Cnksr1 (connector enhancer of kinase suppressor of Ras 1) - Rat Genome Database

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Gene: Cnksr1 (connector enhancer of kinase suppressor of Ras 1) Rattus norvegicus
Analyze
Symbol: Cnksr1
Name: connector enhancer of kinase suppressor of Ras 1
RGD ID: 1311879
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to be located in cell cortex. Orthologous to human CNKSR1 (connector enhancer of kinase suppressor of Ras 1); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; interleukin-3 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC298545; MGC124829
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,731,222 - 151,742,049 (-)NCBIGRCr8
mRatBN7.25146,447,495 - 146,458,332 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,447,497 - 146,458,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,149,245 - 149,159,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,919,634 - 150,930,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,905,459 - 150,916,094 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,447,348 - 152,458,005 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,446,845 - 152,458,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,206,363 - 156,217,020 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,972,551 - 152,983,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15152,982,589 - 152,993,370 (-)NCBI
Celera5144,865,185 - 144,875,842 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. An ATIPical family of angiotensin II AT2 receptor-interacting proteins. Rodrigues-Ferreira S and Nahmias C, Trends Endocrinol Metab. 2010 Nov;21(11):684-90.
Additional References at PubMed
PMID:12477932   PMID:14749388   PMID:15075335  


Genomics

Comparative Map Data
Cnksr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,731,222 - 151,742,049 (-)NCBIGRCr8
mRatBN7.25146,447,495 - 146,458,332 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,447,497 - 146,458,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,149,245 - 149,159,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,919,634 - 150,930,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,905,459 - 150,916,094 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,447,348 - 152,458,005 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,446,845 - 152,458,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,206,363 - 156,217,020 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,972,551 - 152,983,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15152,982,589 - 152,993,370 (-)NCBI
Celera5144,865,185 - 144,875,842 (-)NCBICelera
Cytogenetic Map5q36NCBI
CNKSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,177,491 - 26,189,884 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,177,484 - 26,189,884 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,503,982 - 26,516,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,376,590 - 26,388,962 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,188,144 - 26,200,515NCBI
Celera124,900,351 - 24,912,738 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,758,021 - 24,770,408 (+)NCBIHuRef
CHM1_1126,617,199 - 26,629,585 (+)NCBICHM1_1
T2T-CHM13v2.0126,014,921 - 26,027,308 (+)NCBIT2T-CHM13v2.0
Cnksr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,955,352 - 133,965,737 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,955,352 - 133,965,710 (-)EnsemblGRCm39 Ensembl
GRCm384134,228,041 - 134,238,416 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,228,041 - 134,238,399 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,783,957 - 133,794,314 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,500,118 - 133,510,475 (-)NCBIMGSCv36mm8
MGSCv364131,800,745 - 131,810,306 (-)NCBIMGSCv36mm8
Celera4132,407,888 - 132,418,211 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.5NCBI
Cnksr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,624,306 - 5,634,923 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,624,334 - 5,634,861 (+)NCBIChiLan1.0ChiLan1.0
CNKSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,681,749 - 200,700,402 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,779,866 - 199,798,352 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,438,092 - 25,450,953 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,505,376 - 26,517,561 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,505,513 - 26,517,225 (+)Ensemblpanpan1.1panPan2
CNKSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,805,333 - 73,814,711 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,805,710 - 73,814,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,381,662 - 70,391,005 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,368,429 - 74,377,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,368,438 - 74,389,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,192,826 - 71,202,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,198,576 - 72,207,918 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,202,496 - 73,211,838 (-)NCBIUU_Cfam_GSD_1.0
Cnksr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,872,995 - 44,882,216 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,699,819 - 10,706,591 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,697,777 - 10,706,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNKSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,598,372 - 83,608,607 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,598,363 - 83,608,617 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,200,943 - 77,208,114 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNKSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,577,470 - 106,596,544 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,577,809 - 106,589,788 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,828,678 - 9,841,637 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnksr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476410,234,670 - 10,253,631 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476410,223,039 - 10,253,937 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cnksr1
61 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:285
Count of miRNA genes:174
Interacting mature miRNAs:192
Transcripts:ENSRNOT00000031225
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

