Tnnc2 (troponin C2, fast skeletal type) - Rat Genome Database

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Gene: Tnnc2 (troponin C2, fast skeletal type) Rattus norvegicus
Analyze
Symbol: Tnnc2
Name: troponin C2, fast skeletal type
RGD ID: 1311973
Description: Predicted to enable calcium ion binding activity. Predicted to contribute to actin binding activity. Predicted to be involved in regulation of muscle contraction and skeletal muscle contraction. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in congenital myopathy 15. Orthologous to human TNNC2 (troponin C2, fast skeletal type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296369; skeletal troponin C; troponin C type 2 (fast); troponin C, skeletal muscle; troponin C2, fast
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,932,611 - 173,935,339 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,932,611 - 173,935,339 (-)EnsemblGRCr8
mRatBN7.23153,513,272 - 153,516,033 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,513,271 - 153,516,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,321,952 - 157,324,670 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,820,922 - 165,823,640 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,564,699 - 163,567,417 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,243,607 - 161,246,335 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)Ensemblrn6Rnor6.0
Rnor_5.03167,429,345 - 167,430,429 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,807,133 - 155,808,219 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,121,028 - 152,123,756 (-)NCBICelera
RGSC_v3.13155,713,032 - 155,715,733 (-)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
genistein  (ISO)
glycidol  (EXP)
graphite  (ISO)
indometacin  (ISO)
ketamine  (EXP)
Licochalcone B  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
pioglitazone  (ISO)
progesterone  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
Soman  (EXP)
spermine  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triazines  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
troponin complex  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway   (ISO)
calcium/calcium-mediated signaling pathway  (IEA,ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Calcium, troponin, calmodulin, S100 proteins: from myocardial basics to new therapeutic strategies. Schaub MC and Heizmann CW, Biochem Biophys Res Commun. 2008 Apr 25;369(1):247-64. Epub 2007 Oct 25.
Additional References at PubMed
PMID:6179945   PMID:16839517   PMID:17194691   PMID:19182904  


Genomics

Comparative Map Data
Tnnc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,932,611 - 173,935,339 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,932,611 - 173,935,339 (-)EnsemblGRCr8
mRatBN7.23153,513,272 - 153,516,033 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,513,271 - 153,516,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,321,952 - 157,324,670 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,820,922 - 165,823,640 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,564,699 - 163,567,417 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,243,607 - 161,246,335 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)Ensemblrn6Rnor6.0
Rnor_5.03167,429,345 - 167,430,429 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,807,133 - 155,808,219 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,121,028 - 152,123,756 (-)NCBICelera
RGSC_v3.13155,713,032 - 155,715,733 (-)NCBI
Cytogenetic Map3q42NCBI
TNNC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,823,214 - 45,833,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,823,214 - 45,833,745 (-)Ensemblhg38GRCh38
GRCh372044,451,853 - 44,455,951 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,885,260 - 43,889,360 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342043,885,263 - 43,889,360NCBI
Celera2041,162,347 - 41,166,448 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,193,614 - 41,197,713 (-)NCBIHuRef
CHM1_12044,354,991 - 44,359,091 (-)NCBICHM1_1
T2T-CHM13v2.02047,559,705 - 47,569,768 (-)NCBIT2T-CHM13v2.0
Tnnc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,619,081 - 164,621,654 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,619,081 - 164,621,887 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382164,777,161 - 164,779,734 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,777,161 - 164,779,967 (-)Ensemblmm10GRCm38
MGSCv372164,602,661 - 164,605,234 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362164,468,366 - 164,470,939 (-)NCBIMGSCv36mm8
Celera2170,714,468 - 170,717,041 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Tnnc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,466,579 - 11,469,123 (+)Ensembl
ChiLan1.0NW_00495544511,466,579 - 11,469,123 (+)NCBIChiLan1.0ChiLan1.0
TNNC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,565,060 - 51,575,559 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,558,160 - 51,568,463 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,162,502 - 42,172,829 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,249,725 - 43,260,984 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,249,725 - 43,254,134 (-)EnsemblpanPan2panpan1.1
TNNC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,136,644 - 33,139,289 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,128,290 - 33,163,050 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2432,663,877 - 32,666,541 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02433,847,135 - 33,849,798 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,847,144 - 33,849,791 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,105,691 - 33,108,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,220,760 - 33,223,430 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,759,900 - 33,762,559 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tnnc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,742,934 - 191,745,960 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,196,536 - 7,199,649 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,196,576 - 7,199,603 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNNC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,024,687 - 48,028,651 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11748,025,621 - 48,026,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,671,689 - 53,672,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNNC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,051,708 - 18,063,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,061,492 - 18,062,971 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605066,691,630 - 66,703,067 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnnc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15153,178,318 - 153,181,219 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:81
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000020348
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat

Markers in Region
Tncs  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83173,933,153 - 173,933,807 (+)Marker Load Pipeline
mRatBN7.23153,513,814 - 153,514,468 (+)MAPPERmRatBN7.2
Rnor_6.03161,244,150 - 161,244,803NCBIRnor6.0
Rnor_5.03167,429,748 - 167,430,401UniSTSRnor5.0
RGSC_v3.43155,807,536 - 155,808,189UniSTSRGSC3.4
Celera3152,121,571 - 152,122,224UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 65 152 90 89 58 86 58 6 337 184 11 129 72 92 31 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC105815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ273679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J00793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020348   ⟹   ENSRNOP00000020348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3173,932,611 - 173,935,339 (-)Ensembl
mRatBN7.2 Ensembl3153,513,276 - 153,516,029 (-)Ensembl
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098001   ⟹   ENSRNOP00000084039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,513,271 - 153,514,652 (-)Ensembl
RefSeq Acc Id: NM_001037351   ⟹   NP_001032428
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,932,611 - 173,935,339 (-)NCBI
mRatBN7.23153,513,272 - 153,516,000 (-)NCBI
Rnor_6.03161,243,607 - 161,246,335 (-)NCBI
Rnor_5.03167,429,345 - 167,430,429 (-)NCBI
RGSC_v3.43155,807,133 - 155,808,219 (-)RGD
Celera3152,121,028 - 152,123,756 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001032428 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB51540 (Get FASTA)   NCBI Sequence Viewer  
  EDL96496 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020348
  ENSRNOP00000020348.5
RefSeq Acc Id: NP_001032428   ⟸   NM_001037351
- UniProtKB: Q304F3 (UniProtKB/TrEMBL),   F2Z3S8 (UniProtKB/TrEMBL),   A6JXB3 (UniProtKB/TrEMBL),   A0A8I5ZWE4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020348   ⟸   ENSRNOT00000020348
Ensembl Acc Id: ENSRNOP00000084039   ⟸   ENSRNOT00000098001
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q304F3-F1-model_v2 AlphaFold Q304F3 1-160 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692665
Promoter ID:EPDNEW_R3189
Type:multiple initiation site
Name:Tnnc2_1
Description:troponin C2, fast skeletal type
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,246,306 - 161,246,366EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311973 AgrOrtholog
BioCyc Gene G2FUF-46829 BioCyc
Ensembl Genes ENSRNOG00000015155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020348 ENTREZGENE
  ENSRNOT00000020348.8 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro Ca-Reg_Muscle_Contr_Cell_Proc UniProtKB/TrEMBL
  EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
KEGG Report rno:296369 UniProtKB/TrEMBL
NCBI Gene 296369 ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/TrEMBL
  TROPONIN C2, FAST SKELETAL TYPE UniProtKB/TrEMBL
Pfam EF_hand_5 UniProtKB/TrEMBL
PhenoGen Tnnc2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015155 RatGTEx
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8I5ZWE4 ENTREZGENE, UniProtKB/TrEMBL
  A6JXB3 ENTREZGENE
  F2Z3S8 ENTREZGENE
  Q304F3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6JXB3 UniProtKB/TrEMBL
  F2Z3S8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Tnnc2  troponin C2, fast skeletal type  Tnnc2  troponin C type 2 (fast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Tnnc2  troponin C type 2 (fast)  Tnnc2  troponin C2, fast  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Tnnc2  troponin C2, fast  Tnnc2  troponin C type 2 (fast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tnnc2  troponin C type 2 (fast)    troponin C2, fast  Name updated 1299863 APPROVED
2005-12-06 Tnnc2  troponin C2, fast  Tnnc2_predicted  troponin C2, fast (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tnnc2_predicted  troponin C2, fast (predicted)      Symbol and Name status set to approved 70820 APPROVED