Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gmds | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of GMDS mRNA | CTD | PMID:22298810 | Gmds | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GMDS mRNA | CTD | PMID:32109520|PMID:34747641 | Gmds | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GMDS mRNA | CTD | PMID:20106945|PMID:21632981 | Gmds | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gmds (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GMDS mRNA | CTD | PMID:21570461 | Gmds | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of GMDS mRNA | CTD | PMID:32109520 | Gmds | Rat | 2-methylcholine | affects expression | ISO | GMDS (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of GMDS mRNA | CTD | PMID:21179406 | Gmds | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | GMDS (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of GMDS gene | CTD | PMID:31601247 | Gmds | Rat | 5-aza-2'-deoxycytidine | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Decitabine results in decreased expression of GMDS mRNA | CTD | PMID:19194470 | Gmds | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of GMDS mRNA | CTD | PMID:30047161 | Gmds | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of GMDS mRNA | CTD | PMID:32553695 | Gmds | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of GMDS mRNA | CTD | PMID:31881176 | Gmds | Rat | aflatoxin B1 | affects expression | ISO | GMDS (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of GMDS protein | CTD | PMID:20106945 | Gmds | Rat | aflatoxin B1 | affects methylation | ISO | GMDS (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of GMDS intron | CTD | PMID:30157460 | Gmds | Rat | aflatoxin B1 | increases methylation | ISO | GMDS (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of GMDS gene | CTD | PMID:31555880 | Gmds | Rat | aflatoxin B1 | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of GMDS mRNA | CTD | PMID:22100608|PMID:27153756|PMID:31555880|PMID:32234424 | Gmds | Rat | aflatoxin B1 | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of GMDS mRNA | CTD | PMID:19770486 | Gmds | Rat | Aflatoxin B2 alpha | increases methylation | ISO | GMDS (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of GMDS intron | CTD | PMID:30157460 | Gmds | Rat | antirheumatic drug | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of GMDS mRNA | CTD | PMID:24449571 | Gmds | Rat | aristolochic acid A | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of GMDS mRNA | CTD | PMID:33212167 | Gmds | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of GMDS gene | CTD | PMID:28931070 | Gmds | Rat | Azoxymethane | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GMDS more ... | CTD | PMID:29950665 | Gmds | Rat | benzo[a]pyrene | increases expression | ISO | Gmds (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of GMDS mRNA | CTD | PMID:22228805 | Gmds | Rat | benzo[a]pyrene | affects methylation | ISO | GMDS (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GMDS intron | CTD | PMID:30157460 | Gmds | Rat | benzo[a]pyrene | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of GMDS mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291|PMID:31555880|PMID:32234424 | Gmds | Rat | benzo[a]pyrene | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of GMDS mRNA | CTD | PMID:19770486|PMID:20713471|PMID:21715664|PMID:25908611 | Gmds | Rat | benzo[a]pyrene | increases methylation | ISO | GMDS (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of GMDS gene | CTD | PMID:31555880 | Gmds | Rat | benzo[e]pyrene | affects methylation | ISO | GMDS (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of GMDS intron | CTD | PMID:30157460 | Gmds | Rat | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GMDS mRNA | CTD | PMID:18164116 | Gmds | Rat | beta-naphthoflavone | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | beta-Naphthoflavone results in increased expression of GMDS protein | CTD | PMID:39638853 | Gmds | Rat | bisphenol A | increases expression | ISO | Gmds (Mus musculus) | 6480464 | bisphenol A results in increased expression of GMDS mRNA | CTD | PMID:26063408|PMID:32156529 | Gmds | Rat | bisphenol A | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GMDS protein | CTD | PMID:37567409 | Gmds | Rat | bisphenol A | decreases methylation | ISO | GMDS (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GMDS gene | CTD | PMID:31601247 | Gmds | Rat | bisphenol A | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GMDS gene | CTD | PMID:31601247 | Gmds | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GMDS mRNA | CTD | PMID:34947998 | Gmds | Rat | bisphenol A | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | bisphenol A results in increased expression of GMDS mRNA | CTD | PMID:29275510 | Gmds | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GMDS mRNA | CTD | PMID:25181051 | Gmds | Rat | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GMDS more ... | CTD | PMID:39012411 | Gmds | Rat | cadmium atom | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GMDS more ... | CTD | PMID:37236586 | Gmds | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GMDS more ... | CTD | PMID:39012411 | Gmds | Rat | cadmium dichloride | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GMDS more ... | CTD | PMID:37236586 | Gmds | Rat | carbon nanotube | increases expression | ISO | Gmds (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of GMDS mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Gmds | Rat | CGP 52608 | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GMDS gene] | CTD | PMID:28238834 | Gmds | Rat | chlordecone | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Chlordecone results in decreased expression of GMDS mRNA | CTD | PMID:33711761 | Gmds | Rat | chromium(6+) | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... | CTD | PMID:38479592 | Gmds | Rat | cisplatin | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of GMDS mRNA | CTD | PMID:19561079|PMID:27392435|PMID:27594783 | Gmds | Rat | cisplatin | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of GMDS mRNA | CTD | PMID:27392435 | Gmds | Rat | cobalt dichloride | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of GMDS mRNA | CTD | PMID:19376846 | Gmds | Rat | copper(II) sulfate | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of GMDS mRNA | CTD | PMID:19549813 | Gmds | Rat | cyclosporin A | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of GMDS mRNA | CTD | PMID:27989131 | Gmds | Rat | dexamethasone | increases expression | ISO | Gmds (Mus musculus) | 6480464 | Dexamethasone results in increased expression of GMDS mRNA | CTD | PMID:22733784 | Gmds | Rat | dextran sulfate | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GMDS more ... | CTD | PMID:29950665 | Gmds | Rat | diazinon | increases methylation | ISO | GMDS (Homo sapiens) | 6480464 | Diazinon results in increased methylation of GMDS gene | CTD | PMID:22964155 | Gmds | Rat | dichloroacetic acid | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Dichloroacetic Acid results in decreased expression of GMDS mRNA | CTD | PMID:28962523 | Gmds | Rat | dioxygen | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GMDS mRNA | CTD | PMID:30529165 | Gmds | Rat | dorsomorphin | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gmds | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of GMDS mRNA | CTD | PMID:29391264 | Gmds | Rat | enzalutamide | affects expression | ISO | GMDS (Homo sapiens) | 6480464 | enzalutamide affects the expression of GMDS mRNA | CTD | PMID:30940724 | Gmds | Rat | enzyme inhibitor | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Gmds | Rat | epoxiconazole | increases expression | ISO | Gmds (Mus musculus) | 6480464 | epoxiconazole results in increased expression of GMDS mRNA | CTD | PMID:35436446 | Gmds | Rat | ethyl methanesulfonate | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of GMDS mRNA | CTD | PMID:23649840 | Gmds | Rat | formaldehyde | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of GMDS mRNA | CTD | PMID:23649840 | Gmds | Rat | fulvestrant | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GMDS gene | CTD | PMID:31601247 | Gmds | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of GMDS mRNA | CTD | PMID:27387713 | Gmds | Rat | GDP | affects binding | ISO | GMDS (Homo sapiens) | 6480464 | Guanosine Diphosphate binds to GMDS protein | CTD | PMID:25526675 | Gmds | Rat | genistein | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Genistein results in decreased expression of GMDS mRNA | CTD | PMID:32186404 | Gmds | Rat | guanosine 5'-[beta,gamma-imido]triphosphate | affects binding | ISO | GMDS (Homo sapiens) | 6480464 | Guanylyl Imidodiphosphate binds to GMDS protein | CTD | PMID:25526675 | Gmds | Rat | guanosine 5'-monophosphate | affects binding | ISO | GMDS (Homo sapiens) | 6480464 | Guanosine Monophosphate binds to GMDS protein | CTD | PMID:25526675 | Gmds | Rat | methapyrilene | affects methylation | ISO | GMDS (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of GMDS intron | CTD | PMID:30157460 | Gmds | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of GMDS mRNA | CTD | PMID:30047161 | Gmds | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of GMDS gene | CTD | PMID:35440735 | Gmds | Rat | methyl methanesulfonate | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of GMDS mRNA | CTD | PMID:23649840 | Gmds | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of GMDS gene | CTD | PMID:33148267 | Gmds | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GMDS mRNA | CTD | PMID:18164116 | Gmds | Rat | N-Nitrosopyrrolidine | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of GMDS mRNA | CTD | PMID:32234424 | Gmds | Rat | NADP zwitterion | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | NADP binds to and results in increased activity of GMDS protein | CTD | PMID:25526675 | Gmds | Rat | NADP(+) | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | NADP binds to and results in increased activity of GMDS protein | CTD | PMID:25526675 | Gmds | Rat | O-methyleugenol | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of GMDS mRNA | CTD | PMID:32234424 | Gmds | Rat | ochratoxin A | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | ochratoxin A results in increased expression of GMDS protein | CTD | PMID:39638853 | Gmds | Rat | okadaic acid | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of GMDS mRNA | CTD | PMID:38832940 | Gmds | Rat | ozone | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Gmds | Rat | ozone | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of GMDS mRNA | CTD | PMID:35430440 | Gmds | Rat | paracetamol | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GMDS mRNA | CTD | PMID:22230336|PMID:26690555 | Gmds | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of GMDS gene | CTD | PMID:33148267 | Gmds | Rat | phenobarbital | affects expression | ISO | Gmds (Mus musculus) | 6480464 | Phenobarbital affects the expression of GMDS mRNA | CTD | PMID:23091169 | Gmds | Rat | pirinixic acid | increases expression | ISO | Gmds (Mus musculus) | 6480464 | pirinixic acid results in increased expression of GMDS mRNA | CTD | PMID:18301758 | Gmds | Rat | propiconazole | increases expression | ISO | Gmds (Mus musculus) | 6480464 | propiconazole results in increased expression of GMDS mRNA | CTD | PMID:21278054 | Gmds | Rat | quercetin | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Quercetin results in decreased expression of GMDS mRNA | CTD | PMID:21632981 | Gmds | Rat | SB 431542 | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gmds | Rat | silicon dioxide | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of GMDS mRNA | CTD | PMID:25895662 | Gmds | Rat | sodium arsenite | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GMDS mRNA | CTD | PMID:38568856 | Gmds | Rat | sodium fluoride | increases expression | ISO | Gmds (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of GMDS protein | CTD | PMID:28918527 | Gmds | Rat | sulforaphane | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of GMDS mRNA | CTD | PMID:31838189 | Gmds | Rat | temozolomide | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | Temozolomide results in increased expression of GMDS mRNA | CTD | PMID:31758290 | Gmds | Rat | testosterone | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Testosterone results in decreased expression of GMDS mRNA | CTD | PMID:33359661 | Gmds | Rat | thimerosal | decreases expression | ISO | GMDS (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of GMDS mRNA | CTD | PMID:27188386 | Gmds | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GMDS mRNA | CTD | PMID:34492290 | Gmds | Rat | titanium dioxide | multiple interactions | ISO | Gmds (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GMDS more ... | CTD | PMID:29950665 | Gmds | Rat | titanium dioxide | decreases methylation | ISO | Gmds (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of GMDS gene | CTD | PMID:35295148 | Gmds | Rat | topotecan | affects response to substance | ISO | GMDS (Homo sapiens) | 6480464 | GMDS protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | Gmds | Rat | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of GMDS protein | CTD | PMID:32519852 | Gmds | Rat | valproic acid | affects expression | ISO | GMDS (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GMDS mRNA | CTD | PMID:25979313 | Gmds | Rat | valproic acid | multiple interactions | ISO | GMDS (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Gmds | Rat | valproic acid | increases expression | ISO | GMDS (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GMDS mRNA | CTD | PMID:23179753|PMID:25192806|PMID:26272509|PMID:28001369|PMID:29154799 | Gmds | Rat | vancomycin | decreases expression | ISO | Gmds (Mus musculus) | 6480464 | Vancomycin results in decreased expression of GMDS mRNA | CTD | PMID:18930951 | |






















