Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mapre3 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MAPRE3 mRNA | CTD | PMID:22079256 | Mapre3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAPRE3 mRNA | CTD | PMID:36331819 | Mapre3 | Rat | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1,2-Dimethylhydrazine results in increased expression of MAPRE3 mRNA | CTD | PMID:27840820 | Mapre3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MAPRE3 mRNA | CTD | PMID:22206623 | Mapre3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MAPRE3 mRNA | CTD | PMID:18796159 | Mapre3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression more ... | CTD | PMID:25975270 | Mapre3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MAPRE3 mRNA | CTD | PMID:21296121 | Mapre3 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of MAPRE3 mRNA | CTD | PMID:21346803 | Mapre3 | Rat | 2-methylcholine | affects expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of MAPRE3 mRNA | CTD | PMID:21179406 | Mapre3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MAPRE3 mRNA | CTD | PMID:20188158 | Mapre3 | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of MAPRE3 protein | CTD | PMID:26072098 | Mapre3 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of MAPRE3 mRNA | CTD | PMID:18648102 | Mapre3 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | Mapre3 (Mus musculus) | 6480464 | bisphenol S affects the expression of MAPRE3 mRNA | CTD | PMID:39298647 | Mapre3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of MAPRE3 protein | CTD | PMID:34186270 | Mapre3 | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [Decitabine affects the methylation of MAPRE3 gene] which affects the expression of MAPRE3 mRNA | CTD | PMID:18559491 | Mapre3 | Rat | all-trans-retinoic acid | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Tretinoin results in increased expression of MAPRE3 mRNA | CTD | PMID:16604517 | Mapre3 | Rat | antimycin A | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of MAPRE3 mRNA | CTD | PMID:33512557 | Mapre3 | Rat | aristolochic acid A | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of MAPRE3 mRNA | CTD | PMID:33212167 | Mapre3 | Rat | arsane | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | arsenic atom | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | arsenite(3-) | increases methylation | ISO | MAPRE3 (Homo sapiens) | 6480464 | arsenite results in increased methylation of MAPRE3 promoter | CTD | PMID:23974009 | Mapre3 | Rat | arsenite(3-) | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | arsenite results in increased expression of MAPRE3 protein | CTD | PMID:37955338 | Mapre3 | Rat | azoxystrobin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of MAPRE3 mRNA | CTD | PMID:33512557 | Mapre3 | Rat | benzo[a]pyrene | affects methylation | ISO | MAPRE3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MAPRE3 5' UTR | CTD | PMID:27901495 | Mapre3 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MAPRE3 mRNA | CTD | PMID:25181051 | Mapre3 | Rat | bisphenol A | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of MAPRE3 protein | CTD | PMID:34186270 | Mapre3 | Rat | bisphenol A | increases methylation | ISO | MAPRE3 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of MAPRE3 gene | CTD | PMID:31601247 | Mapre3 | Rat | bisphenol A | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of MAPRE3 gene | CTD | PMID:31601247 | Mapre3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in decreased methylation of MAPRE3 gene | CTD | PMID:28505145 | Mapre3 | Rat | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of MAPRE3 gene | CTD | PMID:28505145 | Mapre3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MAPRE3 gene | CTD | PMID:28505145 | Mapre3 | Rat | Bisphenol B | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of MAPRE3 protein | CTD | PMID:34186270 | Mapre3 | Rat | bisphenol F | decreases expression | ISO | Mapre3 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of MAPRE3 mRNA | CTD | PMID:38685157 | Mapre3 | Rat | bisphenol F | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of MAPRE3 protein | CTD | PMID:34186270 | Mapre3 | Rat | Butylbenzyl phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | carbon nanotube | decreases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of MAPRE3 mRNA | CTD | PMID:25554681 | Mapre3 | Rat | CGP 52608 | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MAPRE3 gene] | CTD | PMID:28238834 | Mapre3 | Rat | chlorpyrifos | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MAPRE3 mRNA | CTD | PMID:37019170 | Mapre3 | Rat | chromium(6+) | affects expression | ISO | Mapre3 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of MAPRE3 mRNA | CTD | PMID:28472532 | Mapre3 | Rat | cisplatin | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MAPRE3 mRNA | CTD | PMID:27392435 | Mapre3 | Rat | copper atom | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [Thiosemicarbazones binds to Copper] which results in increased expression of MAPRE3 protein | CTD | PMID:20931265 | Mapre3 | Rat | copper(0) | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [Thiosemicarbazones binds to Copper] which results in increased expression of MAPRE3 protein | CTD | PMID:20931265 | Mapre3 | Rat | cyclosporin A | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MAPRE3 mRNA | CTD | PMID:20106945 | Mapre3 | Rat | DDE | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of MAPRE3 mRNA | CTD | PMID:38568856 | Mapre3 | Rat | deguelin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | deguelin results in decreased expression of MAPRE3 mRNA | CTD | PMID:33512557 | Mapre3 | Rat | Dibutyl phosphate | affects expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MAPRE3 mRNA | CTD | PMID:37042841 | Mapre3 | Rat | dibutyl phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | dichloroacetic acid | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of MAPRE3 mRNA | CTD | PMID:28962523 | Mapre3 | Rat | diethyl phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | diisobutyl phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | diisononyl phthalate | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Mapre3 | Rat | diquat | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | Diquat results in increased expression of MAPRE3 mRNA | CTD | PMID:36851058 | Mapre3 | Rat | doxorubicin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MAPRE3 mRNA | CTD | PMID:29803840 | Mapre3 | Rat | folic acid | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of MAPRE3 mRNA | CTD | PMID:21867686 | Mapre3 | Rat | folic acid | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MAPRE3 mRNA | CTD | PMID:22206623 | Mapre3 | Rat | FR900359 | increases phosphorylation | ISO | MAPRE3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of MAPRE3 protein | CTD | PMID:37730182 | Mapre3 | Rat | fulvestrant | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of MAPRE3 gene | CTD | PMID:31601247 | Mapre3 | Rat | genistein | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in decreased methylation of MAPRE3 gene | CTD | PMID:28505145 | Mapre3 | Rat | ivermectin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MAPRE3 protein | CTD | PMID:32959892 | Mapre3 | Rat | manganese atom | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | manganese(0) | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | manganese(II) chloride | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | N(4)-hydroxycytidine | decreases expression | ISO | Mapre3 (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of MAPRE3 mRNA | CTD | PMID:37748715 | Mapre3 | Rat | okadaic acid | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of MAPRE3 mRNA | CTD | PMID:38832940 | Mapre3 | Rat | olesoxime | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | olesoxime inhibits the reaction [Paclitaxel results in decreased localization of MAPRE3 protein]; olesoxime inhibits the more ... | CTD | PMID:20417191 | Mapre3 | Rat | paclitaxel | affects localization | ISO | MAPRE3 (Homo sapiens) | 6480464 | Paclitaxel affects the localization of MAPRE3 protein | CTD | PMID:20417191 | Mapre3 | Rat | paclitaxel | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | olesoxime inhibits the reaction [Paclitaxel results in decreased localization of MAPRE3 protein] | CTD | PMID:20417191 | Mapre3 | Rat | paracetamol | affects expression | ISO | Mapre3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MAPRE3 mRNA | CTD | PMID:17562736 | Mapre3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MAPRE3 mRNA | CTD | PMID:33387578 | Mapre3 | Rat | paracetamol | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MAPRE3 mRNA | CTD | PMID:22230336 | Mapre3 | Rat | perfluorononanoic acid | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of MAPRE3 mRNA | CTD | PMID:32588087 | Mapre3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MAPRE3 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Mapre3 | Rat | permethrin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Permethrin results in decreased expression of MAPRE3 mRNA | CTD | PMID:37047231 | Mapre3 | Rat | phenobarbital | affects expression | ISO | Mapre3 (Mus musculus) | 6480464 | Phenobarbital affects the expression of MAPRE3 mRNA | CTD | PMID:23091169 | Mapre3 | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of MAPRE3 mRNA | CTD | PMID:20345932 | Mapre3 | Rat | picoxystrobin | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of MAPRE3 mRNA | CTD | PMID:33512557 | Mapre3 | Rat | pirinixic acid | multiple interactions | ISO | Mapre3 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Mapre3 | Rat | pirinixic acid | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MAPRE3 mRNA | CTD | PMID:17426115|PMID:18301758 | Mapre3 | Rat | potassium chromate | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of MAPRE3 mRNA | CTD | PMID:22079256 | Mapre3 | Rat | potassium chromate | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of MAPRE3 mRNA | CTD | PMID:22079256 | Mapre3 | Rat | pyrimidifen | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | pyrimidifen results in decreased expression of MAPRE3 mRNA | CTD | PMID:33512557 | Mapre3 | Rat | rifampicin | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Rifampin results in increased expression of MAPRE3 mRNA | CTD | PMID:24552687 | Mapre3 | Rat | sodium arsenate | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of MAPRE3 mRNA | CTD | PMID:39847705 | Mapre3 | Rat | sodium arsenite | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Mapre3 | Rat | sulforaphane | increases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of MAPRE3 mRNA | CTD | PMID:26833863 | Mapre3 | Rat | temozolomide | decreases expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of MAPRE3 mRNA | CTD | PMID:31758290 | Mapre3 | Rat | tert-butyl hydroperoxide | increases expression | ISO | Mapre3 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in increased expression of MAPRE3 mRNA | CTD | PMID:15003993 | Mapre3 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of MAPRE3 mRNA | CTD | PMID:23411599|PMID:34492290 | Mapre3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of MAPRE3 mRNA | CTD | PMID:33387578 | Mapre3 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of MAPRE3 mRNA | CTD | PMID:30589522 | Mapre3 | Rat | triphenyl phosphate | affects expression | ISO | MAPRE3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MAPRE3 mRNA | CTD | PMID:37042841 | Mapre3 | Rat | vincristine | multiple interactions | ISO | MAPRE3 (Homo sapiens) | 6480464 | olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE3 protein] | CTD | PMID:20417191 | Mapre3 | Rat | vincristine | affects localization | ISO | MAPRE3 (Homo sapiens) | 6480464 | Vincristine affects the localization of MAPRE3 protein | CTD | PMID:20417191 | | |||||||||||||||||||||||||||||||||||||||||||||||||






















