTGTGAGCTCCTGGGCCCTCCTCCTCTGCTATTTCTACATCTCCGC
TGTTGGCAGGAGTGTGTCTGCTCCCAGGAGAGTCGAACAAGGGGTTCTGGTGCCAGAGATGTAA
CTGGGCCCCTTGTCCGAGTGTGTGTGACTGTACTAGTGTTCAGGACTGACGTGGATGAGAGATG
GTGACTTCCAGGAGTCAGAAGGCCCAGTAGGGTTGACATGGCCTCAGCTCCTTCCGTGACTAGC
CTGGCAGATGAGGTCAACTGCCCCATCTGCCAAGGCACCCTAAGGGAACCAGTCACCATTGACT
GTGGCCACAATTTCTGTCGTGGCTGCCTCACTCGCTTCTGTGAGACCCCAGGCCCAGAATCGGA
AGAGTCCCTCAGCTGCCCGCTCTGCAAAGAGCCCTTCCGTCCAGGGAGCTTCCGGCCAAACTGG
CAGCTGGCCAATGTGGTGGAGAATATCGAGCGCCTTCAGCTGGCATCCACAAGAGGCCTGGAGG
TGGAGGATGCCTGTCCGGAACACGGGGAGAAAATCTACTTCTTCTGCGAGGAGGATGAGGCACA
GTTGTGTGTGGTATGCCGCGAGACTGGACAGCATGGGGCTCACACTGTGCGCTTCCTGGAGGAC
GCAGCAGGTCCCTACAGGGAACAAATACAGAAGTGTCTCGTGTGTCTAAGGAAAGAGAGAGAGG
AGATTCAGGAAACCCAATCAAGAGAAAACAAAAGAATACAAGTGCTCCTGACGCAGGTAGCCAC
CAAGAAGCAACAGGTGATTTCACAGTTTGCTCATCTGAGCCGGTTCCTGGAGCGACAGCAGACT
GTGCTCTTGGCACAGCTGGAGGGGTTGGACGGGGACATCCTGAAGCAGCAGGAAGAGTTTGATT
CCCTGGCCACGAGGGAGATCTGCCGGTTCAGCACCCTGATCGAGGAGCTGGAGGAGAAGAATGA
GCGGCCAGCCAGGGGGCTCCTGACGGATATCAGAAGCACTCTAATAAGATGTGAAACCAGAAAG
GGCCGGAAACCTGAGGCTATATCCCCAGGACTGGGCCAAAGGATCCGGGACTTCCCCCAACAGG
TCATGCCCCTGCGGCAGGAGATGAAGATATTTCTGGAAAAACTCTGCTTTGAGTTGGACTATGA
GCCAGCTCTTATCTCTCTAGACCCCCAGACTTCCCACCCCAAGCTCCTCCTCTCTGAAGACCAT
CGGAAGGCTCAGTTCTCCTACAAATGGCAGAATTCACCAGATACTCCACAACGCTTTGATCGAG
CCACCTGCGTTCTGGCCCGATGTGGCTTTACAGAGGGGAGACACACTTGGGTGGTGAATGTCGA
CTTGGCCCACGGAGGCAGCTGCACTATAGGTGTGGTCAAAGAAGATGTACGAAGAAAGGGAGAA
GTGAGGCTGAGGCCAGAGGAGGGAATATGGGCAGTGAGGCTGGCTTGGGGCTTTGTCTCAGCTC
TGGGTTCCTTCCCCACAAGGCTAGCCCTGGAGGAGCAACCCCGGAAGGTGCAGGTGTCTCTTGA
CTATGAGGTAGGCTGGGTGACCTTTGTCAATGCTGACACCCAAGAACATATCTATACCTTCACT
GCCTTCTTCACGCAGAAGGTCTTTCCCTTTTTTGGACTCTGGGGCAGAGGGTCCAGTTTTTCCC
TGAGCTGTCAGGAAGGTGTAGTTTCCCTCCTCTGAGTACAAGACTGGAATCAAGCACCCTTGGG
AGCAGACCCTTGGCTGGGTCTCCAGGCTCAAACGTGAATTTTTTAGATAGTTGGGATGGCATGT
GTTAGTAAGGGACAAGGTAGTAGGACCTTTAGTTTCTTCATTGTTCAAGCCTTTCCCCAGTGTC
CATCAGATGCTCAGGGTGTCTGGGACCTTGGCTGCTGCAGGCTGGTCTCACCACTGTCATCAAC
GGGCACAGACATGGATGTACAAACAGTGCTGGCTTTTAAGCCTAAAGACCTGGATTCCAGATGA
AGCCCTGTCATCACCCAGCTGCGTGATTTTAAACAAAACTTTGCCTCTTCATTCTGTTTTCTTC
CAAAGATATTAGCTAATTTATTCATATTTCAAGAAACATTTGGAGGCATAGATGTGATCAAAAC
ACACACACACACACATACGCACACACATACACACACACACCATATATATATATATATGTATTAT
ATAAAGGATAAATAAAAATGTTGTTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039098472 ⟹ XP_038954400

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,694,771 - 1,703,581 (-)	NCBI
mRatBN7.2	20	1,689,554 - 1,698,354 (-)	NCBI

RefSeq Acc Id:

XM_039098473 ⟹ XP_038954401

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,697,592 - 1,703,724 (-)	NCBI
mRatBN7.2	20	1,692,375 - 1,698,430 (-)	NCBI

RefSeq Acc Id:

XM_039098474 ⟹ XP_038954402

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,695,687 - 1,703,724 (-)	NCBI
mRatBN7.2	20	1,690,472 - 1,698,948 (-)	NCBI

RefSeq Acc Id:

XM_063278992 ⟹ XP_063135062

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,694,771 - 1,703,635 (-)	NCBI

RefSeq Acc Id:

XM_063278993 ⟹ XP_063135063

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,694,771 - 1,703,591 (-)	NCBI

RefSeq Acc Id:

XM_063278994 ⟹ XP_063135064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	1,697,592 - 1,703,724 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001009176	(Get FASTA)	NCBI Sequence Viewer
	XP_038954400	(Get FASTA)	NCBI Sequence Viewer
	XP_038954401	(Get FASTA)	NCBI Sequence Viewer
	XP_038954402	(Get FASTA)	NCBI Sequence Viewer
	XP_063135062	(Get FASTA)	NCBI Sequence Viewer
	XP_063135063	(Get FASTA)	NCBI Sequence Viewer
	XP_063135064	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI29079	(Get FASTA)	NCBI Sequence Viewer
	CAE84058	(Get FASTA)	NCBI Sequence Viewer
	EDL84604	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001016
	ENSRNOP00000001016.5

RefSeq Acc Id:

NP_001009176 ⟸ NM_001009176

- UniProtKB:

Q6MFY9 (UniProtKB/TrEMBL), A1L1I7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASAPSVTSLADEVNCPICQGTLREPVTIDCGHNFCRGCLTRFCETPGPESEESLSCPLCKEPF
RPGSFRPNWQLANVVENIERLQLASTRGLEVEDACPEHGEKIYFFCEEDEAQLCVVCRETGQHG
AHTVRFLEDAAGPYREQIQKCLVCLRKEREEIQETQSRENKRIQVLLTQVATKKQQVISQFAHL
SRFLERQQTVLLAQLEGLDGDILKQQEEFDSLATREICRFSTLIEELEEKNERPARGLLTDIRS
TLIRCETRKGRKPEAISPGLGQRIRDFPQQVMPLRQEMKIFLEKLCFELDYEPALISLDPQTSH
PKLLLSEDHRKAQFSYKWQNSPDTPQRFDRATCVLARCGFTEGRHTWVVNVDLAHGGSCTIGVV
KEDVRRKGEVRLRPEEGIWAVRLAWGFVSALGSFPTRLALEEQPRKVQVSLDYEVGWVTFVNAD
TQEHIYTFTAFFTQKVFPFFGLWGRGSSFSLSCQEGVVSLL

hide sequence

Ensembl Acc Id:

ENSRNOP00000001016 ⟸ ENSRNOT00000001016

RefSeq Acc Id:	XP_038954400 ⟸ XM_039098472
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038954402 ⟸ XM_039098474
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038954401 ⟸ XM_039098473
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063135062 ⟸ XM_063278992
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063135063 ⟸ XM_063278993
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063135064 ⟸ XM_063278994
- Peptide Label:	isoform X4

Protein Domains

B box-type B30.2/SPRY RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6MFY9-F1-model_v2	AlphaFold	Q6MFY9	1-489	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359438	AgrOrtholog
BioCyc Gene	G2FUF-4969	BioCyc
Ensembl Genes	ENSRNOG00000000782	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001016	ENTREZGENE
	ENSRNOT00000001016.9	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8371876	IMAGE-MGC_LOAD
InterPro	B30.2/SPRY_sf	UniProtKB/TrEMBL
	B302	UniProtKB/TrEMBL
	Butyrophylin	UniProtKB/TrEMBL
	ConA-like_dom	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	SPRY_rcpt	UniProtKB/TrEMBL
	TRIM/RBCC	UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	rno:294210	UniProtKB/TrEMBL
MGC_CLONE	MGC:156534	IMAGE-MGC_LOAD
NCBI Gene	294210	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE TRIM	UniProtKB/TrEMBL
Pfam	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
	zf-B_box	UniProtKB/TrEMBL
	zf-C3HC4_4	UniProtKB/TrEMBL
PhenoGen	Trim10	PhenoGen
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000782	RatGTEx
SMART	BBOX	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/TrEMBL
	ConA_like_lec_gl	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
UniProt	A1L1I7	ENTREZGENE, UniProtKB/TrEMBL
	Q6MFY9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-31	Trim10	tripartite motif-containing 10	Trim10	tripartite motif protein 10	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Trim10	tripartite motif protein 10		tripartite motif-containing 10	Name updated	1299863	APPROVED
2005-12-06	Trim10	tripartite motif-containing 10			Symbol and Name updated	1559027	APPROVED
2005-07-29	Trim10	tripartite motif-containing 10			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD