Or6b3 (olfactory receptor family 6 subfamily B member 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or6b3 (olfactory receptor family 6 subfamily B member 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6b3
Name: olfactory receptor family 6 subfamily B member 3
RGD ID: 1334141
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6B2 (olfactory receptor family 6 subfamily B member 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1345; olfactory receptor gene Olr1345; olfactory receptor Olr1345; Olr1345
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89100,517,492 - 100,518,430 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9100,517,492 - 100,518,430 (-)EnsemblGRCr8
mRatBN7.2993,070,031 - 93,070,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,067,048 - 93,077,530 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9101,506,044 - 101,506,982 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09106,641,808 - 106,642,746 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09104,997,713 - 104,998,651 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0999,680,041 - 99,680,979 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl999,680,041 - 99,680,979 (-)Ensemblrn6Rnor6.0
Rnor_5.0999,345,155 - 99,346,093 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4991,717,881 - 91,718,819 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera990,608,657 - 90,609,595 (-)NCBICelera
RGSC_v3.1991,922,649 - 91,923,588 (-)NCBI
Cytogenetic Map9q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or6b3
5 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:117
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000049347
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
6 1 4 5 5 5 8

Sequence


Ensembl Acc Id: ENSRNOT00000049347   ⟹   ENSRNOP00000044358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl999,680,041 - 99,680,979 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104409   ⟹   ENSRNOP00000089841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl993,067,085 - 93,075,923 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112744   ⟹   ENSRNOP00000078191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl993,067,048 - 93,073,756 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115635   ⟹   ENSRNOP00000079783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl993,067,048 - 93,077,530 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116808   ⟹   ENSRNOP00000087296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl993,067,234 - 93,075,071 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000131149   ⟹   ENSRNOP00000100354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9100,517,492 - 100,518,430 (-)Ensembl
RefSeq Acc Id: NM_001000753   ⟹   NP_001000753
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89100,517,492 - 100,518,430 (-)NCBI
mRatBN7.2993,070,031 - 93,070,969 (-)NCBI
Rnor_6.0999,680,041 - 99,680,979 (-)NCBI
Rnor_5.0999,345,155 - 99,346,093 (-)NCBI
RGSC_v3.4991,717,881 - 91,718,819 (-)RGD
Celera990,608,657 - 90,609,595 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000753 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91991 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000100354
  ENSRNOP00000100354.1
RefSeq Acc Id: NP_001000753   ⟸   NM_001000753
- UniProtKB: D3ZTU1 (UniProtKB/TrEMBL),   A6JQU6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000044358   ⟸   ENSRNOT00000049347
Ensembl Acc Id: ENSRNOP00000087296   ⟸   ENSRNOT00000116808
Ensembl Acc Id: ENSRNOP00000089841   ⟸   ENSRNOT00000104409
Ensembl Acc Id: ENSRNOP00000079783   ⟸   ENSRNOT00000115635
Ensembl Acc Id: ENSRNOP00000078191   ⟸   ENSRNOT00000112744
Ensembl Acc Id: ENSRNOP00000100354   ⟸   ENSRNOT00000131149
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTU1-F1-model_v2 AlphaFold D3ZTU1 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334141 AgrOrtholog
BioCyc Gene G2FUF-26687 BioCyc
Ensembl Genes ENSRNOG00000047633 Ensembl
  ENSRNOG00000064010 Ensembl
  ENSRNOG00000086068 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000131149 ENTREZGENE
  ENSRNOT00000131149.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR UniProtKB/TrEMBL
KEGG Report rno:405023 UniProtKB/TrEMBL
NCBI Gene 405023 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6b3 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047633 RatGTEx
  ENSRNOG00000064010 RatGTEx
  ENSRNOG00000086068 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6JQU6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZTU1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6b3  olfactory receptor family 6 subfamily B member 3  Olr1345  olfactory receptor 1345  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1345  olfactory receptor 1345   Olr1345_predicted  olfactory receptor 1345 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1345_predicted  olfactory receptor 1345 (predicted)      Symbol and Name status set to approved 70820 APPROVED