OR6B3 (olfactory receptor family 6 subfamily B member 3) - Rat Genome Database

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Gene: OR6B3 (olfactory receptor family 6 subfamily B member 3) Homo sapiens
Analyze
Symbol: OR6B3
Name: olfactory receptor family 6 subfamily B member 3
RGD ID: 1350028
HGNC Page HGNC:15042
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Located in cytosol and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: olfactory receptor 6B3; olfactory receptor OR2-2; olfactory receptor, family 6, subfamily B, member 3 pseudogene; OR6B3P; OR6B3Q
RGD Orthologs
Mouse
Rat
Bonobo
Pig
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,044,571 - 240,053,521 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,044,571 - 240,053,521 (-)EnsemblGRCh38hg38GRCh38
GRCh372240,983,988 - 240,992,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,633,167 - 240,634,162 (-)NCBINCBI36Build 36hg18NCBI36
Build 342240,704,483 - 240,705,479NCBI
Celera2234,657,516 - 234,658,511 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2232,742,367 - 232,743,362 (-)NCBIHuRef
CHM1_12240,990,010 - 240,991,005 (-)NCBICHM1_1
T2T-CHM13v2.02240,537,284 - 240,546,234 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IDA)
membrane  (IEA)
plasma membrane  (IDA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14983052   PMID:21244100   PMID:21873635   PMID:23602568   PMID:29348145  


Genomics

Comparative Map Data
OR6B3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,044,571 - 240,053,521 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,044,571 - 240,053,521 (-)EnsemblGRCh38hg38GRCh38
GRCh372240,983,988 - 240,992,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,633,167 - 240,634,162 (-)NCBINCBI36Build 36hg18NCBI36
Build 342240,704,483 - 240,705,479NCBI
Celera2234,657,516 - 234,658,511 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2232,742,367 - 232,743,362 (-)NCBIHuRef
CHM1_12240,990,010 - 240,991,005 (-)NCBICHM1_1
T2T-CHM13v2.02240,537,284 - 240,546,234 (-)NCBIT2T-CHM13v2.0
Or6b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39192,438,770 - 92,446,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl192,434,088 - 92,446,383 (-)EnsemblGRCm39 Ensembl
GRCm38192,511,048 - 92,518,515 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl192,506,366 - 92,518,661 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,407,625 - 94,415,092 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,341,494 - 94,342,432 (-)NCBIMGSCv36mm8
Celera195,451,733 - 95,459,206 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.45NCBI
Or6b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89100,495,938 - 100,496,876 (-)NCBIGRCr8
mRatBN7.2993,048,475 - 93,049,413 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,045,014 - 93,053,641 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9101,484,533 - 101,485,471 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09106,620,297 - 106,621,235 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09104,976,153 - 104,977,091 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0999,656,296 - 99,659,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl999,658,487 - 99,659,425 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0999,323,601 - 99,324,539 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,696,327 - 91,697,265 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1991,901,095 - 91,902,034 (-)NCBI
Celera990,587,098 - 90,588,036 (-)NCBICelera
Cytogenetic Map9q36NCBI
LOC100968789
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213142,694,264 - 142,703,270 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B142,709,230 - 142,718,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B127,289,492 - 127,290,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,105,172 - 246,106,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,105,172 - 246,106,170 (-)Ensemblpanpan1.1panPan2
LOC100625810
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115139,049,403 - 139,050,341 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215154,082,948 - 154,083,886 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in OR6B3
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q37.1-37.3(chr2:231770279-242126245)x1 copy number loss See cases [RCV000050304] Chr2:231770279..242126245 [GRCh38]
Chr2:232634989..243059659 [GRCh37]
Chr2:232343233..242717069 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:236555233-242126245)x1 copy number loss See cases [RCV000051120] Chr2:236555233..242126245 [GRCh38]
Chr2:237463876..243059659 [GRCh37]
Chr2:237128615..242717069 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237643996-242126245)x1 copy number loss See cases [RCV000051133] Chr2:237643996..242126245 [GRCh38]
Chr2:238552639..243059659 [GRCh37]
Chr2:238217378..242717069 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:234345842-242126245)x1 copy number loss See cases [RCV000051163] Chr2:234345842..242126245 [GRCh38]
Chr2:235254486..243059659 [GRCh37]
Chr2:234919225..242717069 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235741079-242032456)x1 copy number loss See cases [RCV000052673] Chr2:235741079..242032456 [GRCh38]
Chr2:236649723..242974607 [GRCh37]
Chr2:236314462..242623280 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:236775572-242065349)x1 copy number loss See cases [RCV000052674] Chr2:236775572..242065349 [GRCh38]
Chr2:237684215..243007500 [GRCh37]
Chr2:237348954..242656173 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237526184-241996090)x1 copy number loss See cases [RCV000052675] Chr2:237526184..241996090 [GRCh38]
Chr2:238434827..242938241 [GRCh37]
Chr2:238099566..242586914 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237643996-242065208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052700]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052700]|See cases [RCV000052700] Chr2:237643996..242065208 [GRCh38]
Chr2:238552639..243007359 [GRCh37]
Chr2:238217378..242656032 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:238939181-242065208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052701]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052701]|See cases [RCV000052701] Chr2:238939181..242065208 [GRCh38]
Chr2:239860877..243007359 [GRCh37]
Chr2:239525814..242656032 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:234172536-242086301)x1 copy number loss See cases [RCV000052669] Chr2:234172536..242086301 [GRCh38]
Chr2:235081180..243028452 [GRCh37]
Chr2:234745919..242677125 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:234668159-242126245)x1 copy number loss See cases [RCV000052670] Chr2:234668159..242126245 [GRCh38]
Chr2:235576803..243059659 [GRCh37]
Chr2:235241542..242717069 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:234906462-242065208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052671]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052671]|See cases [RCV000052671] Chr2:234906462..242065208 [GRCh38]
Chr2:235815106..243007359 [GRCh37]
Chr2:235479845..242656032 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235268768-242065208)x1 copy number loss See cases [RCV000052672] Chr2:235268768..242065208 [GRCh38]
Chr2:236177412..243007359 [GRCh37]
Chr2:235842151..242656032 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:231375505-242065208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052639]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052639]|See cases [RCV000052639] Chr2:231375505..242065208 [GRCh38]
Chr2:232240216..243007359 [GRCh37]
Chr2:231948460..242656032 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:232857728-242065349)x1 copy number loss See cases [RCV000052640] Chr2:232857728..242065349 [GRCh38]
Chr2:233722438..243007500 [GRCh37]
Chr2:233430682..242656173 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:233420162-242086301)x1 copy number loss See cases [RCV000052641] Chr2:233420162..242086301 [GRCh38]
Chr2:233995840..243028452 [GRCh37]
Chr2:233704084..242677125 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:233453611-242099155)x1 copy number loss See cases [RCV000052642] Chr2:233453611..242099155 [GRCh38]
Chr2:234362257..243041306 [GRCh37]
Chr2:234026996..242689979 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:234225537-241565907)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052975]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052975]|See cases [RCV000052975] Chr2:234225537..241565907 [GRCh38]
Chr2:235134181..242505322 [GRCh37]
Chr2:234798920..242153995 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235268768-242126245)x3 copy number gain See cases [RCV000052976] Chr2:235268768..242126245 [GRCh38]
Chr2:236177412..243059659 [GRCh37]
Chr2:235842151..242717069 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235563664-242086301)x3 copy number gain See cases [RCV000052977] Chr2:235563664..242086301 [GRCh38]
Chr2:236472308..243028452 [GRCh37]
Chr2:236137047..242677125 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237813997-240410487)x3 copy number gain See cases [RCV000052978] Chr2:237813997..240410487 [GRCh38]
Chr2:238722640..241349904 [GRCh37]
Chr2:238387379..240998577 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:188818195-242065208)x3 copy number gain See cases [RCV000052958] Chr2:188818195..242065208 [GRCh38]
Chr2:189682921..243007359 [GRCh37]
Chr2:189391166..242656032 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:190310736-241892770)x3 copy number gain See cases [RCV000052959] Chr2:190310736..241892770 [GRCh38]
Chr2:191175462..242834921 [GRCh37]
Chr2:190883707..242483594 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:193122313-241074980)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|See cases [RCV000052960] Chr2:193122313..241074980 [GRCh38]
Chr2:193987039..242014395 [GRCh37]
Chr2:193695284..241663068 [NCBI36]
Chr2:2q32.3-37.3		 pathogenic
GRCh38/hg38 2q36.1-37.3(chr2:223992431-242126245)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052972]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052972]|See cases [RCV000052972] Chr2:223992431..242126245 [GRCh38]
Chr2:224857148..243059659 [GRCh37]
Chr2:224565392..242717069 [NCBI36]
Chr2:2q36.1-37.3		 pathogenic
GRCh38/hg38 2q36.3-37.3(chr2:227803148-242086301)x3 copy number gain See cases [RCV000052973] Chr2:227803148..242086301 [GRCh38]
Chr2:228667864..243028452 [GRCh37]
Chr2:228376108..242677125 [NCBI36]
Chr2:2q36.3-37.3		 pathogenic
NM_001080835.1(PRR21):c.1019C>T (p.Ser340Leu) single nucleotide variant Malignant melanoma [RCV000060529] Chr2:240041964 [GRCh38]
Chr2:240981381 [GRCh37]
Chr2:240630054 [NCBI36]
Chr2:2q37.3		 not provided
GRCh37/hg19 2q37.3(chr2:239860877-241385960) copy number loss Poland anomaly [RCV001291955] Chr2:239860877..241385960 [GRCh37]
Chr2:2q37.3		 pathogenic
Single allele deletion Intellectual disability [RCV001293367] Chr2:237201756..243048760 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:238756369-241771051)x3 copy number gain See cases [RCV000133659] Chr2:238756369..241771051 [GRCh38]
Chr2:239665010..242710466 [GRCh37]
Chr2:239329749..242359139 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q36.3-37.3(chr2:228723579-241404867)x3 copy number gain See cases [RCV000134169] Chr2:228723579..241404867 [GRCh38]
Chr2:229588295..242344282 [GRCh37]
Chr2:229296539..241992955 [NCBI36]
Chr2:2q36.3-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237034476-242065208)x1 copy number loss See cases [RCV000135864] Chr2:237034476..242065208 [GRCh38]
Chr2:237943119..243007359 [GRCh37]
Chr2:237607858..242656032 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:236966763-242065208)x1 copy number loss See cases [RCV000135570] Chr2:236966763..242065208 [GRCh38]
Chr2:237875406..243007359 [GRCh37]
Chr2:237540145..242656032 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237232204-242065208)x1 copy number loss See cases [RCV000136566] Chr2:237232204..242065208 [GRCh38]
Chr2:238140847..243007359 [GRCh37]
Chr2:237805586..242656032 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q34-37.3(chr2:210579676-242126245)x3 copy number gain See cases [RCV000135934] Chr2:210579676..242126245 [GRCh38]
Chr2:211444400..243059659 [GRCh37]
Chr2:211152645..242717069 [NCBI36]
Chr2:2q34-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235028429-242066108)x1 copy number loss See cases [RCV000136968] Chr2:235028429..242066108 [GRCh38]
Chr2:235937073..243008259 [GRCh37]
Chr2:235601812..242656932 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:234835780-242065208)x1 copy number loss See cases [RCV000137069] Chr2:234835780..242065208 [GRCh38]
Chr2:235744424..243007359 [GRCh37]
Chr2:235409163..242656032 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235603604-241771051)x1 copy number loss See cases [RCV000136648] Chr2:235603604..241771051 [GRCh38]
Chr2:236512248..242710466 [GRCh37]
Chr2:236176987..242359139 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic|uncertain significance
GRCh38/hg38 2q37.3(chr2:238833519-242126245)x1 copy number loss See cases [RCV000138117] Chr2:238833519..242126245 [GRCh38]
Chr2:239742160..243059659 [GRCh37]
Chr2:239406907..242717069 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:237902870-242126251)x1 copy number loss See cases [RCV000139808] Chr2:237902870..242126251 [GRCh38]
Chr2:238811512..243059659 [GRCh37]
Chr2:238476251..242717075 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:236775762-242126251)x1 copy number loss See cases [RCV000139527] Chr2:236775762..242126251 [GRCh38]
Chr2:237684405..243059659 [GRCh37]
Chr2:237349144..242717075 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:236413722-242126251)x1 copy number loss See cases [RCV000139805] Chr2:236413722..242126251 [GRCh38]
Chr2:237322365..243059659 [GRCh37]
Chr2:236987104..242717075 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.2-37.3(chr2:235846916-241841232)x1 copy number loss See cases [RCV000141661] Chr2:235846916..241841232 [GRCh38]
Chr2:236755560..242783384 [GRCh37]
Chr2:236420299..242432057 [NCBI36]
Chr2:2q37.2-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:239507342-241841232)x1 copy number loss See cases [RCV000141691] Chr2:239507342..241841232 [GRCh38]
Chr2:240429036..242783384 [GRCh37]
Chr2:240093973..242432057 [NCBI36]
Chr2:2q37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:234159653-241841232)x1 copy number loss See cases [RCV000142291] Chr2:234159653..241841232 [GRCh38]
Chr2:235068297..242783384 [GRCh37]
Chr2:234733036..242432057 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:189436149-241841232)x3 copy number gain See cases [RCV000142307] Chr2:189436149..241841232 [GRCh38]
Chr2:190300875..242783384 [GRCh37]
Chr2:190009120..242432057 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q37.3(chr2:239642965-241841232)x1 copy number loss See cases [RCV000143423] Chr2:239642965..241841232 [GRCh38]
Chr2:240564659..242783384 [GRCh37]
Chr2:240229596..242432057 [NCBI36]
Chr2:2q37.3		 likely pathogenic
GRCh38/hg38 2q35-37.3(chr2:218101759-242126245)x3 copy number gain See cases [RCV000143216] Chr2:218101759..242126245 [GRCh38]
Chr2:218966482..243059659 [GRCh37]
Chr2:218674727..242717069 [NCBI36]
Chr2:2q35-37.3		 pathogenic
GRCh38/hg38 2q37.1-37.3(chr2:231770279-242126245)x1 copy number loss See cases [RCV000148260] Chr2:231770279..242126245 [GRCh38]
Chr2:232634989..243059659 [GRCh37]
Chr2:232343233..242717069 [NCBI36]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:239873381-243006013)x3 copy number gain See cases [RCV000167564] Chr2:239873381..243006013 [GRCh37]
Chr2:2q37.3		 pathogenic
NC_000002.12:g.(?_239048168)_(240879119_?)del deletion Primary hyperoxaluria, type I [RCV000186424] Chr2:239048168..240879119 [GRCh38]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:237816758-242783384)x1 copy number loss See cases [RCV000449023] Chr2:237816758..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:233784243-243040217)x1 copy number loss See cases [RCV000446034] Chr2:233784243..243040217 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240982124-241016654)x3 copy number gain See cases [RCV000446381] Chr2:240982124..241016654 [GRCh37]
Chr2:2q37.3		 likely benign
