Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Prrt1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of PRRT1 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Prrt1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA] | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRRT1 mRNA | CTD | PMID:22808131 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PRRT1 mRNA | CTD | PMID:27913140 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Prrt1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PRRT1 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PRRT1 mRNA | CTD | PMID:24780913 and PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of PRRT1 mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PRRT1 mRNA | CTD | PMID:33167477 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PRRT1 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PRRT1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRRT1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PRRT1 gene | CTD | PMID:25304211 | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of PRRT1 mRNA | CTD | PMID:36841081 | benzo[a]pyrene | increases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PRRT1 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | affects methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PRRT1 3' UTR | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PRRT1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | ISO | Prrt1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PRRT1 mRNA | CTD | PMID:38074096 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PRRT1 mRNA | CTD | PMID:36041667 | buta-1,3-diene | decreases expression | ISO | Prrt1 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of PRRT1 mRNA | CTD | PMID:29038090 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of PRRT1 promoter | CTD | PMID:22457795 | chlorpyrifos | increases expression | ISO | Prrt1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of PRRT1 mRNA | CTD | PMID:37019170 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of PRRT1 mRNA | CTD | PMID:20187946 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of PRRT1 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of PRRT1 mRNA | CTD | PMID:26033743 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of PRRT1 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | PRRT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | entinostat results in increased expression of PRRT1 mRNA | CTD | PMID:27188386 | ethanol | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of PRRT1 mRNA | CTD | PMID:30319688 | ethylparaben | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of PRRT1 mRNA | CTD | PMID:37690743 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of PRRT1 mRNA | CTD | PMID:30307764 | folic acid | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of PRRT1 mRNA] | CTD | PMID:22206623 | folic acid | increases expression | ISO | Prrt1 (Mus musculus) | 6480464 | Folic Acid results in increased expression of PRRT1 mRNA | CTD | PMID:25629700 | folic acid | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of PRRT1 mRNA | CTD | PMID:21867686 | fonofos | increases methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of PRRT1 promoter | CTD | PMID:22847954 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of PRRT1 mRNA | CTD | PMID:27387713 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of PRRT1 mRNA | CTD | PMID:22061828 and PMID:33387578 | iron dichloride | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of PRRT1 mRNA | CTD | PMID:35984750 | lead diacetate | affects expression | EXP | | 6480464 | lead acetate affects the expression of PRRT1 protein | CTD | PMID:36539177 | lead(0) | affects expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Lead affects the expression of PRRT1 mRNA | CTD | PMID:28903495 | maneb | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of PRRT1 mRNA | CTD | PMID:36117858 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PRRT1 mRNA | CTD | PMID:30047161 | O-methyleugenol | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of PRRT1 mRNA | CTD | PMID:32234424 | paracetamol | affects expression | ISO | Prrt1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PRRT1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PRRT1 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | ISO | Prrt1 (Mus musculus) | 6480464 | Paraquat results in decreased expression of PRRT1 mRNA | CTD | PMID:22563483 | paraquat | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of PRRT1 mRNA | CTD | PMID:36117858 | parathion | increases methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | Parathion results in increased methylation of PRRT1 promoter | CTD | PMID:22847954 | pirinixic acid | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PRRT1 mRNA | CTD | PMID:19710929 | quercetin | increases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of PRRT1 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | PRRT1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of PRRT1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | PRRT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | Prrt1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PRRT1 mRNA | CTD | PMID:37682722 | succimer | multiple interactions | ISO | Prrt1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of PRRT1 mRNA | CTD | PMID:21641980 | terbufos | increases methylation | ISO | PRRT1 (Homo sapiens) | 6480464 | terbufos results in increased methylation of PRRT1 promoter | CTD | PMID:22847954 | testosterone | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PRRT1 mRNA | CTD | PMID:33359661 | thimerosal | decreases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of PRRT1 mRNA | CTD | PMID:27188386 | triptonide | increases expression | ISO | Prrt1 (Mus musculus) | 6480464 | triptonide results in increased expression of PRRT1 mRNA | CTD | PMID:33045310 | tris(2-butoxyethyl) phosphate | affects expression | ISO | PRRT1 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PRRT1 mRNA | CTD | PMID:29024780 | valproic acid | increases expression | ISO | PRRT1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PRRT1 mRNA | CTD | PMID:23179753 | valproic acid | multiple interactions | ISO | PRRT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRRT1 mRNA | CTD | PMID:27188386 | |