Markers in Region
BI294230  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25146,447,674 - 146,447,832 (+)MAPPERmRatBN7.2
Rnor_6.05152,447,528 - 152,447,685NCBIRnor6.0
Rnor_5.05156,206,543 - 156,206,700UniSTSRnor5.0
RGSC_v3.45152,972,731 - 152,972,888UniSTSRGSC3.4
Celera5144,865,365 - 144,865,522UniSTS
RH 3.4 Map5986.1UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 3 14 1 3
Low 1 31 14 6 9 6 8 8 16 21 40 8 8
Below cutoff 10 42 34 10 34 52

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000031225   ⟹   ENSRNOP00000029346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,447,497 - 146,458,153 (-)Ensembl
Rnor_6.0 Ensembl5152,446,845 - 152,458,023 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097555   ⟹   ENSRNOP00000095433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,447,497 - 146,458,212 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105866   ⟹   ENSRNOP00000088159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5146,447,497 - 146,458,153 (-)Ensembl
RefSeq Acc Id: NM_001039011   ⟹   NP_001034100
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,741,879 (-)NCBI
mRatBN7.25146,447,495 - 146,458,153 (-)NCBI
Rnor_6.05152,447,348 - 152,458,005 (-)NCBI
Rnor_5.05156,206,363 - 156,217,020 (-)NCBI
RGSC_v3.45152,972,551 - 152,983,208 (-)RGD
Celera5144,865,185 - 144,875,842 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109635   ⟹   XP_038965563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,742,049 (-)NCBI
mRatBN7.25146,447,495 - 146,458,323 (-)NCBI
RefSeq Acc Id: XM_063287450   ⟹   XP_063143520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,742,049 (-)NCBI
RefSeq Acc Id: XM_063287451   ⟹   XP_063143521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,742,049 (-)NCBI
RefSeq Acc Id: XM_063287452   ⟹   XP_063143522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,741,555 (-)NCBI
RefSeq Acc Id: XM_063287453   ⟹   XP_063143523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85151,731,222 - 151,741,226 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001034100   ⟸   NM_001039011
- UniProtKB: Q499S0 (UniProtKB/TrEMBL),   A6IT10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000029346   ⟸   ENSRNOT00000031225
RefSeq Acc Id: XP_038965563   ⟸   XM_039109635
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AI85 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000088159   ⟸   ENSRNOT00000105866
RefSeq Acc Id: ENSRNOP00000095433   ⟸   ENSRNOT00000097555
RefSeq Acc Id: XP_063143521   ⟸   XM_063287451
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143520   ⟸   XM_063287450
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143522   ⟸   XM_063287452
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143523   ⟸   XM_063287453
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AN25 (UniProtKB/TrEMBL)
Protein Domains
CRIC   PH   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8W8-F1-model_v2 AlphaFold G3V8W8 1-704 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694131
Promoter ID:EPDNEW_R4656
Type:initiation region
Name:Cnksr1_1
Description:connector enhancer of kinase suppressor of Ras 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05152,458,026 - 152,458,086EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311879 AgrOrtholog
BioCyc Gene G2FUF-39591 BioCyc
Ensembl Genes ENSRNOG00000022838 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031225 ENTREZGENE
  ENSRNOT00000031225.5 UniProtKB/TrEMBL
  ENSRNOT00000097555.1 UniProtKB/TrEMBL
  ENSRNOT00000105866 ENTREZGENE
  ENSRNOT00000105866.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934518 IMAGE-MGC_LOAD
InterPro CRIC_domain UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed UniProtKB/TrEMBL
KEGG Report rno:298545 UniProtKB/TrEMBL
MGC_CLONE MGC:124829 IMAGE-MGC_LOAD
NCBI Gene 298545 ENTREZGENE
PANTHER CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS UniProtKB/TrEMBL
  CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 UniProtKB/TrEMBL
Pfam CRIC_ras_sig UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Cnksr1 PhenoGen
PROSITE CRIC UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022838 RatGTEx
SMART SAM UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SAM_homology UniProtKB/TrEMBL
UniProt A0A8I6AI85 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN25 ENTREZGENE, UniProtKB/TrEMBL
  A6IT10 ENTREZGENE, UniProtKB/TrEMBL
  G3V8W8_RAT UniProtKB/TrEMBL
  Q499S0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Cnksr1  connector enhancer of kinase suppressor of Ras 1  Cnksr1_predicted  connector enhancer of kinase suppressor of Ras 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cnksr1_predicted  connector enhancer of kinase suppressor of Ras 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED