USP45 (ubiquitin specific peptidase 45) - Rat Genome Database

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Gene: USP45 (ubiquitin specific peptidase 45) Pan paniscus
Analyze
Symbol: USP45
Name: ubiquitin specific peptidase 45
RGD ID: 11710129
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); metal ion binding (inferred); INVOLVED IN DNA repair (ortholog); protein deubiquitination (ortholog); ASSOCIATED WITH Dwarfism (ortholog); Leber congenital amaurosis 19 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 45
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25119,479,099 - 119,562,643 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16117,357,233 - 117,443,835 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16101,155,903 - 101,239,145 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6101,155,903 - 101,238,682 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
USP45
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25119,479,099 - 119,562,643 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16117,357,233 - 117,443,835 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16101,155,903 - 101,239,145 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6101,155,903 - 101,238,682 (-)Ensemblpanpan1.1panPan2
USP45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38699,432,325 - 99,517,846 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl699,432,325 - 99,521,728 (-)EnsemblGRCh38hg38GRCh38
GRCh37699,880,201 - 99,963,299 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36699,986,903 - 100,069,973 (-)NCBINCBI36Build 36hg18NCBI36
Celera6100,524,338 - 100,607,389 (-)NCBICelera
Cytogenetic Map6q16.2NCBI
HuRef697,320,605 - 97,403,620 (-)NCBIHuRef
CHM1_16100,143,216 - 100,226,233 (-)NCBICHM1_1
T2T-CHM13v2.06100,606,672 - 100,692,182 (-)NCBIT2T-CHM13v2.0
Usp45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39421,767,161 - 21,837,872 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl421,767,156 - 21,837,872 (+)EnsemblGRCm39 Ensembl
GRCm38421,767,161 - 21,837,872 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl421,767,156 - 21,837,872 (+)EnsemblGRCm38mm10GRCm38
MGSCv37421,703,417 - 21,765,019 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36421,867,134 - 21,928,707 (+)NCBIMGSCv36mm8
Celera421,521,282 - 21,582,575 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map48.93NCBI
Usp45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,115,394 - 40,188,861 (+)NCBIGRCr8
mRatBN7.2535,318,621 - 35,392,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,318,635 - 35,389,420 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx537,442,950 - 37,516,428 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,035,678 - 39,109,156 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0538,975,187 - 39,048,666 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0535,916,763 - 35,984,525 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl535,916,804 - 35,984,524 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0540,573,111 - 40,639,487 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4536,517,213 - 36,590,986 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1536,502,821 - 36,587,983 (+)NCBI
Celera534,335,326 - 34,403,408 (+)NCBICelera
Cytogenetic Map5q21NCBI
Usp45
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541125,316,535 - 25,378,573 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541125,315,536 - 25,375,283 (-)NCBIChiLan1.0ChiLan1.0
USP45
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,637,890 - 57,706,562 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1257,642,515 - 57,706,511 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1257,396,662 - 57,468,813 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01258,460,557 - 58,533,263 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11257,817,618 - 57,889,705 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01257,662,704 - 57,736,494 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01257,907,902 - 57,981,807 (-)NCBIUU_Cfam_GSD_1.0
Usp45
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,576,117 - 92,663,981 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366511,037,804 - 1,119,399 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366511,031,328 - 1,119,344 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP45
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl166,387,608 - 66,454,737 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1166,387,616 - 66,454,806 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,067,349 - 75,131,522 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP45
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11374,368,043 - 74,434,884 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1374,362,564 - 74,438,133 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604046,695,092 - 46,768,332 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp45
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248105,508,882 - 5,574,395 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248105,508,912 - 5,574,233 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045549   ⟹   ENSPPAP00000022735
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6101,155,903 - 101,238,682 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000045559   ⟹   ENSPPAP00000022746
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6101,159,302 - 101,233,630 (-)Ensembl
RefSeq Acc Id: XM_003824359   ⟹   XP_003824407
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25119,479,099 - 119,562,638 (-)NCBI
NHGRI_mPanPan16117,357,233 - 117,443,162 (-)NCBI
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBI
PanPan1.16101,155,903 - 101,238,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008978087   ⟹   XP_008976335
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25119,479,099 - 119,562,638 (-)NCBI
NHGRI_mPanPan16117,357,233 - 117,443,835 (-)NCBI
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBI
PanPan1.16101,155,903 - 101,239,145 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008978088   ⟹   XP_008976336
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25119,479,099 - 119,562,643 (-)NCBI
NHGRI_mPanPan16117,357,233 - 117,443,162 (-)NCBI
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBI
PanPan1.16101,155,903 - 101,238,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034962582   ⟹   XP_034818473
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25119,479,099 - 119,562,636 (-)NCBI
NHGRI_mPanPan16117,357,233 - 117,443,162 (-)NCBI
Mhudiblu_PPA_v0697,273,498 - 97,356,749 (-)NCBI
RefSeq Acc Id: XM_055113979   ⟹   XP_054969954
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25119,479,099 - 119,529,460 (-)NCBI
NHGRI_mPanPan16117,357,233 - 117,410,632 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008976335   ⟸   XM_008978087
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AZS7 (UniProtKB/TrEMBL),   A0A2R9B5W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976336   ⟸   XM_008978088
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B5W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003824407   ⟸   XM_003824359
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AZS7 (UniProtKB/TrEMBL),   A0A2R9B5W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818473   ⟸   XM_034962582
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B5W5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000022735   ⟸   ENSPPAT00000045549
RefSeq Acc Id: ENSPPAP00000022746   ⟸   ENSPPAT00000045559
RefSeq Acc Id: XP_054969954   ⟸   XM_055113979
- Peptide Label: isoform X4
Protein Domains
UBP-type   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034506 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045549.1 UniProtKB/TrEMBL
  ENSPPAT00000045559.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report pps:100988629 UniProtKB/TrEMBL
NCBI Gene USP45 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 45 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9AZS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B5W5 ENTREZGENE, UniProtKB/TrEMBL