GRCh37/hg19 2q37.3(chr2:237938270-242783384)x1 copy number loss See cases [RCV000446532] Chr2:237938270..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:234495262-242783384)x1 copy number loss See cases [RCV000446061] Chr2:234495262..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240981290-240987642)x3 copy number gain See cases [RCV000447196] Chr2:240981290..240987642 [GRCh37]
Chr2:2q37.3		 benign
GRCh37/hg19 2q37.2-37.3(chr2:236285213-242783384)x1 copy number loss See cases [RCV000445750] Chr2:236285213..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:238072533-242783384)x1 copy number loss See cases [RCV000447929] Chr2:238072533..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236911223-242783384)x1 copy number loss See cases [RCV000447965] Chr2:236911223..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236577291-242783384)x1 copy number loss See cases [RCV000448691] Chr2:236577291..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:234495262-242783384)x1 copy number loss See cases [RCV000512077] Chr2:234495262..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240541136-242783384)x1 copy number loss See cases [RCV000510186] Chr2:240541136..242783384 [GRCh37]
Chr2:2q37.3		 likely pathogenic
GRCh37/hg19 2q37.3(chr2:239748306-242783384)x1 copy number loss See cases [RCV000510310] Chr2:239748306..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:235539337-242783384)x1 copy number loss See cases [RCV000511491] Chr2:235539337..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240630455-242783384)x1 copy number loss See cases [RCV000511956] Chr2:240630455..242783384 [GRCh37]
Chr2:2q37.3		 likely pathogenic
GRCh37/hg19 2q34-37.3(chr2:213518431-242783384)x3 copy number gain See cases [RCV000512009] Chr2:213518431..242783384 [GRCh37]
Chr2:2q34-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240161377-242783384)x1 copy number loss See cases [RCV000511227] Chr2:240161377..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240556675-241180768)x3 copy number gain See cases [RCV000511260] Chr2:240556675..241180768 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240141439-242783384)x3 copy number gain See cases [RCV000512298] Chr2:240141439..242783384 [GRCh37]
Chr2:2q37.3		 likely pathogenic
GRCh37/hg19 2q37.3(chr2:237545100-242783384)x1 copy number loss See cases [RCV000512231] Chr2:237545100..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240457943-242783384)x1 copy number loss not provided [RCV000682145] Chr2:240457943..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240076138-242783384)x1 copy number loss not provided [RCV000682146] Chr2:240076138..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:239884390-242783384)x1 copy number loss not provided [RCV000682148] Chr2:239884390..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:237480048-241611309)x1 copy number loss not provided [RCV000682151] Chr2:237480048..241611309 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q35-37.3(chr2:219225872-242016876)x3 copy number gain not provided [RCV000682170] Chr2:219225872..242016876 [GRCh37]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:235790256-242783384)x1 copy number loss not provided [RCV000682160] Chr2:235790256..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:234716425-242783384)x3 copy number gain not provided [RCV000682161] Chr2:234716425..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:238037759-243101834)x1 copy number loss not provided [RCV000740979] Chr2:238037759..243101834 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240981561-240987009)x0 copy number loss not provided [RCV000741025] Chr2:240981561..240987009 [GRCh37]
Chr2:2q37.3		 benign
GRCh37/hg19 2q37.3(chr2:239914717-242783384)x1 copy number loss not provided [RCV001005384] Chr2:239914717..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:239894072-243048760)x1 copy number loss See cases [RCV000790569] Chr2:239894072..243048760 [GRCh37]
Chr2:2q37.3		 pathogenic
