Vasp (vasodilator-stimulated phosphoprotein) - Rat Genome Database

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Gene: Vasp (vasodilator-stimulated phosphoprotein) Rattus norvegicus
Analyze
Symbol: Vasp
Name: vasodilator-stimulated phosphoprotein
RGD ID: 1311542
Description: Predicted to enable profilin binding activity. Predicted to be involved in actin polymerization or depolymerization; nervous system development; and positive regulation of actin filament polymerization. Predicted to act upstream of or within actin cytoskeleton organization. Is active in glutamatergic synapse and postsynapse. Orthologous to human VASP (vasodilator stimulated phosphoprotein); PARTICIPATES IN E-cadherin signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361517
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,038,026 - 88,053,783 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,038,037 - 88,058,650 (-)EnsemblGRCr8
mRatBN7.2178,910,009 - 78,925,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,299,066 - 84,313,957 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,856,629 - 92,871,541 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,054,149 - 86,069,040 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,170,608 - 80,185,882 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)Ensemblrn6Rnor6.0
Rnor_5.0181,437,091 - 81,452,900 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,621,494 - 78,636,762 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,372,332 - 73,387,227 (-)NCBICelera
RGSC_v3.1178,699,598 - 78,715,028 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-(4-chlorophenylthio)-cGMP  (EXP,ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
ADP  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benomyl  (EXP)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bortezomib  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (EXP)
clopidogrel  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
DDE  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flusilazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furfural  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hemin  (EXP)
indometacin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nebivolol  (EXP)
nickel atom  (ISO)
nitroglycerin  (EXP,ISO)
okadaic acid  (ISO)
oxycodone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
pentaerythritol tetranitrate  (EXP)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (EXP)
progesterone  (ISO)
propiconazole  (EXP)
prostaglandin E1  (ISO)
prostaglandin E2  (ISO)
resveratrol  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (EXP)
SB 203580  (ISO)
SB 431542  (ISO)
silibinin  (ISO)
Silidianin  (ISO)
silychristin  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
staurosporine  (ISO)
sucrose  (EXP)
sulfadimethoxine  (EXP)
sulindac sulfone  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. Chazeau A, etal., EMBO J. 2014 Dec 1;33(23):2745-64. doi: 10.15252/embj.201488837. Epub 2014 Oct 7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15148305   PMID:15294161   PMID:15371503   PMID:17914456   PMID:18571642   PMID:19056867   PMID:19442672   PMID:20458337   PMID:20599605   PMID:21423176   PMID:23153535  
PMID:24580804   PMID:24779009   PMID:24894047   PMID:25468996   PMID:26221026   PMID:26264698   PMID:27957528   PMID:28376489   PMID:31505169  


Genomics

Comparative Map Data
Vasp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,038,026 - 88,053,783 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,038,037 - 88,058,650 (-)EnsemblGRCr8
mRatBN7.2178,910,009 - 78,925,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,299,066 - 84,313,957 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,856,629 - 92,871,541 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,054,149 - 86,069,040 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,170,608 - 80,185,882 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)Ensemblrn6Rnor6.0
Rnor_5.0181,437,091 - 81,452,900 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,621,494 - 78,636,762 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,372,332 - 73,387,227 (-)NCBICelera
RGSC_v3.1178,699,598 - 78,715,028 (-)NCBI
Cytogenetic Map1q21NCBI
VASP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,507,479 - 45,526,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,506,579 - 45,526,991 (+)Ensemblhg38GRCh38
GRCh371946,010,737 - 46,030,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,702,528 - 50,722,081 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341950,702,527 - 50,722,078NCBI
Celera1942,816,794 - 42,836,352 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,440,143 - 42,459,463 (+)NCBIHuRef
CHM1_11946,013,932 - 46,033,484 (+)NCBICHM1_1
T2T-CHM13v2.01948,334,741 - 48,354,257 (+)NCBIT2T-CHM13v2.0
Vasp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,990,854 - 19,005,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,990,854 - 19,005,742 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38719,256,929 - 19,271,854 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,256,929 - 19,271,817 (-)Ensemblmm10GRCm38
MGSCv37719,842,278 - 19,857,203 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36718,416,239 - 18,431,669 (-)NCBIMGSCv36mm8
Celera716,669,928 - 16,684,971 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.51NCBI
Vasp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557421,911 - 34,197 (+)Ensembl
ChiLan1.0NW_00495557421,569 - 33,705 (+)NCBIChiLan1.0ChiLan1.0
VASP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,668,472 - 51,688,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,540,746 - 53,560,217 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,457,222 - 42,476,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,053,567 - 51,072,551 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,053,567 - 51,072,553 (+)EnsemblpanPan2panpan1.1
VASP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,050,154 - 110,063,125 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,050,154 - 110,062,827 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1109,534,415 - 109,547,108 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01110,582,754 - 110,595,760 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,582,757 - 110,595,733 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,258,575 - 110,271,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,892,681 - 109,905,376 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,762,040 - 110,774,746 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101973767
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,575,109 - 17,597,696 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,932,475 - 1,947,069 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049367061,923,602 - 1,928,630 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,923,172 - 1,945,046 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VASP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,872,812 - 51,886,724 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1651,872,810 - 51,886,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
VASP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,954,212 - 38,974,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,954,014 - 38,975,108 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607318,575,539 - 18,596,231 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vasp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,619,134 - 7,630,943 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248327,619,211 - 7,631,576 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Vasp
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12171,345,745 - 171,361,543 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Vasp
98 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:63
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000022214
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
AA956278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,910,138 - 78,910,327 (+)MAPPERmRatBN7.2
Rnor_6.0180,170,738 - 80,170,926NCBIRnor6.0
Rnor_5.0181,437,221 - 81,437,409UniSTSRnor5.0
RGSC_v3.4178,621,618 - 78,621,806UniSTSRGSC3.4
Celera173,372,456 - 73,372,644UniSTS
RH 3.4 Map1818.2UniSTS
Cytogenetic Map1q21UniSTS
BF405517  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,912,681 - 78,912,786 (+)MAPPERmRatBN7.2
Rnor_6.0180,173,281 - 80,173,385NCBIRnor6.0
Rnor_5.0181,439,764 - 81,439,868UniSTSRnor5.0
RGSC_v3.4178,624,161 - 78,624,265UniSTSRGSC3.4
Celera173,374,999 - 73,375,103UniSTS
RH 3.4 Map1818.3UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_199372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005487868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC168841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000022214   ⟹   ENSRNOP00000022214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,038,037 - 88,058,650 (-)Ensembl
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)Ensembl
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088676   ⟹   ENSRNOP00000074940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,038,037 - 88,046,126 (-)Ensembl
mRatBN7.2 Ensembl178,910,020 - 78,918,140 (-)Ensembl
Rnor_6.0 Ensembl180,171,404 - 80,178,708 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096980   ⟹   ENSRNOP00000088421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,020 - 78,919,412 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107990   ⟹   ENSRNOP00000089122
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,020 - 78,919,412 (-)Ensembl
RefSeq Acc Id: NM_001108475   ⟹   NP_001101945
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,032 - 88,052,955 (-)NCBI
mRatBN7.2178,910,015 - 78,924,940 (-)NCBI
Rnor_6.0180,170,614 - 80,185,882 (-)NCBI
Rnor_5.0181,437,091 - 81,452,900 (-)NCBI
RGSC_v3.4178,621,494 - 78,636,762 (-)RGD
Celera173,372,332 - 73,387,227 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081727   ⟹   XP_038937655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,454 (-)NCBI
RefSeq Acc Id: XM_039081733   ⟹   XP_038937661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,782 (-)NCBI
mRatBN7.2178,910,009 - 78,925,789 (-)NCBI
RefSeq Acc Id: XM_039081738   ⟹   XP_038937666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,687 (-)NCBI
RefSeq Acc Id: XM_039081741   ⟹   XP_038937669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,469 (-)NCBI
mRatBN7.2178,910,009 - 78,924,692 (-)NCBI
RefSeq Acc Id: XM_039081742   ⟹   XP_038937670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,783 (-)NCBI
mRatBN7.2178,910,009 - 78,925,791 (-)NCBI
RefSeq Acc Id: XM_039081746   ⟹   XP_038937674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,470 (-)NCBI
mRatBN7.2178,910,009 - 78,924,694 (-)NCBI
RefSeq Acc Id: XR_005487868
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,454 (-)NCBI
RefSeq Acc Id: XR_010054316
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,782 (-)NCBI
RefSeq Acc Id: XR_010054317
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
RefSeq Acc Id: NP_001101945   ⟸   NM_001108475
- UniProtKB: B5DEX4 (UniProtKB/TrEMBL),   A0A8I6A7U4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022214   ⟸   ENSRNOT00000022214
Ensembl Acc Id: ENSRNOP00000074940   ⟸   ENSRNOT00000088676
RefSeq Acc Id: XP_038937670   ⟸   XM_039081742
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038937661   ⟸   XM_039081733
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937674   ⟸   XM_039081746
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937669   ⟸   XM_039081741
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937666   ⟸   XM_039081738
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937655   ⟸   XM_039081727
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089122   ⟸   ENSRNOT00000107990
Ensembl Acc Id: ENSRNOP00000088421   ⟸   ENSRNOT00000096980
Protein Domains
WH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9C0-F1-model_v2 AlphaFold A0A0G2K9C0 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689765
Promoter ID:EPDNEW_R290
Type:multiple initiation site
Name:Vasp_1
Description:vasodilator-stimulated phosphoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,185,768 - 80,185,828EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311542 AgrOrtholog
BioCyc Gene G2FUF-60518 BioCyc
Ensembl Genes ENSRNOG00000016367 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022214 ENTREZGENE
  ENSRNOT00000022214.9 UniProtKB/TrEMBL
  ENSRNOT00000088676 ENTREZGENE
  ENSRNOT00000088676.3 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro EVH1 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Vasodilator_phosphoprotein UniProtKB/TrEMBL
  VASP_sf UniProtKB/TrEMBL
  VASP_tetra UniProtKB/TrEMBL
KEGG Report rno:361517 UniProtKB/TrEMBL
NCBI Gene 361517 ENTREZGENE
PANTHER PTHR11202:SF12 UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam VASP_tetra UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PhenoGen Vasp PhenoGen
PIRSF Vasodilator_Phospo UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016367 RatGTEx
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF118370 UniProtKB/TrEMBL
UniProt A0A0G2K9C0_RAT UniProtKB/TrEMBL
  A0A8I6A7U4 ENTREZGENE
  A6J8L5 ENTREZGENE, UniProtKB/TrEMBL
  A6J8L6 ENTREZGENE, UniProtKB/TrEMBL
  B5DEX4 ENTREZGENE, UniProtKB/TrEMBL
  F7EWC1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Vasp  vasodilator-stimulated phosphoprotein   Vasp_predicted  vasodilator-stimulated phosphoprotein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Vasp_predicted  vasodilator-stimulated phosphoprotein (predicted)      Symbol and Name status set to approved 70820 APPROVED