Usp45 (ubiquitin specific peptidase 45) - Rat Genome Database

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Gene: Usp45 (ubiquitin specific peptidase 45) Rattus norvegicus
Analyze
Symbol: Usp45
Name: ubiquitin specific peptidase 45
RGD ID: 1310976
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cell migration and photoreceptor cell maintenance. Predicted to act upstream of or within DNA repair and protein deubiquitination. Predicted to be located in cytoplasm; nucleus; and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 19. Orthologous to human USP45 (ubiquitin specific peptidase 45); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313098; ubiquitin carboxyl-terminal hydrolase 45; ubiquitin specific petidase 45; ubiquitin specific protease 45
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,115,394 - 40,188,861 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,115,267 - 40,188,861 (+)EnsemblGRCr8
mRatBN7.2535,318,621 - 35,392,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx537,442,950 - 37,516,428 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,035,678 - 39,109,156 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0538,975,187 - 39,048,666 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0535,916,763 - 35,984,525 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl535,916,804 - 35,984,524 (+)Ensemblrn6Rnor6.0
Rnor_5.0540,573,111 - 40,639,487 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4536,517,213 - 36,590,986 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera534,335,326 - 34,403,408 (+)NCBICelera
RGSC_v3.1536,502,821 - 36,587,983 (+)NCBI
Cytogenetic Map5q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
photoreceptor inner segment  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14715245   PMID:25538220   PMID:30573563  


Genomics

Comparative Map Data
Usp45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,115,394 - 40,188,861 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,115,267 - 40,188,861 (+)EnsemblGRCr8
mRatBN7.2535,318,621 - 35,392,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx537,442,950 - 37,516,428 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,035,678 - 39,109,156 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0538,975,187 - 39,048,666 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0535,916,763 - 35,984,525 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl535,916,804 - 35,984,524 (+)Ensemblrn6Rnor6.0
Rnor_5.0540,573,111 - 40,639,487 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4536,517,213 - 36,590,986 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera534,335,326 - 34,403,408 (+)NCBICelera
RGSC_v3.1536,502,821 - 36,587,983 (+)NCBI
Cytogenetic Map5q21NCBI
USP45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38699,432,325 - 99,517,846 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl699,432,325 - 99,521,728 (-)Ensemblhg38GRCh38
GRCh37699,880,201 - 99,963,299 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36699,986,903 - 100,069,973 (-)NCBIBuild 36Build 36hg18NCBI36
Celera6100,524,338 - 100,607,389 (-)NCBICelera
Cytogenetic Map6q16.2NCBI
HuRef697,320,605 - 97,403,620 (-)NCBIHuRef
CHM1_16100,143,216 - 100,226,233 (-)NCBICHM1_1
T2T-CHM13v2.06100,606,672 - 100,692,182 (-)NCBIT2T-CHM13v2.0
Usp45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39421,767,161 - 21,837,872 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl421,767,156 - 21,837,872 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38421,767,161 - 21,837,872 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl421,767,156 - 21,837,872 (+)Ensemblmm10GRCm38
MGSCv37421,703,417 - 21,765,019 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36421,867,134 - 21,928,707 (+)NCBIMGSCv36mm8
Celera421,521,282 - 21,582,575 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map48.93NCBI
Usp45
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541125,316,535 - 25,378,573 (-)Ensembl
ChiLan1.0NW_00495541125,315,536 - 25,375,283 (-)NCBIChiLan1.0ChiLan1.0
USP45
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25119,479,099 - 119,562,643 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16117,357,233 - 117,443,835 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16101,155,903 - 101,239,145 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6101,155,903 - 101,238,682 (-)EnsemblpanPan2panpan1.1
USP45
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,637,890 - 57,706,562 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1257,642,515 - 57,706,511 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1257,396,662 - 57,468,813 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01258,460,557 - 58,533,263 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1258,500,488 - 58,533,253 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11257,817,618 - 57,889,705 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01257,662,704 - 57,736,494 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01257,907,902 - 57,981,807 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Usp45
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,576,117 - 92,663,981 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366511,037,804 - 1,119,399 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366511,031,328 - 1,119,344 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP45
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl166,387,608 - 66,454,737 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1166,387,616 - 66,454,806 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,067,349 - 75,131,522 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP45
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11374,368,043 - 74,434,884 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1374,362,564 - 74,438,133 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604046,695,092 - 46,768,332 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp45
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248105,508,882 - 5,574,395 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248105,508,912 - 5,574,233 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Usp45
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11121,500,672 - 121,565,541 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Usp45
659 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:398
Count of miRNA genes:228
Interacting mature miRNAs:273
Transcripts:ENSRNOT00000066043
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)53113042148841739Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
AU015084  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,320,665 - 35,320,777 (+)MAPPERmRatBN7.2
Rnor_6.0535,918,816 - 35,918,927NCBIRnor6.0
Rnor_5.0540,575,342 - 40,575,453UniSTSRnor5.0
RGSC_v3.4536,519,201 - 36,519,312UniSTSRGSC3.4
Celera534,337,357 - 34,337,468UniSTS
Cytogenetic Map5q21UniSTS
BF399437  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,371,967 - 35,372,128 (+)MAPPERmRatBN7.2
Rnor_6.0535,967,091 - 35,967,251NCBIRnor6.0
Rnor_5.0540,622,096 - 40,622,256UniSTSRnor5.0
RGSC_v3.4536,573,544 - 36,573,704UniSTSRGSC3.4
Celera534,386,072 - 34,386,232UniSTS
RH 3.4 Map5166.0UniSTS
Cytogenetic Map5q21UniSTS
AI843191  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,916,905 - 53,917,002 (+)MAPPERmRatBN7.2
mRatBN7.2535,388,965 - 35,389,062 (-)MAPPERmRatBN7.2
mRatBN7.2535,388,965 - 35,389,062 (+)MAPPERmRatBN7.2
mRatBN7.2753,916,905 - 53,917,002 (-)MAPPERmRatBN7.2
Rnor_6.0535,984,070 - 35,984,166NCBIRnor6.0
Rnor_6.0761,350,948 - 61,351,044NCBIRnor6.0
Rnor_5.0540,639,032 - 40,639,128UniSTSRnor5.0
Rnor_5.0761,347,169 - 61,347,265UniSTSRnor5.0
RGSC_v3.4536,590,532 - 36,590,628UniSTSRGSC3.4
RGSC_v3.4757,635,321 - 57,635,417UniSTSRGSC3.4
Celera534,402,954 - 34,403,050UniSTS
Cytogenetic Map5q21UniSTS
RH137368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,916,654 - 53,916,873 (+)MAPPERmRatBN7.2
mRatBN7.2535,389,094 - 35,389,313 (-)MAPPERmRatBN7.2
mRatBN7.2753,916,654 - 53,916,873 (-)MAPPERmRatBN7.2
mRatBN7.2535,389,094 - 35,389,313 (+)MAPPERmRatBN7.2
Rnor_6.0761,350,697 - 61,350,915NCBIRnor6.0
Rnor_6.0535,984,199 - 35,984,417NCBIRnor6.0
Rnor_5.0761,346,918 - 61,347,136UniSTSRnor5.0
Rnor_5.0540,639,161 - 40,639,379UniSTSRnor5.0
RGSC_v3.4536,590,661 - 36,590,879UniSTSRGSC3.4
RGSC_v3.4757,635,070 - 57,635,288UniSTSRGSC3.4
Celera534,403,083 - 34,403,301UniSTS
RH 3.4 Map5165.5UniSTS
Cytogenetic Map5q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000066043   ⟹   ENSRNOP00000060364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)Ensembl
Rnor_6.0 Ensembl535,916,804 - 35,984,524 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083132   ⟹   ENSRNOP00000073155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl540,115,267 - 40,188,861 (+)Ensembl
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)Ensembl
Rnor_6.0 Ensembl535,916,819 - 35,981,378 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108204   ⟹   ENSRNOP00000092813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl540,115,439 - 40,183,191 (+)Ensembl
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)Ensembl
RefSeq Acc Id: NM_001395561   ⟹   NP_001382490
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,115,409 - 40,188,861 (+)NCBI
mRatBN7.2535,318,635 - 35,392,090 (+)NCBI
RefSeq Acc Id: XM_006237939   ⟹   XP_006238001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,115,426 - 40,186,192 (+)NCBI
mRatBN7.2535,318,640 - 35,392,090 (+)NCBI
Rnor_6.0535,916,777 - 35,984,525 (+)NCBI
Rnor_5.0540,573,111 - 40,639,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237940   ⟹   XP_006238002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,115,394 - 40,186,192 (+)NCBI
mRatBN7.2535,318,621 - 35,392,090 (+)NCBI
Rnor_6.0535,916,764 - 35,984,525 (+)NCBI
Rnor_5.0540,573,111 - 40,639,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237941   ⟹   XP_006238003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,115,394 - 40,186,192 (+)NCBI
mRatBN7.2535,318,621 - 35,392,090 (+)NCBI
Rnor_6.0535,916,763 - 35,984,525 (+)NCBI
Rnor_5.0540,573,111 - 40,639,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109812   ⟹   XP_038965740
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,115,426 - 40,186,192 (+)NCBI
mRatBN7.2535,318,640 - 35,392,090 (+)NCBI
RefSeq Acc Id: XM_039109813   ⟹   XP_038965741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,137,292 - 40,186,192 (+)NCBI
mRatBN7.2535,340,516 - 35,392,090 (+)NCBI
RefSeq Acc Id: XP_006238003   ⟸   XM_006237941
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AG99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238002   ⟸   XM_006237940
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006238001   ⟸   XM_006237939
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4S7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060364   ⟸   ENSRNOT00000066043
Ensembl Acc Id: ENSRNOP00000073155   ⟸   ENSRNOT00000083132
RefSeq Acc Id: XP_038965740   ⟸   XM_039109812
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965741   ⟸   XM_039109813
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000092813   ⟸   ENSRNOT00000108204
RefSeq Acc Id: NP_001382490   ⟸   NM_001395561
- UniProtKB: A0A0G2K4S7 (UniProtKB/TrEMBL)
Protein Domains
UBP-type   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4S7-F1-model_v2 AlphaFold A0A0G2K4S7 1-813 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693596
Promoter ID:EPDNEW_R4121
Type:multiple initiation site
Name:Usp45_1
Description:ubiquitin specific peptidase 45
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0535,916,813 - 35,916,873EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310976 AgrOrtholog
BioCyc Gene G2FUF-41814 BioCyc
Ensembl Genes ENSRNOG00000008688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083132 ENTREZGENE
  ENSRNOT00000083132.3 UniProtKB/TrEMBL
  ENSRNOT00000108204 ENTREZGENE
  ENSRNOT00000108204.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Pept_C19ubi-hydrolase_C_CS UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  UCH/PAN2 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene 313098 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 45 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PhenoGen Usp45 PhenoGen
PROSITE UCH_2_1 UniProtKB/TrEMBL
  UCH_2_2 UniProtKB/TrEMBL
  UCH_2_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008688 RatGTEx
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A0G2K4S7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AG99 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Usp45  ubiquitin specific peptidase 45  Usp45  ubiquitin specific petidase 45   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Usp45  ubiquitin specific petidase 45   Usp45_predicted  ubiquitin specific petidase 45 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Usp45_predicted  ubiquitin specific petidase 45 (predicted)    ubiquitin specific protease 45 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Usp45_predicted  ubiquitin specific protease 45 (predicted)      Symbol and Name status set to approved 70820 APPROVED