NM_173351.2(OR6B3):c.330C>T (p.Thr110=) single nucleotide variant not provided [RCV000946701] Chr2:240045743 [GRCh38]
Chr2:240985160 [GRCh37]
Chr2:2q37.3		 likely benign
NM_173351.2(OR6B3):c.143C>T (p.Thr48Ile) single nucleotide variant not provided [RCV000946702] Chr2:240045930 [GRCh38]
Chr2:240985347 [GRCh37]
Chr2:2q37.3		 benign
GRCh37/hg19 2q37.3(chr2:238795602-242918203) copy number loss Chromosome 2q37 deletion syndrome [RCV000767788] Chr2:238795602..242918203 [GRCh37]
Chr2:2q37.3		 likely pathogenic
GRCh37/hg19 2q37.3(chr2:239071623-243048760) copy number loss Chromosome 2q37 deletion syndrome [RCV000767789] Chr2:239071623..243048760 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:237028693-242708080) copy number loss Chromosome 2q37 deletion syndrome [RCV000767787] Chr2:237028693..242708080 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:240112450-242783384)x1 copy number loss not provided [RCV001005385] Chr2:240112450..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:237265271-242783384)x3 copy number gain not provided [RCV001005380] Chr2:237265271..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
NM_173351.2(OR6B3):c.283G>A (p.Val95Ile) single nucleotide variant Inborn genetic diseases [RCV003250998] Chr2:240045790 [GRCh38]
Chr2:240985207 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.665C>A (p.Thr222Asn) single nucleotide variant Inborn genetic diseases [RCV003248256] Chr2:240045408 [GRCh38]
Chr2:240984825 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q36.3-37.3(chr2:230814690-242783384)x3 copy number gain not provided [RCV001007519] Chr2:230814690..242783384 [GRCh37]
Chr2:2q36.3-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236172348-241611309)x1 copy number loss not provided [RCV001007525] Chr2:236172348..241611309 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:235942616-242783384)x1 copy number loss not provided [RCV002472625] Chr2:235942616..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:234791927-242783384)x1 copy number loss not provided [RCV001007522] Chr2:234791927..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:238863455-243048760)x3 copy number gain See cases [RCV001194532] Chr2:238863455..243048760 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q37.1-37.3(chr2:233110452-243028452)x1 copy number loss Chromosome 2q37 deletion syndrome [RCV001263221] Chr2:233110452..243028452 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q31.2-37.3(chr2:178397959-243007457)x3 copy number gain See cases [RCV001263052] Chr2:178397959..243007457 [GRCh37]
Chr2:2q31.2-37.3		 pathogenic
Single allele deletion Chromosome 2q37 deletion syndrome [RCV002247720] Chr2:236710422..242106504 [GRCh38]
Chr2:2q37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:239436367-242783384)x1 copy number loss not provided [RCV001834263] Chr2:239436367..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
NM_173351.2(OR6B3):c.641C>A (p.Thr214Asn) single nucleotide variant Inborn genetic diseases [RCV003293653] Chr2:240045432 [GRCh38]
Chr2:240984849 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q37.3(chr2:240208466-243199373)x3 copy number gain not provided [RCV001827620] Chr2:240208466..243199373 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q37.3(chr2:237499041-242783384)x1 copy number loss not provided [RCV001827851] Chr2:237499041..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
NC_000002.11:g.(?_236403331)_(242801596_?)dup duplication not provided [RCV001879163] Chr2:236403331..242801596 [GRCh37]
Chr2:2q37.2-37.3		 uncertain significance
NC_000002.11:g.(?_236877086)_(242801596_?)del deletion not provided [RCV001956380] Chr2:236877086..242801596 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
NC_000002.11:g.(?_238233417)_(242801596_?)del deletion D-2-hydroxyglutaric aciduria 1 [RCV003120750]|Hereditary spastic paraplegia 30 [RCV001920651]|not provided [RCV001920650] Chr2:238233417..242801596 [GRCh37]
Chr2:2q37.3		 pathogenic|uncertain significance|no classifications from unflagged records
NC_000002.11:g.(?_238233417)_(242800990_?)dup duplication D-2-hydroxyglutaric aciduria 1 [RCV001918744]|Hereditary spastic paraplegia 30 [RCV001942893] Chr2:238233417..242800990 [GRCh37]
Chr2:2q37.3		 uncertain significance
NC_000002.11:g.(?_236403331)_(242801596_?)del deletion Bethlem myopathy 1 [RCV003113452] Chr2:236403331..242801596 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.1-37.3(chr2:233227837-242783384) copy number loss Chromosome 2q37 deletion syndrome [RCV002280739] Chr2:233227837..242783384 [GRCh37]
Chr2:2q37.1-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236472789-242783384) copy number loss Chromosome 2q37 deletion syndrome [RCV002280740] Chr2:236472789..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:239229304-243199373)x1 copy number loss not provided [RCV002293050] Chr2:239229304..243199373 [GRCh37]
Chr2:2q37.3		 pathogenic
NM_173351.2(OR6B3):c.689C>T (p.Ser230Leu) single nucleotide variant Inborn genetic diseases [RCV003253793] Chr2:240045384 [GRCh38]
Chr2:240984801 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.56C>T (p.Thr19Met) single nucleotide variant Inborn genetic diseases [RCV002991025] Chr2:240046017 [GRCh38]
Chr2:240985434 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q37.2-37.3(chr2:236878509-242783384)x1 copy number loss not provided [RCV002473939] Chr2:236878509..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
NM_173351.2(OR6B3):c.314G>C (p.Ser105Thr) single nucleotide variant Inborn genetic diseases [RCV002729929] Chr2:240045759 [GRCh38]
Chr2:240985176 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.934G>A (p.Val312Ile) single nucleotide variant Inborn genetic diseases [RCV003000919] Chr2:240045139 [GRCh38]
Chr2:240984556 [GRCh37]
Chr2:2q37.3		 likely benign
NM_173351.2(OR6B3):c.655G>T (p.Ala219Ser) single nucleotide variant Inborn genetic diseases [RCV003000699] Chr2:240045418 [GRCh38]
Chr2:240984835 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.848C>T (p.Pro283Leu) single nucleotide variant Inborn genetic diseases [RCV002798967] Chr2:240045225 [GRCh38]
Chr2:240984642 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.471G>T (p.Met157Ile) single nucleotide variant Inborn genetic diseases [RCV002757416] Chr2:240045602 [GRCh38]
Chr2:240985019 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.656C>G (p.Ala219Gly) single nucleotide variant Inborn genetic diseases [RCV003000700] Chr2:240045417 [GRCh38]
Chr2:240984834 [GRCh37]
Chr2:2q37.3		 likely benign
NM_173351.2(OR6B3):c.581C>A (p.Thr194Asn) single nucleotide variant Inborn genetic diseases [RCV002767506] Chr2:240045492 [GRCh38]
Chr2:240984909 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.130G>T (p.Ala44Ser) single nucleotide variant Inborn genetic diseases [RCV002664674] Chr2:240045943 [GRCh38]
Chr2:240985360 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.569C>T (p.Thr190Met) single nucleotide variant Inborn genetic diseases [RCV002668146] Chr2:240045504 [GRCh38]
Chr2:240984921 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.286G>A (p.Gly96Arg) single nucleotide variant Inborn genetic diseases [RCV002699598] Chr2:240045787 [GRCh38]
Chr2:240985204 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.331G>A (p.Glu111Lys) single nucleotide variant Inborn genetic diseases [RCV002964476] Chr2:240045742 [GRCh38]
Chr2:240985159 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.830T>G (p.Leu277Trp) single nucleotide variant Inborn genetic diseases [RCV002960436] Chr2:240045243 [GRCh38]
Chr2:240984660 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.739G>A (p.Val247Met) single nucleotide variant Inborn genetic diseases [RCV003214318] Chr2:240045334 [GRCh38]
Chr2:240984751 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.856A>G (p.Asn286Asp) single nucleotide variant Inborn genetic diseases [RCV003206149] Chr2:240045217 [GRCh38]
Chr2:240984634 [GRCh37]
Chr2:2q37.3		 uncertain significance
NM_173351.2(OR6B3):c.500C>T (p.Thr167Met) single nucleotide variant Inborn genetic diseases [RCV003342424] Chr2:240045573 [GRCh38]
Chr2:240984990 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q37.3(chr2:240827284-241048926)x3 copy number gain not provided [RCV003484098] Chr2:240827284..241048926 [GRCh37]
Chr2:2q37.3		 uncertain significance
GRCh37/hg19 2q35-37.3(chr2:218376403-242783384)x3 copy number gain not provided [RCV003484087] Chr2:218376403..242783384 [GRCh37]
Chr2:2q35-37.3		 pathogenic
GRCh37/hg19 2q37.3(chr2:238460671-242783384)x1 copy number loss not provided [RCV003485294] Chr2:238460671..242783384 [GRCh37]
Chr2:2q37.3		 pathogenic
Single allele duplication not provided [RCV003448672] Chr2:230077026..243049549 [GRCh37]
Chr2:2q36.3-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236057846-242783384)x1 copy number loss not specified [RCV003986344] Chr2:236057846..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
GRCh37/hg19 2q37.2-37.3(chr2:236726690-242783384)x1 copy number loss not specified [RCV003986335] Chr2:236726690..242783384 [GRCh37]
Chr2:2q37.2-37.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:57
Interacting mature miRNAs:58
Transcripts:ENST00000319423
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
OR6B3__5930  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372240,984,381 - 240,985,019UniSTSGRCh37
Build 362240,633,054 - 240,633,692RGDNCBI36
Celera2234,657,403 - 234,658,041RGD
HuRef2232,742,254 - 232,742,892UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 171 172 171
Low 7 13 3 6 452 7 517 3 321 2 3 18 432
Below cutoff 227 251 69 50 71 14 539 256 1207 13 183 69 37 142 269

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000319423   ⟹   ENSP00000322435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2240,045,077 - 240,046,072 (-)Ensembl
RefSeq Acc Id: ENST00000641019   ⟹   ENSP00000493035
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2240,044,571 - 240,053,521 (-)Ensembl
RefSeq Acc Id: NM_173351   ⟹   NP_775486
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382240,044,571 - 240,053,521 (-)NCBI
GRCh372240,984,494 - 240,985,489 (-)RGD
Build 362240,633,167 - 240,634,162 (-)NCBI Archive
Celera2234,657,516 - 234,658,511 (-)RGD
HuRef2232,742,367 - 232,743,362 (-)RGD
CHM1_12240,990,010 - 240,991,005 (-)NCBI
T2T-CHM13v2.02240,537,284 - 240,546,234 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_775486 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AFI24894 (Get FASTA)   NCBI Sequence Viewer  
  ALI87636 (Get FASTA)   NCBI Sequence Viewer  
  BAC05888 (Get FASTA)   NCBI Sequence Viewer  
  DAA04687 (Get FASTA)   NCBI Sequence Viewer  
  EAW71177 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000493035
  ENSP00000493035.1
GenBank Protein Q8NGW1 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_775486   ⟸   NM_173351
- UniProtKB: Q6IFH3 (UniProtKB/Swiss-Prot),   Q8NGW1 (UniProtKB/Swiss-Prot),   A0A126GW38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000493035   ⟸   ENST00000641019
RefSeq Acc Id: ENSP00000322435   ⟸   ENST00000319423
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8NGW1-F1-model_v2 AlphaFold Q8NGW1 1-331 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15042 AgrOrtholog
COSMIC OR6B3 COSMIC
Ensembl Genes ENSG00000178586 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000641019 ENTREZGENE
  ENST00000641019.2 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000178586 GTEx
HGNC ID HGNC:15042 ENTREZGENE
Human Proteome Map OR6B3 Human Proteome Map
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:150681 UniProtKB/Swiss-Prot
NCBI Gene 150681 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6B2-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA32578 PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A126GW38 ENTREZGENE, UniProtKB/TrEMBL
  I0EZ58_HUMAN UniProtKB/TrEMBL
  OR6B3_HUMAN UniProtKB/Swiss-Prot
  Q6IFH3 ENTREZGENE
  Q8NGW1 ENTREZGENE
UniProt Secondary Q6IFH3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-15 OR6B3  olfactory receptor family 6 subfamily B member 3  OR6B3  olfactory receptor, family 6, subfamily B, member 3  Symbol and/or name change 5135510 APPROVED