Dnai4 (dynein axonemal intermediate chain 4) - Rat Genome Database

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Gene: Dnai4 (dynein axonemal intermediate chain 4) Rattus norvegicus
Analyze
Symbol: Dnai4
Name: dynein axonemal intermediate chain 4
RGD ID: 1311027
Description: Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in axonemal dynein complex assembly and cilium movement. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in axoneme; dynein axonemal particle; and motile cilium. Predicted to be part of axonemal dynein complex. Orthologous to human DNAI4 (dynein axonemal intermediate chain 4); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dynein intermediate chain 4, axonemal; LOC313417; RGD1311027; similar to hypothetical protein MGC38950; WD repeat domain 78; WD repeat-containing protein 78; Wdr78
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,016,480 - 123,105,283 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)EnsemblGRCr8
mRatBN7.25117,787,398 - 117,876,216 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5117,788,464 - 117,876,127 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5120,420,400 - 120,508,962 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05122,145,751 - 122,234,315 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05122,197,015 - 122,285,581 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05122,551,370 - 122,642,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5122,551,405 - 122,642,202 (-)Ensemblrn6Rnor6.0
Rnor_5.05126,478,242 - 126,507,661 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.05126,419,821 - 126,471,244 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45123,959,144 - 124,048,268 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5116,363,303 - 116,447,865 (-)NCBICelera
RGSC_v3.15123,964,370 - 124,053,494 (-)NCBI
Cytogenetic Map5q33NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axonemal dynein complex  (IBA,IEA,ISO,ISS)
axoneme  (IEA,ISO,ISS)
dynein axonemal particle  (IEA,ISS)
motile cilium  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:24029230  


Genomics

Comparative Map Data
Dnai4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85123,016,480 - 123,105,283 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)EnsemblGRCr8
mRatBN7.25117,787,398 - 117,876,216 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5117,788,464 - 117,876,127 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5120,420,400 - 120,508,962 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05122,145,751 - 122,234,315 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05122,197,015 - 122,285,581 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05122,551,370 - 122,642,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5122,551,405 - 122,642,202 (-)Ensemblrn6Rnor6.0
Rnor_5.05126,478,242 - 126,507,661 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.05126,419,821 - 126,471,244 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45123,959,144 - 124,048,268 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5116,363,303 - 116,447,865 (-)NCBICelera
RGSC_v3.15123,964,370 - 124,053,494 (-)NCBI
Cytogenetic Map5q33NCBI
DNAI4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38166,812,885 - 66,924,856 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl166,812,885 - 66,924,890 (-)Ensemblhg38GRCh38
GRCh37167,278,568 - 67,390,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,051,156 - 67,163,158 (-)NCBIBuild 36Build 36hg18NCBI36
Celera165,568,539 - 65,680,519 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef165,386,832 - 65,499,349 (-)NCBIHuRef
CHM1_1167,393,937 - 67,505,926 (-)NCBICHM1_1
T2T-CHM13v2.0166,690,412 - 66,802,384 (-)NCBIT2T-CHM13v2.0
Dnai4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394102,891,954 - 102,971,524 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4102,895,262 - 102,971,752 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384103,038,065 - 103,114,299 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4103,038,065 - 103,114,555 (-)Ensemblmm10GRCm38
MGSCv374102,710,670 - 102,786,904 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364102,536,001 - 102,612,156 (-)NCBIMGSCv36mm8
Celera4101,402,744 - 101,478,812 (-)NCBICelera
Cytogenetic Map4C6NCBI
cM Map447.28NCBI
Dnai4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542324,027,924 - 24,089,914 (+)NCBIChiLan1.0ChiLan1.0
DNAI4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21159,935,133 - 160,047,820 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,095,149 - 159,208,006 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,061,390 - 66,174,221 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1167,946,717 - 68,059,640 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl167,953,276 - 68,059,625 (-)EnsemblpanPan2panpan1.1
DNAI4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1543,590,200 - 43,690,293 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl543,590,239 - 43,689,339 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha543,713,901 - 43,814,576 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0543,775,487 - 43,876,196 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl543,775,828 - 43,876,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1543,741,398 - 43,841,871 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0543,687,497 - 43,787,955 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0543,927,523 - 44,028,271 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnai4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505879,739,535 - 79,846,629 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365914,642,762 - 4,750,006 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAI4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6145,680,052 - 145,768,488 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16145,680,135 - 145,754,809 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNAI4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12066,189,698 - 66,295,628 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2066,189,723 - 66,294,478 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603351,300,092 - 51,405,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnai4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474228,100,838 - 28,181,385 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnai4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1151,467,401 - 51,542,939 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnai4
519 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:20
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000046691
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Mit6  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85123,046,109 - 123,046,321 (+)Marker Load Pipeline
mRatBN7.25117,817,033 - 117,817,245 (+)MAPPERmRatBN7.2
Rnor_6.05122,581,410 - 122,581,621NCBIRnor6.0
Rnor_5.05126,448,845 - 126,449,056UniSTSRnor5.0
RGSC_v3.45123,988,261 - 123,988,473RGDRGSC3.4
RGSC_v3.45123,988,262 - 123,988,473UniSTSRGSC3.4
Celera5116,391,573 - 116,391,779UniSTS
RGSC_v3.15123,993,483 - 123,993,804RGD
SHRSP x BN Map563.7699RGD
SHRSP x BN Map563.7699UniSTS
Cytogenetic Map5q34UniSTS
BF388268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25117,877,303 - 117,877,489 (+)MAPPERmRatBN7.2
Rnor_6.05122,643,338 - 122,643,523NCBIRnor6.0
Rnor_5.05126,508,838 - 126,509,023UniSTSRnor5.0
RGSC_v3.45124,049,445 - 124,049,630UniSTSRGSC3.4
Celera5116,449,042 - 116,449,227UniSTS
Cytogenetic Map5q34UniSTS
RH138978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25117,875,950 - 117,876,072 (+)MAPPERmRatBN7.2
Rnor_6.05122,641,985 - 122,642,106NCBIRnor6.0
Rnor_5.05126,507,485 - 126,507,606UniSTSRnor5.0
RGSC_v3.45124,048,092 - 124,048,213UniSTSRGSC3.4
Celera5116,447,689 - 116,447,810UniSTS
RH 3.4 Map5754.6UniSTS
Cytogenetic Map5q34UniSTS
AU049090  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25117,790,595 - 117,790,875 (+)MAPPERmRatBN7.2
Rnor_6.05122,554,566 - 122,554,845NCBIRnor6.0
Rnor_5.05126,421,954 - 126,422,233UniSTSRnor5.0
RGSC_v3.45123,961,277 - 123,961,556UniSTSRGSC3.4
Celera5116,365,436 - 116,365,715UniSTS
Cytogenetic Map5q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 165 91 90 59 91 59 6 354 190 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000046691   ⟹   ENSRNOP00000048851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,023,728 - 123,090,746 (-)Ensembl
mRatBN7.2 Ensembl5117,788,464 - 117,876,127 (-)Ensembl
Rnor_6.0 Ensembl5122,551,405 - 122,642,202 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101086   ⟹   ENSRNOP00000097541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,024,462 - 123,105,283 (-)Ensembl
mRatBN7.2 Ensembl5117,788,464 - 117,876,127 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115287   ⟹   ENSRNOP00000089481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)Ensembl
mRatBN7.2 Ensembl5117,793,754 - 117,861,679 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117003   ⟹   ENSRNOP00000095528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)Ensembl
mRatBN7.2 Ensembl5117,788,464 - 117,876,127 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000127153   ⟹   ENSRNOP00000100351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129945   ⟹   ENSRNOP00000106569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5123,016,480 - 123,105,283 (-)Ensembl
RefSeq Acc Id: NM_001024786   ⟹   NP_001019957
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,105,283 (-)NCBI
mRatBN7.25117,787,402 - 117,876,216 (-)NCBI
Rnor_6.05122,552,433 - 122,642,161 (-)NCBI
Rnor_5.05126,419,821 - 126,471,244 (-)NCBI
Rnor_5.05126,478,242 - 126,507,661 (-)NCBI
RGSC_v3.45123,959,144 - 124,048,268 (-)RGD
Celera5116,363,303 - 116,447,865 (-)RGD
Sequence:
RefSeq Acc Id: XM_008763872   ⟹   XP_008762094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,105,208 (-)NCBI
mRatBN7.25117,787,398 - 117,876,140 (-)NCBI
Rnor_6.05122,551,370 - 122,642,156 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109947   ⟹   XP_038965875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,056,378 (-)NCBI
mRatBN7.25117,787,398 - 117,827,314 (-)NCBI
RefSeq Acc Id: XM_063287690   ⟹   XP_063143760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,105,208 (-)NCBI
RefSeq Acc Id: XM_063287691   ⟹   XP_063143761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,105,208 (-)NCBI
RefSeq Acc Id: XM_063287692   ⟹   XP_063143762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85123,016,480 - 123,105,208 (-)NCBI
RefSeq Acc Id: NP_001019957   ⟸   NM_001024786
- UniProtKB: Q5XIP5 (UniProtKB/Swiss-Prot),   Q4V8G4 (UniProtKB/Swiss-Prot),   A0A8L2QPC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762094   ⟸   XM_008763872
- Peptide Label: isoform X3
- UniProtKB: A0A8L2QPC1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000048851   ⟸   ENSRNOT00000046691
RefSeq Acc Id: XP_038965875   ⟸   XM_039109947
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000095528   ⟸   ENSRNOT00000117003
Ensembl Acc Id: ENSRNOP00000089481   ⟸   ENSRNOT00000115287
Ensembl Acc Id: ENSRNOP00000097541   ⟸   ENSRNOT00000101086
RefSeq Acc Id: XP_063143762   ⟸   XM_063287692
- Peptide Label: isoform X4
- UniProtKB: A0A8I6B2X4 (UniProtKB/TrEMBL),   A0A8L2QPC1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143760   ⟸   XM_063287690
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QPC1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143761   ⟸   XM_063287691
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QPC1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106569   ⟸   ENSRNOT00000129945
Ensembl Acc Id: ENSRNOP00000100351   ⟸   ENSRNOT00000127153

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8G4-F1-model_v2 AlphaFold Q4V8G4 1-803 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693864
Promoter ID:EPDNEW_R4389
Type:initiation region
Name:Wdr78_1
Description:WD repeat domain 78
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05122,642,173 - 122,642,233EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311027 AgrOrtholog
BioCyc Gene G2FUF-40509 BioCyc
Ensembl Genes ENSRNOG00000006999 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000115287 ENTREZGENE
  ENSRNOT00000117003 ENTREZGENE
  ENSRNOT00000127153 ENTREZGENE
  ENSRNOT00000129945 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134424 IMAGE-MGC_LOAD
  IMAGE:7453940 IMAGE-MGC_LOAD
InterPro Dynein_IC UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:313417 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114447 IMAGE-MGC_LOAD
  MGC:94427 IMAGE-MGC_LOAD
NCBI Gene 313417 ENTREZGENE
PANTHER DYNEIN AXONEMAL INTERMEDIATE CHAIN 4 UniProtKB/Swiss-Prot
  DYNEIN INTERMEDIATE CHAIN UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Dnai4 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006999 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8I6ACQ7_RAT UniProtKB/TrEMBL
  A0A8I6AWH4_RAT UniProtKB/TrEMBL
  A0A8I6B2X4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QPC1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LJF3_RAT UniProtKB/TrEMBL
  A0ABK0LLQ1_RAT UniProtKB/TrEMBL
  Q4V8G4 ENTREZGENE
  Q5XIP5 ENTREZGENE
  WDR78_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5XIP5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-05-22 Dnai4  dynein axonemal intermediate chain 4  Wdr78  WD repeat domain 78  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Wdr78  WD repeat domain 78  RGD1311027  similar to hypothetical protein MGC38950  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1311027  similar to hypothetical protein MGC38950  RGD1311027_predicted  similar to hypothetical protein MGC38950 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311027_predicted  similar to hypothetical protein MGC38950 (predicted)  LOC313417_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313417_predicted  similar to hypothetical protein MGC38950 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL