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Gene: Col7a1 (collagen type VII alpha 1 chain) Rattus norvegicus

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Symbol:

Col7a1

Name:

collagen type VII alpha 1 chain

RGD ID:

1311417

Description:

Predicted to enable identical protein binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in collagen fibril organization. Predicted to be located in extracellular matrix and extracellular region. Predicted to be part of collagen trimer. Predicted to be active in basement membrane. Used to study recessive dystrophic epidermolysis bullosa. Human ortholog(s) of this gene implicated in epidermolysis bullosa dystrophica (multiple) and nonsyndromic congenital nail disorder 8. Orthologous to human COL7A1 (collagen type VII alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

collagen alpha-1(VII) chain; collagen, type VII, alpha 1; LOC301012; procollagen, type VII, alpha 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COL7A1 (collagen type VII alpha 1 chain)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Col7a1 (collagen, type VII, alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Col7a1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	COL7A1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COL7A1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Col7a1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COL7A1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COL7A1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Col7a1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Col7a1 (collagen type VII alpha 1 chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	COL7A1 (collagen type VII alpha 1 chain)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	COL7A1 (collagen type VII alpha 1 chain)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Col7a1 (collagen, type VII, alpha 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	col7a1 (collagen, type VII, alpha 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	col7a1 (collagen, type VII, alpha 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	col7a1l (collagen type VII alpha 1-like)	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	col7a1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Col7a1^em1Jtol

Genetic Models:

LEW-Col7a1^em1Jtol-/-

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	118,483,364 - 118,515,736 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	118,483,364 - 118,517,439 (+)	Ensembl				GRCr8
mRatBN7.2	8	109,604,877 - 109,637,249 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,604,861 - 109,637,252 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	115,222,418 - 115,254,812 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	113,421,605 - 113,453,999 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	111,264,400 - 111,296,794 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	8	119,370,236 - 119,402,636 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	121,475,177 - 121,507,578 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	119,964,899 - 119,997,300 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	111,367,042 - 111,399,437 (+)	NCBI		F344_StmMcwi
Rnor_6.0	8	117,694,441 - 117,726,844 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,694,605 - 117,726,844 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	117,046,218 - 117,078,589 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,971,207 - 114,003,445 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	108,898,754 - 108,930,986 (+)	NCBI		Celera
RGSC_v3.1	8	113,990,661 - 114,022,897 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amelogenesis imperfecta (ISO)

autosomal dominant dystrophic epidermolysis bullosa (ISO,ISS)

Breast Neoplasms (ISO)

Cicatrix (ISO)

Colorectal Neoplasms (ISO)

Disease Progression (ISO)

distal myopathy (ISO)

Duane retraction syndrome (ISO)

Dwarfism (ISO)

epidermolysis bullosa (ISO)

epidermolysis bullosa dystrophica (ISO)

Epidermolysis Bullosa Dystrophica, Autosomal Recessive, Localisata Variant (ISO)

Epidermolysis Bullosa Pruriginosa (ISO)

epidermolysis bullosa with congenital localized absence of skin and deformity of nails (ISO)

epidermolytic hyperkeratosis (ISO)

Failure to Thrive (ISO)

genetic disease (ISO)

hepatoblastoma (ISO)

Hyperpigmentation (ISO)

lung non-small cell carcinoma (ISO)

microcephaly (ISO)

nonsyndromic congenital nail disorder 4 (ISO)

nonsyndromic congenital nail disorder 8 (ISO)

pretibial dystrophic epidermolysis bullosa (ISO)

recessive dystrophic epidermolysis bullosa (IMP,ISO,ISS)

transient bullous dermolysis of the newborn (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-phenylprop-2-enal (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

acetylsalicylic acid (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

chlordecone (ISO)

chloropicrin (ISO)

clothianidin (ISO)

clotrimazole (EXP)

cobalt dichloride (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cortisol (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

diazepam (ISO)

dichloroacetic acid (ISO)

dimethylarsinic acid (ISO)

dimethylselenide (ISO)

dioxygen (ISO)

diuron (EXP)

dorsomorphin (ISO)

ethanol (ISO)

folic acid (ISO)

fucoxanthin (ISO)

furan (EXP)

gentamycin (EXP)

glucose (ISO)

graphite (EXP)

indometacin (ISO)

irinotecan (ISO)

lead diacetate (EXP)

manganese(II) chloride (EXP)

methimazole (EXP)

methylarsonic acid (ISO)

methylmercury chloride (EXP)

naled (ISO)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paclitaxel (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

progesterone (ISO)

quercetin (ISO)

reactive oxygen species (ISO)

resveratrol (ISO)

SB 431542 (ISO)

Se-methyl-L-selenocysteine (ISO)

Se-methylselenocysteine (ISO)

silver atom (ISO)

silver(0) (ISO)

simvastatin (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

sodium fluoride (ISO)

Soman (EXP)

streptozocin (ISO)

succimer (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

tributylstannane (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

Triptolide (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

collagen fibril organization (IMP)

digestion (IEA)

endodermal cell differentiation (IEA,ISO)

extracellular matrix organization (IBA)

signal transduction (IEA)

Cellular Component

basement membrane (IBA,IEA,ISO)

extracellular matrix (IEA)

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

corticotropin-releasing hormone receptor 2 binding (IEA)

extracellular matrix structural constituent conferring tensile strength (IBA)

hormone activity (IEA)

identical protein binding (ISO)

peptidase inhibitor activity (IEA)

protein binding (ISO)

serine-type endopeptidase inhibitor activity (IEA)

signaling receptor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

syndecan signaling pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

preweaning lethality, complete penetrance (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	A homozygous insertion-deletion in the type VII collagen gene (COL7A1) in Hallopeau-Siemens dystrophic epidermolysis bullosa.	Hilal L, etal., Nat Genet. 1993 Nov;5(3):287-93.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype.	Stone W, etal., PLoS One. 2024 May 9;19(5):e0302991. doi: 10.1371/journal.pone.0302991. eCollection 2024.

Additional References at PubMed

PMID:18757743	PMID:19651211	PMID:21570975	PMID:22664934	PMID:23154389	PMID:23717576

Genomics

Comparative Map Data

Col7a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	118,483,364 - 118,515,736 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	118,483,364 - 118,517,439 (+)	Ensembl				GRCr8
mRatBN7.2	8	109,604,877 - 109,637,249 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	109,604,861 - 109,637,252 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	115,222,418 - 115,254,812 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	113,421,605 - 113,453,999 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	111,264,400 - 111,296,794 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	8	119,370,236 - 119,402,636 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	8	121,475,177 - 121,507,578 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	8	119,964,899 - 119,997,300 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	8	111,367,042 - 111,399,437 (+)	NCBI		F344_StmMcwi
Rnor_6.0	8	117,694,441 - 117,726,844 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,694,605 - 117,726,844 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	117,046,218 - 117,078,589 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,971,207 - 114,003,445 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	108,898,754 - 108,930,986 (+)	NCBI		Celera
RGSC_v3.1	8	113,990,661 - 114,022,897 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

COL7A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	48,564,073 - 48,595,329 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	48,564,073 - 48,595,329 (-)	Ensembl			hg38	GRCh38
GRCh37	3	48,601,506 - 48,632,762 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	48,576,510 - 48,607,597 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	48,576,509 - 48,607,689	NCBI
Celera	3	48,557,241 - 48,588,335 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	48,659,828 - 48,690,843 (-)	NCBI		HuRef
CHM1_1	3	48,553,813 - 48,584,903 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	48,593,030 - 48,624,289 (-)	NCBI		T2T-CHM13v2.0

Col7a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	108,782,654 - 108,813,943 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	108,782,654 - 108,813,943 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	108,953,586 - 108,984,875 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,953,586 - 108,984,875 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	108,855,790 - 108,886,920 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	108,810,682 - 108,841,812 (+)	NCBI		MGSCv36	mm8
Celera	9	108,511,705 - 108,542,813 (+)	NCBI		Celera
Cytogenetic Map	9	F2	NCBI
cM Map	9	59.63	NCBI

Col7a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955532	650,913 - 681,186 (-)	NCBI	ChiLan1.0	ChiLan1.0

COL7A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	48,538,744 - 48,570,837 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	48,543,509 - 48,574,722 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	48,485,922 - 48,518,036 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	49,567,831 - 49,599,027 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	49,568,163 - 49,598,919 (-)	Ensembl			panPan2	panpan1.1

COL7A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	40,519,121 - 40,550,305 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	40,519,378 - 40,552,935 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	40,436,737 - 40,467,232 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	41,004,719 - 41,035,678 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	41,004,749 - 41,038,309 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	40,242,306 - 40,272,806 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	40,647,074 - 40,677,568 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	40,928,007 - 40,958,502 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Col7a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	63,588,441 - 63,621,451 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	349,267 - 381,701 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	348,938 - 381,701 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COL7A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	31,262,750 - 31,295,112 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	34,507,211 - 34,539,557 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COL7A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	9,964,652 - 9,996,785 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	9,964,651 - 9,996,626 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	157,089,010 - 157,121,213 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Col7a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	2,569,510 - 2,599,959 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Col7a1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	100,230,420 - 100,260,892 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Col7a1
447 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	201
Count of miRNA genes:	124
Interacting mature miRNAs:	148
Transcripts:	ENSRNOT00000027994
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

AW209154

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	118,515,598 - 118,515,692 (+)	Marker Load Pipeline
mRatBN7.2	8	109,637,111 - 109,637,204 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,726,704 - 117,726,796	NCBI	Rnor6.0
Rnor_5.0	8	117,078,449 - 117,078,541	UniSTS	Rnor5.0
RGSC_v3.4	8	114,003,305 - 114,003,397	UniSTS	RGSC3.4
Celera	8	108,930,846 - 108,930,938	UniSTS
Cytogenetic Map	8	q32	UniSTS

BI277776

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	109,636,975 - 109,637,170 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,726,568 - 117,726,762	NCBI	Rnor6.0
Rnor_5.0	8	117,078,313 - 117,078,507	UniSTS	Rnor5.0
RGSC_v3.4	8	114,003,169 - 114,003,363	UniSTS	RGSC3.4
Celera	8	108,930,710 - 108,930,904	UniSTS
RH 3.4 Map	8	1192.0	UniSTS
Cytogenetic Map	8	q32	UniSTS

Genetic Models

This gene Col7a1 is modified in the following models/strains:

LEW-Col7a1^em1Jtol-/-

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	16	12	150	243	77	76	51	94	45	22	424	286	11	222	79	92	31	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000027994 ⟹ ENSRNOP00000027994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	109,604,861 - 109,637,252 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,694,605 - 117,726,844 (+)	Ensembl

RefSeq Acc Id:

NM_001106858 ⟹ NP_001100328

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	118,483,364 - 118,515,736 (+)	NCBI
mRatBN7.2	8	109,604,877 - 109,637,249 (+)	NCBI
Dahl_SR_JrHsd	8	119,370,236 - 119,402,636 (+)	NCBI
Lyon_Normotensive	8	121,475,177 - 121,507,578 (+)	NCBI
Lyon_Hypertensive	8	119,964,899 - 119,997,300 (+)	NCBI
F344_StmMcwi	8	111,367,042 - 111,399,437 (+)	NCBI
Rnor_6.0	8	117,694,605 - 117,726,844 (+)	NCBI
Rnor_5.0	8	117,046,218 - 117,078,589 (+)	NCBI
RGSC_v3.4	8	113,971,207 - 114,003,445 (+)	RGD
Celera	8	108,898,754 - 108,930,986 (+)	RGD

Sequence:

show sequence

ATGAGGCTGCGGCTCCTGGTCGCTGCGCTCTGCACTGCCGAGATCCTGGTGGGGGCGCCCGGAG
TGTGGGCCCAGCCCAGAGATAGAGTGACCTGCACCCGCCTTTATGCTGCTGACATTGTGTTCTT
GATTGACGGCTCCTCGTCCATTGGCCGCAGCAACTTTCGAGAAGTGCGGGGATTCCTGGAGGGG
CTGGTGCTGCCTTTCTCAGGAGCAGCCAATGCACAGGGCGTCCGATTTGCAACAGTGCAGTACA
GTGATGATCCACAGACAGAATTTGGTCTGGATACACTTGGCTCTGGGGGTGACACCATTCGTGC
CATCCGGGAGCTCAGCTATAAGGGTGGTAACACTCGAACGGGGGCTGCTCTTCTCCACGTTTCC
GACCGGGTCTTCCTGCCTCATCTAACACGTCCTGGCATCCCCAAGGTCTGTATCCTGATCACAG
ATGGGAAATCCCAGGACTTAGTGGACACAGCTGCCCAAAAACTGAAGAGGCAGGGGGTCAAGCT
GTTTGCCGTGGGAATCAAGAACGCCGATCCTGAGGAACTGAAGCGCATCGCCTCACAGCCAACC
AGCGATTTCTTCTTCTTTGTCAATGACTTCAGCATCTTGAGGACCCTGTTGCCCCTCATTTCCC
GGAGGGTGTGCACCACGGCTGGTGGTGTGCCTGTGACCCTGCCTTCCGATGACACTCCGTCTGG
GCCCCGGGACCTGGTGCTGTCTGAGCCAAGTAGCCAATCCTTACGAGTACAGTGGACAGCAGCC
AGTGGCCCTGTGACTGGCTACAAAATTCAGTACACGCCCCTGACGGGGCTAGGACAGCCACTGC
CAAGTGAGCGAAAGGAGGTGAACGTCCCGGCTGGTGAGACCAGCATGCGACTACAGGGTCTCCG
GCCACTAACTGACTACCAAGTGACTGTGGTGGCCCTCTATGCTAACAGCATCGGAGAGGCTGTG
AGTGGGACAGCTCGGACCACTGCCAAGGAAGGGCTAGAGCTGAGCGTCCAGAACATCACATCCC
ACAGCCTCCTGGTGGCCTGGAGGAGGGTACCAGGTGCTAATGGCTACCGCGTAACATGGCGGGA
CCTCAGTGGTGGGGGGGCACAGCAGCAGGACCTGAGCCCTGGGCAGGGGTCAGTGTTTTTAGAT
CACTTGAAGCCTGGCACGGACTATGAGGTGACTGTGAGCGCCCTATTTGGCCGCAGCGTGGGGC
CTGCTGCTTCTCTGACTACCCGCACTGCCTCTTCTGTTGAGCAGACACTGCGCCCCATCATCCT
GAGCCCCACATCTATTCTCCTTTCCTGGAACTTGGTGCCTGAGGCCCGCGGCTACCGCCTGGAG
TGGCATCGTGAGAGTGGCTTGGAACCACCACAGAAAGTGGAACTGCTCCCTGATGTGACCCGCT
ACCAGTTGGATGGGTTGCAGCCAGGCACTGAGTATCGCCTCACGCTCTACACTCTGCTGGAGGG
CCGTGAGGTGGCCACTCCTGCGACTGTGGTTCCTACTGGGCTAGAGCAGCTGGTGGGCCCGGTG
ATGAATTTACAAGCCACAGAACTACCTGGGCAGCGGCTGCGAGTGTCTTGGAACCCAGTCCTCG
GTGCCACCGAGTACCGTTTCACTGTACGCACCCCCCAGGGGGTCGAGCGGACTTTGTTGCTTCC
TGGGAGTCAGACAACCTTTGACTTAGATGATGTTCGAGCCGGGATTAGCTACACAGTGCGAGTG
TCTGCTCGAGTGGGCACTCATGAGGGTGATGCCAGCACCCTCACCATCCACAGAGATCAAGAAG
CCCCACTTATTATCCCAGGACTGCAGGTTGTGGCATCAGATGCAACAAGAATTAGAGTGGCCTG
GGGACTTGTCCCTGGAGCCAGTGGATTTCGGATTAGCTGGAGGACAGGCAGTGGTCCAGAGTCC
AGTCAGACGCTGGCCCCAGACTCTACTGTCACAGACATCCTGGGGCTGCAGCCTGGAACCTCTT
ATCAAGTGGCTGTGTCAGCCCTTCGAGGGAGAGAAGAGGGGCCCCCTGTGGTCATCGTGGCTCG
AACTGATCCACTGGGCCCAGTGAGGAGAGTCCACTTGACTCAGGCTGGTAGCTCATCTGTCAGC
ATTACCTGGACTGGGGTTCCTGGCGCCACCGGATACAGGGTTTCCTGGCACTCAGGCCATGGTC
CAGAGAAATCTCAATTGGTTTCTGGGGACGCCACGGTGGCTGAAATAGATGGACTGGAGCCAGA
CACAGAGTATATAGTGCGTGTGAGAACCCATGTAGCCGGTGTGGATGGAGCCCCGGCCTCTGTG
GTTGTGAGGACTGCTCCTGAGCCTGTAGGCAGTGTGTCAAAACTGCAAATCCTTAATGCTTCCA
GTGATGTTCTCCGCGTCACTTGGGTGGGAGTCCCTGGAGCCACATCCTATAGACTGGCTTGGGG
ACGTAGTGAAGGTGGACCTATGAGACACCAGATAGTCCCAGGAAACAAAGACTCTGCAGAGATA
ACAGGTCTGGAAGGCGGAGTCAGCTACTCCGTGAGAGTGACGGCGCTTGTTGGAGACCGAGAGG
GTGCACCCGTGTCCATTGTCGTCACCACACCGCCTGAGGTCCCAGCACCTCTGGAGACCCTTCA
GGTAGTGCAGAGTGGGGAGCACTCCTTGAGGCTGCACTGGAACCGAGTCCCCGGAGCACAGGGC
TTCCGTCTGCATTGGCAACCTGAGGGTGGCCAGGAACAGTCCCTGACCTTGGGACCTGAGTCTA
ACAGCTACAACCTGGTCGGACTGGAGCCAGCAACGAAGTACCATGTATGGCTGAGTGTCCTGGG
CCAGCCTGGAGAAGCTGCCCCTAGGAAGGTGACTGCTTACACTGAGACTCCTCACATCCCGAGC
ACTGGGCTACGGGTGGTGGACACCTCTGTCAACTCAGTGACTTTGACCTGGACCCCAGTGTCTG
GGGCATCCAGCTATATCTTGTCCTGGCGGCCACTCAGAGGAACTGGCCAGGAAGTGCCGGGGGG
CCCGCAGACACTGCCAGGGAACTCAAGCTCCCACAGAGTGACAGGCCTGGAACCTGGGGTTCCC
TATGTTTTCTCTCTGACACCTATCCAGAGCGGTGTACGAGGTTCTGAGATCACTGTCACACAAA
AGCCAGCGTGTCCCCATGGCCAGGTGGACGTGGTGATCCTGTTACATGCCACTCGAGACAACGC
TCACAATGCAGAAGCTGTAAAGAGGTTCCTGGAAAGGCTGGTGTCTGCACTCGGGCCTCTTGGT
CCACAGGCTGCTCAGGTTGGCCTGCTGTCCTACAGCCACCGGCCCTCCCCACTGTTCCCGCTGA
ATAGTTCTCACGATCTTGGTGTCATCTTGCAAAAGATCCGTGACATCCCCTATGTGGACCCAAG
TGGTAACAACCTAGGCACAGCCGTGACCACAGCTCACAGATACCTCTTAGCACCCAATGCTCCC
GGTCGCCGTCGGCAAGTGCCAGGCGTGATGGTACTGTTAGTGGATGAACCTCTGAGAGAAGACA
TATTGAGCCCCATTCGTGAGGCCCAGGCTTCTGGGCTCAAGGTGATGATGCTGGGTCTGGTGGG
AGCTGACCCAGAGCAGCTGCGCCTCTTGGCACCAGGCATGGACCCCATCCAGACCTTCTTTGCT
GTGGATAATGGCTTAGACTTGGACCGAGCAGGCAGTGATCTGGCTGTAGCCCTATGTCAGGCAG
CTGTGGCCATACAGCCACAACTAGAGCCTTGTGCTGTGCCCTGTCCAAAGGGCCAGAAGGGGGA
GCCTGGAGTGACGGGACCGCAAGGACAGGCTGGACCTCCTGGTCCCCCCGGTCTCCCGGGCAGG
ACCGGTGCTCCAGGCCCACAAGGTGCTCCCGGAAGTACCCAAGCAAAAGGCGAGAGGGGCTTTC
CTGGCCCAGAAGGCCCTCCAGGCAGTCCTGGCCTACCTGGTGTTCCTGGGTCTCCTGGCGTTAA
GGGCTCCCCAGGGTGGTCTGGCCCTCGTGGGGATCGGGGAGAACGAGGGCCTCAAGGCCCAAAA
GGGGAGCCGGGGGAGCCTGGGCAAGTCATTGGAGGCGGAAGGCCAGGGCTTCCTGGAAAGAAAG
GGGACCCTGGACCTTCGGGACCCCCTGGACCTCATGGCCCTTTGGGGGACCCAGGACCTCGTGG
CCCCCCTGGGCTTCCTGGAACATCAGTGAAGGGTGACAAAGGTGACCGTGGGGAACGGGGTCCC
CCAGGACCAGGCACTGGTGCCAGTGAGCAAGGCAGCCCTGGACTTCCGGGGCTTCCTGGAAGCC
CTGGACCCCAAGGCCCACCTGGTCGAACTGGAGAGAAGGGAGAAAAGGGTGACTGTGAGGATGG
AGGCCCAGGCCTTCCAGGACAGCCTGGGGTTCCAGGGGAACCGGGCCTGCGGGGAGCTCCTGGA
GTTACTGGGCCCAAAGGTGATCGGGGACTGACAGGGACCCCGGGTGAGCCTGGAGAGAAGGGTG
AACGGGGACCACCTGGTCCCGTGGGACCCCAGGGGCTTCCCGGAGCTGCTGGACGTCCTGGAGT
GGAGGGTCCTGAGGGGCCACCAGGACCCCCTGGCCGCCGGGGAGAAAAGGGAGAGCCTGGTCGC
CCTGGGGATCCTGCATTGGGCCCTGGTGGTGCTGGAGCCAAGGGAGAAAAGGGAGATGCTGGGC
TCCCTGGGCCCAGAGGAGCTTCTGGAATCAAAGGAGAGCAGGGTGCACCTGGGTTGGCTCTTCC
TGGAGACCCTGGCCCCAAAGGAGACCCTGGAGACAGAGGTCCCATTGGCCTCACTGGCAGGGCA
GGACCCACAGGTGACTCAGGGCCTCCTGGAGAGAAGGGAGAACCTGGGCGACCTGGTTCCCCAG
GACCTGTTGGCCCTCGAGGAAGAGATGGTGAAGCTGGAGAGAAAGGTGACGAGGGTGCCCCGGG
TGAGCCAGGTTTGCCTGGAAAAGCAGGTGAACGCGGCCTCCGGGGGGCACCTGGGCCCCGGGGG
CCTGTGGGTGAGAAGGGGAATGAGGGGGATCCTGGAGAAGATGGCCGGAATGGCACCCCTGGAC
CATCTGGACCCAAGGGTGACCGTGGGGAGCCGGGCCCCCCGGGTCTCCCTGGACGGCTGGTGGA
TGCCGCCCTTGAATCCAGAGACAAGGGAGAGCCTGGACAGGAAGGTCCCCGAGGACCCAAGGGT
GACCCTGGCCCCCCTGGAGCCTCTGGAGAAAGGGGCATTGATGGGCTTCGGGGACCCCCAGGCC
CACAGGGAGACCCAGGTGTTCGAGGTCCTGCAGGAGACAAGGGTGATCGGGGATCCCCAGGGCT
GGATGGCCGAAATGGGCTAGATGGGAAACCAGGAGCCCCTGGCCCTCCAGGGCTACACGGTGCT
TCAGGGAAAGCTGGGGACCCTGGGAGAGATGGACTTCCAGGCCTTCGAGGAGAACATGGCCCAC
CTGGTCCCCCTGGCCCTCCTGGAGTACCGGGAAAGCCAGGCGATGACGGCAAACCCGGCCTGAA
TGGGAAAAACGGAGAACCTGGGGATCCCGGAGAAGATGGAAGGAAGGGAGAAAAGGGAGATTCG
GGTGTCCCTGGAAGGGAAGGTCCTGACGGTCCCAAGGGTGAACGCGGAGCTCCTGGTAATCCCG
GACTCCAGGGTCCTCCGGGTCTCCCAGGGCAGGTCGGTCCTCCCGGCCAGGGTTTCCCTGGTGT
CCCAGGAGTTACAGGTCCTAAGGGTGACCGTGGAGAGACTGGATCCAAAGGGGAACAGGGCCTT
CCTGGAGAACGTGGCCTACGAGGAGAACCGGGGAGCTTGCCGAATGCGGAGCGGTTCCTGGAAA
CTGCTGGCATCAAGGTGTCAGCCCTGCGGGAGATTGTGGACACCTGGGGTGAGAGTTCTGGCAG
CTTCCTGCTGGTGCCTGAGCGGAGACAAGGTCCCAAGGGGGACCCTGGTGACCCAGGCCCTCCA
GGCAAGGAGGGTTCCATTGGTCTTCCTGGAGAACGTGGGCTAAAGGGAGAACGAGGAGACCCTG
GCCCTCAGGGGCCTCCTGGTCTCGCCCTTGGTGAGAGGGGCCCACCTGGTCCATCTGGCCTTGC
CGGGGAACCAGGAAAGCCTGGAATTCCTGGGCTCCCAGGTCGGGCTGGGGCTGCAGGGGAAGCA
GGAAGGCCAGGAGAGAGGGGAGAAAGGGGAGAGAAAGGAGAACGCGGGGAACAGGGCAGAGATG
GCCATCCCGGCCTTCCTGGACCACCTGGCCCTCCTGGCCCCAAGGTGGCCATTGAAGAGCTAGG
TCCTGGACCCGCTAGAGAACAAGGACCTCCTGGACTCAAGGGTGCTAAGGGGGAGCCAGGCAGT
GATGGTGTCCCAGGACCCAAAGGAGACAGGGGTGTACCCGGCATCAAAGGAGATGCAGGAGAGC
CAGGAAAGAGGGGTCCTGATGGTAACCCAGGTCTGCCAGGAGAGCGCGGTGTGTCTGGACCTGA
AGGGAAGCCGGGTCTGCAGGGCCCGAGGGGGACCCCTGGCCCAGTGGGTAGCCATGGAGACCCA
GGACCACCTGGTGCCCCGGGTCTTGCTGGCCCTGCAGGGCCCCAGGGACCTTCTGGCCTGAAGG
GGGAGCCCGGAGAGACAGGACCCCCAGGACGGGGTCTGCCTGGACCTACTGGAGCTGTGGGACT
TCCTGGCCCTCCTGGCCCTTCAGGCCTCGTGGGCCCACAAGGCTCACCAGGTTTGCCCGGACAA
GTGGGGGAGACAGGGAAGCCAGGACCCCCAGGCCGGGATGGTAGCAGCGGAAAGGACGGAGAAA
GAGGAGGCCCTGGCGTGCCAGGGTTACCAGGTCTGCCCGGCCCTGTTGGACCTAAAGGAGAACC
TGGACCTGTGGGGGCCCCTGGACAGGTGGTGGTCGGGCCCCCTGGAGCAAAAGGCGAGAAGGGA
GCCCCAGGAGACCTTGCTGGAGCCCTGCTGGGTGAGCCGGGAGCCAAGGGTGACCGAGGACTGC
CTGGACCACGGGGTGAAAAGGGTGAAGCTGGCCATGCAGGAGAGCCTGGCGACCCTGGGGAAGA
TGGTCAAAAAGGGGCTCCAGGACTCAAAGGTCTCAAGGGCGAGCCAGGCATTGGGGTTCAGGGC
CCCCCTGGCCCAAGTGGTCCTCCAGGTATGAAGGGAGACTTGGGCCCCCCTGGTGCCCCCGGTG
CTCCTGGTATTGTTGGATTTCCTGGTCAGCCAGGACCTCGAGGAGAGACGGGCCAGCCAGGGCC
TGTTGGAGAGCGGGGTCTGGCAGGCCCTCCAGGGAGAGAAGGTGCCCCAGGTCCCTTGGGACCA
CCTGGACCACCGGGGTCAGTGGGAGCACCTGGCGCCTCTGGATTCAAAGGAGACAAGGGAGACT
CAGGAGCAGGGCTGCCAGGGCCCCGAGGCGAGCGTGGTGAACCAGGTCTCCGGGGTGAAGATGG
CCACCCTGGCCAGGAAGGACCTCGTGGACTCATGGGGCCCCCTGGCAGCCGGGGAGAGCGAGGA
GAGAAGGGCGACCCTGGTGCTGCAGGACTCAAGGGTGACAAGGGTGACTCAGCTGTGATTGAGG
GACCTGCAGGGCCACGAGGTGCCAAGGGGGATATGGGTGAACGAGGGCCTCGAGGCATAGATGG
TGACCAAGGACCTCGGGGTGAAAGTGGGGATCCTGGGGACAAGGGCTCCAAAGGAGAGCCTGGA
GACAAAGGCTCGGCTGGCTCCACTGGAGTTCGCGGACTCACAGGACCCAAGGCAAGGCGAGCCA
GGTGCTGCAGGGATCCCCGGTGAGCCGGGAGCCCCGGGAAAGGATGGAGCCCCTGGTTTCCGAG
GAGACAAAGGAGATATTGGCTTCACGGGTCCCAGGGGTCTCAAGGGTGAAAGAGGAGTAAAGGG
AACCTGTGGCCGTGACGGAGAGGAGAAGCTGGTTTTCCTGGTCGCCCTGGGTTGTCAGGAAAGA
AAGGAGACATGGGGGATCCTGGTATCCCGGGTCAGTCTGGGGCTCCTGGGAAAGAGGGGCTGAT
CGGTCCCAAGGGTGACAGAGGCTTTGATGGGCAGTCGGGGCCCAAGGGTGACCAAGGCGAGAAA
GGGGAGAGGGGGCCCCCAGGAGTTGGGGGCTTCCCAGGTCCCAGAGGAAATGATGGCTCTAGTG
GTCCCCCAGGGCCACCTGGTAGTATTGGTCCCAAGGGACCTGAAGGGCTTCAGGGTCAGAAGGG
TGAGCGAGGTCCCCCTGGAGAGAGTGTGGTGGGGGCTCCCGGTGCTCCTGGCACCCCTGGTGAG
AGAGGGGAACAGGGGCGACCGGGACCTGCCGGCCCCCGAGGGGAGAAAGGAGAAGCTGCACTGA
CTGAGGATGACATTCGGGGCTTTGTGCGTCAGGAGATGAGTCAGCATTGTGCCTGCCAGGGACA
GTTTATTGCGTCCGGATCACGACCCCTCCCTGGTTATGCTGCGGATACAGCTGGCCCCCAGCTC
CACCATGTTCCTGTGCTCCGGGTCTCTCACGTAGAGGAGGAAGGCCAGGTGCCCCCTGAAGACG
ATGACGACTTCTCTGAGTACTCCGTGTATTCTGTGGAGGACTACCAGGACCCTGAAGTTTCATG
GGATGGTGATGCCGAGACTAAGGGCTGGGACCATAGAGGCTCAGATCTCTGCTCCCTGCCACTG
GATGAGGGTTCCTGTACTGCCTATACCCTGCGCTGGTACCATCGAGCTGTACCTGGTGGCACAG
CGTGTCATCCCTTTGTCTACGGTGGCTGCAAGGGGAATGCTAATCGTTTTGGAACCCGTGAGGC
GTGCGAGCGCCGCTGCCCACCCCAAGGGGTCCACCGTCAGAACACAGGTGCTGCCTAGGGCTGA
GGCCCAGATGATGCACTTGGTGGCCAGCAATCCCTGGAGGTGGCAGGTCTCAGCCGGGTCCTGC
TATCCTCCATTTGGTGCTAGAGTTGTGTGTGCGCATGGGCGTGTGCACGTGTCCACTATTTCAG
TGACTTGGTCCTGTGGGTCTAGCCTTCCCCCCTGTGGACAAATCCCCATTGTGGCGCCCGCTTT
CCTGGCAGATGACTCACTGTTGGGGGTGGTTGTGGGCAGTGAATGGATGTGACTGGTGTCCAAC
CTGCCCCTTGACCCAAGGCTGTGATACCATGGTGCTGATGGGAGGGGAGGGGGGCATTAAAGCT
GCTGTTTTAAAAGGCCTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100328	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL77130	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000027994
	ENSRNOP00000027994.7
	ENSRNOP00000105792.1

RefSeq Acc Id:	NP_001100328 ⟸ NM_001106858
- Peptide Label:	precursor
- UniProtKB:	D3ZE04 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLRLLVAALCTAEILVGAPGVWAQPRDRVTCTRLYAADIVFLIDGSSSIGRSNFREVRGFLEG LVLPFSGAANAQGVRFATVQYSDDPQTEFGLDTLGSGGDTIRAIRELSYKGGNTRTGAALLHVS DRVFLPHLTRPGIPKVCILITDGKSQDLVDTAAQKLKRQGVKLFAVGIKNADPEELKRIASQPT SDFFFFVNDFSILRTLLPLISRRVCTTAGGVPVTLPSDDTPSGPRDLVLSEPSSQSLRVQWTAA SGPVTGYKIQYTPLTGLGQPLPSERKEVNVPAGETSMRLQGLRPLTDYQVTVVALYANSIGEAV SGTARTTAKEGLELSVQNITSHSLLVAWRRVPGANGYRVTWRDLSGGGAQQQDLSPGQGSVFLD HLKPGTDYEVTVSALFGRSVGPAASLTTRTASSVEQTLRPIILSPTSILLSWNLVPEARGYRLE WHRESGLEPPQKVELLPDVTRYQLDGLQPGTEYRLTLYTLLEGREVATPATVVPTGLEQLVGPV MNLQATELPGQRLRVSWNPVLGATEYRFTVRTPQGVERTLLLPGSQTTFDLDDVRAGISYTVRV SARVGTHEGDASTLTIHRDQEAPLIIPGLQVVASDATRIRVAWGLVPGASGFRISWRTGSGPES SQTLAPDSTVTDILGLQPGTSYQVAVSALRGREEGPPVVIVARTDPLGPVRRVHLTQAGSSSVS ITWTGVPGATGYRVSWHSGHGPEKSQLVSGDATVAEIDGLEPDTEYIVRVRTHVAGVDGAPASV VVRTAPEPVGSVSKLQILNASSDVLRVTWVGVPGATSYRLAWGRSEGGPMRHQIVPGNKDSAEI TGLEGGVSYSVRVTALVGDREGAPVSIVVTTPPEVPAPLETLQVVQSGEHSLRLHWNRVPGAQG FRLHWQPEGGQEQSLTLGPESNSYNLVGLEPATKYHVWLSVLGQPGEAAPRKVTAYTETPHIPS TGLRVVDTSVNSVTLTWTPVSGASSYILSWRPLRGTGQEVPGGPQTLPGNSSSHRVTGLEPGVP YVFSLTPIQSGVRGSEITVTQKPACPHGQVDVVILLHATRDNAHNAEAVKRFLERLVSALGPLG PQAAQVGLLSYSHRPSPLFPLNSSHDLGVILQKIRDIPYVDPSGNNLGTAVTTAHRYLLAPNAP GRRRQVPGVMVLLVDEPLREDILSPIREAQASGLKVMMLGLVGADPEQLRLLAPGMDPIQTFFA VDNGLDLDRAGSDLAVALCQAAVAIQPQLEPCAVPCPKGQKGEPGVTGPQGQAGPPGPPGLPGR TGAPGPQGAPGSTQAKGERGFPGPEGPPGSPGLPGVPGSPGVKGSPGWSGPRGDRGERGPQGPK GEPGEPGQVIGGGRPGLPGKKGDPGPSGPPGPHGPLGDPGPRGPPGLPGTSVKGDKGDRGERGP PGPGTGASEQGSPGLPGLPGSPGPQGPPGRTGEKGEKGDCEDGGPGLPGQPGVPGEPGLRGAPG VTGPKGDRGLTGTPGEPGEKGERGPPGPVGPQGLPGAAGRPGVEGPEGPPGPPGRRGEKGEPGR PGDPALGPGGAGAKGEKGDAGLPGPRGASGIKGEQGAPGLALPGDPGPKGDPGDRGPIGLTGRA GPTGDSGPPGEKGEPGRPGSPGPVGPRGRDGEAGEKGDEGAPGEPGLPGKAGERGLRGAPGPRG PVGEKGNEGDPGEDGRNGTPGPSGPKGDRGEPGPPGLPGRLVDAALESRDKGEPGQEGPRGPKG DPGPPGASGERGIDGLRGPPGPQGDPGVRGPAGDKGDRGSPGLDGRNGLDGKPGAPGPPGLHGA SGKAGDPGRDGLPGLRGEHGPPGPPGPPGVPGKPGDDGKPGLNGKNGEPGDPGEDGRKGEKGDS GVPGREGPDGPKGERGAPGNPGLQGPPGLPGQVGPPGQGFPGVPGVTGPKGDRGETGSKGEQGL PGERGLRGEPGSLPNAERFLETAGIKVSALREIVDTWGESSGSFLLVPERRQGPKGDPGDPGPP GKEGSIGLPGERGLKGERGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGAAGEA GRPGERGERGEKGERGEQGRDGHPGLPGPPGPPGPKVAIEELGPGPAREQGPPGLKGAKGEPGS DGVPGPKGDRGVPGIKGDAGEPGKRGPDGNPGLPGERGVSGPEGKPGLQGPRGTPGPVGSHGDP GPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLPGPTGAVGLPGPPGPSGLVGPQGSPGLPGQ VGETGKPGPPGRDGSSGKDGERGGPGVPGLPGLPGPVGPKGEPGPVGAPGQVVVGPPGAKGEKG APGDLAGALLGEPGAKGDRGLPGPRGEKGEAGHAGEPGDPGEDGQKGAPGLKGLKGEPGIGVQG PPGPSGPPGMKGDLGPPGAPGAPGIVGFPGQPGPRGETGQPGPVGERGLAGPPGREGAPGPLGP PGPPGSVGAPGASGFKGDKGDSGAGLPGPRGERGEPGLRGEDGHPGQEGPRGLMGPPGSRGERG EKGDPGAAGLKGDKGDSAVIEGPAGPRGAKGDMGERGPRGIDGDQGPRGESGDPGDKGSKGEPG DKGSAGSTGVRGLTGPKARRARCCRDPR hide sequence

Ensembl Acc Id:

ENSRNOP00000027994 ⟸ ENSRNOT00000027994

Protein Domains

BPTI/Kunitz inhibitor Fibronectin type-III VWFA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZE04-F1-model_v2	AlphaFold	D3ZE04	1-2588	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311417	AgrOrtholog
BioCyc Gene	G2FUF-29103	BioCyc
Ensembl Genes	ENSRNOG00000020579	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000027994	ENTREZGENE
	ENSRNOT00000027994.8	UniProtKB/TrEMBL
	ENSRNOT00000153275.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	4.10.410.10	UniProtKB/TrEMBL
InterPro	Collagen	UniProtKB/TrEMBL
	Collagen_superfamily	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	FN_III	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Kunitz_BPTI	UniProtKB/TrEMBL
	Kunitz_BPTI_sf	UniProtKB/TrEMBL
	Prtase_inh_Kunz-CS	UniProtKB/TrEMBL
	VWF_A	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:301012	UniProtKB/TrEMBL
NCBI Gene	301012	ENTREZGENE
PANTHER	COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED	UniProtKB/TrEMBL
	COLLAGEN ALPHA	UniProtKB/TrEMBL
Pfam	Collagen	UniProtKB/TrEMBL
	fn3	UniProtKB/TrEMBL
	Kunitz_BPTI	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
PhenoGen	Col7a1	PhenoGen
PRINTS	BASICPTASE	UniProtKB/TrEMBL
	VWFADOMAIN	UniProtKB/TrEMBL
PROSITE	BPTI_KUNITZ_1	UniProtKB/TrEMBL
	BPTI_KUNITZ_2	UniProtKB/TrEMBL
	FN3	UniProtKB/TrEMBL
	VWFA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000020579	RatGTEx
SMART	FN3	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
	SSF53300	UniProtKB/TrEMBL
	SSF57362	UniProtKB/TrEMBL
UniProt	A0ABK0LRI0_RAT	UniProtKB/TrEMBL
	A6I397_RAT	UniProtKB/TrEMBL
	D3ZE04	ENTREZGENE, UniProtKB/TrEMBL
	R9THZ8_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-27	Col7a1	collagen type VII alpha 1 chain	Col7a1	collagen, type VII, alpha 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-16	Col7a1	collagen, type VII, alpha 1	Col7a1	procollagen, type VII, alpha 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Col7a1	procollagen, type VII, alpha 1	Col7a1_predicted	procollagen, type VII, alpha 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Col7a1_predicted	procollagen, type VII, alpha 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Mammalian Phenotype