Daglb (diacylglycerol lipase, beta) - Rat Genome Database

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Gene: Daglb (diacylglycerol lipase, beta) Rattus norvegicus
Analyze
Symbol: Daglb
Name: diacylglycerol lipase, beta
RGD ID: 1310193
Description: Predicted to enable monoacylglycerol lipase activity and triacylglycerol lipase activity. Predicted to be involved in several processes, including diacylglycerol catabolic process; positive regulation of triglyceride catabolic process; and unsaturated fatty acid metabolic process. Predicted to act upstream of or within cannabinoid biosynthetic process; monoacylglycerol biosynthetic process; and neuroblast proliferation. Predicted to be located in nucleoplasm. Predicted to be active in plasma membrane. Orthologous to human DAGLB (diacylglycerol lipase beta); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; ethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DAGL-beta; DGL-beta; diacylglycerol lipase-beta; LOC304289; PUFA-specific triacylglycerol lipase; RGD1310193; similar to KCCR13L; sn1-specific diacylglycerol lipase beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,173,345 - 16,215,777 (-)NCBIGRCr8
mRatBN7.21211,059,732 - 11,102,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,059,732 - 11,102,154 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,866,990 - 11,909,058 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,490,279 - 12,532,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,515,614 - 11,558,372 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,113,073 - 13,157,748 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,113,237 - 13,157,666 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,156,222 - 15,198,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,403,012 - 11,446,588 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,433,671 - 11,476,434 (-)NCBI
Celera1212,853,805 - 12,895,732 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-stearoyl-2-arachidonoyl-sn-glycerol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
fenthion  (ISO)
finasteride  (EXP)
fluoxetine  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
Methylazoxymethanol acetate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses. Hsu KL, etal., Nat Chem Biol. 2012 Dec;8(12):999-1007. doi: 10.1038/nchembio.1105. Epub 2012 Oct 28.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages. Shin M, etal., Cell Chem Biol. 2020 Mar 19;27(3):314-321.e5. doi: 10.1016/j.chembiol.2020.01.005. Epub 2020 Jan 27.
Additional References at PubMed
PMID:14610053   PMID:15057822   PMID:16051747   PMID:17897319   PMID:20147530   PMID:37366545  


Genomics

Comparative Map Data
Daglb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,173,345 - 16,215,777 (-)NCBIGRCr8
mRatBN7.21211,059,732 - 11,102,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,059,732 - 11,102,154 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,866,990 - 11,909,058 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,490,279 - 12,532,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,515,614 - 11,558,372 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,113,073 - 13,157,748 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,113,237 - 13,157,666 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,156,222 - 15,198,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,403,012 - 11,446,588 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11211,433,671 - 11,476,434 (-)NCBI
Celera1212,853,805 - 12,895,732 (-)NCBICelera
Cytogenetic Map12p11NCBI
DAGLB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3876,409,129 - 6,447,954 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl76,409,126 - 6,484,190 (-)EnsemblGRCh38hg38GRCh38
GRCh3776,448,760 - 6,487,585 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3676,415,285 - 6,454,110 (-)NCBINCBI36Build 36hg18NCBI36
Celera76,247,497 - 6,286,391 (+)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef76,321,636 - 6,360,470 (-)NCBIHuRef
CHM1_176,448,302 - 6,487,218 (-)NCBICHM1_1
T2T-CHM13v2.076,528,530 - 6,567,278 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v276,495,031 - 6,533,770 (-)NCBI
Daglb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395143,450,239 - 143,490,197 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5143,450,339 - 143,491,697 (+)EnsemblGRCm39 Ensembl
GRCm385143,464,484 - 143,504,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5143,464,584 - 143,505,942 (+)EnsemblGRCm38mm10GRCm38
MGSCv375144,225,361 - 144,265,310 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365143,728,563 - 143,759,811 (+)NCBIMGSCv36mm8
Celera5140,510,811 - 140,551,153 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map582.19NCBI
Daglb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546013,226,693 - 13,267,449 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546013,226,574 - 13,268,060 (+)NCBIChiLan1.0ChiLan1.0
DAGLB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2611,222,644 - 11,262,021 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1759,547,340 - 59,586,729 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v076,995,425 - 7,034,279 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.176,604,541 - 6,631,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl76,605,250 - 6,634,169 (-)Ensemblpanpan1.1panPan2
DAGLB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1611,761,470 - 11,791,936 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl611,761,788 - 11,791,838 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha613,384,556 - 13,417,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0611,760,015 - 11,794,150 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl611,758,960 - 11,794,159 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1611,635,851 - 11,669,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0611,615,639 - 11,649,550 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0611,843,572 - 11,876,293 (-)NCBIUU_Cfam_GSD_1.0
Daglb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344139,839,363 - 139,927,862 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493675078,548 - 105,281 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493675017,411 - 105,436 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAGLB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,741,747 - 4,779,557 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,741,882 - 4,779,210 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DAGLB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12815,616,744 - 15,660,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2815,617,459 - 15,659,291 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666102415,702 - 454,814 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Daglb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474030,880,253 - 30,909,448 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474030,880,252 - 30,912,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Daglb
466 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:234
Count of miRNA genes:104
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000001437, ENSRNOT00000067332
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat

Markers in Region
D12Rat43  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,073,825 - 11,074,078 (+)MAPPERmRatBN7.2
Rnor_6.01213,127,211 - 13,127,463NCBIRnor6.0
Rnor_5.01215,169,677 - 15,169,929UniSTSRnor5.0
RGSC_v3.41211,416,955 - 11,417,208RGDRGSC3.4
RGSC_v3.41211,416,956 - 11,417,208UniSTSRGSC3.4
RGSC_v3.11211,446,884 - 11,447,136RGD
Celera1212,867,560 - 12,867,812UniSTS
RH 3.4 Map12151.7UniSTS
RH 3.4 Map12151.7RGD
RH 2.0 Map12118.0RGD
SHRSP x BN Map1213.63RGD
Cytogenetic Map12p11UniSTS
D12Rat34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,067,517 - 11,067,730 (+)MAPPERmRatBN7.2
Rnor_6.01213,120,859 - 13,121,071NCBIRnor6.0
Rnor_5.01215,164,008 - 15,164,220UniSTSRnor5.0
RGSC_v3.41211,410,797 - 11,411,010RGDRGSC3.4
RGSC_v3.41211,410,798 - 11,411,010UniSTSRGSC3.4
RGSC_v3.11211,440,725 - 11,440,938RGD
Celera1212,861,593 - 12,861,805UniSTS
RH 2.0 Map12111.8RGD
SHRSP x BN Map1212.67RGD
Cytogenetic Map12p11UniSTS
RH134838  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,096,862 - 11,097,076 (+)MAPPERmRatBN7.2
Rnor_6.01213,152,361 - 13,152,574NCBIRnor6.0
Rnor_5.01215,192,745 - 15,192,958UniSTSRnor5.0
RGSC_v3.41211,441,297 - 11,441,510UniSTSRGSC3.4
Celera1212,890,441 - 12,890,654UniSTS
Cytogenetic Map12p11UniSTS
UniSTS:498230  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21211,059,374 - 11,059,850 (+)MAPPERmRatBN7.2
Rnor_6.01213,112,716 - 13,113,191NCBIRnor6.0
Rnor_5.01215,155,865 - 15,156,340UniSTSRnor5.0
RGSC_v3.41211,402,655 - 11,403,130UniSTSRGSC3.4
Celera1212,853,448 - 12,853,923UniSTS
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001437   ⟹   ENSRNOP00000001437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1213,114,003 - 13,157,570 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000067332   ⟹   ENSRNOP00000062663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1211,059,732 - 11,102,154 (-)Ensembl
Rnor_6.0 Ensembl1213,114,003 - 13,157,570 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092238   ⟹   ENSRNOP00000075753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1213,142,239 - 13,157,666 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092292   ⟹   ENSRNOP00000075840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1211,059,732 - 11,102,154 (-)Ensembl
Rnor_6.0 Ensembl1213,113,237 - 13,133,219 (-)Ensembl
RefSeq Acc Id: NM_001107120   ⟹   NP_001100590
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,173,345 - 16,215,758 (-)NCBI
mRatBN7.21211,059,732 - 11,102,154 (-)NCBI
Rnor_6.01213,113,073 - 13,157,652 (-)NCBI
Rnor_5.01215,156,222 - 15,198,036 (-)NCBI
RGSC_v3.41211,403,012 - 11,446,588 (-)RGD
Celera1212,853,805 - 12,895,732 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089357   ⟹   XP_038945285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,176,808 - 16,215,769 (-)NCBI
mRatBN7.21211,063,195 - 11,102,170 (-)NCBI
RefSeq Acc Id: XM_039089358   ⟹   XP_038945286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,173,513 - 16,213,156 (-)NCBI
mRatBN7.21211,059,900 - 11,099,555 (-)NCBI
RefSeq Acc Id: XM_063271256   ⟹   XP_063127326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,173,513 - 16,215,777 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100590 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945285 (Get FASTA)   NCBI Sequence Viewer  
  XP_038945286 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127326 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89667 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000062663.4
  ENSRNOP00000075840.2
GenBank Protein P0C1S9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001100590   ⟸   NM_001107120
- UniProtKB: P0C1S9 (UniProtKB/Swiss-Prot),   A0A0U1RRW6 (UniProtKB/TrEMBL),   A6K1K9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000062663   ⟸   ENSRNOT00000067332
Ensembl Acc Id: ENSRNOP00000075840   ⟸   ENSRNOT00000092292
Ensembl Acc Id: ENSRNOP00000075753   ⟸   ENSRNOT00000092238
Ensembl Acc Id: ENSRNOP00000001437   ⟸   ENSRNOT00000001437
RefSeq Acc Id: XP_038945286   ⟸   XM_039089358
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038945285   ⟸   XM_039089357
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063127326   ⟸   XM_063271256
- Peptide Label: isoform X3
Protein Domains
Fungal lipase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C1S9-F1-model_v2 AlphaFold P0C1S9 1-668 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698443
Promoter ID:EPDNEW_R8963
Type:initiation region
Name:Daglb_1
Description:diacylglycerol lipase, beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01213,157,666 - 13,157,726EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310193 AgrOrtholog
BioCyc Gene G2FUF-20007 BioCyc
BioCyc Pathway LIPAS-PWY [triacylglycerol degradation] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image LIPAS-PWY BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000001079 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067332.5 UniProtKB/TrEMBL
  ENSRNOT00000092292.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG_Lipase-Related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fungal_lipase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:304289 UniProtKB/TrEMBL
NCBI Gene 304289 ENTREZGENE
PANTHER DIACYLGLYCEROL LIPASE HOMOLOG-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIACYLGLYCEROL LIPASE-BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lipase_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Daglb PhenoGen
PROSITE LIPASE_SER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001079 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RRW6 ENTREZGENE, UniProtKB/TrEMBL
  A6K1K9 ENTREZGENE, UniProtKB/TrEMBL
  D3Z890_RAT UniProtKB/TrEMBL
  DGLB_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Daglb  diacylglycerol lipase, beta  RGD1310193_predicted  similar to KCCR13L (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1310193_predicted  similar to KCCR13L (predicted)  LOC304289_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304289_predicted  similar to KCCR13L (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL